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Did you mean levothyroxine bioequivalence genetic (1 results)?
Bioequivalence studies for levothyroxine.
Bolton S. Bolton S. AAPS J. 2005 Mar 30;7(1):E47-53. doi: 10.1208/aapsj070106. AAPS J. 2005. PMID: 16146349 Free PMC article. Review.
The Food and Drug Administration (FDA) Guidance for Bioavailability and Bioequivalence Studies for Levothyroxine has been challenged by companies that manufacture brand-name products. ...In particular, they conclude that products that have a potency differing by 12. …
The Food and Drug Administration (FDA) Guidance for Bioavailability and Bioequivalence Studies for Levothyroxine has been chal …
Bioequivalence of generic and brand-name levothyroxine products in the treatment of hypothyroidism.
Dong BJ, Hauck WW, Gambertoglio JG, Gee L, White JR, Bubp JL, Greenspan FS. Dong BJ, et al. JAMA. 1997 Apr 16;277(15):1205-13. JAMA. 1997. PMID: 9103344 Clinical Trial.
OBJECTIVE: To compare relative bioavailability of Synthroid, Levoxine (Levoxine has been renamed Levoxyl), and 2 generic levothyroxine sodium preparations. DESIGN: Single-blind (primary investigators blinded), randomized, 4-way crossover trial. ...CONCLUSIONS: The 4 …
OBJECTIVE: To compare relative bioavailability of Synthroid, Levoxine (Levoxine has been renamed Levoxyl), and 2 generic levothyro …
Thyroid storm.
Rennie D. Rennie D. JAMA. 1997 Apr 16;277(15):1238-43. JAMA. 1997. PMID: 9103350 No abstract available.
Bioequivalence of generic preparations of levothyroxine.
Toft A. Toft A. Clin Endocrinol (Oxf). 2009 Oct;71(4):603; author reply 603-4. doi: 10.1111/j.1365-2265.2009.03647.x. Epub 2009 Jun 8. Clin Endocrinol (Oxf). 2009. PMID: 19508682 No abstract available.
Levothyroxine Formulations: Pharmacological and Clinical Implications of Generic Substitution.
Benvenga S, Carlé A. Benvenga S, et al. Adv Ther. 2019 Sep;36(Suppl 2):59-71. doi: 10.1007/s12325-019-01079-1. Epub 2019 Sep 4. Adv Ther. 2019. PMID: 31485974 Free PMC article. Review.
Multiple brand-name and generic LT4 tablets are available. In the US, the Food and Drug Administration (FDA) has developed a protocol for establishing bioequivalence of LT4 formulations based on serum thyroxine (T4) levels after a single oral dose administere …
Multiple brand-name and generic LT4 tablets are available. In the US, the Food and Drug Administration (FDA) has developed a protocol …
Current methodology to assess bioequivalence of levothyroxine sodium products is inadequate.
Blakesley VA. Blakesley VA. AAPS J. 2005 Mar 30;7(1):E42-6. doi: 10.1208/aapsj070105. AAPS J. 2005. PMID: 16146348 Free PMC article. Review.
Levothyroxine sodium is a drug with a narrow therapeutic index for which an individual patient must have his or her dose carefully titrated to achieve the necessary therapeutic effect. In addition, exogenous levothyroxine cannot be distinguished from t …
Levothyroxine sodium is a drug with a narrow therapeutic index for which an individual patient must have his or her dose caref …
51 results