Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 6
1994 4
1995 34
1996 18
1997 25
1998 30
1999 41
2000 53
2001 52
2002 68
2003 74
2004 76
2005 51
2006 57
2007 48
2008 46
2009 56
2010 48
2011 62
2012 54
2013 60
2014 45
2015 55
2016 31
2017 27
2018 23
2019 21
2020 14
2021 21
2022 19
2023 19
2024 10
2025 12

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

1,159 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.
Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving HH, Remuzzi G, Snapinn SM, Zhang Z, Shahinfar S; RENAAL Study Investigators. Brenner BM, et al. N Engl J Med. 2001 Sep 20;345(12):861-9. doi: 10.1056/NEJMoa011161. N Engl J Med. 2001. PMID: 11565518 Free article. Clinical Trial.
The composite of morbidity and mortality from cardiovascular causes was similar in the two groups, although the rate of first hospitalization for heart failure was significantly lower with losartan (risk reduction, 32 percent; P=0.005). The level of proteinuria declined by …
The composite of morbidity and mortality from cardiovascular causes was similar in the two groups, although the rate of first hospitalizatio …
Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.
Dahlöf B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, de Faire U, Fyhrquist F, Ibsen H, Kristiansson K, Lederballe-Pedersen O, Lindholm LH, Nieminen MS, Omvik P, Oparil S, Wedel H; LIFE Study Group. Dahlöf B, et al. Lancet. 2002 Mar 23;359(9311):995-1003. doi: 10.1016/S0140-6736(02)08089-3. Lancet. 2002. PMID: 11937178 Clinical Trial.
New-onset diabetes was less frequent with losartan. Interpretation Losartan prevents more cardiovascular morbidity and death than atenolol for a similar reduction in blood pressure and is better tolerated. Losartan seems to confer benefits beyond reduction in …
New-onset diabetes was less frequent with losartan. Interpretation Losartan prevents more cardiovascular morbidity and death t …
Losartan may attenuate altitude-related sleep disturbance.
Clarke A, Ladha C, Wright A, Pattinson K; Birmingham Medical Research Expeditionary Society. Clarke A, et al. BMJ Mil Health. 2021 Dec;167(6):424-428. doi: 10.1136/jramc-2019-001308. Epub 2020 Feb 20. BMJ Mil Health. 2021. PMID: 32086272 Clinical Trial.
METHODS: Twenty participants paired by age, gender and ACE phenotype ascended to the Whymper Hut (5000 m) on Chimborazo in the Ecuadorean Andes as part of a double-blinded randomised placebo-controlled study of physiological mechanisms. Subjects were randomised to either losar …
METHODS: Twenty participants paired by age, gender and ACE phenotype ascended to the Whymper Hut (5000 m) on Chimborazo in the Ecuadorean An …
Losartan and the United States costs of end-stage renal disease by baseline albuminuria in patients with type 2 diabetes and nephropathy.
Alexander CM, Lyle PA, Keane WF, Carides GW, Zhang Z, Shahinfar S. Alexander CM, et al. Kidney Int Suppl. 2004 Nov;(92):S115-7. doi: 10.1111/j.1523-1755.2004.09228.x. Kidney Int Suppl. 2004. PMID: 15485403 Free article. Review.
The Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) study provided the opportunity to estimate costs associated with ESRD by baseline albuminuria from a United States perspective. ...The previously estimated annual ESRD-related cost sav …
The Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) study provided the opportunity to estimate c …
Enalapril versus losartan for adults with chronic kidney disease: a systematic review and meta-analysis.
He YM, Feng L, Huo DM, Yang ZH, Liao YH. He YM, et al. Nephrology (Carlton). 2013 Sep;18(9):605-14. doi: 10.1111/nep.12134. Nephrology (Carlton). 2013. PMID: 23869492
AIM: Both enalapril and losartan are effective and widely used in patients with chronic kidney disease (CKD). This review aimed to evaluate the benefits of enalapril and losartan in adults with CKD. ...CONCLUSION: Enalapril has similar effects to losartan on …
AIM: Both enalapril and losartan are effective and widely used in patients with chronic kidney disease (CKD). This review aimed to ev …
The role of losartan in the management of patients with heart failure.
Dickstein K. Dickstein K. Clin Ther. 2001 Sep;23(9):1456-77. doi: 10.1016/s0149-2918(01)80120-x. Clin Ther. 2001. PMID: 11589260 Review.
Search terms included, but were not limited to, angiotensin-converting enzyme inhibitors, angiotensin II-receptor antagonists, and losartan. RESULTS: Preclinical and clinical studies of losartan have demonstrated consistent hemodynamic effects (via selective antagon …
Search terms included, but were not limited to, angiotensin-converting enzyme inhibitors, angiotensin II-receptor antagonists, and losart …
Losartan to reduce inflammation and fibrosis endpoints in HIV disease.
Baker JV, Wolfson J, Collins G, Morse C, Rhame F, Liappis AP, Rizza S, Temesgen Z, Mystakelis H, Deeks S, Neaton J, Schacker T, Sereti I, Tracy RP. Baker JV, et al. AIDS. 2021 Mar 15;35(4):575-583. doi: 10.1097/QAD.0000000000002773. AIDS. 2021. PMID: 33252490 Free PMC article. Clinical Trial.
Changes over follow-up in (log-2 transformed) biomarkers and cell phenotypes (untransformed) were compared between losartan and placebo arms using linear mixed models. RESULTS: Among 108 PHIV (n = 52 to losartan; n = 56 to placebo), 97% had a month 12 visit. ...CD4+ …
Changes over follow-up in (log-2 transformed) biomarkers and cell phenotypes (untransformed) were compared between losartan and place …
Losartan in hospitalized patients with COVID-19 in North America: An individual participant data meta-analysis.
Di Stefano L, Ram M, Scharfstein DO, Li T, Khanal P, Baksh SN, McBee N, Bengtson CD, Gadomski A, Geriak M, Puskarich MA, Salathe MA, Schutte AE, Tignanelli CJ, Victory J, Bierer BE, Hanley DF, Freilich DA; Pandemic Response COVID-19 Research Collaboration Platform for ACEi/ARB Pooled Analyses. Di Stefano L, et al. Medicine (Baltimore). 2023 Jun 9;102(23):e33904. doi: 10.1097/MD.0000000000033904. Medicine (Baltimore). 2023. PMID: 37335665 Free PMC article.
Losartan had worse effects for those taking corticosteroids at baseline after adjusting for covariates (ratio of adjusted ORs 0.29, 95% CrI 0.08-0.99). Hypotension serious adverse event rates were numerically higher with losartan. CONCLUSIONS: In this IPD meta-analy …
Losartan had worse effects for those taking corticosteroids at baseline after adjusting for covariates (ratio of adjusted ORs 0.29, 9 …
A systematic review and meta-analysis of candesartan and losartan in the management of essential hypertension.
Zhenfeng Zheng, Huilan Shi, Junya Jia, Dong Li, Shan Lin. Zhenfeng Zheng, et al. J Renin Angiotensin Aldosterone Syst. 2011 Sep;12(3):365-74. doi: 10.1177/1470320310391503. Epub 2011 Mar 18. J Renin Angiotensin Aldosterone Syst. 2011. PMID: 21421652 Free article.
Several clinical trials have compared candesartan with losartan in the management of essential hypertension. However, systematic assessment of efficacy and safety between candesartan and losartan is still lacking. ...CONCLUSIONS: Candesartan is superior to losart …
Several clinical trials have compared candesartan with losartan in the management of essential hypertension. However, systematic asse …
1,159 results