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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1970 2
1971 2
1972 2
1973 2
1974 1
1976 3
1977 3
1979 9
1980 6
1981 7
1982 5
1983 3
1984 8
1985 8
1986 14
1987 14
1988 14
1989 9
1990 13
1991 21
1992 20
1993 23
1994 26
1995 27
1996 42
1997 34
1998 39
1999 25
2000 16
2001 31
2002 36
2003 41
2004 33
2005 39
2006 48
2007 43
2008 38
2009 45
2010 56
2011 36
2012 41
2013 47
2014 38
2015 41
2016 39
2017 52
2018 41
2019 42
2020 53
2021 59
2022 63
2023 50
2024 13

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1,301 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism.
Shakir MKM, Brooks DI, McAninch EA, Fonseca TL, Mai VQ, Bianco AC, Hoang TD. Shakir MKM, et al. J Clin Endocrinol Metab. 2021 Oct 21;106(11):e4400-e4413. doi: 10.1210/clinem/dgab478. J Clin Endocrinol Metab. 2021. PMID: 34185829 Free PMC article. Clinical Trial.
INTRODUCTION: Studies comparing levothyroxine (LT4) therapy with LT4 + liothyronine (LT3) or desiccated thyroid extract (DTE) did not detect consistent superiority of either treatment. ...
INTRODUCTION: Studies comparing levothyroxine (LT4) therapy with LT4 + liothyronine (LT3) or desiccated thyroid extract (DTE) did not …
Subclinical Hypothyroidism in Pregnancy: A Systematic Review and Meta-Analysis.
Maraka S, Ospina NM, O'Keeffe DT, Espinosa De Ycaza AE, Gionfriddo MR, Erwin PJ, Coddington CC 3rd, Stan MN, Murad MH, Montori VM. Maraka S, et al. Thyroid. 2016 Apr;26(4):580-90. doi: 10.1089/thy.2015.0418. Epub 2016 Mar 3. Thyroid. 2016. PMID: 26837268 Free PMC article. Review.
BACKGROUND: The impact of subclinical hypothyroidism (SCH) and of levothyroxine replacement in pregnant women with SCH is unclear. The aims of this study were to assess (i) the impact of SCH during pregnancy on maternal and neonatal outcomes, and (ii) the effect of levo
BACKGROUND: The impact of subclinical hypothyroidism (SCH) and of levothyroxine replacement in pregnant women with SCH is unclear. Th …
Effect of initial levothyroxine dose on neurodevelopmental and growth outcomes in children with congenital hypothyroidism.
Esposito A, Vigone MC, Polizzi M, Wasniewska MG, Cassio A, Mussa A, Gastaldi R, Di Mase R, Vincenzi G, Pozzi C, Peroni E, Bravaccio C, Capalbo D, Bruzzese D, Salerno M. Esposito A, et al. Front Endocrinol (Lausanne). 2022 Sep 5;13:923448. doi: 10.3389/fendo.2022.923448. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36133316 Free PMC article. Clinical Trial.
OBJECTIVES: We designed a multicentre open prospective randomized trial to evaluate the risk-benefit profile of two different initial treatment schemes with levothyroxine (L-T4), 10-12.5 mug/kg/day vs 12.6-15 mug/kg/day, on growth and neurodevelopmental outcomes in childre …
OBJECTIVES: We designed a multicentre open prospective randomized trial to evaluate the risk-benefit profile of two different initial treatm …
Are multisource levothyroxine sodium tablets marketed in Egypt interchangeable?
Abou-Taleb BA, Bondok M, Nounou MI, Khalafallah N, Khalil S. Abou-Taleb BA, et al. Ann Endocrinol (Paris). 2018 Feb;79(1):23-29. doi: 10.1016/j.ando.2017.10.002. Epub 2017 Dec 27. Ann Endocrinol (Paris). 2018. PMID: 29289332 Clinical Trial.
A clinical study was initiated in response to patients' complaints, supported by the treating physicians, of suspected differences in efficacy among multisource levothyroxine sodium tablets marketed in Egypt. The study design was a multiple dose (100mug levothyro
A clinical study was initiated in response to patients' complaints, supported by the treating physicians, of suspected differences in effica …
Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.
