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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 3
1973 11
1974 3
1975 4
1976 8
1977 8
1978 6
1979 8
1980 11
1981 6
1982 12
1983 17
1984 10
1985 16
1986 15
1987 9
1988 19
1989 21
1990 13
1991 21
1992 21
1993 26
1994 27
1995 28
1996 23
1997 22
1998 21
1999 16
2000 18
2001 19
2002 15
2003 24
2004 30
2005 19
2006 17
2007 27
2008 12
2009 16
2010 16
2011 20
2012 24
2013 23
2014 21
2015 15
2016 17
2017 13
2018 13
2019 14
2020 15
2021 16
2022 4
2023 3

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Search Results

765 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
A Comparison of Midazolam, Lorazepam, and Diazepam for the Treatment of Status Epilepticus in Children: A Network Meta-analysis.
Zhao ZY, Wang HY, Wen B, Yang ZB, Feng K, Fan JC. Zhao ZY, et al. J Child Neurol. 2016 Aug;31(9):1093-107. doi: 10.1177/0883073816638757. Epub 2016 Mar 28. J Child Neurol. 2016. PMID: 27021145 Review.
Midazolam, lorazepam, and diazepam were recommended as emergent initial therapy for status epilepticus. ...In conclusion, nonintravenous midazolam and intravenous lorazepam were superior to intravenous or nonintravenous diazepam, and intravenous lorazepam was …
Midazolam, lorazepam, and diazepam were recommended as emergent initial therapy for status epilepticus. ...In conclusion, nonintraven …
Randomized Double-blind Trial of Intramuscular Droperidol, Ziprasidone, and Lorazepam for Acute Undifferentiated Agitation in the Emergency Department.
Martel ML, Driver BE, Miner JR, Biros MH, Cole JB. Martel ML, et al. Acad Emerg Med. 2021 Apr;28(4):421-434. doi: 10.1111/acem.14124. Epub 2020 Oct 5. Acad Emerg Med. 2021. PMID: 32888340 Free article. Clinical Trial.
For the primary outcome, adequate sedation at 15 minutes, droperidol administration was effective in 16 of 25 (64%) patients, compared to seven of 28 (25%) for 10 mg of ziprasidone, 11 of 31 (35%) for 20 mg of ziprasidone, and nine of 31 (29%) for lorazepam. Pairwise compa …
For the primary outcome, adequate sedation at 15 minutes, droperidol administration was effective in 16 of 25 (64%) patients, compared to se …
Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial.
Hui D, Frisbee-Hume S, Wilson A, Dibaj SS, Nguyen T, De La Cruz M, Walker P, Zhukovsky DS, Delgado-Guay M, Vidal M, Epner D, Reddy A, Tanco K, Williams J, Hall S, Liu D, Hess K, Amin S, Breitbart W, Bruera E. Hui D, et al. JAMA. 2017 Sep 19;318(11):1047-1056. doi: 10.1001/jama.2017.11468. JAMA. 2017. PMID: 28975307 Free PMC article. Clinical Trial.
The lorazepam + haloperidol group required less median rescue neuroleptics (2.0 mg) than the placebo + haloperidol group (4.0 mg) (median difference, -1.0 mg [95% CI, -2.0 to 0]; P = .009) and was perceived to be more comfortable by both blinded caregivers and nurses (care …
The lorazepam + haloperidol group required less median rescue neuroleptics (2.0 mg) than the placebo + haloperidol group (4.0 mg) (me …
RAMPART (Rapid Anticonvulsant Medication Prior to Arrival Trial): a double-blind randomized clinical trial of the efficacy of intramuscular midazolam versus intravenous lorazepam in the prehospital treatment of status epilepticus by paramedics.
Silbergleit R, Lowenstein D, Durkalski V, Conwit R; Neurological Emergency Treatment Trials (NETT) Investigators. Silbergleit R, et al. Epilepsia. 2011 Oct;52 Suppl 8(Suppl 8):45-7. doi: 10.1111/j.1528-1167.2011.03235.x. Epilepsia. 2011. PMID: 21967361 Free PMC article. Clinical Trial.
RAMPART (Rapid Anticonvulsant Medication Prior to Arrival Trial) is a double-blind randomized clinical trial to determine if the efficacy of IM midazolam is noninferior by a margin of 10% to that of intravenous (IV) lorazepam in patients treated by paramedics for status ep …
RAMPART (Rapid Anticonvulsant Medication Prior to Arrival Trial) is a double-blind randomized clinical trial to determine if the efficacy of …
Lorazepam or diazepam for convulsive status epilepticus: A meta-analysis.
