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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1970 2
1971 2
1972 2
1973 2
1974 1
1976 3
1977 3
1979 9
1980 6
1981 7
1982 5
1983 3
1984 8
1985 8
1986 14
1987 14
1988 14
1989 9
1990 13
1991 21
1992 20
1993 23
1994 26
1995 27
1996 42
1997 34
1998 39
1999 25
2000 16
2001 31
2002 36
2003 41
2004 33
2005 39
2006 48
2007 43
2008 38
2009 45
2010 56
2011 36
2012 41
2013 47
2014 38
2015 41
2016 39
2017 52
2018 41
2019 42
2020 54
2021 59
2022 39
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1,226 results
Results by year
Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism.
Shakir MKM, Brooks DI, McAninch EA, Fonseca TL, Mai VQ, Bianco AC, Hoang TD. Shakir MKM, et al. J Clin Endocrinol Metab. 2021 Oct 21;106(11):e4400-e4413. doi: 10.1210/clinem/dgab478. J Clin Endocrinol Metab. 2021. PMID: 34185829 Free PMC article. Clinical Trial.
INTRODUCTION: Studies comparing levothyroxine (LT4) therapy with LT4 + liothyronine (LT3) or desiccated thyroid extract (DTE) did not detect consistent superiority of either treatment. ...
INTRODUCTION: Studies comparing levothyroxine (LT4) therapy with LT4 + liothyronine (LT3) or desiccated thyroid extract (DTE) did not …
Subclinical Hypothyroidism in Pregnancy: A Systematic Review and Meta-Analysis.
Maraka S, Ospina NM, O'Keeffe DT, Espinosa De Ycaza AE, Gionfriddo MR, Erwin PJ, Coddington CC 3rd, Stan MN, Murad MH, Montori VM. Maraka S, et al. Thyroid. 2016 Apr;26(4):580-90. doi: 10.1089/thy.2015.0418. Epub 2016 Mar 3. Thyroid. 2016. PMID: 26837268 Free PMC article. Review.
BACKGROUND: The impact of subclinical hypothyroidism (SCH) and of levothyroxine replacement in pregnant women with SCH is unclear. The aims of this study were to assess (i) the impact of SCH during pregnancy on maternal and neonatal outcomes, and (ii) the effect of levo
BACKGROUND: The impact of subclinical hypothyroidism (SCH) and of levothyroxine replacement in pregnant women with SCH is unclear. Th …
Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism: An Ancillary Study of a Randomized Clinical Trial.
Wildisen L, Feller M, Del Giovane C, Moutzouri E, Du Puy RS, Mooijaart SP, Collet TH, Poortvliet RKE, Kearney P, Quinn TJ, Klöppel S, Bauer DC, Peeters RP, Westendorp R, Aujesky D, Gussekloo J, Rodondi N. Wildisen L, et al. JAMA Netw Open. 2021 Feb 1;4(2):e2036645. doi: 10.1001/jamanetworkopen.2020.36645. JAMA Netw Open. 2021. PMID: 33566107 Free PMC article. Clinical Trial.
At baseline, the mean (SD) GDS-15 score was 1.26 (1.85) in the levothyroxine group and 0.96 (1.58) in the placebo group. The mean (SD) GDS-15 score at 12 months was 1.39 (2.13) in the levothyroxine and 1.07 (1.67) in the placebo group with an adjusted between-group …
At baseline, the mean (SD) GDS-15 score was 1.26 (1.85) in the levothyroxine group and 0.96 (1.58) in the placebo group. The mean (SD …
Combined therapy with levothyroxine and liothyronine for hypothyroidism.
Fischman A, Domínguez JM. Fischman A, et al. Medwave. 2018 Dec 14;18(8):e7376. doi: 10.5867/medwave.2018.08.7375. Medwave. 2018. PMID: 30550536 English, Spanish.
INTRODUCTION: The usual supplementation for hypothyroidism is based on monotherapy with levothyroxine. However, some patients persist with symptoms attributable to the deficit of thyroid hormone. It has been suggested that the a combined treatment with liothyronine and …
INTRODUCTION: The usual supplementation for hypothyroidism is based on monotherapy with levothyroxine. However, some patients persist …
Effect of Levothyroxine on Miscarriage Among Women With Normal Thyroid Function and Thyroid Autoimmunity Undergoing In Vitro Fertilization and Embryo Transfer: A Randomized Clinical Trial.
Wang H, Gao H, Chi H, Zeng L, Xiao W, Wang Y, Li R, Liu P, Wang C, Tian Q, Zhou Z, Yang J, Liu Y, Wei R, Mol BWJ, Hong T, Qiao J. Wang H, et al. JAMA. 2017 Dec 12;318(22):2190-2198. doi: 10.1001/jama.2017.18249. JAMA. 2017. PMID: 29234808 Clinical Trial.
