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Year Number of Results
2009 1
2011 1
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Page 1
International society of sports nutrition position stand: β-hydroxy-β-methylbutyrate (HMB).
Rathmacher JA, Pitchford LM, Stout JR, Townsend JR, Jäger R, Kreider RB, Campbell BI, Kerksick CM, Harty PS, Candow DG, Roberts BM, Arent SM, Kalman DS, Antonio J. Rathmacher JA, et al. J Int Soc Sports Nutr. 2025 Dec;22(1):2434734. doi: 10.1080/15502783.2024.2434734. Epub 2024 Dec 19. J Int Soc Sports Nutr. 2025. PMID: 39699070 Free PMC article. Review.
There may be improvements in glucose metabolism in younger adults. 4. The primary mode of action of HMB appears to be through its dual mechanism to enhance muscle protein synthesis and suppress muscle protein breakdown. ...HMB may be effe …
There may be improvements in glucose metabolism in younger adults. 4. The primary mode of action of HMB appears to be through its dua …
Leucine as a treatment for muscle wasting: a critical review.
Ham DJ, Caldow MK, Lynch GS, Koopman R. Ham DJ, et al. Clin Nutr. 2014 Dec;33(6):937-45. doi: 10.1016/j.clnu.2014.09.016. Clin Nutr. 2014. PMID: 25444557 Review.
During amino acid abundance increased activity of mTORC1 drives protein synthesis and growth. In skeletal muscle, it has been clearly demonstrated that of all the amino acids, leucine is the most potent stimulator of mTORC1 and protein …
During amino acid abundance increased activity of mTORC1 drives protein synthesis and growth. In skeletal muscle …
Leucine and Mammalian Target of Rapamycin-Dependent Activation of Muscle Protein Synthesis in Aging.
De Bandt JP. De Bandt JP. J Nutr. 2016 Dec;146(12):2616S-2624S. doi: 10.3945/jn.116.234518. Epub 2016 Nov 9. J Nutr. 2016. PMID: 27934653 Free article. Review.
Indeed, it acts independently of growth factors and leads to enhanced cap-dependent mRNA translation initiation and increased protein synthesis. Leucine acts as a signaling molecule directly at the muscle level via the activation of mammalian/mechan …
Indeed, it acts independently of growth factors and leads to enhanced cap-dependent mRNA translation initiation and increased protein …
Regulation of protein synthesis by amino acids in muscle of neonates.
Suryawan A, Davis TA. Suryawan A, et al. Front Biosci (Landmark Ed). 2011 Jan 1;16(4):1445-60. doi: 10.2741/3798. Front Biosci (Landmark Ed). 2011. PMID: 21196241 Free PMC article. Review.
The amino acid signaling pathway leading to the stimulation of protein synthesis has not been fully elucidated. Among the amino acids, leucine is considered to be a principal anabolic agent that regulates protein synthesis. mTORC1, which …
The amino acid signaling pathway leading to the stimulation of protein synthesis has not been fully elucidated. Among the amin …
Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling.
Drummond MJ, Dreyer HC, Fry CS, Glynn EL, Rasmussen BB. Drummond MJ, et al. J Appl Physiol (1985). 2009 Apr;106(4):1374-84. doi: 10.1152/japplphysiol.91397.2008. Epub 2009 Jan 15. J Appl Physiol (1985). 2009. PMID: 19150856 Free PMC article. Review.
In this review we discuss current findings in the human skeletal muscle literature describing the acute influence of nutrients (leucine-enriched essential amino acids in particular) and resistance exercise on muscle protein synthesis and …
In this review we discuss current findings in the human skeletal muscle literature describing the acute influence of nutrients …
Postexercise Dietary Protein Strategies to Maximize Skeletal Muscle Repair and Remodeling in Masters Endurance Athletes: A Review.
Doering TM, Reaburn PR, Phillips SM, Jenkins DG. Doering TM, et al. Int J Sport Nutr Exerc Metab. 2016 Apr;26(2):168-78. doi: 10.1123/ijsnem.2015-0102. Epub 2015 Sep 24. Int J Sport Nutr Exerc Metab. 2016. PMID: 26402439 Review.
The importance of postexercise protein feeding for endurance athletes is increasingly being acknowledged, and its role in creating a positive net muscle protein balance postexercise is well known. The potential benefits of postexercise protein feeding …
The importance of postexercise protein feeding for endurance athletes is increasingly being acknowledged, and its role in creating a …
Regulation of lysosomes in skeletal muscle during exercise, disuse and aging.
Moradi N, Sanfrancesco VC, Champsi S, Hood DA. Moradi N, et al. Free Radic Biol Med. 2024 Nov 20;225:323-332. doi: 10.1016/j.freeradbiomed.2024.09.028. Epub 2024 Sep 25. Free Radic Biol Med. 2024. PMID: 39332541 Free article. Review.
Lysosomes play a critical role as a terminal organelle in autophagy flux and in regulating protein degradation, but their function and adaptability in skeletal muscle is understudied. Lysosome functions include both housekeeping and signaling functions essential for …
Lysosomes play a critical role as a terminal organelle in autophagy flux and in regulating protein degradation, but their function an …
Review: Nutritional regulation of muscle growth in neonatal swine.
Posey EA, Davis TA. Posey EA, et al. Animal. 2023 Jul;17 Suppl 3(Suppl 3):100831. doi: 10.1016/j.animal.2023.100831. Epub 2023 Apr 28. Animal. 2023. PMID: 37263816 Free PMC article. Review.
It will focus on the regulation of protein synthesis, and especially the upstream and downstream effectors surrounding the master protein kinase, mechanistic target of rapamycin complex 1 (mTORC1) that controls …
It will focus on the regulation of protein synthesis, and especially the upstream and downstream effectors surrounding the mas …
Leucine and mTORC1: a complex relationship.
Dodd KM, Tee AR. Dodd KM, et al. Am J Physiol Endocrinol Metab. 2012 Jun 1;302(11):E1329-42. doi: 10.1152/ajpendo.00525.2011. Epub 2012 Feb 21. Am J Physiol Endocrinol Metab. 2012. PMID: 22354780 Free article. Review.
Signal transduction through mTORC1, which is centrally involved in muscle growth through enhanced protein translation, is governed by intracellular amino acid supply. The branched-chain amino acid leucine is critical for muscle growth and acts i …
Signal transduction through mTORC1, which is centrally involved in muscle growth through enhanced protein translation, …
Amino Acid Sensing in Skeletal Muscle.
Moro T, Ebert SM, Adams CM, Rasmussen BB. Moro T, et al. Trends Endocrinol Metab. 2016 Nov;27(11):796-806. doi: 10.1016/j.tem.2016.06.010. Epub 2016 Jul 19. Trends Endocrinol Metab. 2016. PMID: 27444066 Free PMC article. Review.
Here, we review evidence that mammalian/mechanistic target of rapamycin complex 1 (mTORC1)-mediated and activating transcription factor 4 (ATF4)-mediated amino acid (AA) sensing pathways, triggered by impaired AA delivery to …
Here, we review evidence that mammalian/mechanistic target of rapamycin complex 1 (mTORC …
30 results