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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 6
2002 1
2003 6
2004 8
2005 10
2006 12
2007 6
2008 11
2009 6
2010 9
2011 7
2012 2
2013 11
2014 6
2015 3
2016 6
2017 5
2018 5
2019 4
2020 6
2021 1
2022 1
2023 4
2024 2
2025 4
2026 1

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129 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Efficacy and safety of montelukast-levocetirizine combination therapy in combined allergic rhinitis and asthma syndrome: a systematic review and meta-analysis.
Shao M, Sun J, Zheng Q. Shao M, et al. J Asthma. 2025 Mar;62(3):376-385. doi: 10.1080/02770903.2024.2415544. Epub 2025 Jan 2. J Asthma. 2025. PMID: 39394937
The meta-analysis of controlled trials showed that the SMD of NSS in the group of montelukast combined with levocetirizine was -2.56 (95%CI: -2.77 to -2.35). The result indicated that compared with the control group, the combination of montelukast with levocetirizine …
The meta-analysis of controlled trials showed that the SMD of NSS in the group of montelukast combined with levocetirizine was -2.56 …
Efficacy and safety of bilastine vs. levocetirizine for the treatment of chronic idiopathic urticaria: A multicenter, double-blind, double-dummy, phase III, non-inferiority, randomized clinical trial.
Chen X, Han X, Cheng B, Li H, Liu L, Geng S, Li L, Li J, Guo Q, Zhang G, Fang H, Zhang J. Chen X, et al. Chin Med J (Engl). 2024 Jun 20;137(12):1480-1482. doi: 10.1097/CM9.0000000000003071. Epub 2024 Apr 1. Chin Med J (Engl). 2024. PMID: 38557589 Free PMC article. Clinical Trial. No abstract available.
Sedative Effects of Levocetirizine: A Systematic Review and Meta-Analysis of Randomized Controlled Studies.
Snidvongs K, Seresirikachorn K, Khattiyawittayakun L, Chitsuthipakorn W. Snidvongs K, et al. Drugs. 2017 Feb;77(2):175-186. doi: 10.1007/s40265-016-0682-0. Drugs. 2017. PMID: 28070872
INTRODUCTION: As a substrate of P-glycoprotein, levocetirizine should not cause sedative effects. However, while cetirizine, a mixture of levocetirizine and dextrocetirizine, can slightly penetrate the blood brain barrier, the sedative effects of levocetirizine …
INTRODUCTION: As a substrate of P-glycoprotein, levocetirizine should not cause sedative effects. However, while cetirizine, a mixtur …
A treatment for allergic rhinitis: a view on the role of levocetirizine.
Holgate S, Powell R, Jenkins M, Ali O. Holgate S, et al. Curr Med Res Opin. 2005 Jul;21(7):1099-106. doi: 10.1185/030079905X53298. Curr Med Res Opin. 2005. PMID: 16004679 Review.
SCOPE: The panel considered available evidence and focused on four published studies on the second-generation antihistamine, levocetirizine. Three of these studies explored the clinical impact of levocetirizine in a broad range of different clinical settings. ...The …
SCOPE: The panel considered available evidence and focused on four published studies on the second-generation antihistamine, levocetirizi …
Efficacy of different oral H1 antihistamine treatments on allergic rhinitis: a systematic review and network meta-analysis of randomized controlled trials.
Hong D, Weng J, Ye M, Liu Y. Hong D, et al. Braz J Otorhinolaryngol. 2023 Jul-Aug;89(4):101272. doi: 10.1016/j.bjorl.2023.03.009. Epub 2023 Apr 7. Braz J Otorhinolaryngol. 2023. PMID: 37271114 Free PMC article.
According to the results of SUCRA, rupatadine 20 mg and rupatadine 10 mg were ranked relatively high in reductions of total symptom score (SUCRA: 99.7%, 76.3%), nasal congestion score (SUCRA: 96.4%, 76.4%), rhinorrhea score (SUCRA: 96.6%, 74.6%) and ocular symptom score (SUCRA: 9 …
According to the results of SUCRA, rupatadine 20 mg and rupatadine 10 mg were ranked relatively high in reductions of total symptom score (S …
Levocetirizine Oral Disintegrating Tablet: A Randomized Open-Label Crossover Bioequivalence Study in Healthy Japanese Volunteers.
