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1994 1
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1999 1
2000 1
2001 1
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2003 2
2004 4
2005 2
2006 8
2007 3
2008 15
2009 8
2010 6
2011 3
2012 2
2016 1
2017 4
2020 1
2021 1
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2016 IMS Recommendations on women's midlife health and menopause hormone therapy.
Baber RJ, Panay N, Fenton A; IMS Writing Group. Baber RJ, et al. Climacteric. 2016 Apr;19(2):109-50. doi: 10.3109/13697137.2015.1129166. Epub 2016 Feb 12. Climacteric. 2016. PMID: 26872610
The International Menopause Society (IMS) has produced these new 2016 recommendations on women's midlife health and menopause hormone therapy (MHT) to help guide health-care professionals in optimizing their management of women in the menopause transition and …
The International Menopause Society (IMS) has produced these new 2016 recommendations on women's midlife health and menopause
The evidence base for HRT: what can we believe?
Langer RD. Langer RD. Climacteric. 2017 Apr;20(2):91-96. doi: 10.1080/13697137.2017.1280251. Epub 2017 Mar 10. Climacteric. 2017. PMID: 28281363 Review.
Prior to the unexpected early termination of the Women's Health Initiative (WHI) trial of continuous conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA), the prevailing view was that hormone replacement therapy (HRT) was a low-risk intervention with immediate …
Prior to the unexpected early termination of the Women's Health Initiative (WHI) trial of continuous conjugated equine estrogens (CEE) and m …
Calcium plus vitamin D supplementation and the risk of fractures.
Jackson RD, LaCroix AZ, Gass M, Wallace RB, Robbins J, Lewis CE, Bassford T, Beresford SA, Black HR, Blanchette P, Bonds DE, Brunner RL, Brzyski RG, Caan B, Cauley JA, Chlebowski RT, Cummings SR, Granek I, Hays J, Heiss G, Hendrix SL, Howard BV, Hsia J, Hubbell FA, Johnson KC, Judd H, Kotchen JM, Kuller LH, Langer RD, Lasser NL, Limacher MC, Ludlam S, Manson JE, Margolis KL, McGowan J, Ockene JK, O'Sullivan MJ, Phillips L, Prentice RL, Sarto GE, Stefanick ML, Van Horn L, Wactawski-Wende J, Whitlock E, Anderson GL, Assaf AR, Barad D; Women's Health Initiative Investigators. Jackson RD, et al. Among authors: langer rd. N Engl J Med. 2006 Feb 16;354(7):669-83. doi: 10.1056/NEJMoa055218. N Engl J Med. 2006. PMID: 16481635 Free article. Clinical Trial.
Calcium plus vitamin D supplementation and the risk of colorectal cancer.
Wactawski-Wende J, Kotchen JM, Anderson GL, Assaf AR, Brunner RL, O'Sullivan MJ, Margolis KL, Ockene JK, Phillips L, Pottern L, Prentice RL, Robbins J, Rohan TE, Sarto GE, Sharma S, Stefanick ML, Van Horn L, Wallace RB, Whitlock E, Bassford T, Beresford SA, Black HR, Bonds DE, Brzyski RG, Caan B, Chlebowski RT, Cochrane B, Garland C, Gass M, Hays J, Heiss G, Hendrix SL, Howard BV, Hsia J, Hubbell FA, Jackson RD, Johnson KC, Judd H, Kooperberg CL, Kuller LH, LaCroix AZ, Lane DS, Langer RD, Lasser NL, Lewis CE, Limacher MC, Manson JE; Women's Health Initiative Investigators. Wactawski-Wende J, et al. Among authors: langer rd. N Engl J Med. 2006 Feb 16;354(7):684-96. doi: 10.1056/NEJMoa055222. N Engl J Med. 2006. PMID: 16481636 Free article. Clinical Trial.
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial.
