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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1947 1
1948 1
1949 5
1951 7
1952 13
1953 31
1954 28
1955 24
1956 36
1957 31
1958 47
1959 32
1960 29
1961 31
1962 41
1963 39
1964 77
1965 74
1966 67
1967 101
1968 142
1969 161
1970 184
1971 185
1972 225
1973 243
1974 268
1975 262
1976 199
1977 228
1978 227
1979 258
1980 253
1981 251
1982 283
1983 256
1984 301
1985 321
1986 308
1987 311
1988 328
1989 293
1990 344
1991 348
1992 336
1993 365
1994 336
1995 341
1996 331
1997 367
1998 332
1999 343
2000 360
2001 353
2002 391
2003 413
2004 457
2005 470
2006 487
2007 484
2008 503
2009 483
2010 521
2011 499
2012 520
2013 526
2014 554
2015 560
2016 537
2017 561
2018 585
2019 549
2020 618
2021 650
2022 576
2023 518
2024 566
2025 707
2026 295

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22,053 results

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Page 1
Levothyroxine Therapy in Gastric Malabsorptive Disorders.
Virili C, Brusca N, Capriello S, Centanni M. Virili C, et al. Front Endocrinol (Lausanne). 2021 Jan 28;11:621616. doi: 10.3389/fendo.2020.621616. eCollection 2020. Front Endocrinol (Lausanne). 2021. PMID: 33584549 Free PMC article. Review.
Oral levothyroxine sodium is absorbed in the small intestine, mainly in the jejunum and the ileum being lower the absorption rate at duodenal level. ...However, several evidence confirm the key role of the stomach as a prerequisite for an efficient absorption of oral le …
Oral levothyroxine sodium is absorbed in the small intestine, mainly in the jejunum and the ileum being lower the absorption rate at …
Editorial: Levothyroxine Therapy in Patients With Hypothyroidism.
Antonelli A, Wartofsky L, Miccoli P. Antonelli A, et al. Front Endocrinol (Lausanne). 2021 Jul 20;12:734895. doi: 10.3389/fendo.2021.734895. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34354674 Free PMC article. No abstract available.
Levothyroxine therapy in thyroidectomized patients: ongoing challenges and controversies.
Rossi L, Paternoster M, Cammarata M, Bakkar S, Miccoli P. Rossi L, et al. Front Endocrinol (Lausanne). 2025 May 26;16:1582734. doi: 10.3389/fendo.2025.1582734. eCollection 2025. Front Endocrinol (Lausanne). 2025. PMID: 40491597 Free PMC article. Review.
This mini-review provides an update on the challenges and controversies surrounding levothyroxine therapy in thyroidectomized patients, following an extensive review on dosing strategies and available formulations. Despite efforts to establish an ideal dosage adjust …
This mini-review provides an update on the challenges and controversies surrounding levothyroxine therapy in thyroidectomized …
Levothyroxine Dose Adjustment to Optimise Therapy Throughout a Patient's Lifetime.
Duntas LH, Jonklaas J. Duntas LH, et al. Adv Ther. 2019 Sep;36(Suppl 2):30-46. doi: 10.1007/s12325-019-01078-2. Epub 2019 Sep 4. Adv Ther. 2019. PMID: 31485977 Free PMC article. Review.
Levothyroxine is the standard therapy for patients with hypothyroidism, a condition that affects up to 5% of people worldwide. While levothyroxine therapy has substantially improved the lives of millions of hypothyroid patients since its introduction i …
Levothyroxine is the standard therapy for patients with hypothyroidism, a condition that affects up to 5% of people worldwide. …
Levothyroxine Sodium - Thyroid Hormone Replacement Therapy for Hypothyroidism: A Review of Patent Literature.
Upadhyay U, Vora PA, Patel R, Prajapati B. Upadhyay U, et al. Recent Pat Biotechnol. 2023;17(3):245-256. doi: 10.2174/1872208317666221212124113. Recent Pat Biotechnol. 2023. PMID: 36515027 Review.
