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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 2
1971 4
1972 1
1973 4
1974 1
1976 10
1977 4
1978 3
1979 4
1980 12
1981 9
1982 19
1983 10
1984 13
1985 11
1986 12
1987 19
1988 23
1989 21
1990 23
1991 7
1992 19
1993 12
1994 19
1995 11
1996 13
1997 11
1998 9
1999 12
2000 10
2001 5
2002 11
2003 14
2004 13
2005 11
2006 11
2007 6
2008 12
2009 19
2010 21
2011 17
2012 17
2013 17
2014 16
2015 15
2016 17
2017 21
2018 31
2019 26
2020 36
2021 42
2022 15
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677 results
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Mushroom polysaccharide lentinan for treating different types of cancers: A review of 12 years clinical studies in China.
Zhang M, Zhang Y, Zhang L, Tian Q. Zhang M, et al. Prog Mol Biol Transl Sci. 2019;163:297-328. doi: 10.1016/bs.pmbts.2019.02.013. Epub 2019 Apr 4. Prog Mol Biol Transl Sci. 2019. PMID: 31030752 Review.
It is the second largest cultivated and the most popular edible mushroom in the world known as "Xianggu" in China and "Shiitake" in Japan. Lentinan is a polysaccharide extracted from Lentinula edodes. beta-Glucan is the major bioactive component in lentinan with imm …
It is the second largest cultivated and the most popular edible mushroom in the world known as "Xianggu" in China and "Shiitake" in Japan. …
Lentinan as a natural stabilizer with bioactivities for preparation of drug-drug nanosuspensions.
Suo Z, Sun Q, Peng X, Zhang S, Gan N, Zhao L, Yuan N, Zhang Y, Li H. Suo Z, et al. Int J Biol Macromol. 2021 Aug 1;184:101-108. doi: 10.1016/j.ijbiomac.2021.06.056. Epub 2021 Jun 10. Int J Biol Macromol. 2021. PMID: 34119545
Transmission electron microscopy findings indicated that lentinan stabilized the nanosuspensions by steric manner. Hydrogen bonds and hydrophobic interactions were found between regorafenib and lentinan by molecular dynamics simulation. ...Lentinan as a natur …
Transmission electron microscopy findings indicated that lentinan stabilized the nanosuspensions by steric manner. Hydrogen bonds and …
Protective Effects of Lentinan Against Lipopolysaccharide-Induced Mastitis in Mice.
Yin H, Xue G, Dai A, Wu H. Yin H, et al. Front Pharmacol. 2021 Sep 24;12:755768. doi: 10.3389/fphar.2021.755768. eCollection 2021. Front Pharmacol. 2021. PMID: 34630124 Free PMC article.
These results suggested that LPS-induced activation of the Wnt/beta-catenin pathway was suppressed by lentinan administration. In vitro, we observed that the mouse mammary epithelial cell (mMEC) viability was not affected by lentinan treatment. ...Thus, the results …
These results suggested that LPS-induced activation of the Wnt/beta-catenin pathway was suppressed by lentinan administration. In vit …
Lentinan as an immunotherapeutic for treating lung cancer: a review of 12 years clinical studies in China.
Zhang Y, Zhang M, Jiang Y, Li X, He Y, Zeng P, Guo Z, Chang Y, Luo H, Liu Y, Hao C, Wang H, Zhang G, Zhang L. Zhang Y, et al. J Cancer Res Clin Oncol. 2018 Nov;144(11):2177-2186. doi: 10.1007/s00432-018-2718-1. Epub 2018 Jul 24. J Cancer Res Clin Oncol. 2018. PMID: 30043277 Review.
PURPOSE: Lentinan is a polysaccharide extracted from Shiitake mushrooms that have been used to improve general health for thousands of years in Asia. Lentinan injection is a clinically approved drug in several countries in Asia. ...
PURPOSE: Lentinan is a polysaccharide extracted from Shiitake mushrooms that have been used to improve general health for thousands o …
Intrathoracic infusion therapy with Lentinan and chemical irritants for malignant pleural effusion: a systematic review and meta-analysis of 65 randomized controlled trials.