Wu W, Zhang L, Xue R. Wu W, et al. J Clin Neurosci. 2016 Jul;29:133-8. doi: 10.1016/j.jocn.2015.10.038. Epub 2016 Apr 1. J Clin Neurosci. 2016. PMID: 27052258 Review.
However, whether a particular benzodiazepine is of superior efficacy and safety in management of CSE is controversial. We performed a meta-analysis to compare the outcome of lorazepam and diazepam for treating CSE. We searched the PubMed, Medline, Embase, Cochrane Central …
However, whether a particular benzodiazepine is of superior efficacy and safety in management of CSE is controversial. We performed a meta-a …
Phenobarbital for acute alcohol withdrawal: a prospective randomized double-blind placebo-controlled study.
Rosenson J, Clements C, Simon B, Vieaux J, Graffman S, Vahidnia F, Cisse B, Lam J, Alter H. Rosenson J, et al. J Emerg Med. 2013 Mar;44(3):592-598.e2. doi: 10.1016/j.jemermed.2012.07.056. Epub 2012 Sep 19. J Emerg Med. 2013. PMID: 22999778 Clinical Trial.
All patients were placed on the institutional symptom-guided lorazepam-based alcohol withdrawal protocol. The primary outcome was initial level of hospital admission (ICU vs. telemetry vs. floor ward). ...CONCLUSIONS: A single dose of i.v. phenobarbital combined with a sym …
All patients were placed on the institutional symptom-guided lorazepam-based alcohol withdrawal protocol. The primary outcome was ini …
A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal.
Hendey GW, Dery RA, Barnes RL, Snowden B, Mentler P. Hendey GW, et al. Am J Emerg Med. 2011 May;29(4):382-5. doi: 10.1016/j.ajem.2009.10.010. Epub 2010 Mar 25. Am J Emerg Med. 2011. PMID: 20825805 Clinical Trial.
OBJECTIVE: The aim of this study was to compare phenobarbital (PB) versus lorazepam (LZ) in the treatment of alcohol withdrawal in the emergency department (ED) and at 48 hours. ...
OBJECTIVE: The aim of this study was to compare phenobarbital (PB) versus lorazepam (LZ) in the treatment of alcohol withdrawal in th …
Lorazepam as a premedication.
Gale G, Galloon S. Gale G, et al. Can Anaesth Soc J. 1976 Jan;23(1):22-9. doi: 10.1007/BF03004991. Can Anaesth Soc J. 1976. PMID: 2377 Clinical Trial.
The patients who had lorazepam required higher doses of thiopentone for the operation, and this, in part, led to longer intervals in recovery times after lorazepam. However, it is suggested that lorazepam itself was partly responsible for the longer recovery. …
The patients who had lorazepam required higher doses of thiopentone for the operation, and this, in part, led to longer intervals in …
Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children.
McTague A, Martland T, Appleton R. McTague A, et al. Cochrane Database Syst Rev. 2018 Jan 10;1(1):CD001905. doi: 10.1002/14651858.CD001905.pub3. Cochrane Database Syst Rev. 2018. PMID: 29320603 Free PMC article. Review.
Although intravenous lorazepam and intravenous diazepam lead to more rapid seizure cessation, the time taken to obtain intravenous access may undermine this effect. ...There is no evidence provided by this review to support the use of intranasal midazolam or lorazepam
Although intravenous lorazepam and intravenous diazepam lead to more rapid seizure cessation, the time taken to obtain intravenous ac …
Efficacy of ketamine for initial control of acute agitation in the emergency department: A randomized study.
Lin J, Figuerado Y, Montgomery A, Lee J, Cannis M, Norton VC, Calvo R, Sikand H. Lin J, et al. Am J Emerg Med. 2021 Jun;44:306-311. doi: 10.1016/j.ajem.2020.04.013. Epub 2020 Apr 11. Am J Emerg Med. 2021. PMID: 32340820 Clinical Trial.
Adult patients with combative agitation were randomized to ketamine (4 mg/kg IM or 1 mg/kg IV) or haloperidol/lorazepam (haloperidol 5-10 mg IM or IV + lorazepam 1-2 mg IM or IV). ...Significantly more patients who received ketamine compared to haloperidol/loraze
Adult patients with combative agitation were randomized to ketamine (4 mg/kg IM or 1 mg/kg IV) or haloperidol/lorazepam (haloperidol …
765 results