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Page 1
Percutaneous Closure of Patent Ductus Arteriosus.
Barcroft M, McKee C, Berman DP, Taylor RA, Rivera BK, Smith CV, Slaughter JL, El-Khuffash A, Backes CH. Barcroft M, et al. Clin Perinatol. 2022 Mar;49(1):149-166. doi: 10.1016/j.clp.2021.11.009. Epub 2022 Jan 21. Clin Perinatol. 2022. PMID: 35209997 Free PMC article. Review.
Reply to correspondence.
El-Khuffash A, McNamara P. El-Khuffash A, et al. J Perinatol. 2022 May;42(5):693-694. doi: 10.1038/s41372-021-01235-y. Epub 2021 Nov 2. J Perinatol. 2022. PMID: 34728824 No abstract available.
Haematological parameters and coagulation in umbilical cord blood following COVID-19 infection in pregnancy.
Murphy CA, O'Reilly DP, Edebiri O, Weiss L, Cullivan S, El-Khuffash A, Doyle E, Donnelly JC, Malone FD, Ferguson W, Drew RJ, O'Loughlin J, Neary E, Maguire PB, Kevane B, NíAinle F, McCallion N. Murphy CA, et al. Eur J Obstet Gynecol Reprod Biol. 2021 Nov;266:99-105. doi: 10.1016/j.ejogrb.2021.09.019. Epub 2021 Sep 21. Eur J Obstet Gynecol Reprod Biol. 2021. PMID: 34601263 Free PMC article.
Early targeted patent ductus arteriosus treatment in premature neonates using a risk based severity score: study protocol for a randomised controlled trial (PDA RCT).
El-Khuffash A, Bussmann N, Breatnach CR, Smith A, Tully E, Griffin J, McCallion N, Corcoran JD, Fernandez E, Looi C, Cleary B, Franklin O, McNamara PJ. El-Khuffash A, et al. HRB Open Res. 2020 Nov 25;3:87. doi: 10.12688/hrbopenres.13140.1. eCollection 2020. HRB Open Res. 2020. PMID: 34522836 Free PMC article.
Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown.
Rasmussen MI, Hansen ML, Pichler G, Dempsey E, Pellicer A, El-Khuffash A, A S, Piris-Borregas S, Alsina M, Cetinkaya M, Chalak L, Özkan H, Baserga M, Sirc J, Fuchs H, Ergenekon E, Arruza L, Mathur A, Stocker M, Otero Vaccarello O, Szczapa T, Sarafidis K, Królak-Olejnik B, Memisoglu A, Reigstad H, Rafińska-Ważny E, Hatzidaki E, Peng Z, Gkentzi D, Viellevoye R, De Buyst J, Mastretta E, Wang P, Hahn GH, Bender L, Cornette L, Tkaczyk J, Del Rio R, Fumagalli M, Papathoma E, Wilinska M, Naulaers G, Sadowska-Krawczenko I, Lecart C, Couce ML, Fredly S, Heuchan AM, Karen T, Greisen G. Rasmussen MI, et al. Front Pediatr. 2021 Jul 12;9:647880. doi: 10.3389/fped.2021.647880. eCollection 2021. Front Pediatr. 2021. PMID: 34322460 Free PMC article.
Neurodevelopmental outcome following hypoxic ischaemic encephalopathy and therapeutic hypothermia is related to right ventricular performance at 24-hour postnatal age.
Giesinger RE, El Shahed AI, Castaldo MP, Bischoff AR, Chau V, Whyte HEA, El-Khuffash AF, Mertens L, McNamara PJ. Giesinger RE, et al. Arch Dis Child Fetal Neonatal Ed. 2022 Jan;107(1):70-75. doi: 10.1136/archdischild-2020-321463. Epub 2021 May 27. Arch Dis Child Fetal Neonatal Ed. 2022. PMID: 34045280
Cerebral oxygen saturation and autoregulation during hypotension in extremely preterm infants.
Thewissen L, Naulaers G, Hendrikx D, Caicedo A, Barrington K, Boylan G, Cheung PY, Corcoran D, El-Khuffash A, Garvey A, Macko J, Marlow N, Miletin J, O'Donnell CPF, O'Toole JM, Straňák Z, Van Laere D, Wiedermannova H, Dempsey E. Thewissen L, et al. Pediatr Res. 2021 Aug;90(2):373-380. doi: 10.1038/s41390-021-01483-w. Epub 2021 Apr 20. Pediatr Res. 2021. PMID: 33879849 Clinical Trial.
