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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
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1994 4
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1999 4
2000 15
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2002 11
2003 5
2004 7
2005 9
2006 11
2007 9
2008 14
2009 19
2010 5
2011 22
2012 20
2013 23
2014 23
2015 38
2016 48
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2018 28
2019 30
2020 29
2021 34
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595 results

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Page 1
Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial.
Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, McMurdo ME, Mets T, Seal C, Wijers SL, Ceda GP, De Vito G, Donders G, Drey M, Greig C, Holmbäck U, Narici M, McPhee J, Poggiogalle E, Power D, Scafoglieri A, Schultz R, Sieber CC, Cederholm T. Bauer JM, et al. J Am Med Dir Assoc. 2015 Sep 1;16(9):740-7. doi: 10.1016/j.jamda.2015.05.021. Epub 2015 Jul 10. J Am Med Dir Assoc. 2015. PMID: 26170041 Free article. Clinical Trial.
DESIGN: A multicenter, randomized, controlled, double-blind, 2 parallel-group trial among 380 sarcopenic primarily independent-living older adults with Short Physical Performance Battery (SPPB; 0-12) scores between 4 and 9, and a low skeletal muscle mass inde …
DESIGN: A multicenter, randomized, controlled, double-blind, 2 parallel-group trial among 380 sarcopenic primarily independent-living old …
Acute Sarcopenia: Mechanisms and Management.
Damanti S, Senini E, De Lorenzo R, Merolla A, Santoro S, Festorazzi C, Messina M, Vitali G, Sciorati C, Rovere-Querini P. Damanti S, et al. Nutrients. 2024 Oct 10;16(20):3428. doi: 10.3390/nu16203428. Nutrients. 2024. PMID: 39458423 Free PMC article. Review.
BACKGROUND: Acute sarcopenia refers to the swift decline in muscle function and mass following acute events such as illness, surgery, trauma, or burns that presents significant challenges in hospitalized older adults. ...Interventions include early mobilizati …
BACKGROUND: Acute sarcopenia refers to the swift decline in muscle function and mass following acute events such as illness, surgery, …
Nutritional interventions to improve muscle mass, muscle strength, and physical performance in older people: an umbrella review of systematic reviews and meta-analyses.
Gielen E, Beckwée D, Delaere A, De Breucker S, Vandewoude M, Bautmans I; Sarcopenia Guidelines Development Group of the Belgian Society of Gerontology and Geriatrics (BSGG). Gielen E, et al. Nutr Rev. 2021 Jan 9;79(2):121-147. doi: 10.1093/nutrit/nuaa011. Nutr Rev. 2021. PMID: 32483625 Free article.
CONCLUSIONS: Best evidence is available to recommend leucine, because it has a significant effect on muscle mass in elderly people with sarcopenia. Protein supplementation on top of resistance training is recommended to increase muscle mass and strengt …
CONCLUSIONS: Best evidence is available to recommend leucine, because it has a significant effect on muscle mass in elderly pe …
Dietary protein recommendations and the prevention of sarcopenia.
Paddon-Jones D, Rasmussen BB. Paddon-Jones D, et al. Curr Opin Clin Nutr Metab Care. 2009 Jan;12(1):86-90. doi: 10.1097/MCO.0b013e32831cef8b. Curr Opin Clin Nutr Metab Care. 2009. PMID: 19057193 Free PMC article. Review.
RECENT FINDINGS: Ageing does not inevitably reduce the anabolic response to a high-quality protein meal. Ingestion of approximately 25-30 g of protein per meal maximally stimulates muscle protein synthesis in both young and older individu …
RECENT FINDINGS: Ageing does not inevitably reduce the anabolic response to a high-quality protein meal. Ingestion of approximately 2 …
Evaluating the Leucine Trigger Hypothesis to Explain the Post-prandial Regulation of Muscle Protein Synthesis in Young and Older Adults: A Systematic Review.
Zaromskyte G, Prokopidis K, Ioannidis T, Tipton KD, Witard OC. Zaromskyte G, et al. Front Nutr. 2021 Jul 8;8:685165. doi: 10.3389/fnut.2021.685165. eCollection 2021. Front Nutr. 2021. PMID: 34307436 Free PMC article.
