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The pharmacology and toxicology of kratom: from traditional herb to drug of abuse.
Warner ML, Kaufman NC, Grundmann O. Warner ML, et al. Int J Legal Med. 2016 Jan;130(1):127-38. doi: 10.1007/s00414-015-1279-y. Epub 2015 Oct 28. Int J Legal Med. 2016. PMID: 26511390 Review.
Mitragyna speciosa (Rubiaceae), commonly known as kratom, is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. In recent years, kratom has gained popularity for use as a recreational drug across the globe. ...
Mitragyna speciosa (Rubiaceae), commonly known as kratom, is a tropical tree with a long history of traditional use in parts o …
Traditional and non-traditional uses of Mitragynine (Kratom): A survey of the literature.
Singh D, Narayanan S, Vicknasingam B. Singh D, et al. Brain Res Bull. 2016 Sep;126(Pt 1):41-46. doi: 10.1016/j.brainresbull.2016.05.004. Epub 2016 May 10. Brain Res Bull. 2016. PMID: 27178014 Review.
INTRODUCTION: The objective of the paper was to highlight the differences in the traditional and non-traditional users of kratom in the South East Asian and Western contexts. METHOD: A literature survey of published kratom studies among humans was conducted. ...More …
INTRODUCTION: The objective of the paper was to highlight the differences in the traditional and non-traditional users of kratom in t …
Neurobiology of Kratom and its main alkaloid mitragynine.
Suhaimi FW, Yusoff NH, Hassan R, Mansor SM, Navaratnam V, Müller CP, Hassan Z. Suhaimi FW, et al. Brain Res Bull. 2016 Sep;126(Pt 1):29-40. doi: 10.1016/j.brainresbull.2016.03.015. Epub 2016 Mar 25. Brain Res Bull. 2016. PMID: 27018165 Review.
Kratom or its main alkaloid, mitragynine is derived from the plant Mitragyna speciosa Korth which is indigenous to Southeast Asian countries. ...
Kratom or its main alkaloid, mitragynine is derived from the plant Mitragyna speciosa Korth which is indigenous to Southeast A …
New drugs of abuse.
Rech MA, Donahey E, Cappiello Dziedzic JM, Oh L, Greenhalgh E. Rech MA, et al. Pharmacotherapy. 2015 Feb;35(2):189-97. doi: 10.1002/phar.1522. Epub 2014 Dec 4. Pharmacotherapy. 2015. PMID: 25471045 Review.
In this article, we describe the clinical and adverse effects and purported pharmacology of several new classes of drugs of abuse including synthetic cannabinoids, synthetic cathinones, salvia, desomorphine, and kratom. Because many of these substances can have severe or l …
In this article, we describe the clinical and adverse effects and purported pharmacology of several new classes of drugs of abuse including …
Hepatotoxicity Induced by "the 3Ks": Kava, Kratom and Khat.
Pantano F, Tittarelli R, Mannocchi G, Zaami S, Ricci S, Giorgetti R, Terranova D, Busardò FP, Marinelli E. Pantano F, et al. Int J Mol Sci. 2016 Apr 16;17(4):580. doi: 10.3390/ijms17040580. Int J Mol Sci. 2016. PMID: 27092496 Free PMC article. Review.
The 3Ks (kava, kratom and khat) are herbals that can potentially induce liver injuries. ...Chronic recreational use of kratom has been associated with rare instances of acute liver injury. ...
The 3Ks (kava, kratom and khat) are herbals that can potentially induce liver injuries. ...Chronic recreational use of kratom …
Herbal Highs: Review on Psychoactive Effects and Neuropharmacology.
Graziano S, Orsolini L, Rotolo MC, Tittarelli R, Schifano F, Pichini S. Graziano S, et al. Curr Neuropharmacol. 2017;15(5):750-761. doi: 10.2174/1570159X14666161031144427. Curr Neuropharmacol. 2017. PMID: 27799032 Free PMC article. Review.
OBJECTIVE: We reviewed psychoactive effects and neuropharmacology of the most used "herbal highs" with characterized active principles, with studies reporting mechanisms of action, pharmacological and subjective effects, eventual secondary effects including intoxications and/or f …
OBJECTIVE: We reviewed psychoactive effects and neuropharmacology of the most used "herbal highs" with characterized active principles, with …
Herbal Supplements and Hepatotoxicity: A Short Review.
Haslan H, Suhaimi FH, Das S. Haslan H, et al. Nat Prod Commun. 2015 Oct;10(10):1779-84. Nat Prod Commun. 2015. PMID: 26669124 Review.
The present review focusses on a few herbs such as Aloe barbadensis, Atractylis gummifera, Centella asiatica, Mitragyna speciosa, Morinda citrifolia, Larea tridentata, Symphytum officinale, Teucrium chamaedrys and Xanthium strumarium, which are reported to cause hepatotoxi …
The present review focusses on a few herbs such as Aloe barbadensis, Atractylis gummifera, Centella asiatica, Mitragyna speciosa, Mor …
Changing trends in the use of kratom (Mitragyna speciosa) in Southeast Asia.
Singh D, Narayanan S, Vicknasingam B, Corazza O, Santacroce R, Roman-Urrestarazu A. Singh D, et al. Hum Psychopharmacol. 2017 May;32(3). doi: 10.1002/hup.2582. Epub 2017 May 24. Hum Psychopharmacol. 2017. PMID: 28544011 Review.
OBJECTIVE: Kratom (Mitragyna speciosa. Korth) is an indigenous medicinal plant of Southeast Asia. ...Two recent trends have also emerged: (a) Kratom is reportedly being used to ease withdrawal from opioid dependence in rural settings; whereas (b) in urban are …
OBJECTIVE: Kratom (Mitragyna speciosa. Korth) is an indigenous medicinal plant of Southeast Asia. ...Two recent trends have al …
From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction.
Hassan Z, Muzaimi M, Navaratnam V, Yusoff NH, Suhaimi FW, Vadivelu R, Vicknasingam BK, Amato D, von Hörsten S, Ismail NI, Jayabalan N, Hazim AI, Mansor SM, Müller CP. Hassan Z, et al. Neurosci Biobehav Rev. 2013 Feb;37(2):138-51. doi: 10.1016/j.neubiorev.2012.11.012. Epub 2012 Dec 1. Neurosci Biobehav Rev. 2013. PMID: 23206666 Review.
Kratom (or Ketum) is a psychoactive plant preparation used in Southeast Asia. It is derived from the plant Mitragyna speciosa Korth. Kratom as well as its main alkaloid, mitragynine, currently spreads around the world. ...
Kratom (or Ketum) is a psychoactive plant preparation used in Southeast Asia. It is derived from the plant Mitragyna speciosa …
The medicinal chemistry and neuropharmacology of kratom: A preliminary discussion of a promising medicinal plant and analysis of its potential for abuse.
Kruegel AC, Grundmann O. Kruegel AC, et al. Neuropharmacology. 2018 May 15;134(Pt A):108-120. doi: 10.1016/j.neuropharm.2017.08.026. Epub 2017 Aug 19. Neuropharmacology. 2018. PMID: 28830758 Review.
The leaves of Mitragyna speciosa (commonly known as kratom), a tree endogenous to parts of Southeast Asia, have been used traditionally for their stimulant, mood-elevating, and analgesic effects and have recently attracted significant attention due to increased use …
The leaves of Mitragyna speciosa (commonly known as kratom), a tree endogenous to parts of Southeast Asia, have been used trad …
19 results