Multicentre prospective observational study exploring the predictive value of functional echocardiographic indices for early identification of preterm neonates at risk of developing chronic pulmonary hypertension secondary to chronic neonatal lung disease.
Thomas L, Baczynski M, Deshpande P, Kharrat A, Joye S, Zhu F, Ibarra-Rios D, Shah PS, Mertens L, Jankov RP, Ye XY, Neary E, Ting J, Castaldo M, Levy P, Smith A, El-Khuffash AF, Giesinger RE, McNamara PJ, Weisz DE, Jain A. Thomas L, et al. BMJ Open. 2021 Mar 31;11(3):e044924. doi: 10.1136/bmjopen-2020-044924. BMJ Open. 2021. PMID: 33789855 Free PMC article.
Altered inflammasome activation in neonatal encephalopathy persists in childhood.
Kelly LA, O'Dea MI, Zareen Z, Melo AM, McKenna E, Strickland T, McEneaney V, Donoghue V, Boylan G, Sweetman D, Butler J, Vavasseur C, Miletin J, El-Khuffash AF, O'Neill LAJ, O'Leary JJ, Molloy EJ. Kelly LA, et al. Clin Exp Immunol. 2021 Jul;205(1):89-97. doi: 10.1111/cei.13598. Epub 2021 May 2. Clin Exp Immunol. 2021. PMID: 33768526 Free PMC article.
Hypotension in Preterm Infants (HIP) randomised trial.
Dempsey EM, Barrington KJ, Marlow N, O'Donnell CPF, Miletin J, Naulaers G, Cheung PY, Corcoran JD, El-Khuffash AF, Boylan GB, Livingstone V, Pons G, Macko J, Van Laere D, Wiedermannova H, Straňák Z; HIP consortium. Dempsey EM, et al. Arch Dis Child Fetal Neonatal Ed. 2021 Jul;106(4):398-403. doi: 10.1136/archdischild-2020-320241. Epub 2021 Feb 24. Arch Dis Child Fetal Neonatal Ed. 2021. PMID: 33627329 Free PMC article. Clinical Trial.
Calling into question the future of hyperoxygenation in pregnancy.
McHugh A, El-Khuffash A, Franklin O, Breathnach FM. McHugh A, et al. Eur J Obstet Gynecol Reprod Biol. 2021 Mar;258:93-97. doi: 10.1016/j.ejogrb.2020.12.054. Epub 2020 Dec 31. Eur J Obstet Gynecol Reprod Biol. 2021. PMID: 33421817 Review.
Intervention and Outcome for Neonatal Hypotension.
Barrington K, El-Khuffash A, Dempsey E. Barrington K, et al. Clin Perinatol. 2020 Sep;47(3):563-574. doi: 10.1016/j.clp.2020.05.011. Epub 2020 May 20. Clin Perinatol. 2020. PMID: 32713451 Free article. Review.
Multiorgan involvement and management in children with Down syndrome.
Lagan N, Huggard D, Mc Grane F, Leahy TR, Franklin O, Roche E, Webb D, O' Marcaigh A, Cox D, El-Khuffash A, Greally P, Balfe J, Molloy EJ. Lagan N, et al. Acta Paediatr. 2020 Jun;109(6):1096-1111. doi: 10.1111/apa.15153. Epub 2020 Jan 24. Acta Paediatr. 2020. PMID: 31899550 Review.
Toward the elimination of bias in Pediatric Research.
Bearer C, Agostoni C, Anand KJS, Ambalavanan N, Bhandari V, Bliss JM, Bloomfield F, Bonifacio SL, Buhimschi I, Cilio MR, Coppes M, Czinn SJ, El-Khuffash A, Embleton N, Felderhoff-Müser U, Ferriero DM, Florin T, Fuentes-Afflick E, Gardner W, Gospe SM Jr, Gunn A, Gressens P, Guissani D, Haiden N, Hauptman M, Kim KS, Klebanoff M, Lachman P, Lanphear B, Ozen S, Roehr C, Roland D, Rosenblum N, Schwarz M, Staiano A, Stroustrup A, Valente EM, Wilson-Costello D, Wynn J, Molloy E. Bearer C, et al. Pediatr Res. 2019 Dec;86(6):680-681. doi: 10.1038/s41390-019-0583-5. Epub 2019 Sep 18. Pediatr Res. 2019. PMID: 31533126 Free article. No abstract available.
