Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2011 1
2012 1
2013 2
2014 1
2015 1
2016 1
2017 1
2018 1
2019 1
2020 4
2021 0
Text availability
Article attribute
Article type
Publication date

Search Results

13 results
Results by year
Filters applied: . Clear all
Page 1
Understanding microcephaly through the study of centrosome regulation in Drosophila neural stem cells.
Robinson BV, Faundez V, Lerit DA. Robinson BV, et al. Among authors: lerit da. Biochem Soc Trans. 2020 Oct 30;48(5):2101-2115. doi: 10.1042/BST20200261. Biochem Soc Trans. 2020. PMID: 32897294 Free PMC article. Review.
Among the known heritable microcephaly genes, a significant proportion are annotated with centrosome-related ontologies. Centrosomes are microtubule-organizing centers, and they play fundamental roles in the proliferation of the neuronal progenitors, the neural stem …
Among the known heritable microcephaly genes, a significant proportion are annotated with centrosome-related ontologies. Centrosom
Drosophila pericentrin-like protein promotes the formation of primordial germ cells.
Fang J, Lerit DA. Fang J, et al. Among authors: lerit da. Genesis. 2020 Mar;58(3-4):e23347. doi: 10.1002/dvg.23347. Epub 2019 Nov 27. Genesis. 2020. PMID: 31774613 Free PMC article.
We previously identified a requirement for the centrosome protein Centrosomin (Cnn) in PGC formation. Cnn interacts directly with Pericentrin-like protein (PLP) to form a centrosome scaffold structure required for pericentriolar material recruitment and organization …
We previously identified a requirement for the centrosome protein Centrosomin (Cnn) in PGC formation. Cnn interacts directly with Per …
Centrosomes are multifunctional regulators of genome stability.
Lerit DA, Poulton JS. Lerit DA, et al. Chromosome Res. 2016 Jan;24(1):5-17. doi: 10.1007/s10577-015-9506-4. Chromosome Res. 2016. PMID: 26658800 Free PMC article. Review.
As a result, the centrosome is itself a highly regulated entity. Here, we review evidence concerning the significance of the centrosome in promoting genome integrity. Recent advances permitting acute and persistent centrosome removal suggest we still have muc …
As a result, the centrosome is itself a highly regulated entity. Here, we review evidence concerning the significance of the centr
centrocortin RNA localization to centrosomes is regulated by FMRP and facilitates error-free mitosis.
Ryder PV, Fang J, Lerit DA. Ryder PV, et al. Among authors: lerit da. J Cell Biol. 2020 Dec 7;219(12):e202004101. doi: 10.1083/jcb.202004101. J Cell Biol. 2020. PMID: 33196763 Free PMC article.
Centrosomes are microtubule-organizing centers required for error-free mitosis and embryonic development. ...We identify a novel role for the fragile-X mental retardation protein in the posttranscriptional regulation of a model centrosomal mRNA, centrocortin (cen).
Centrosomes are microtubule-organizing centers required for error-free mitosis and embryonic development. ...We identify a novel role
Quantitative analysis of subcellular distributions with an open-source, object-based tool.
Ryder PV, Lerit DA. Ryder PV, et al. Among authors: lerit da. Biol Open. 2020 Oct 19;9(10):bio055228. doi: 10.1242/bio.055228. Biol Open. 2020. PMID: 32973081 Free PMC article.
To test the utility of the SubcellularDistribution pipeline, we examined the subcellular distribution of mRNA relative to centrosomes within syncytial Drosophila embryos. Centrosomes are microtubule-organizing centers, and RNA enrichments at centrosomes are o …
To test the utility of the SubcellularDistribution pipeline, we examined the subcellular distribution of mRNA relative to centrosomes
Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function.
Lerit DA, Jordan HA, Poulton JS, Fagerstrom CJ, Galletta BJ, Peifer M, Rusan NM. Lerit DA, et al. J Cell Biol. 2015 Jul 6;210(1):79-97. doi: 10.1083/jcb.201503117. J Cell Biol. 2015. PMID: 26150390 Free PMC article.
Pericentriolar material (PCM) mediates the microtubule (MT) nucleation and anchoring activity of centrosomes. A scaffold organized by Centrosomin (Cnn) serves to ensure proper PCM architecture and functional changes in centrosome activity with each cell cycle. ...Ou …
Pericentriolar material (PCM) mediates the microtubule (MT) nucleation and anchoring activity of centrosomes. A scaffold organized by …
Organelle asymmetry for proper fitness, function, and fate.
Lerit DA, Smyth JT, Rusan NM. Lerit DA, et al. Chromosome Res. 2013 May;21(3):271-86. doi: 10.1007/s10577-013-9350-3. Chromosome Res. 2013. PMID: 23681659 Free PMC article. Review.
During cellular division, centrosomes are tasked with building the bipolar mitotic spindle, which partitions the cellular contents into two daughter cells. ...In this review, we highlight the conservation of nonrandom centrosome segregation in asymmetrically dividin …
During cellular division, centrosomes are tasked with building the bipolar mitotic spindle, which partitions the cellular contents in …
Germ Cell-less Promotes Centrosome Segregation to Induce Germ Cell Formation.
Lerit DA, Shebelut CW, Lawlor KJ, Rusan NM, Gavis ER, Schedl P, Deshpande G. Lerit DA, et al. Cell Rep. 2017 Jan 24;18(4):831-839. doi: 10.1016/j.celrep.2016.12.074. Cell Rep. 2017. PMID: 28122234 Free PMC article.
To date, mechanisms that modulate centrosome behavior to engineer PGC development have remained elusive. ...We conclude Gcl functions as a key regulator of centrosome separation required for proper PGC development....
To date, mechanisms that modulate centrosome behavior to engineer PGC development have remained elusive. ...We conclude Gcl functions …
PLP inhibits the activity of interphase centrosomes to ensure their proper segregation in stem cells.
Lerit DA, Rusan NM. Lerit DA, et al. J Cell Biol. 2013 Sep 30;202(7):1013-22. doi: 10.1083/jcb.201303141. J Cell Biol. 2013. PMID: 24081489 Free PMC article.
Centrosomes determine the mitotic axis of asymmetrically dividing stem cells. ...We show that PLP is enriched on the inactive interphase centrosome, where it blocks recruitment of the master regulator of centrosome maturation, Polo kinase. ...
Centrosomes determine the mitotic axis of asymmetrically dividing stem cells. ...We show that PLP is enriched on the inactive interph
13 results
You have reached the last page of results. A maximum of 10,000 results are available.
Jump to page