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Page 1
Clinical review: Klinefelter syndrome--a clinical update.
Groth KA, Skakkebæk A, Høst C, Gravholt CH, Bojesen A. Groth KA, et al. J Clin Endocrinol Metab. 2013 Jan;98(1):20-30. doi: 10.1210/jc.2012-2382. Epub 2012 Nov 1. J Clin Endocrinol Metab. 2013. PMID: 23118429 Review.
CONTEXT: Recently, new clinically important information regarding Klinefelter syndrome (KS) has been published. ...Medical treatment is mainly testosterone replacement therapy to alleviate acute and long-term consequences of hypogonadism as well …
CONTEXT: Recently, new clinically important information regarding Klinefelter syndrome (KS) has been published. ...Medi …
Klinefelter's syndrome.
Lanfranco F, Kamischke A, Zitzmann M, Nieschlag E. Lanfranco F, et al. Lancet. 2004 Jul 17-23;364(9430):273-83. doi: 10.1016/S0140-6736(04)16678-6. Lancet. 2004. PMID: 15262106 Review.
Klinefelter's syndrome is the most common genetic cause of human male infertility, but many cases remain undiagnosed because of substantial variation in clinical presentation and insufficient professional awareness of the syndrome itself. …
Klinefelter's syndrome is the most common genetic cause of human male infertility, but many cases remain undiagn …
Klinefelter Syndrome.
Los E, Leslie SW, Ford GA. Los E, et al. 2023 Nov 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Nov 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29493939 Free Books & Documents.
Klinefelter syndrome (KS) results from 2 or more X chromosomes in a phenotypic male. The clinical phenotype of KS was first described by American physician Dr. ...A similar but much less common condition, Jacobs syndrome, has the genotype 47,XYY …
Klinefelter syndrome (KS) results from 2 or more X chromosomes in a phenotypic male. The clinical phenotype of K …
Klinefelter syndrome: etiology and clinical considerations in male infertility.
Chen X, Zhang X, Jiang T, Xu W. Chen X, et al. Biol Reprod. 2024 Sep 14;111(3):516-528. doi: 10.1093/biolre/ioae076. Biol Reprod. 2024. PMID: 38785325 Review.
Klinefelter syndrome (KS) is the most prevalent chromosomal disorder occurring in males. ...A major phenotype is impaired reproductive function, in the form of low testosterone and infertility. This review comprehensively examines the genetic and physiologica …
Klinefelter syndrome (KS) is the most prevalent chromosomal disorder occurring in males. ...A major phenotype is impaired repr …
The Klinefelter Syndrome and Testicular Sperm Retrieval Outcomes.
Sá R, Ferraz L, Barros A, Sousa M. Sá R, et al. Genes (Basel). 2023 Mar 4;14(3):647. doi: 10.3390/genes14030647. Genes (Basel). 2023. PMID: 36980920 Free PMC article. Review.
Klinefelter syndrome (KS), caused by the presence of an extra X chromosome, is the most prevalent chromosomal sexual anomaly, with an estimated incidence of 1:500/1000 per male live birth (karyotype 47,XXY). ...The retrieval of spermatozoa from the testicles …
Klinefelter syndrome (KS), caused by the presence of an extra X chromosome, is the most prevalent chromosomal sexual anomaly, …
Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells.
Zhao L, Yao C, Xing X, Jing T, Li P, Zhu Z, Yang C, Zhai J, Tian R, Chen H, Luo J, Liu N, Deng Z, Lin X, Li N, Fang J, Sun J, Wang C, Zhou Z, Li Z. Zhao L, et al. Nat Commun. 2020 Nov 10;11(1):5683. doi: 10.1038/s41467-020-19414-4. Nat Commun. 2020. PMID: 33173058 Free PMC article.
Clinical efficacy of treatments against non-obstructive azoospermia (NOA), which affects 1% of men, are currently limited by the incomplete understanding of NOA pathogenesis and normal spermatogenic microenvironment. ...Notably, Sertoli cells of patients with congen …
Clinical efficacy of treatments against non-obstructive azoospermia (NOA), which affects 1% of men, are currently limited by t …
Gonadotropin-Releasing Hormone Receptor (GnRHR) and Hypogonadotropic Hypogonadism.
Fanis P, Neocleous V, Papapetrou I, Phylactou LA, Skordis N. Fanis P, et al. Int J Mol Sci. 2023 Nov 4;24(21):15965. doi: 10.3390/ijms242115965. Int J Mol Sci. 2023. PMID: 37958948 Free PMC article. Review.
Such mutations in the GNRHR are linked to normosmic hypogonadotropic hypogonadism and lead to various clinical symptoms, including delayed puberty, infertility, and impaired sexual development. ...This comprehensive review explores GnRHR's multifaceted role in human …
Such mutations in the GNRHR are linked to normosmic hypogonadotropic hypogonadism and lead to various clinical symptoms, including de …
In vitro spermatogenesis in artificial testis: current knowledge and clinical implications for male infertility.
Bashiri Z, Gholipourmalekabadi M, Khadivi F, Salem M, Afzali A, Cham TC, Koruji M. Bashiri Z, et al. Cell Tissue Res. 2023 Dec;394(3):393-421. doi: 10.1007/s00441-023-03824-z. Epub 2023 Sep 18. Cell Tissue Res. 2023. PMID: 37721632 Review.
Therefore, new advances in stem cell research may lead to promising therapies for treating male infertility. The rate of progression and breakthrough in the area of in vitro spermatogenesis is lower than that of SSC transplantation, but newer methods are also being …
Therefore, new advances in stem cell research may lead to promising therapies for treating male infertility. The rate of progr …
Klinefelter Syndrome and medical treatment: hypogonadism and beyond.
Chang S, Skakkebæk A, Gravholt CH. Chang S, et al. Hormones (Athens). 2015 Oct-Dec;14(4):531-48. doi: 10.14310/horm.2002.1622. Hormones (Athens). 2015. PMID: 26732150 Free article. Review.
Klinefelter syndrome (KS), though described more than 70 years ago, still imposes significant diagnostic challenges. ...The mainstay of medical treatment is testosterone replacement therapy to both attenuate acute and long-term consequences of hypogona …
Klinefelter syndrome (KS), though described more than 70 years ago, still imposes significant diagnostic challenges. ...The ma …
Klinefelter syndrome in clinical practice.
Bojesen A, Gravholt CH. Bojesen A, et al. Nat Clin Pract Urol. 2007 Apr;4(4):192-204. doi: 10.1038/ncpuro0775. Nat Clin Pract Urol. 2007. PMID: 17415352 Review.
Klinefelter syndrome is the most common sex-chromosome disorder; it affects approximately one in every 660 men. ...Patients with Klinefelter syndrome should be treated with lifelong testosterone supplementation that begins at puberty, to secure proper …
Klinefelter syndrome is the most common sex-chromosome disorder; it affects approximately one in every 660 men. ...Patients wi …
197 results