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Common Genetic Variants in the Complement System and their Potential Link with Disease Susceptibility and Outcome of Invasive Bacterial Infection.

van den Broek B, van der Flier M, de Groot R, de Jonge MI, Langereis JD. van den Broek B, et al. Among authors: langereis jd. J Innate Immun. 2020;12(2):131-141. doi: 10.1159/000500545. Epub 2019 Jul 3. J Innate Immun. 2020. PMID: 31269507 Free PMC article. Review.

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Quantitative multiplex profiling of the complement system to diagnose complement-mediated diseases.

Willems E, Lorés-Motta L, Zanichelli A, Suffritti C, van der Flier M, van der Molen RG, Langereis JD, van Drongelen J, van den Heuvel LP, Volokhina E, van de Kar NC, Keizer-Garritsen J, Levin M, Herberg JA, Martinon-Torres F, Wessels HJ, de Breuk A, Fauser S, Hoyng CB, den Hollander AI, de Groot R, van Gool AJ, Gloerich J, de Jonge MI. Willems E, et al. Among authors: langereis jd. Clin Transl Immunology. 2020 Dec 9;9(12):e1225. doi: 10.1002/cti2.1225. eCollection 2020. Clin Transl Immunology. 2020. PMID: 33318796 Free PMC article.

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Viral-bacterial (co-)occurrence in the upper airways and the risk of childhood pneumonia in resource-limited settings.

Ngocho JS, Minja L, van der Gaast-de Jongh CE, Rahamat-Langendoen JC, Langereis JD, Mmbaga BT, de Jonge MI. Ngocho JS, et al. Among authors: langereis jd. J Infect. 2020 Aug;81(2):213-220. doi: 10.1016/j.jinf.2020.06.013. Epub 2020 Jun 10. J Infect. 2020. PMID: 32533999 Free article.

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Unraveling Haemophilus influenzae virulence mechanisms enable discovery of new targets for antimicrobials and vaccines.

Langereis JD, de Jonge MI. Langereis JD, et al. Curr Opin Infect Dis. 2020 Jun;33(3):231-237. doi: 10.1097/QCO.0000000000000645. Curr Opin Infect Dis. 2020. PMID: 32304471

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Serum IgM and C-Reactive Protein Binding to Phosphorylcholine of Nontypeable Haemophilus influenzae Increases Complement-Mediated Killing.

Langereis JD, van der Pasch ES, de Jonge MI. Langereis JD, et al. Infect Immun. 2019 Jul 23;87(8):e00299-19. doi: 10.1128/IAI.00299-19. Print 2019 Aug. Infect Immun. 2019. PMID: 31109949 Free PMC article.

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Uptake of Sialic Acid by Nontypeable Haemophilus influenzae Increases Complement Resistance through Decreasing IgM-Dependent Complement Activation.

Oerlemans MMP, Moons SJ, Heming JJA, Boltje TJ, de Jonge MI, Langereis JD. Oerlemans MMP, et al. Among authors: langereis jd. Infect Immun. 2019 May 21;87(6):e00077-19. doi: 10.1128/IAI.00077-19. Print 2019 Jun. Infect Immun. 2019. PMID: 30936154 Free PMC article.

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Eculizumab impairs Neisseria meningitidis serogroup B killing in whole blood despite 4CMenB vaccination of PNH patients.

Langereis JD, van den Broek B, Franssen S, Joosten I, Blijlevens NMA, de Jonge MI, Langemeijer S. Langereis JD, et al. Blood Adv. 2020 Aug 11;4(15):3615-3620. doi: 10.1182/bloodadvances.2020002497. Blood Adv. 2020. PMID: 32766853 Free PMC article.

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Aetiology of acute febrile illness in children in a high malaria transmission area in West Africa.

Kaboré B, Post A, Lompo P, Bognini JD, Diallo S, Kam BTD, Rahamat-Langendoen J, Wertheim HFL, van Opzeeland F, Langereis JD, de Jonge MI, Tinto H, Jacobs J, van der Ven AJ, de Mast Q. Kaboré B, et al. Among authors: langereis jd. Clin Microbiol Infect. 2020 Jun 4:S1198-743X(20)30306-2. doi: 10.1016/j.cmi.2020.05.029. Online ahead of print. Clin Microbiol Infect. 2020. PMID: 32505586 Free article.

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Antibody Binding and Complement-Mediated Killing of Invasive Haemophilus influenzae Isolates from Spain, Portugal, and the Netherlands.

Dudukina E, de Smit L, Verhagen GJA, van de Ende A, Marimón JM, Bajanca-Lavado P, Ardanuy C, Marti S, de Jonge MI, Langereis JD. Dudukina E, et al. Among authors: langereis jd. Infect Immun. 2020 Sep 18;88(10):e00454-20. doi: 10.1128/IAI.00454-20. Print 2020 Sep 18. Infect Immun. 2020. PMID: 32719154

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Multi-component meningococcal serogroup B (MenB)-4C vaccine induces effective opsonophagocytic killing in children with a complement deficiency.

van den Broek B, van Els CACM, Kuipers B, van Aerde K, Henriet SS, de Groot R, de Jonge MI, Langereis JD, van der Flier M. van den Broek B, et al. Among authors: langereis jd. Clin Exp Immunol. 2019 Dec;198(3):381-389. doi: 10.1111/cei.13368. Epub 2019 Oct 1. Clin Exp Immunol. 2019. PMID: 31487400 Free PMC article.

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