Background: The "leucine trigger" hypothesis was originally conceived to explain the post-prandial regulation of muscle protein synthesis (MPS). ...Aim: The primary aim of this systematic review was to qualitatively evaluate the leucine trigger …
Background: The "leucine trigger" hypothesis was originally conceived to explain the post-prandial regulation of muscle pro …
Muscle Protein Synthesis after Protein Administration in Critical Illness.
Chapple LS, Kouw IWK, Summers MJ, Weinel LM, Gluck S, Raith E, Slobodian P, Soenen S, Deane AM, van Loon LJC, Chapman MJ. Chapple LS, et al. Am J Respir Crit Care Med. 2022 Sep 15;206(6):740-749. doi: 10.1164/rccm.202112-2780OC. Am J Respir Crit Care Med. 2022. PMID: 35584344
Rationale: Dietary protein may attenuate the muscle atrophy experienced by patients in the ICU, yet protein handling is poorly understood. ...Conclusions: The capacity for critically ill patients to use ingested protein for muscle protein …
Rationale: Dietary protein may attenuate the muscle atrophy experienced by patients in the ICU, yet protein handling is …
Nutritional strategies for improving sarcopenia outcomes in older adults: A narrative review.
Goes-Santos BR, Carson BP, da Fonseca GWP, von Haehling S. Goes-Santos BR, et al. Pharmacol Res Perspect. 2024 Oct;12(5):e70019. doi: 10.1002/prp2.70019. Pharmacol Res Perspect. 2024. PMID: 39400516 Free PMC article. Review.
The development of sarcopenia is underpinned by aging, but other factors can lead to sarcopenia, such as chronic diseases, physical inactivity, inadequate dietary energy intake, and reduced protein intake (nutrition-related sarcopenia), leading to an imbalance between m …
The development of sarcopenia is underpinned by aging, but other factors can lead to sarcopenia, such as chronic diseases, physical inactivi …
Dietary protein considerations for muscle protein synthesis and muscle mass preservation in older adults.
Olaniyan ET, O'Halloran F, McCarthy AL. Olaniyan ET, et al. Nutr Res Rev. 2021 Jun;34(1):147-157. doi: 10.1017/S0954422420000219. Epub 2020 Sep 4. Nutr Res Rev. 2021. PMID: 32883378 Review.
Amino acid bioavailability is critical for muscle protein synthesis (MPS) and preservation of skeletal muscle mass (SMM). Ageing is associated with reduced responsiveness of MPS to essential amino acids (EAA). ...Reaching a conclusion on the best patte …
Amino acid bioavailability is critical for muscle protein synthesis (MPS) and preservation of skeletal muscle ma …
Consumption of whole eggs promotes greater stimulation of postexercise muscle protein synthesis than consumption of isonitrogenous amounts of egg whites in young men.
van Vliet S, Shy EL, Abou Sawan S, Beals JW, West DW, Skinner SK, Ulanov AV, Li Z, Paluska SA, Parsons CM, Moore DR, Burd NA. van Vliet S, et al. Am J Clin Nutr. 2017 Dec;106(6):1401-1412. doi: 10.3945/ajcn.117.159855. Epub 2017 Oct 4. Am J Clin Nutr. 2017. PMID: 28978542 Free article. Clinical Trial.
However, the effect of consuming protein within its natural whole-food matrix on postprandial protein metabolism remains understudied in humans.Objective: We aimed to compare the whole-body and muscle protein metabolic responses after the consum …
However, the effect of consuming protein within its natural whole-food matrix on postprandial protein metabolism remain …
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT. Scheiblich H, et al. Cell. 2021 Sep 30;184(20):5089-5106.e21. doi: 10.1016/j.cell.2021.09.007. Epub 2021 Sep 22. Cell. 2021. PMID: 34555357 Free PMC article.
Microglia are the CNS resident immune cells that react to misfolded proteins through pattern recognition receptor ligation and activation of inflammatory pathways. ...
Microglia are the CNS resident immune cells that react to misfolded proteins through pattern recognition receptor ligation and activa …
595 results