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Metabolic stress-induced inflammation plays a major role in the development of osteoarthritis in mice.

Gierman LM, van der Ham F, Koudijs A, Wielinga PY, Kleemann R, Kooistra T, Stoop R, Kloppenburg M, van Osch GJ, Stojanovic-Susulic V, Huizinga TW, Zuurmond AM. Gierman LM, et al. Among authors: koudijs a. Arthritis Rheum. 2012 Apr;64(4):1172-81. doi: 10.1002/art.33443. Epub 2011 Oct 27. Arthritis Rheum. 2012. PMID: 22034049 Free article.

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Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice--a translational model for atherosclerosis.

Gierman LM, Kühnast S, Koudijs A, Pieterman EJ, Kloppenburg M, van Osch GJ, Stojanovic-Susulic V, Huizinga TW, Princen HM, Zuurmond AM. Gierman LM, et al. Among authors: koudijs a. Ann Rheum Dis. 2014 May;73(5):921-7. doi: 10.1136/annrheumdis-2013-203248. Epub 2013 Apr 26. Ann Rheum Dis. 2014. PMID: 23625977

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EPH receptor B2 stimulates human monocyte adhesion and migration independently of its EphrinB ligands.

Vreeken D, Bruikman CS, Cox SML, Zhang H, Lalai R, Koudijs A, van Zonneveld AJ, Hovingh GK, van Gils JM. Vreeken D, et al. Among authors: koudijs a. J Leukoc Biol. 2020 Sep;108(3):999-1011. doi: 10.1002/JLB.2A0320-283RR. Epub 2020 Apr 26. J Leukoc Biol. 2020. PMID: 32337793 Free PMC article.

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Integration of efficacy, pharmacokinetic and safety assessment of interleukin-1 receptor antagonist in a preclinical model of arthritis.

Zuurmond AM, Koudijs A, van El B, Doornbos RP, van Manen-Vernooij BC, Bastiaans JH, Penninks AH, van Bilsen JH, Cnubben NH, Degroot J. Zuurmond AM, et al. Among authors: koudijs a. Regul Toxicol Pharmacol. 2011 Apr;59(3):461-70. doi: 10.1016/j.yrtph.2011.01.014. Epub 2011 Feb 12. Regul Toxicol Pharmacol. 2011. PMID: 21300126

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Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy.

Boels MG, Avramut MC, Koudijs A, Dane MJ, Lee DH, van der Vlag J, Koster AJ, van Zonneveld AJ, van Faassen E, Gröne HJ, van den Berg BM, Rabelink TJ. Boels MG, et al. Among authors: koudijs a. Diabetes. 2016 Aug;65(8):2429-39. doi: 10.2337/db15-1413. Epub 2016 Mar 25. Diabetes. 2016. PMID: 27207530

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In Vivo Assessment of Size-Selective Glomerular Sieving in Transplanted Human Induced Pluripotent Stem Cell-Derived Kidney Organoids.

van den Berg CW, Koudijs A, Ritsma L, Rabelink TJ. van den Berg CW, et al. Among authors: koudijs a. J Am Soc Nephrol. 2020 May;31(5):921-929. doi: 10.1681/ASN.2019060573. J Am Soc Nephrol. 2020. PMID: 32354986 Free PMC article.

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Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis.

Bijkerk R, Au YW, Stam W, Duijs JMGJ, Koudijs A, Lievers E, Rabelink TJ, van Zonneveld AJ. Bijkerk R, et al. Among authors: koudijs a. Front Pharmacol. 2019 Mar 11;10:215. doi: 10.3389/fphar.2019.00215. eCollection 2019. Front Pharmacol. 2019. PMID: 30914951 Free PMC article.

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Profiling the secretion of soluble mediators by end stage osteoarthritis synovial tissue explants reveals a reduced responsiveness to an inflammatory trigger.

Gierman LM, van El B, van der Ham F, Koudijs A, Stoop R, Verheijen JH, Kloppenburg M, van Osch GJ, Stojanovic-Susulic V, Huizinga TW, Zuurmond AM. Gierman LM, et al. Among authors: koudijs a. PLoS One. 2013 May 3;8(5):e62634. doi: 10.1371/journal.pone.0062634. Print 2013. PLoS One. 2013. PMID: 23658758 Free PMC article.

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Properdin binds independent of complement activation in an in vivo model of anti-glomerular basement membrane disease.

O'Flynn J, Kotimaa J, Faber-Krol R, Koekkoek K, Klar-Mohamad N, Koudijs A, Schwaeble WJ, Stover C, Daha MR, van Kooten C. O'Flynn J, et al. Among authors: koudijs a. Kidney Int. 2018 Dec;94(6):1141-1150. doi: 10.1016/j.kint.2018.06.030. Epub 2018 Oct 12. Kidney Int. 2018. PMID: 30322716

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Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy.

Boels MGS, Koudijs A, Avramut MC, Sol WMPJ, Wang G, van Oeveren-Rietdijk AM, van Zonneveld AJ, de Boer HC, van der Vlag J, van Kooten C, Eulberg D, van den Berg BM, IJpelaar DHT, Rabelink TJ. Boels MGS, et al. Among authors: koudijs a. Am J Pathol. 2017 Nov;187(11):2430-2440. doi: 10.1016/j.ajpath.2017.07.020. Epub 2017 Aug 22. Am J Pathol. 2017. PMID: 28837800 Free article.

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