BACKGROUND: Levothyroxine Sodium is a thyroid hormone replacement therapy for Hypothyroidism. Levothyroxine Sodium is approved to treat Hypothyroidisim, to suppress thyroid hormone release from cancerous thyroid nodules, and to prevent the growth of goiters. …
BACKGROUND: Levothyroxine Sodium is a thyroid hormone replacement therapy for Hypothyroidism. Levothyroxine Sodium is a …
Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement.
Jonklaas J, Bianco AC, Bauer AJ, Burman KD, Cappola AR, Celi FS, Cooper DS, Kim BW, Peeters RP, Rosenthal MS, Sawka AM; American Thyroid Association Task Force on Thyroid Hormone Replacement. Jonklaas J, et al. Thyroid. 2014 Dec;24(12):1670-751. doi: 10.1089/thy.2014.0028. Thyroid. 2014. PMID: 25266247 Free PMC article.
BACKGROUND: A number of recent advances in our understanding of thyroid physiology may shed light on why some patients feel unwell while taking levothyroxine monotherapy. The purpose of this task force was to review the goals of levothyroxine therapy, the opt …
BACKGROUND: A number of recent advances in our understanding of thyroid physiology may shed light on why some patients feel unwell while tak …
Oral levothyroxine therapy postbariatric surgery: Biopharmaceutical aspects and clinical effects.
Azran C, Porat D, Fine-Shamir N, Hanhan N, Dahan A. Azran C, et al. Surg Obes Relat Dis. 2019 Feb;15(2):333-341. doi: 10.1016/j.soard.2019.01.001. Epub 2019 Jan 10. Surg Obes Relat Dis. 2019. PMID: 30704913
OBJECTIVE: The purpose of this work was to provide a mechanistic overview of levothyroxine absorption, and to thoroughly analyze the expected effects of bariatric surgery on oral levothyroxine therapy. ...RESULTS: Different mechanisms may support opposing tre …
OBJECTIVE: The purpose of this work was to provide a mechanistic overview of levothyroxine absorption, and to thoroughly analyze the …
Hypothyroidism: Diagnosis and Treatment.
Wilson SA, Stem LA, Bruehlman RD. Wilson SA, et al. Am Fam Physician. 2021 May 15;103(10):605-613. Am Fam Physician. 2021. PMID: 33983002 Free article.
The signs and symptoms that suggest thyroid dysfunction are nonspecific and nondiagnostic, especially early in disease presentation; therefore, a diagnosis is based on blood levels of thyroid-stimulating hormone and free thyroxine. There is no evidence that population scre …
The signs and symptoms that suggest thyroid dysfunction are nonspecific and nondiagnostic, especially early in disease presentation; therefo …
Combined therapy with levothyroxine and liothyronine for hypothyroidism.
Fischman A, Domínguez JM. Fischman A, et al. Medwave. 2018 Dec 14;18(8):e7376. doi: 10.5867/medwave.2018.08.7375. Medwave. 2018. PMID: 30550536 English, Spanish.
INTRODUCTION: The usual supplementation for hypothyroidism is based on monotherapy with levothyroxine. However, some patients persist with symptoms attributable to the deficit of thyroid hormone. It has been suggested that the a combined treatment with liothyronine and …
INTRODUCTION: The usual supplementation for hypothyroidism is based on monotherapy with levothyroxine. However, some patients persist …
Subclinical Hypothyroidism: A Review.
Biondi B, Cappola AR, Cooper DS. Biondi B, et al. JAMA. 2019 Jul 9;322(2):153-160. doi: 10.1001/jama.2019.9052. JAMA. 2019. PMID: 31287527 Review.
In the absence of large randomized trials showing benefit from levothyroxine therapy, the rationale for treatment is based on the potential for decreasing the risk of adverse cardiovascular events and the possibility of preventing progression to overt hypothyroidism …
In the absence of large randomized trials showing benefit from levothyroxine therapy, the rationale for treatment is based on …
22,053 results
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