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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1953 1
1955 2
1956 2
1957 3
1958 2
1959 1
1963 8
1964 29
1965 23
1966 25
1967 25
1968 33
1969 44
1970 27
1971 33
1972 36
1973 23
1974 49
1975 45
1976 27
1977 28
1978 30
1979 28
1980 31
1981 28
1982 34
1983 26
1984 37
1985 46
1986 42
1987 51
1988 47
1989 76
1990 92
1991 81
1992 70
1993 84
1994 81
1995 71
1996 73
1997 85
1998 94
1999 75
2000 77
2001 77
2002 65
2003 67
2004 76
2005 71
2006 80
2007 79
2008 95
2009 93
2010 95
2011 97
2012 107
2013 102
2014 100
2015 103
2016 102
2017 94
2018 105
2019 119
2020 131
2021 149
2022 98
2023 97
2024 106
2025 114
2026 70

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4,046 results

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Page 1
Pharmacokinetics and metabolism of lidocaine HCl 2% with epinephrine in horses following a palmar digital nerve block.
Knych HK, Katzman S, McKemie DS, Arthur RM, Blea J. Knych HK, et al. BMC Vet Res. 2023 Oct 30;19(1):225. doi: 10.1186/s12917-023-03787-x. BMC Vet Res. 2023. PMID: 37904169 Free PMC article.
BACKGROUND: Lidocaine is a local anesthetic that is sometimes administered in combination with epinephrine. ...Twelve horses received a single administration of 1 mL of 2% lidocaine HCl (20 mg/horse) with epinephrine 1:100,000, over the palmar d …
BACKGROUND: Lidocaine is a local anesthetic that is sometimes administered in combination with epinephrine. ...Twelve horses r …
Epinephrine-Containing Lidocaine and Hematoma Risk After Image-Guided Core-Needle Breast Biopsy.
Davis EE, Mark S, Woodard GA, Tang F, Gellatly M, Hayward JH, Ray KM, Joe BN, Lee AY, Chung M. Davis EE, et al. J Breast Imaging. 2025 Dec 13;7(6):653-663. doi: 10.1093/jbi/wbaf026. J Breast Imaging. 2025. PMID: 40884447 Free article.
OBJECTIVE: To evaluate the risk of symptomatic hematomas in patients receiving epinephrine-containing lidocaine compared with lidocaine alone after core-needle breast biopsies (CNBBs). ...METHODS: A single-institution, retrospective review of all CNBBs perfor …
OBJECTIVE: To evaluate the risk of symptomatic hematomas in patients receiving epinephrine-containing lidocaine compared with …
Effects of lidocaine incorporation (without epinephrine) on pain and 2-week complications of botulinum toxin: a double-blind randomized placebo-controlled clinical trial.
Sarkarat F, Bagheri D, Kahali R, Fateh A, Rakhshan V. Sarkarat F, et al. Sci Rep. 2023 May 14;13(1):7812. doi: 10.1038/s41598-023-34973-4. Sci Rep. 2023. PMID: 37183235 Free PMC article. Clinical Trial.
In the 2 experimental subgroups, botulinum toxin was diluted with 2% lidocaine without adrenaline; in the 2 control subgroups, botulinum toxin was diluted with normal saline as a placebo. ...The mean SD pain levels in the subgroups 'Xeomin-Lidocaine (n = 61 …
In the 2 experimental subgroups, botulinum toxin was diluted with 2% lidocaine without adrenaline; in the 2 control subgroups, …
Topical anesthesia.
Keyes PD, Tallon JM, Rizos J. Keyes PD, et al. Can Fam Physician. 1998 Oct;44:2152-6. Can Fam Physician. 1998. PMID: 9805170 Free PMC article. Review.
QUALITY OF EVIDENCE: Five randomized controlled trials were retrieved that compared various topical anesthetics as well as topical anesthetics versus infiltrative anesthesia. MAIN FINDINGS: A combination of lidocaine, epinephrine, and tetracaine (LET) is currently t …
QUALITY OF EVIDENCE: Five randomized controlled trials were retrieved that compared various topical anesthetics as well as topical anestheti …
Safety of Prefilled Buffered Lidocaine Syringes With and Without Epinephrine.
