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Did you mean lcones (75 results)?
LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins.
Xu D, Marquis K, Pei J, Fu SC, Cağatay T, Grishin NV, Chook YM. Xu D, et al. Bioinformatics. 2015 May 1;31(9):1357-65. doi: 10.1093/bioinformatics/btu826. Epub 2014 Dec 15. Bioinformatics. 2015. PMID: 25515756 Free PMC article.
LocNES demonstrates both higher sensitivity and precision over existing NES prediction tools upon comparative analysis using experimentally identified NESs. AVAILABILITY AND IMPLEMENTATION: LocNES is freely available at http://prodata.swmed.edu/LocNES CONTACT …
LocNES demonstrates both higher sensitivity and precision over existing NES prediction tools upon comparative analysis using experime …
Protocol for nuclear export signal characterization of cGAS in mammalian cells.
Huang Y, McLean M, Liang C, Guo F. Huang Y, et al. STAR Protoc. 2021 Jul 3;2(3):100649. doi: 10.1016/j.xpro.2021.100649. eCollection 2021 Sep 17. STAR Protoc. 2021. PMID: 34278335 Free PMC article.
We used ISD45 or inactivated Vaccinia Virus (VACV) to stimulate cGAS and monitored cellular localization by immunofluorescence microscopy, Operetta high-content screening, and cytoplasmic/nuclear fractionation. LocNES server was used to predict cGAS nuclear export signal ( …
We used ISD45 or inactivated Vaccinia Virus (VACV) to stimulate cGAS and monitored cellular localization by immunofluorescence microscopy, O …
Mapping regions in Ste5 that support Msn5-dependent and -independent nuclear export.
Hu Z, Wang Y, Yu L, Mahanty SK, Mendoza N, Elion EA. Hu Z, et al. Biochem Cell Biol. 2016 Apr;94(2):109-28. doi: 10.1139/bcb-2015-0101. Epub 2016 Jan 29. Biochem Cell Biol. 2016. PMID: 26824509
We find no evidence for dependence on Crm1/Xpo1, despite numerous potential nuclear export sequences (NESs) detected by LocNES and NetNES1.1 predictors. Thus, Msn5 (homolog of human Exportin-5) and one or more exportins or adaptor molecules besides Crm1/Xpo1 may regulate S …
We find no evidence for dependence on Crm1/Xpo1, despite numerous potential nuclear export sequences (NESs) detected by LocNES and Ne …
Pro-515 of the dynamin-like GTPase MxB contributes to HIV-1 inhibition by regulating MxB oligomerization and binding to HIV-1 capsid.
Xu F, Zhao F, Zhao X, Zhang D, Liu X, Hu S, Mei S, Fan Z, Huang Y, Sun H, Wei L, Wu C, Li Q, Wang J, Cen S, Liang C, Guo F. Xu F, et al. J Biol Chem. 2020 May 8;295(19):6447-6456. doi: 10.1074/jbc.RA119.012439. Epub 2020 Mar 26. J Biol Chem. 2020. PMID: 32217692 Free PMC article.
Because MxB previously has been shown to reside in both the nuclear envelope and the cytoplasm, here we used bioinformatics and biochemical approaches to identify a nuclear export signal (NES) responsible for MxB's cytoplasmic location. Using the online computational tool LocN …
Because MxB previously has been shown to reside in both the nuclear envelope and the cytoplasm, here we used bioinformatics and biochemical …
NoLogo: a new statistical model highlights the diversity and suggests new classes of Crm1-dependent nuclear export signals.
Liku ME, Legere EA, Moses AM. Liku ME, et al. BMC Bioinformatics. 2018 Feb 27;19(1):65. doi: 10.1186/s12859-018-2076-7. BMC Bioinformatics. 2018. PMID: 29482494 Free PMC article.
Using this model to predict NESs, we demonstrate improved performance over PSSM and GLAM2 models, but do not achieve the performance of the state-of-the-art NES predictor LocNES. Our findings illustrate that over 30% of NESs are best described by novel NES classes rather t …
Using this model to predict NESs, we demonstrate improved performance over PSSM and GLAM2 models, but do not achieve the performance of the …