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Year Number of Results
2003 3
2005 2
2006 1
2007 1
2008 1
2009 4
2010 3
2011 4
2012 4
2013 4
2014 1
2015 3
2016 4
2017 6
2018 4
2019 3
2020 3
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47 results
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Animal models of α-synucleinopathy for Parkinson disease drug development.
Koprich JB, Kalia LV, Brotchie JM. Koprich JB, et al. Nat Rev Neurosci. 2017 Sep;18(9):515-529. doi: 10.1038/nrn.2017.75. Epub 2017 Jul 13. Nat Rev Neurosci. 2017. PMID: 28747776 Review.
α-Synuclein-Based Animal Models of Parkinson's Disease: Challenges and Opportunities in a New Era.
Visanji NP, Brotchie JM, Kalia LV, Koprich JB, Tandon A, Watts JC, Lang AE. Visanji NP, et al. Among authors: koprich jb. Trends Neurosci. 2016 Nov;39(11):750-762. doi: 10.1016/j.tins.2016.09.003. Epub 2016 Oct 21. Trends Neurosci. 2016. PMID: 27776749 Review.
A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia.
Henrich MT, Geibl FF, Lee B, Chiu WH, Koprich JB, Brotchie JM, Timmermann L, Decher N, Matschke LA, Oertel WH. Henrich MT, et al. Among authors: koprich jb. Acta Neuropathol Commun. 2018 May 10;6(1):39. doi: 10.1186/s40478-018-0541-1. Acta Neuropathol Commun. 2018. PMID: 29747690 Free PMC article.
AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.
Ip CW, Klaus LC, Karikari AA, Visanji NP, Brotchie JM, Lang AE, Volkmann J, Koprich JB. Ip CW, et al. Among authors: koprich jb. Acta Neuropathol Commun. 2017 Feb 1;5(1):11. doi: 10.1186/s40478-017-0416-x. Acta Neuropathol Commun. 2017. PMID: 28143577 Free PMC article.
GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson's Disease.
Schneider JS, Aras R, Williams CK, Koprich JB, Brotchie JM, Singh V. Schneider JS, et al. Among authors: koprich jb. Sci Rep. 2019 Jun 10;9(1):8362. doi: 10.1038/s41598-019-42847-x. Sci Rep. 2019. PMID: 31182727 Free PMC article.
Subthalamic nucleus deep brain stimulation is neuroprotective in the A53T α-synuclein Parkinson's disease rat model.
Musacchio T, Rebenstorff M, Fluri F, Brotchie JM, Volkmann J, Koprich JB, Ip CW. Musacchio T, et al. Among authors: koprich jb. Ann Neurol. 2017 Jun;81(6):825-836. doi: 10.1002/ana.24947. Epub 2017 Jun 9. Ann Neurol. 2017. PMID: 28470693 Free PMC article.
Update on Molecular Imaging in Parkinson's Disease.
Liu ZY, Liu FT, Zuo CT, Koprich JB, Wang J. Liu ZY, et al. Among authors: koprich jb. Neurosci Bull. 2018 Apr;34(2):330-340. doi: 10.1007/s12264-017-0202-6. Epub 2017 Dec 27. Neurosci Bull. 2018. PMID: 29282614 Free PMC article. Review.
Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism.
Gleave JA, Arathoon LR, Trinh D, Lizal KE, Giguère N, Barber JHM, Najarali Z, Khan MH, Thiele SL, Semmen MS, Koprich JB, Brotchie JM, Eubanks JH, Trudeau LE, Nash JE. Gleave JA, et al. Among authors: koprich jb. Neurobiol Dis. 2017 Oct;106:133-146. doi: 10.1016/j.nbd.2017.06.009. Epub 2017 Jul 1. Neurobiol Dis. 2017. PMID: 28673739
Non-steric-zipper models for pathogenic α-synuclein conformers.
Schuman B, Won A, Brand-Arzamendi K, Koprich JB, Wen XY, Howson PA, Brotchie JM, Yip CM. Schuman B, et al. Among authors: koprich jb. APL Bioeng. 2018 May 1;2(2):026105. doi: 10.1063/1.5023460. eCollection 2018 Jun. APL Bioeng. 2018. PMID: 31069302 Free PMC article.
Generation and Analysis of Viral Vector-Mediated Rodent Models for Parkinson's Disease.
Karikari AA, Koprich JB, Ip CW. Karikari AA, et al. Among authors: koprich jb. Methods Mol Biol. 2019;1948:271-286. doi: 10.1007/978-1-4939-9124-2_21. Methods Mol Biol. 2019. PMID: 30771185
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