Echocardiographic Assessment of Right Ventricular Afterload in Preterm Infants: Maturational Patterns of Pulmonary Artery Acceleration Time Over the First Year of Age and Implications for Pulmonary Hypertension.
Patel MD, Breatnach CR, James AT, Choudhry S, McNamara PJ, Jain A, Franklin O, Hamvas A, Mertens L, Singh GK, El-Khuffash A, Levy PT. Patel MD, et al. J Am Soc Echocardiogr. 2019 Jul;32(7):884-894.e4. doi: 10.1016/j.echo.2019.03.015. J Am Soc Echocardiogr. 2019. PMID: 31272593 Free PMC article.
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1): study protocol and review of literature.
El-Khuffash A, McNamara PJ, Breatnach C, Bussmann N, Smith A, Feeney O, Tully E, Griffin J, de Boode WP, Cleary B, Franklin O, Dempsey E. El-Khuffash A, et al. Matern Health Neonatol Perinatol. 2018 Dec 3;4:24. doi: 10.1186/s40748-018-0093-1. eCollection 2018. Matern Health Neonatol Perinatol. 2018. PMID: 30524749 Free PMC article. Review.
Introduction to neonatologist-performed echocardiography.
Groves AM, Singh Y, Dempsey E, Molnar Z, Austin T, El-Khuffash A, de Boode WP; European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE). Groves AM, et al. Pediatr Res. 2018 Jul;84(Suppl 1):1-12. doi: 10.1038/s41390-018-0076-y. Pediatr Res. 2018. PMID: 30072808 Free PMC article. Review.
Application of Neonatologist Performed Echocardiography in the assessment and management of persistent pulmonary hypertension of the newborn.
de Boode WP, Singh Y, Molnar Z, Schubert U, Savoia M, Sehgal A, Levy PT, McNamara PJ, El-Khuffash A; European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE). de Boode WP, et al. Pediatr Res. 2018 Jul;84(Suppl 1):68-77. doi: 10.1038/s41390-018-0082-0. Pediatr Res. 2018. PMID: 30072805 Free PMC article. Review.
Application of NPE in the assessment of a patent ductus arteriosus.
van Laere D, van Overmeire B, Gupta S, El-Khuffash A, Savoia M, McNamara PJ, Schwarz CE, de Boode WP; European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE). van Laere D, et al. Pediatr Res. 2018 Jul;84(Suppl 1):46-56. doi: 10.1038/s41390-018-0077-x. Pediatr Res. 2018. PMID: 30072803 Free PMC article. Review.
Application of Neonatologist Performed Echocardiography in the Assessment and Management of Neonatal Heart Failure unrelated to Congenital Heart Disease.
Levy PT, Tissot C, Horsberg Eriksen B, Nestaas E, Rogerson S, McNamara PJ, El-Khuffash A, de Boode WP; European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE). Levy PT, et al. Pediatr Res. 2018 Jul;84(Suppl 1):78-88. doi: 10.1038/s41390-018-0075-z. Pediatr Res. 2018. PMID: 30072802 Free PMC article. Review.
Early career investigator highlight-November.
El-Khuffash AF. El-Khuffash AF. Pediatr Res. 2017 Nov;82(5):722. doi: 10.1038/pr.2017.189. Epub 2017 Sep 13. Pediatr Res. 2017. PMID: 28902186 No abstract available.
Tale of Two Patent Ductus Arteriosus Severity Scores: Similarities and Differences.
Fink D, El-Khuffash A, McNamara PJ, Nitzan I, Hammerman C. Fink D, et al. Am J Perinatol. 2018 Jan;35(1):55-58. doi: 10.1055/s-0037-1605576. Epub 2017 Aug 8. Am J Perinatol. 2018. PMID: 28787748
OBJECTIVE: The objective of this study was to compare the ability of two different scoring systems to evaluate the hemodynamic significance of the PDA and to predict long-term PDA-associated morbidities. SUBJECTS: El-Khuffash cohort (previously described) was derived from …
OBJECTIVE: The objective of this study was to compare the ability of two different scoring systems to evaluate the hemodynamic significance …
Maturational Patterns of Systolic Ventricular Deformation Mechanics by Two-Dimensional Speckle-Tracking Echocardiography in Preterm Infants over the First Year of Age.
Levy PT, El-Khuffash A, Patel MD, Breatnach CR, James AT, Sanchez AA, Abuchabe C, Rogal SR, Holland MR, McNamara PJ, Jain A, Franklin O, Mertens L, Hamvas A, Singh GK. Levy PT, et al. J Am Soc Echocardiogr. 2017 Jul;30(7):685-698.e1. doi: 10.1016/j.echo.2017.03.003. Epub 2017 Apr 19. J Am Soc Echocardiogr. 2017. PMID: 28433214 Free PMC article.
