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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1916 2
1917 3
1924 1
1925 3
1928 2
1929 1
1930 6
1931 1
1932 2
1934 1
1935 1
1937 1
1938 2
1939 1
1940 4
1941 1
1942 2
1943 1
1944 2
1945 6
1946 16
1947 10
1948 21
1949 9
1950 16
1951 34
1952 46
1953 58
1954 53
1955 63
1956 103
1957 123
1958 105
1959 104
1960 123
1961 132
1962 160
1963 293
1964 449
1965 310
1966 299
1967 367
1968 451
1969 575
1970 548
1971 690
1972 680
1973 626
1974 738
1975 870
1976 785
1977 833
1978 779
1979 819
1980 942
1981 915
1982 1051
1983 1119
1984 1211
1985 1278
1986 1462
1987 1310
1988 1462
1989 1610
1990 1826
1991 2097
1992 2687
1993 2972
1994 3471
1995 3721
1996 3716
1997 3965
1998 3968
1999 3889
2000 3916
2001 3688
2002 3773
2003 3806
2004 3894
2005 4068
2006 4177
2007 4252
2008 4101
2009 3977
2010 4032
2011 4152
2012 4135
2013 4145
2014 4005
2015 3906
2016 3798
2017 3744
2018 3731
2019 3816
2020 3794
2021 1256
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131,148 results
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Page 1
The pharmacodynamics of L-arginine.
Böger RH. Böger RH. Altern Ther Health Med. 2014 May-Jun;20(3):48-54. Altern Ther Health Med. 2014. PMID: 24755570 Review.
However, in other trials, L-arginine was not beneficial, and in a recent study, the authors reported higher mortality for participants receiving L-arginine than for those receiving placebo. ...L-Arginine appears to exert no effect in indi …
However, in other trials, L-arginine was not beneficial, and in a recent study, the authors reported higher mortality for part …
L-arginine as dietary supplement for improving microvascular function.
Melik Z, Zaletel P, Virtic T, Cankar K. Melik Z, et al. Clin Hemorheol Microcirc. 2017;65(3):205-217. doi: 10.3233/CH-16159. Clin Hemorheol Microcirc. 2017. PMID: 27814280
OBJECTIVE: The aim of the present study was to determine whether the dietary supplement L-arginine improves the endothelial function of microvessels by increasing nitric oxide production. ...CONCLUSION: Obtained results demonstrated that a single dose of L- …
OBJECTIVE: The aim of the present study was to determine whether the dietary supplement L-arginine improves the endothelial fu …
The effects on plasma L-arginine levels of combined oral L-citrulline and L-arginine supplementation in healthy males.
Suzuki T, Morita M, Hayashi T, Kamimura A. Suzuki T, et al. Biosci Biotechnol Biochem. 2017 Feb;81(2):372-375. doi: 10.1080/09168451.2016.1230007. Epub 2016 Sep 26. Biosci Biotechnol Biochem. 2017. PMID: 27667025 Clinical Trial.
We investigated the effects of combining 1 g of l-citrulline and 1 g of l-arginine as oral supplementation on plasma l-arginine levels in healthy males. Oral l-citrulline plus l-arginine supplementation more efficiently incr …
We investigated the effects of combining 1 g of l-citrulline and 1 g of l-arginine as oral supplementation on plasma …
The effect of l-arginine supplementation on lipid profile: a systematic review and meta-analysis of randomised controlled trials.
Hadi A, Arab A, Moradi S, Pantovic A, Clark CCT, Ghaedi E. Hadi A, et al. Br J Nutr. 2019 Nov 14;122(9):1021-1032. doi: 10.1017/S0007114519001855. Br J Nutr. 2019. PMID: 31922465
A number of clinical trials have examined the effect of l-arginine on lipid profile in recent years; however, the results remain equivocal. ...To estimate the overall effect of l-arginine supplementation, we used the random-effects model. In total, twe …
A number of clinical trials have examined the effect of l-arginine on lipid profile in recent years; however, the results rema …
L-Arginine and its metabolites in kidney and cardiovascular disease.
