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67 results

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Page 1
Drug-induced Brugada syndrome.
Yap YG, Behr ER, Camm AJ. Yap YG, et al. Europace. 2009 Aug;11(8):989-94. doi: 10.1093/europace/eup114. Epub 2009 May 29. Europace. 2009. PMID: 19482855 Free article. Review.
However, recently, many other pharmacological agents not related to class I anti-arrhythmic agents have been reported to induce Brugada ECG patterns including tricyclic antidepressants, fluoxetine, lithium, trifluoperazine, antihistamines, and cocaine. As published reports …
However, recently, many other pharmacological agents not related to class I anti-arrhythmic agents have been reported to induce Brugada ECG …
Lithium-induced electrocardiographic changes: A complete review.
Mehta N, Vannozzi R. Mehta N, et al. Clin Cardiol. 2017 Dec;40(12):1363-1367. doi: 10.1002/clc.22822. Epub 2017 Dec 16. Clin Cardiol. 2017. PMID: 29247520 Free PMC article. Review.
Other findings include sinus node dysfunction, sinoatrial blocks, PR prolongation, QT prolongation/dispersion, and ventricular tachyarrhythmias. Some cases have shown lithium-treated patients experiencing serious cardiac outcomes, such as ST elevation myocardial inf …
Other findings include sinus node dysfunction, sinoatrial blocks, PR prolongation, QT prolongation/dispersion, and ventricular tachya …
QT alterations in psychopharmacology: proven candidates and suspects.
Alvarez PA, Pahissa J. Alvarez PA, et al. Curr Drug Saf. 2010 Jan;5(1):97-104. doi: 10.2174/157488610789869265. Curr Drug Saf. 2010. PMID: 20210726 Review.
Psychotropics are among the most common causes of drug induced acquired long QT syndrome. Blockage of Human ether-a-go-go-related gene (HERG) potassium channel by psychoactive drugs appears to be related to this adverse effect. ...Selective serotonin reuptake inhibitors ha …
Psychotropics are among the most common causes of drug induced acquired long QT syndrome. Blockage of Human ether-a-go-go-related gen …
Consistency of psychotropic drug-drug interactions listed in drug monographs.
Liu X, Hatton RC, Zhu Y, Hincapie-Castillo JM, Bussing R, Barnicoat M, Winterstein AG. Liu X, et al. J Am Pharm Assoc (2003). 2017 Nov-Dec;57(6):698-703.e2. doi: 10.1016/j.japh.2017.07.008. Epub 2017 Aug 23. J Am Pharm Assoc (2003). 2017. PMID: 28844584 Review.
METHODS: In May 2016, we extracted severe or major psychotropic DDIs for 102 psychotropic drugs, including central nervous system (CNS) stimulants, antidepressants, an antimanic agent (lithium), antipsychotics, anticonvulsants, and anxiolytics-sedatives-hypnotics from CP, …
METHODS: In May 2016, we extracted severe or major psychotropic DDIs for 102 psychotropic drugs, including central nervous system (CNS) stim …
Treating hearts and minds: adverse cardiovascular effects of psychiatric medications.
Raja AS, Leslie SJ, Buist E, Rushworth GF, Megson IL, McNamara N. Raja AS, et al. Ther Adv Drug Saf. 2026 Mar 29;17:20420986261418947. doi: 10.1177/20420986261418947. eCollection 2026. Ther Adv Drug Saf. 2026. PMID: 41918925 Free PMC article. Review.
These adverse effects include QTc prolongation and torsades de pointes (TdP), which are phenomena associated with certain selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs) and antipsychotics. Increasing QT dispersion and induction of …
These adverse effects include QTc prolongation and torsades de pointes (TdP), which are phenomena associated with certain selective s …
Ziprasidone and the corrected QT interval: a comprehensive summary of clinical data.
Camm AJ, Karayal ON, Meltzer H, Kolluri S, O'Gorman C, Miceli J, Tensfeldt T, Kane JM. Camm AJ, et al. CNS Drugs. 2012 Apr 1;26(4):351-65. doi: 10.2165/11599010-000000000-00000. CNS Drugs. 2012. PMID: 22452529
BACKGROUND: Prolongation of the corrected QT interval (QTc) is understood to be a predictor of risk for ventricular arrhythmia; consequently, data on QTc effects of drugs are used by regulatory bodies to evaluate potential safety risks. ...Data from IM studies, and bipolar …
BACKGROUND: Prolongation of the corrected QT interval (QTc) is understood to be a predictor of risk for ventricular arrhythmia; conse …
The effectiveness of lurasidone as an adjunct to lithium or divalproex in the treatment of bipolar disorder.
Alamo C, López-Muñoz F, García-García P. Alamo C, et al. Expert Rev Neurother. 2014 Jun;14(6):593-605. doi: 10.1586/14737175.2014.915741. Epub 2014 Apr 30. Expert Rev Neurother. 2014. PMID: 24779382 Review.
Lurasidone was approved in 2010 for the treatment of schizophrenia and recently, 2013, for bipolar depression in monotherapy and an adjunct to lithium or valproate. Clinical trials have established that lurasidone adjuvant to lithium or valproate has more efficacy t …
Lurasidone was approved in 2010 for the treatment of schizophrenia and recently, 2013, for bipolar depression in monotherapy and an adjunct …
Real-world pharmacovigilance insights and clinical safety signal characterization of the classic mood stabilizer-lithium carbonate: A disproportionality analysis based on FAERS data.
Zeng Y, Wu H, Tan X, Wang R, Liu Y, Wang X, Duan J. Zeng Y, et al. J Affect Disord. 2026 Aug 1;406:121685. doi: 10.1016/j.jad.2026.121685. Epub 2026 Mar 30. J Affect Disord. 2026. PMID: 41921879
Clinicians should control dosage, monitor serum lithium/organ function (electrocardiography) and individualize assessments for high-risk groups. This study provides real-world pharmacovigilance evidence for safe lithium carbonate use....
Clinicians should control dosage, monitor serum lithium/organ function (electrocardiography) and individualize assessments for high-r …
Psychotropic drugs and the ECG: focus on the QTc interval.
Goodnick PJ, Jerry J, Parra F. Goodnick PJ, et al. Expert Opin Pharmacother. 2002 May;3(5):479-98. doi: 10.1517/14656566.3.5.479. Expert Opin Pharmacother. 2002. PMID: 11996627 Review.
The QT interval measuring depolarisation and repolarisation has, when lengthened, been implicated as a risk factor for the development of torsades de pointes and sudden death, particularly in patients predisposed to these complications due to cardiovascular impairme …
The QT interval measuring depolarisation and repolarisation has, when lengthened, been implicated as a risk factor for the developmen …
67 results