The women in the control group (n = 300) did not receive levothyroxine. All participants received the same IVF-ET and follow-up protocols. ...CONCLUSIONS AND RELEVANCE: Among women in China who had intact thyroid function and tested positive for antithyroperoxidase antibod …
The women in the control group (n = 300) did not receive levothyroxine. All participants received the same IVF-ET and follow-up proto …
Are multisource levothyroxine sodium tablets marketed in Egypt interchangeable?
Abou-Taleb BA, Bondok M, Nounou MI, Khalafallah N, Khalil S. Abou-Taleb BA, et al. Ann Endocrinol (Paris). 2018 Feb;79(1):23-29. doi: 10.1016/j.ando.2017.10.002. Epub 2017 Dec 27. Ann Endocrinol (Paris). 2018. PMID: 29289332 Clinical Trial.
A clinical study was initiated in response to patients' complaints, supported by the treating physicians, of suspected differences in efficacy among multisource levothyroxine sodium tablets marketed in Egypt. The study design was a multiple dose (100mug levothyro
A clinical study was initiated in response to patients' complaints, supported by the treating physicians, of suspected differences in effica …
Pharmacokinetics and Comparative Bioavailability of a Levothyroxine Sodium Oral Solution and Soft Capsule.
Tanguay M, Girard J, Scarsi C, Mautone G, Larouche R. Tanguay M, et al. Clin Pharmacol Drug Dev. 2019 May;8(4):521-528. doi: 10.1002/cpdd.608. Epub 2018 Aug 28. Clin Pharmacol Drug Dev. 2019. PMID: 30153382 Free PMC article. Clinical Trial.
A new formulation of levothyroxine sodium has been developed in the form of an oral solution contained in unit-dose ampules. A study has been conducted to compare the bioavailability of levothyroxine sodium oral solution and levothyroxine sod
A new formulation of levothyroxine sodium has been developed in the form of an oral solution contained in unit-dose ampules. A …
Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.
Stott DJ, Rodondi N, Kearney PM, Ford I, Westendorp RGJ, Mooijaart SP, Sattar N, Aubert CE, Aujesky D, Bauer DC, Baumgartner C, Blum MR, Browne JP, Byrne S, Collet TH, Dekkers OM, den Elzen WPJ, Du Puy RS, Ellis G, Feller M, Floriani C, Hendry K, Hurley C, Jukema JW, Kean S, Kelly M, Krebs D, Langhorne P, McCarthy G, McCarthy V, McConnachie A, McDade M, Messow M, O'Flynn A, O'Riordan D, Poortvliet RKE, Quinn TJ, Russell A, Sinnott C, Smit JWA, Van Dorland HA, Walsh KA, Walsh EK, Watt T, Wilson R, Gussekloo J; TRUST Study Group. Stott DJ, et al. N Engl J Med. 2017 Jun 29;376(26):2534-2544. doi: 10.1056/NEJMoa1603825. Epub 2017 Apr 3. N Engl J Med. 2017. PMID: 28402245 Free article. Clinical Trial.
BACKGROUND: The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed to determine whether levothyroxine provided clinical benefits in older persons with this condition. ...CONCLUSIONS: Levothyroxine provided no apparent benefits …
BACKGROUND: The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed to determine whether levothyro
Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study.
Hoang TD, Olsen CH, Mai VQ, Clyde PW, Shakir MK. Hoang TD, et al. J Clin Endocrinol Metab. 2013 May;98(5):1982-90. doi: 10.1210/jc.2012-4107. Epub 2013 Mar 28. J Clin Endocrinol Metab. 2013. PMID: 23539727 Clinical Trial.
CONTEXT: Patients previously treated with desiccated thyroid extract (DTE), when being switched to levothyroxine (L-T4), occasionally did not feel as well despite adequate dosing based on serum TSH levels. ...
CONTEXT: Patients previously treated with desiccated thyroid extract (DTE), when being switched to levothyroxine (L-T4), occasionally …
Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis.
Feller M, Snel M, Moutzouri E, Bauer DC, de Montmollin M, Aujesky D, Ford I, Gussekloo J, Kearney PM, Mooijaart S, Quinn T, Stott D, Westendorp R, Rodondi N, Dekkers OM. Feller M, et al. JAMA. 2018 Oct 2;320(13):1349-1359. doi: 10.1001/jama.2018.13770. JAMA. 2018. PMID: 30285179 Free PMC article. Review.
1,226 results