Stott DJ, Rodondi N, Kearney PM, Ford I, Westendorp RGJ, Mooijaart SP, Sattar N, Aubert CE, Aujesky D, Bauer DC, Baumgartner C, Blum MR, Browne JP, Byrne S, Collet TH, Dekkers OM, den Elzen WPJ, Du Puy RS, Ellis G, Feller M, Floriani C, Hendry K, Hurley C, Jukema JW, Kean S, Kelly M, Krebs D, Langhorne P, McCarthy G, McCarthy V, McConnachie A, McDade M, Messow M, O'Flynn A, O'Riordan D, Poortvliet RKE, Quinn TJ, Russell A, Sinnott C, Smit JWA, Van Dorland HA, Walsh KA, Walsh EK, Watt T, Wilson R, Gussekloo J; TRUST Study Group. Stott DJ, et al. N Engl J Med. 2017 Jun 29;376(26):2534-2544. doi: 10.1056/NEJMoa1603825. Epub 2017 Apr 3. N Engl J Med. 2017. PMID: 28402245 Free article. Clinical Trial.
BACKGROUND: The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed to determine whether levothyroxine provided clinical benefits in older persons with this condition. ...CONCLUSIONS: Levothyroxine provided no apparent benefits …
BACKGROUND: The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed to determine whether levothyro
Pharmacokinetics and Comparative Bioavailability of a Levothyroxine Sodium Oral Solution and Soft Capsule.
Tanguay M, Girard J, Scarsi C, Mautone G, Larouche R. Tanguay M, et al. Clin Pharmacol Drug Dev. 2019 May;8(4):521-528. doi: 10.1002/cpdd.608. Epub 2018 Aug 28. Clin Pharmacol Drug Dev. 2019. PMID: 30153382 Free PMC article. Clinical Trial.
A new formulation of levothyroxine sodium has been developed in the form of an oral solution contained in unit-dose ampules. A study has been conducted to compare the bioavailability of levothyroxine sodium oral solution and levothyroxine sod
A new formulation of levothyroxine sodium has been developed in the form of an oral solution contained in unit-dose ampules. A …
Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy.
Casey BM, Thom EA, Peaceman AM, Varner MW, Sorokin Y, Hirtz DG, Reddy UM, Wapner RJ, Thorp JM Jr, Saade G, Tita AT, Rouse DJ, Sibai B, Iams JD, Mercer BM, Tolosa J, Caritis SN, VanDorsten JP; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal–Fetal Medicine Units Network. Casey BM, et al. N Engl J Med. 2017 Mar 2;376(9):815-825. doi: 10.1056/NEJMoa1606205. N Engl J Med. 2017. PMID: 28249134 Free PMC article. Clinical Trial.
In separate trials for the two conditions, women were randomly assigned to receive levothyroxine or placebo. Thyroid function was assessed monthly, and the levothyroxine dose was adjusted to attain a normal thyrotropin or free T(4) level (depending on the trial), wi …
In separate trials for the two conditions, women were randomly assigned to receive levothyroxine or placebo. Thyroid function was ass …
Pharmacokinetics of coadministration of levothyroxine sodium and alendronate sodium new effervescent formulation.
Bone HG, Walter MA, Hurley ME, Epstein S. Bone HG, et al. Osteoporos Int. 2017 May;28(5):1745-1752. doi: 10.1007/s00198-017-3941-3. Epub 2017 Feb 16. Osteoporos Int. 2017. PMID: 28204953 Free PMC article. Clinical Trial.
No clinically important pharmacokinetic interference of alendronate occurred between a new effervescent formulation of alendronate and levothyroxine when coadministered. The combination does not materially affect levothyroxine absorption. INTRODUCTION: Concurrent tr …
No clinically important pharmacokinetic interference of alendronate occurred between a new effervescent formulation of alendronate and le
Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis.
Feller M, Snel M, Moutzouri E, Bauer DC, de Montmollin M, Aujesky D, Ford I, Gussekloo J, Kearney PM, Mooijaart S, Quinn T, Stott D, Westendorp R, Rodondi N, Dekkers OM. Feller M, et al. JAMA. 2018 Oct 2;320(13):1349-1359. doi: 10.1001/jama.2018.13770. JAMA. 2018. PMID: 30285179 Free PMC article. Review.
Systematic review and meta-analysis of the efficacy and pregnancy outcomes of levothyroxine sodium tablet administration in pregnant women complicated with hypothyroidism.
Geng X, Chen Y, Wang W, Ma J, Wu W, Li N, Sun C. Geng X, et al. Ann Palliat Med. 2022 Apr;11(4):1441-1452. doi: 10.21037/apm-22-269. Ann Palliat Med. 2022. PMID: 35523752 Free article.
DISCUSSION: Levothyroxine sodium in the treatment of SCH can significantly reduce the incidence of premature birth, miscarriage, postpartum hemorrhage, and low birth weight infants. Due to the limited number of included studies, it remained to be further verified wh …
DISCUSSION: Levothyroxine sodium in the treatment of SCH can significantly reduce the incidence of premature birth, miscarriag …
1,301 results