Recommendations for neonatologist performed echocardiography in Europe: Consensus Statement endorsed by European Society for Paediatric Research (ESPR) and European Society for Neonatology (ESN).
de Boode WP, Singh Y, Gupta S, Austin T, Bohlin K, Dempsey E, Groves A, Eriksen BH, van Laere D, Molnar Z, Nestaas E, Rogerson S, Schubert U, Tissot C, van der Lee R, van Overmeire B, El-Khuffash A. de Boode WP, et al. Pediatr Res. 2016 Oct;80(4):465-71. doi: 10.1038/pr.2016.126. Epub 2016 Jun 8. Pediatr Res. 2016. PMID: 27384404 Free PMC article. No abstract available.
Catecholamine-resistant hypotension and myocardial performance following patent ductus arteriosus ligation.
Noori S, McNamara P, Jain A, Lavoie PM, Wickremasinghe A, Merritt TA, Solomon T, Sekar K, Attridge JT, Swanson JR, Gillam-Krakauer M, Reese J, Poindexter BB, Brook M, Auchus RJ, Clyman RI; PDA Ligation/Hypotension Trial Investigators. Noori S, et al. J Perinatol. 2015 Feb;35(2):123-7. doi: 10.1038/jp.2014.151. Epub 2014 Aug 14. J Perinatol. 2015. PMID: 25118721 Free PMC article. Clinical Trial.
Hypotension following patent ductus arteriosus ligation: the role of adrenal hormones.
Clyman RI, Wickremasinghe A, Merritt TA, Solomon T, McNamara P, Jain A, Singh J, Chu A, Noori S, Sekar K, Lavoie PM, Attridge JT, Swanson JR, Gillam-Krakauer M, Reese J, DeMauro S, Poindexter B, Aucott S, Satpute M, Fernandez E, Auchus RJ; Patent Ductus Arteriosus Ligation/Hypotension Trial Investigators. Clyman RI, et al. J Pediatr. 2014 Jun;164(6):1449-55.e1. doi: 10.1016/j.jpeds.2014.01.058. Epub 2014 Mar 15. J Pediatr. 2014. PMID: 24636853 Free PMC article.
The patent ductus arteriosus ligation decision.
El-Khuffash AF, McNamara PJ. El-Khuffash AF, et al. J Pediatr. 2011 Jun;158(6):1037-8; author reply 1038-9. doi: 10.1016/j.jpeds.2010.12.047. Epub 2011 Feb 24. J Pediatr. 2011. PMID: 21349543 No abstract available.
The Use of N-Terminal-Pro-BNP in Preterm Infants.
El-Khuffash A, Molloy E. El-Khuffash A, et al. Int J Pediatr. 2009;2009:175216. doi: 10.1155/2009/175216. Epub 2009 Dec 30. Int J Pediatr. 2009. PMID: 20069108 Free PMC article.
Incidental finding of endocarditis in a preterm neonate.
El-Khuffash A, Molloy EJ. El-Khuffash A, et al. BMJ Case Rep. 2009;2009:bcr2006106625. doi: 10.1136/bcr.2006.106625. Epub 2009 Feb 18. BMJ Case Rep. 2009. PMID: 21687205 Free PMC article. No abstract available.
Serum albumin and mortality in very low birth weight infants.
Morris I, McCallion N, El-Khuffash A, Molloy EJ. Morris I, et al. Arch Dis Child Fetal Neonatal Ed. 2008 Jul;93(4):F310-2. doi: 10.1136/adc.2007.131375. Epub 2008 Jan 24. Arch Dis Child Fetal Neonatal Ed. 2008. PMID: 18218659
Serum troponin in neonatal intensive care.
El-Khuffash AF, Molloy EJ. El-Khuffash AF, et al. Neonatology. 2008;94(1):1-7. doi: 10.1159/000112540. Epub 2007 Dec 19. Neonatology. 2008. PMID: 18097151 Review.
Incidental finding of endocarditis in a preterm neonate.
El-Khuffash A, Molloy EJ. El-Khuffash A, et al. Arch Dis Child Fetal Neonatal Ed. 2007 Mar;92(2):F134. doi: 10.1136/adc.2006.106625. Arch Dis Child Fetal Neonatal Ed. 2007. PMID: 17337660 Free PMC article. No abstract available.