Popolo A, Adesso S, Pinto A, Autore G, Marzocco S. Popolo A, et al. Amino Acids. 2014 Oct;46(10):2271-86. doi: 10.1007/s00726-014-1825-9. Epub 2014 Aug 27. Amino Acids. 2014. PMID: 25161088 Review.
L-Arginine and its metabolites may constitute both a marker of pathology progression both the rationale for manipulating L-arginine metabolism as a strategy to ameliorate these disease. ...This review will discuss the implication of the mains L-
L-Arginine and its metabolites may constitute both a marker of pathology progression both the rationale for manipulating L
Safety and Effectiveness of Arginine in Adults.
McNeal CJ, Meininger CJ, Reddy D, Wilborn CD, Wu G. McNeal CJ, et al. J Nutr. 2016 Dec;146(12):2587S-2593S. doi: 10.3945/jn.116.234740. Epub 2016 Nov 9. J Nutr. 2016. PMID: 27934649 Review.
l-Arginine (Arg) appears to have a beneficial effect on the regulation of nutrient metabolism to enhance lean tissue deposition and on insulin resistance in humans. ...
l-Arginine (Arg) appears to have a beneficial effect on the regulation of nutrient metabolism to enhance lean tissue depositio
L-arginine and cardiovascular system.
Cylwik D, Mogielnicki A, Buczko W. Cylwik D, et al. Pharmacol Rep. 2005 Jan-Feb;57(1):14-22. Pharmacol Rep. 2005. PMID: 15849373 Free article. Review.
Moreover, experiments performed on animals and in vitro data also suggest that L-arginine may have a complex antiaggregatory, anticoagulatory and profibrinolytic effect. Therefore, a novel therapeutic potential of L-arginine should be taken into consid …
Moreover, experiments performed on animals and in vitro data also suggest that L-arginine may have a complex antiaggregatory, …
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Schwedhelm E, Maas R, Freese R, Jung D, Lukacs Z, Jambrecina A, Spickler W, Schulze F, Böger RH. Schwedhelm E, et al. Br J Clin Pharmacol. 2008 Jan;65(1):51-9. doi: 10.1111/j.1365-2125.2007.02990.x. Epub 2007 Jul 27. Br J Clin Pharmacol. 2008. PMID: 17662090 Free PMC article. Clinical Trial.
In contrast, L-citrulline is readily absorbed and at least in part converted to L-arginine. ...RESULTS: L-Citrulline dose-dependently increased AUC and C(max) of plasma L-arginine concentration more effectively than L-arginine
In contrast, L-citrulline is readily absorbed and at least in part converted to L-arginine. ...RESULTS: L-Citrul …
Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review.
Rashid J, Kumar SS, Job KM, Liu X, Fike CD, Sherwin CMT. Rashid J, et al. Paediatr Drugs. 2020 Jun;22(3):279-293. doi: 10.1007/s40272-020-00384-5. Paediatr Drugs. 2020. PMID: 32140997 Review.
In clinical studies in adults, L-arginine, an endogenous amino acid, was reported to improve cardiovascular function in hypertension, pulmonary hypertension, preeclampsia, angina, and MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) …
In clinical studies in adults, L-arginine, an endogenous amino acid, was reported to improve cardiovascular function in hypert …
[Influence of L-arginine on development of atherosclerosis: what is the therapeutically assured?].
Bode-Böger SM. Bode-Böger SM. Dtsch Med Wochenschr. 2005 Mar 18;130(11):593-8. doi: 10.1055/s-2005-865070. Dtsch Med Wochenschr. 2005. PMID: 15761791 Review. German.
The pharmacokinetics of L-arginine have been investigated, side effects are rare and mostly mild and dose-dependent. Several possible mechanisms of action of L-arginine are discussed. An assessment of L-arginine as a therapeutic agent fro …
The pharmacokinetics of L-arginine have been investigated, side effects are rare and mostly mild and dose-dependent. Several p …
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