Ino H, Shiramoto M, Eto T, Haranaka M, Irie S, Terao T, Ogura H, Wakamatsu A, Hoyano K, Nakano A. Ino H, et al. Clin Pharmacol Drug Dev. 2020 Oct;9(7):805-812. doi: 10.1002/cpdd.791. Epub 2020 Mar 20. Clin Pharmacol Drug Dev. 2020. PMID: 32196954 Free PMC article. Clinical Trial.
Levocetirizine is classified as a second-generation antihistamine. Levocetirizine is available for the treatment of allergic disorders such as allergic rhinitis and chronic idiopathic urticaria. ...Bioequivalence was demonstrated between levocetirizine IRT 5 …
Levocetirizine is classified as a second-generation antihistamine. Levocetirizine is available for the treatment of allergic d …
Bioequivalence of Levocetirizine Hydrochloride Granules (Kangzhitai) in Healthy Subjects.
Xiang H, Yang G, Tan H. Xiang H, et al. Altern Ther Health Med. 2023 May;29(4):205-209. Altern Ther Health Med. 2023. PMID: 36947656 Free article. Clinical Trial.
As a high-efficiency non-sedating antihistamine, levocetirizine hydrochloride has been widely used in the clinical treatment of skin, respiratory, and eye allergies. However, the bioavailability of levocetirizine hydrochloride granules remains to be determined. The …
As a high-efficiency non-sedating antihistamine, levocetirizine hydrochloride has been widely used in the clinical treatment of skin, …
Comparative Efficacy of Montelukast-Levocetirizine Combination Therapy versus Monotherapy in Allergic Rhinitis: A Systematic Review and Meta-Analysis.
Kim JS, Stybayeva G, Hwang SH. Kim JS, et al. Int Arch Allergy Immunol. 2026;187(4):392-405. doi: 10.1159/000547410. Epub 2025 Jul 15. Int Arch Allergy Immunol. 2026. PMID: 40664175 Free PMC article.
This meta-analysis assessed the efficacy of montelukast combined with levocetirizine in patients with AR by directly comparing the combination therapy with each monotherapy and evaluating individual symptom domains. ...TEAE rates were similar across groups (OR [95% CI]: 1. …
This meta-analysis assessed the efficacy of montelukast combined with levocetirizine in patients with AR by directly comparing the co …
The effectiveness of levocetirizine in comparison with loratadine in treatment of allergic rhinitis--a meta-analysis.
Mösges R, König V, Köberlein J. Mösges R, et al. Allergol Int. 2011 Dec;60(4):541-6. doi: 10.2332/allergolint.10-OA-0300. Epub 2011 Sep 25. Allergol Int. 2011. PMID: 21918368 Free article.
The goal of this investigation is to make an indirect comparison between loratadine, an oral antihistamine available over-the-counter (OTC) in the USA, and the more modern antihistamine levocetirizine. Only double-blind, placebo-controlled (DBPC) studies involving monother …
The goal of this investigation is to make an indirect comparison between loratadine, an oral antihistamine available over-the-counter (OTC) …
Improving SAR symptoms with levocetirizine: evaluating active and placebo effects in pollen challenge vs. natural exposure studies.
Boev R, Song D, Bedenbaugh A, Haeusler JM. Boev R, et al. Curr Med Res Opin. 2011 Jan;27(1):107-14. doi: 10.1185/03007995.2010.537319. Epub 2010 Nov 24. Curr Med Res Opin. 2011. PMID: 21091390
RESULTS: Data from 3640 subjects were analysed (n = 2174 for levocetirizine, n = 1466 for placebo). The overall results confirmed the efficacy of levocetirizine 5 mg, with an approximately 40% symptom score improvement from baseline, in both the EE and NE groups. . …
RESULTS: Data from 3640 subjects were analysed (n = 2174 for levocetirizine, n = 1466 for placebo). The overall results confirmed the …
129 results