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1,568 results

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Page 1
Meiosis.
Hillers KJ, Jantsch V, Martinez-Perez E, Yanowitz JL. Hillers KJ, et al. WormBook. 2017 May 4;2017:1-43. doi: 10.1895/wormbook.1.178.1. WormBook. 2017. PMID: 26694509 Free PMC article. Review.
The molecular regulatory mechanisms of meiotic arrest and resumption in Oocyte development and maturation.
Pei Z, Deng K, Xu C, Zhang S. Pei Z, et al. Reprod Biol Endocrinol. 2023 Oct 2;21(1):90. doi: 10.1186/s12958-023-01143-0. Reprod Biol Endocrinol. 2023. PMID: 37784186 Free PMC article. Review.
In human female primordial germ cells, the transition from mitosis to meiosis begins from the fetal stage. In germ cells, meiosis is arrested at the diplotene stage of prophase in meiosis I (MI) after synapsis and recombination of homologous chromosomes, which canno …
In human female primordial germ cells, the transition from mitosis to meiosis begins from the fetal stage. In germ cells, meiosis is …
ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression.
Xu J, Gao J, Liu J, Huang X, Zhang H, Ma A, Ye J, Zhang X, Li Y, Yang G, Yin H, Khan R, Li T, Fan S, Jiang X, Zhang Y, Jiang H, Ma H, Shi Q. Xu J, et al. Cell Rep. 2022 Mar 22;38(12):110540. doi: 10.1016/j.celrep.2022.110540. Cell Rep. 2022. PMID: 35320728 Free article.
The DSB machinery, which induces the programmed DNA double-strand breaks (DSBs) in the leptotene and zygotene stages during meiosis, is suppressed before the onset of the pachytene stage. ...The deletion of Zfp541 in mice causes the aberrant recruitment of DSB machi …
The DSB machinery, which induces the programmed DNA double-strand breaks (DSBs) in the leptotene and zygotene stages during meiosis, …
Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions.
Yoshimura S, Shimada R, Kikuchi K, Kawagoe S, Abe H, Iisaka S, Fujimura S, Yasunaga KI, Usuki S, Tani N, Ohba T, Kondoh E, Saio T, Araki K, Ishiguro KI. Yoshimura S, et al. Nat Commun. 2024 Apr 29;15(1):3330. doi: 10.1038/s41467-024-47601-0. Nat Commun. 2024. PMID: 38684656 Free PMC article.
Genetic analyzes and single-cell RNA-sequencing demonstrate that HSF5 is essential for progression beyond the pachytene stage under non-stress conditions rather than heat stress. Chromatin binding analysis in vivo and DNA-binding assays in vitro suggest that HSF5 binds to …
Genetic analyzes and single-cell RNA-sequencing demonstrate that HSF5 is essential for progression beyond the pachytene stage under n …
Nuclear reprogramming.
Halley-Stott RP, Pasque V, Gurdon JB. Halley-Stott RP, et al. Development. 2013 Jun;140(12):2468-71. doi: 10.1242/dev.092049. Development. 2013. PMID: 23715540 Free article. Review.
HSF5 Deficiency Causes Male Infertility Involving Spermatogenic Arrest at Meiotic Prophase I in Humans and Mice.
Liu M, Wang L, Li Y, Zhi E, Shen G, Jiang X, Li D, Zhao X, Ruan T, Jiang C, Wang X, Zhang X, Zheng Y, Wu B, Ou N, Zhao G, Dai S, Zhou R, Yang L, Yang Y, Liu H, Shen Y. Liu M, et al. Adv Sci (Weinh). 2024 Sep;11(33):e2402412. doi: 10.1002/advs.202402412. Epub 2024 Jul 3. Adv Sci (Weinh). 2024. PMID: 38958533 Free PMC article.
Testicular histologic findings in the patients reveal rare postmeiotic germ cells resulting from meiotic prophase I arrest. Hsf5 knockout (KO) mice confirms that the loss of HSF5 causes defects in meiotic recombination, crossover formation, sex chromosome syn …
Testicular histologic findings in the patients reveal rare postmeiotic germ cells resulting from meiotic prophase I arr …
Holliday junction-ZMM protein feedback enables meiotic crossover assurance.
Henggeler A, Orlić L, Velikov D, Matos J. Henggeler A, et al. Nature. 2025 Nov;647(8090):766-775. doi: 10.1038/s41586-025-09559-x. Epub 2025 Sep 24. Nature. 2025. PMID: 40993383 Free PMC article.
Despite posing a risk to chromosome segregation, HJs accumulate during meiotic prophase I as intermediates in the process of crossing-over(2,3). Whether HJs have additional regulatory functions remains unclear. ...
Despite posing a risk to chromosome segregation, HJs accumulate during meiotic prophase I as intermediates in the proce …
1,568 results