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LocTree2 predicts localization for all domains of life.
Goldberg T, Hamp T, Rost B. Goldberg T, et al. Bioinformatics. 2012 Sep 15;28(18):i458-i465. doi: 10.1093/bioinformatics/bts390. Bioinformatics. 2012. PMID: 22962467 Free PMC article.
The resulting method, LocTree2, works well even for protein fragments. It uses a hierarchical system of support vector machines that imitates the cascading mechanism of cellular sorting. The method reaches high levels of sustained performance (eukaryota: Q18=65%, bacteria: …
The resulting method, LocTree2, works well even for protein fragments. It uses a hierarchical system of support vector machines that …
LocTree3 prediction of localization.
Goldberg T, Hecht M, Hamp T, Karl T, Yachdav G, Ahmed N, Altermann U, Angerer P, Ansorge S, Balasz K, Bernhofer M, Betz A, Cizmadija L, Do KT, Gerke J, Greil R, Joerdens V, Hastreiter M, Hembach K, Herzog M, Kalemanov M, Kluge M, Meier A, Nasir H, Neumaier U, Prade V, Reeb J, Sorokoumov A, Troshani I, Vorberg S, Waldraff S, Zierer J, Nielsen H, Rost B. Goldberg T, et al. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W350-5. doi: 10.1093/nar/gku396. Epub 2014 May 21. Nucleic Acids Res. 2014. PMID: 24848019 Free PMC article.
The method outputs a score that reflects the reliability of each prediction. LocTree2 has performed on par with or better than any other state-of-the-art method. Here, we report the availability of LocTree3 as a public web server. The server includes the machine learning-b …
The method outputs a score that reflects the reliability of each prediction. LocTree2 has performed on par with or better than any ot …