Xiao Z, Jiang Y, Chen XF, Wang CQ, Zheng XT, Xu WH, Zou XX, Zhou JM, Yang YH, Hu SS, Shan LJ, Cai QY, Tang YH, Feng JH, Xiao X. Xiao Z, et al. Phytomedicine. 2020 Jun 1;76:153260. doi: 10.1016/j.phymed.2020.153260. Online ahead of print. Phytomedicine. 2020. PMID: 32535483 Review.
BACKGROUND: Aderivative of Shiitake mushrooms, Lentinan is used to control malignant pleural effusion (MPE) through intrathoracic infusion. ...METHODS: We collected all randomized controlled trials (RCTs) regarding Lentinan plus chemical irritants from Chinese and E …
BACKGROUND: Aderivative of Shiitake mushrooms, Lentinan is used to control malignant pleural effusion (MPE) through intrathoracic inf …
Lentinan combined with cisplatin for the treatment of non-small cell lung cancer.
Zhao C, Yan H, Pang W, Wu T, Kong X, Li X, Liu H, Zhao L, Liang F, Jia Y. Zhao C, et al. Medicine (Baltimore). 2021 Mar 26;100(12):e25220. doi: 10.1097/MD.0000000000025220. Medicine (Baltimore). 2021. PMID: 33761711 Free article.
OBJECTIVE: This study aimed to evaluate the effectiveness and safety of lentinan combined with cisplatin thoracic injection in the treatment of lung cancer. ...CONCLUSIONS: The current evidence prompted that Lentinan combined with cisplatin in thoracic injection mig …
OBJECTIVE: This study aimed to evaluate the effectiveness and safety of lentinan combined with cisplatin thoracic injection in the tr …
Lentinan Dermatitis: Time to Rename Shiitake Dermatitis.
Cruzval-O'Reilly E, Morrell DS, Lugo-Somolinos A. Cruzval-O'Reilly E, et al. Dermatitis. 2021 Jan-Feb 01;32(1):e16-e18. doi: 10.1097/DER.0000000000000647. Dermatitis. 2021. PMID: 33449484 No abstract available.
Lentinan reduces tumor progression by enhancing gemcitabine chemotherapy in urothelial bladder cancer.
Sun M, Zhao W, Xie Q, Zhan Y, Wu B. Sun M, et al. Surg Oncol. 2015 Mar;24(1):28-34. doi: 10.1016/j.suronc.2014.11.002. Epub 2014 Nov 20. Surg Oncol. 2015. PMID: 25434982 Review.
Survival-related protein expression was analyzed by western blotting. Increased concentrations of lentinan, or lentinan combined with gemcitabine, positively correlated with decreased T24 cell proliferation. Lentinan combined with gemcitabine chemotherapy sig …
Survival-related protein expression was analyzed by western blotting. Increased concentrations of lentinan, or lentinan combin …
Molecular dynamics simulation of lentinan and its interaction with the innate receptor dectin-1.
Wu X, Zheng Z, Guo T, Wang K, Zhang Y. Wu X, et al. Int J Biol Macromol. 2021 Feb 28;171:527-538. doi: 10.1016/j.ijbiomac.2021.01.032. Epub 2021 Jan 8. Int J Biol Macromol. 2021. PMID: 33428957
Lentinan, a beta-1,3-D-glucan, is clinically used as an immune enhancement drug for tumor therapy. ...We proved by computational simulation that lentinan can maintain its triple-helix through hydrogen network and disclosed some structural properties of lentinan …
Lentinan, a beta-1,3-D-glucan, is clinically used as an immune enhancement drug for tumor therapy. ...We proved by computational simu …
Lentinan Attenuates Damage of the Small Intestinal Mucosa, Liver, and Lung in Mice with Gut-Origin Sepsis.
Kuang Z, Jin T, Wu C, Zong Y, Yin P, Dong W, Lin X, You W, Zhang C, Wang L, Liu Y, Ren S, Yin J, Xu H. Kuang Z, et al. J Immunol Res. 2021 Nov 8;2021:2052757. doi: 10.1155/2021/2052757. eCollection 2021. J Immunol Res. 2021. PMID: 34790828 Free PMC article.
This study is aimed at exploring the effects of lentinan on small intestinal mucosa as well as lung and liver injury in mice with gut-origin sepsis. ...The mice were randomly divided into six groups: sham operation group (sham), gut-origin sepsis model group (CLP), ulinast …
This study is aimed at exploring the effects of lentinan on small intestinal mucosa as well as lung and liver injury in mice with gut …
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