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Kindling and behavioral sensitization: are they relevant to recurrent suicide attempts?
Pettit JW, Joiner TE Jr, Rudd MD. Pettit JW, et al. J Affect Disord. 2004 Dec;83(2-3):249-52. doi: 10.1016/j.jad.2004.08.010. J Affect Disord. 2004. PMID: 15555722
BACKGROUND: Data from a sample of suicidal young adults were used to examine the relevance of the kindling and behavioral sensitization models to suicide attempts. Three predictions derived from the kindling and sensitization models were tested: a high …
BACKGROUND: Data from a sample of suicidal young adults were used to examine the relevance of the kindling and behavioral sens …
Risk-taking behaviors and stressors differentially predict suicidal preparation, non-fatal suicide attempts, and suicide deaths.
Athey A, Overholser J, Bagge C, Dieter L, Vallender E, Stockmeier CA. Athey A, et al. Psychiatry Res. 2018 Dec;270:160-167. doi: 10.1016/j.psychres.2018.09.032. Epub 2018 Sep 15. Psychiatry Res. 2018. PMID: 30253320 Free PMC article.
Negative life events are elevated in suicidal populations. Diathesis-stress and kindling effects models suggest different mechanisms by which negative life events increase suicide risk. ...Stressors may impact risk for fatal suicidal behaviors in mood …
Negative life events are elevated in suicidal populations. Diathesis-stress and kindling effects models suggest different mech …
Repetition of suicide attempts across episodes of severe depression. Behavioural sensitisation found in suicide group but not in controls.
Brådvik L, Berglund M. Brådvik L, et al. BMC Psychiatry. 2011 Jan 7;11:5. doi: 10.1186/1471-244X-11-5. BMC Psychiatry. 2011. PMID: 21214896 Free PMC article.
A behavioural sensitisation or kindling model has been proposed for suicidal behaviour, in accordance with a sensitisation model of depressive episodes. ...The occurrence of initial and repeated suicide attempts by order of the depressive episodes was compare …
A behavioural sensitisation or kindling model has been proposed for suicidal behaviour, in accordance with a sensitisation mod …
Influence of carbamazepine on kindling grades in depressive and non-depressive rats.
Barbakadze M, Bilanishvili I, Chkhetiani M, Khizanishvili N, Koreli A. Barbakadze M, et al. Georgian Med News. 2010 May;(182):68-71. Georgian Med News. 2010. PMID: 20587836
On the other hand, some anti-epileptic drugs were found to aggravate depressive state, even to a suicide outcome. Bearing in mind these findings, we endeavored an experimental study in the laboratory rats, 25% of which display an inborn depressive behavior. An anti-epilept …
On the other hand, some anti-epileptic drugs were found to aggravate depressive state, even to a suicide outcome. Bearing in mind the …
Epigenetic basis of sensitization to stress, affective episodes, and stimulants: implications for illness progression and prevention.
Post RM. Post RM. Bipolar Disord. 2016 Jun;18(4):315-24. doi: 10.1111/bdi.12401. Bipolar Disord. 2016. PMID: 27346321 Review.
Sensitization processes are remediable or preventable risk factors for a poor illness outcome and deserve increased clinical, public health, and research attention in the hopes of making the recurrent unipolar and bipolar affective disorders less impairing, disabling, and lethal …
Sensitization processes are remediable or preventable risk factors for a poor illness outcome and deserve increased clinical, public health, …
Negative experiences in childhood and the development and course of bipolar disorder.
Jaworska-Andryszewska P, Rybakowski J. Jaworska-Andryszewska P, et al. Psychiatr Pol. 2016 Oct 31;50(5):989-1000. doi: 10.12740/PP/61159. Psychiatr Pol. 2016. PMID: 27992891 Free article. Review. English, Polish.
The negative childhood experiences that may play a role in BD are critical or traumatic events including all kinds of abuse, loss of a parent or parents resulting from death, suicide, separation, divorce or prolonged separation. ...In BD patients these events are associate …
The negative childhood experiences that may play a role in BD are critical or traumatic events including all kinds of abuse, loss of a paren …
Comparative bioethics in bipolar and epilepsy research.
Kaufman KR. Kaufman KR. Seizure. 2002 Jan;11(1):51-6. doi: 10.1053/seiz.2001.0585. Seizure. 2002. PMID: 11888261 Free article. Review.
Bipolar depression has a significant risk for suicide; bipolar episodes can lead to kindling with increased long-term morbidity; rapid regression may occur during the placebo phase or during dose ranging trials with resultant active suicide status. ...The aut …
Bipolar depression has a significant risk for suicide; bipolar episodes can lead to kindling with increased long-term morbidit …
Clinical consequences of sensitisation in affective disorder: a case register study.
Kessing LV, Mortensen PB, Bolwig TG. Kessing LV, et al. J Affect Disord. 1998 Jan;47(1-3):41-7. doi: 10.1016/s0165-0327(97)00128-6. J Affect Disord. 1998. PMID: 9476742
The predictive effect of measures of the initial course of episodes was investigated in relation to the subsequent risk of alcoholism, dementia, death and suicidal attempts/suicide in a case register study including all hospital admissions with primary affective dis …
The predictive effect of measures of the initial course of episodes was investigated in relation to the subsequent risk of alcoholism, demen …
Lithium treatment present and future.
Gomez GE. Gomez GE. J Psychosoc Nurs Ment Health Serv. 2001 Aug;39(8):31-7. J Psychosoc Nurs Ment Health Serv. 2001. PMID: 11503429
Recent studies suggest that long-term lithium treatment may have mortality-lowering and anti-suicidal effects. 4. Chronic lithium, or valproate, administration has been shown to have a neuroprotective effect on rat and human cultured neurons....
Recent studies suggest that long-term lithium treatment may have mortality-lowering and anti-suicidal effects. 4. Chronic lithium, or …
[Reconstruction of a suicide by a homemade firearm].
Maxeiner H, Horn W, Beyer W, Mittelhaube V. Maxeiner H, et al. Arch Kriminol. 1986 Jan-Feb;177(1-2):19-28. Arch Kriminol. 1986. PMID: 3963990 German.
He pluged one end of a waterpipe, used a cylindrical lead shot (Cal. 1.2 cm, length 2.15 cm, mass 22.7 g), special black powder (about 4 g, from fire-crackers; powder with an admixture of aluminium) and kindled the weapon in front of his chest by a slowmatch. ...
He pluged one end of a waterpipe, used a cylindrical lead shot (Cal. 1.2 cm, length 2.15 cm, mass 22.7 g), special black powder (about 4 g, …
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