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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin.

Philippaert K, Kalyaanamoorthy S, Fatehi M, Long W, Soni S, Byrne NJ, Barr A, Singh J, Wong J, Palechuk T, Schneider C, Darwesh AM, Maayah ZH, Seubert JM, Barakat K, Dyck JRB, Light PE. Philippaert K, et al. Among authors: light pe. Circulation. 2021 Jun;143(22):2188-2204. doi: 10.1161/CIRCULATIONAHA.121.053350. Epub 2021 Apr 9. Circulation. 2021. PMID: 33832341 Free PMC article.

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Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure.

Byrne NJ, Matsumura N, Maayah ZH, Ferdaoussi M, Takahara S, Darwesh AM, Levasseur JL, Jahng JWS, Vos D, Parajuli N, El-Kadi AOS, Braam B, Young ME, Verma S, Light PE, Sweeney G, Seubert JM, Dyck JRB. Byrne NJ, et al. Among authors: light pe. Circ Heart Fail. 2020 Jan;13(1):e006277. doi: 10.1161/CIRCHEARTFAILURE.119.006277. Epub 2020 Jan 20. Circ Heart Fail. 2020. PMID: 31957470

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Decoding the effects of SGLT2 inhibitors on cardiac arrhythmias in heart failure.

Light PE. Light PE. Eur Heart J. 2021 Sep 21;42(36):3739-3740. doi: 10.1093/eurheartj/ehab563. Eur Heart J. 2021. PMID: 34447979 No abstract available.

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Evidence for the existence and potential roles of intra-islet glucagon-like peptide-1.

Campbell SA, Johnson J, Light PE. Campbell SA, et al. Among authors: light pe. Islets. 2021 Mar 4;13(1-2):32-50. doi: 10.1080/19382014.2021.1889941. Epub 2021 Mar 16. Islets. 2021. PMID: 33724156 Free PMC article. Review.

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Resveratrol and derivatives for the treatment of atrial fibrillation.

Baczkó I, Light PE. Baczkó I, et al. Among authors: light pe. Ann N Y Acad Sci. 2015 Aug;1348(1):68-74. doi: 10.1111/nyas.12843. Epub 2015 Jul 23. Ann N Y Acad Sci. 2015. PMID: 26205342 Review.

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Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis.

Ondrusova K, Fatehi M, Barr A, Czarnecka Z, Long W, Suzuki K, Campbell S, Philippaert K, Hubert M, Tredget E, Kwan P, Touret N, Wabitsch M, Lee KY, Light PE. Ondrusova K, et al. Among authors: light pe. Sci Rep. 2017 Nov 27;7(1):16332. doi: 10.1038/s41598-017-16689-4. Sci Rep. 2017. PMID: 29180820 Free PMC article.

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Sarcolemmal KATP channel modulators and cardiac arrhythmias.

Baczkó I, Husti Z, Lang V, Leprán I, Light PE. Baczkó I, et al. Among authors: light pe. Curr Med Chem. 2011;18(24):3640-61. doi: 10.2174/092986711796642472. Curr Med Chem. 2011. PMID: 21774762 Review.

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Cardiovascular safety of sulphonylureas: over 40 years of continuous controversy without an answer.

Abdelmoneim AS, Eurich DT, Light PE, Senior PA, Seubert JM, Makowsky MJ, Simpson SH. Abdelmoneim AS, et al. Among authors: light pe. Diabetes Obes Metab. 2015 Jun;17(6):523-532. doi: 10.1111/dom.12456. Epub 2015 Mar 20. Diabetes Obes Metab. 2015. PMID: 25711240 Review.

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Variations in tissue selectivity amongst insulin secretagogues: a systematic review.

Abdelmoneim AS, Hasenbank SE, Seubert JM, Brocks DR, Light PE, Simpson SH. Abdelmoneim AS, et al. Among authors: light pe. Diabetes Obes Metab. 2012 Feb;14(2):130-8. doi: 10.1111/j.1463-1326.2011.01496.x. Epub 2011 Nov 3. Diabetes Obes Metab. 2012. PMID: 21923736 Review.

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Calreticulin induces dilated cardiomyopathy.

Lee D, Oka T, Hunter B, Robinson A, Papp S, Nakamura K, Srisakuldee W, Nickel BE, Light PE, Dyck JR, Lopaschuk GD, Kardami E, Opas M, Michalak M. Lee D, et al. Among authors: light pe. PLoS One. 2013;8(2):e56387. doi: 10.1371/journal.pone.0056387. Epub 2013 Feb 20. PLoS One. 2013. PMID: 23437120 Free PMC article.

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