Pate DA, Shimizu I, Akin R, Snodgrass K, Emrick A. Pate DA, et al. Dermatol Surg. 2016 Mar;42(3):361-5. doi: 10.1097/DSS.0000000000000624. Dermatol Surg. 2016. PMID: 26859654
BACKGROUND: Lidocaine is often used in conjunction with epinephrine and sodium bicarbonate for local anesthesia. ...METHODS: Syringes were filled with lidocaine 1%, lidocaine 1% with 1:100,000 epinephrine, lidocaine 1% with bicarbonate (1 …
BACKGROUND: Lidocaine is often used in conjunction with epinephrine and sodium bicarbonate for local anesthesia. ...METHODS: S …
Lidocaine and epinephrine levels in tumescent technique liposuction.
Burk RW 3rd, Guzman-Stein G, Vasconez LO. Burk RW 3rd, et al. Plast Reconstr Surg. 1996 Jun;97(7):1379-84. doi: 10.1097/00006534-199606000-00009. Plast Reconstr Surg. 1996. PMID: 8643720
The safety of lidocaine and epinephrine dosing was investigated in 10 patients undergoing tumescent technique liposuction alone and in 10 patients undergoing tumescent liposuction with concurrent facial and aesthetic breast surgery by determining serum lidocaine …
The safety of lidocaine and epinephrine dosing was investigated in 10 patients undergoing tumescent technique liposuction alon …
Pharmacokinetics of Single Dose Lidocaine and Epinephrine Following Iontophoresis of the Tympanic Membrane in a Double-Blinded Randomized Trial.
England LJ, Syms CA 3rd, York C. England LJ, et al. Otol Neurotol. 2021 Aug 1;42(7):1095-1103. doi: 10.1097/MAO.0000000000003128. Otol Neurotol. 2021. PMID: 33859140 Free PMC article. Clinical Trial.
RESULTS: Twenty-five subjects were treated with bilateral iontophoresis of either lidocaine and epinephrine (n = 15 subjects) or lidocaine alone (n = 10). Mean plasma epinephrine concentrations for both groups remained within the normal range for endog …
RESULTS: Twenty-five subjects were treated with bilateral iontophoresis of either lidocaine and epinephrine (n = 15 subjects) …
Stability of buffered lidocaine and epinephrine used for local anesthesia.
Larson PO, Ragi G, Swandby M, Darcey B, Polzin G, Carey P. Larson PO, et al. J Dermatol Surg Oncol. 1991 May;17(5):411-4. doi: 10.1111/j.1524-4725.1991.tb03975.x. J Dermatol Surg Oncol. 1991. PMID: 2030202
Reduced pain on injection of lidocaine and epinephrine buffered to a neutral pH was confirmed in 20 subjects (P less than .01). ...This permits batch buffering of lidocaine with epinephrine and storage for periods up to 2 weeks when properly refrigerat …
Reduced pain on injection of lidocaine and epinephrine buffered to a neutral pH was confirmed in 20 subjects (P less than .01) …
Onset, Duration, and Pain Score Obtained Using Lidocaine Mixed With Epinephrine and Bicarbonate in Plastic Surgery.
Kim H, Hwang K. Kim H, et al. J Craniofac Surg. 2020 Oct;31(7):1986-1990. doi: 10.1097/SCS.0000000000006627. J Craniofac Surg. 2020. PMID: 32604282
Therefore, 19 papers were analyzed.The mean time for the onset of maximum vasoconstriction caused by lidocaine with epinephrine (LE) ranged from 1.3 minutes (1:50,000 epinephrine) to 25.9 minutes (1:100,000 epinephrine). ...The mean duration of local a …
Therefore, 19 papers were analyzed.The mean time for the onset of maximum vasoconstriction caused by lidocaine with epinephrine …
4,046 results