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79 results

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Page 1
Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.
Sasmita AO, Depp C, Nazarenko T, Sun T, Siems SB, Ong EC, Nkeh YB, Böhler C, Yu X, Bues B, Evangelista L, Mao S, Morgado B, Wu Z, Ruhwedel T, Subramanian S, Börensen F, Overhoff K, Spieth L, Berghoff SA, Sadleir KR, Vassar R, Eggert S, Goebbels S, Saito T, Saido T, Saher G, Möbius W, Castelo-Branco G, Klafki HW, Wirths O, Wiltfang J, Jäkel S, Yan R, Nave KA. Sasmita AO, et al. Among authors: klafki hw. Nat Neurosci. 2024 Sep;27(9):1668-1674. doi: 10.1038/s41593-024-01730-3. Epub 2024 Aug 5. Nat Neurosci. 2024. PMID: 39103558 Free PMC article.
Phosphorylated tau 181 and 217 are elevated in serum and muscle of patients with amyotrophic lateral sclerosis.
Abu-Rumeileh S, Scholle L, Mensch A, Großkopf H, Ratti A, Kölsch A, Stoltenburg-Didinger G, Conrad J, De Gobbi A, Barba L, Steinacker P, Klafki HW, Oeckl P, Halbgebauer S, Stapf C, Posa A, Kendzierski T, Silani V, Hausner L, Ticozzi N, Froelich L, Weishaupt JH, Verde F, Otto M. Abu-Rumeileh S, et al. Among authors: klafki hw. Nat Commun. 2025 Mar 5;16(1):2019. doi: 10.1038/s41467-025-57144-7. Nat Commun. 2025. PMID: 40044663 Free PMC article.
Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.
Vogelgsang J, Hansen N, Stark M, Wagner M, Klafki H, Morgado BM, Jahn-Brodmann A, Schott B, Esselmann H, Bauer C, Schuchhardt J, Kleineidam L, Wolfsgruber S, Peters O, Schneider LS, Wang X, Menne F, Priller J, Spruth E, Altenstein S, Lohse A, Schneider A, Fliessbach K, Vogt I, Bartels C, Jessen F, Rostamzadeh A, Duezel E, Glanz W, Incesoy E, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann B, Guersel S, Teipel S, Kilimann I, Goerss D, Laske C, Munk M, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka M, Brosseron F, Ramierez A, Schmid M, Wiltfang J. Vogelgsang J, et al. Among authors: klafki h. Alzheimers Dement. 2024 Aug;20(8):5132-5142. doi: 10.1002/alz.13909. Epub 2024 Jun 28. Alzheimers Dement. 2024. PMID: 38940303 Free PMC article.
Disease tracking markers for Alzheimer's disease at the prodromal (MCI) stage.
Drago V, Babiloni C, Bartrés-Faz D, Caroli A, Bosch B, Hensch T, Didic M, Klafki HW, Pievani M, Jovicich J, Venturi L, Spitzer P, Vecchio F, Schoenknecht P, Wiltfang J, Redolfi A, Forloni G, Blin O, Irving E, Davis C, Hårdemark HG, Frisoni GB. Drago V, et al. Among authors: klafki hw. J Alzheimers Dis. 2011;26 Suppl 3:159-99. doi: 10.3233/JAD-2011-0043. J Alzheimers Dis. 2011. PMID: 21971460 Review.
Therapeutic approaches to Alzheimer's disease.
Klafki HW, Staufenbiel M, Kornhuber J, Wiltfang J. Klafki HW, et al. Brain. 2006 Nov;129(Pt 11):2840-55. doi: 10.1093/brain/awl280. Epub 2006 Oct 3. Brain. 2006. PMID: 17018549 Review.
Amino-terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains.
Wirths O, Lehnen C, Fricke M, Talucci I, Klafki HW, Morgado B, Lehmann S, Münch C, Liepold T, Wiltfang J, Rostagno A, Ghiso J, Maric HM, Jahn O, Weggen S. Wirths O, et al. Among authors: klafki hw. Neuropathol Appl Neurobiol. 2024 Jun;50(3):e12991. doi: 10.1111/nan.12991. Neuropathol Appl Neurobiol. 2024. PMID: 38867123
79 results