Howard BV, Van Horn L, Hsia J, Manson JE, Stefanick ML, Wassertheil-Smoller S, Kuller LH, LaCroix AZ, Langer RD, Lasser NL, Lewis CE, Limacher MC, Margolis KL, Mysiw WJ, Ockene JK, Parker LM, Perri MG, Phillips L, Prentice RL, Robbins J, Rossouw JE, Sarto GE, Schatz IJ, Snetselaar LG, Stevens VJ, Tinker LF, Trevisan M, Vitolins MZ, Anderson GL, Assaf AR, Bassford T, Beresford SA, Black HR, Brunner RL, Brzyski RG, Caan B, Chlebowski RT, Gass M, Granek I, Greenland P, Hays J, Heber D, Heiss G, Hendrix SL, Hubbell FA, Johnson KC, Kotchen JM. Howard BV, et al. Among authors: langer rd. JAMA. 2006 Feb 8;295(6):655-66. doi: 10.1001/jama.295.6.655. JAMA. 2006. PMID: 16467234 Clinical Trial.
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial.
Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, Bonds D, Brunner R, Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, Hays J, Heiss G, Hendrix S, Howard BV, Hsia J, Hubbell A, Jackson R, Johnson KC, Judd H, Kotchen JM, Kuller L, LaCroix AZ, Lane D, Langer RD, Lasser N, Lewis CE, Manson J, Margolis K, Ockene J, O'Sullivan MJ, Phillips L, Prentice RL, Ritenbaugh C, Robbins J, Rossouw JE, Sarto G, Stefanick ML, Van Horn L, Wactawski-Wende J, Wallace R, Wassertheil-Smoller S; Women's Health Initiative Steering Committee. Anderson GL, et al. Among authors: langer rd. JAMA. 2004 Apr 14;291(14):1701-12. doi: 10.1001/jama.291.14.1701. JAMA. 2004. PMID: 15082697 Free article. Clinical Trial.
Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association.
El Khoudary SR, Aggarwal B, Beckie TM, Hodis HN, Johnson AE, Langer RD, Limacher MC, Manson JE, Stefanick ML, Allison MA; American Heart Association Prevention Science Committee of the Council on Epidemiology and Prevention; and Council on Cardiovascular and Stroke Nursing. El Khoudary SR, et al. Among authors: langer rd. Circulation. 2020 Dec 22;142(25):e506-e532. doi: 10.1161/CIR.0000000000000912. Epub 2020 Nov 30. Circulation. 2020. PMID: 33251828
This observation led to the hypothesis that the menopause transition (MT) contributes to the increase in coronary heart disease risk. Over the past 20 years, longitudinal studies of women traversing menopause have contributed significantly to our understanding of th …
This observation led to the hypothesis that the menopause transition (MT) contributes to the increase in coronary heart disease risk. …
Postmenopausal hormone therapy: critical reappraisal and a unified hypothesis.
Phillips LS, Langer RD. Phillips LS, et al. Among authors: langer rd. Fertil Steril. 2005 Mar;83(3):558-66. doi: 10.1016/j.fertnstert.2004.11.012. Fertil Steril. 2005. PMID: 15749481 Review.
CONCLUSION(S): The unified hypothesis predicts that hormone therapy initiated at the time of menopause should produce a decrease in CHD over time. In contrast, hormone therapy begun years after menopause should produce an increase in CHD events shortly after therapy …
CONCLUSION(S): The unified hypothesis predicts that hormone therapy initiated at the time of menopause should produce a decrease in C …
Postmenopausal hormone therapy and migraine headache.
Misakian AL, Langer RD, Bensenor IM, Cook NR, Manson JE, Buring JE, Rexrode KM. Misakian AL, et al. Among authors: langer rd. J Womens Health (Larchmt). 2003 Dec;12(10):1027-36. doi: 10.1089/154099903322643956. J Womens Health (Larchmt). 2003. PMID: 14709191
Women with migraine headache were significantly younger, had a younger age at menopause, were more likely to have had a surgical menopause, and were more likely to be current users of HT. After adjusting for age, race, smoking, alcohol use, ever use of oral contrace …
Women with migraine headache were significantly younger, had a younger age at menopause, were more likely to have had a surgical m
Have we come full circle - or moved forward? The Women's Health Initiative 10 years on.
Langer RD, Manson JE, Allison MA. Langer RD, et al. Climacteric. 2012 Jun;15(3):206-12. doi: 10.3109/13697137.2012.666916. Climacteric. 2012. PMID: 22612605 Review.
These trials were primarily designed to test whether women considerably past menopause, and mostly asymptomatic, experienced treatment benefits from HRT expected from studies of generally symptomatic women who started near menopause. ...We have come full circle in s …
These trials were primarily designed to test whether women considerably past menopause, and mostly asymptomatic, experienced treatmen …
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