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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 2
1987 4
1988 11
1989 11
1990 24
1991 24
1992 33
1993 37
1994 42
1995 65
1996 39
1997 60
1998 39
1999 53
2000 50
2001 66
2002 62
2003 69
2004 77
2005 85
2006 69
2007 82
2008 76
2009 90
2010 86
2011 87
2012 83
2013 87
2014 65
2015 67
2016 65
2017 64
2018 37
2019 35
2020 25
2021 31
2022 31
2023 22
2024 16
2025 14
2026 12

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1,839 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Safety and Efficacy of Topical Lovastatin Plus Cholesterol Cream vs Topical Lovastatin Cream Alone for the Treatment of Disseminated Superficial Actinic Porokeratosis: A Randomized Clinical Trial.
Santa Lucia G, Snyder A, Lateef A, Drohan A, Gregoski MJ, Barton V, Elston DM. Santa Lucia G, et al. JAMA Dermatol. 2023 May 1;159(5):488-495. doi: 10.1001/jamadermatol.2023.0205. JAMA Dermatol. 2023. PMID: 36947042 Free PMC article. Clinical Trial.
There is no effective standard of care therapy for DSAP, but treatment with topical lovastatin combined with cholesterol cream has shown promise. OBJECTIVES: To evaluate and compare the safety and efficacy of topical lovastatin 2% plus cholesterol 2% cream (lovas …
There is no effective standard of care therapy for DSAP, but treatment with topical lovastatin combined with cholesterol cream has sh …
Lovastatin in X-linked adrenoleukodystrophy.
Engelen M, Ofman R, Dijkgraaf MG, Hijzen M, van der Wardt LA, van Geel BM, de Visser M, Wanders RJ, Poll-The BT, Kemp S. Engelen M, et al. N Engl J Med. 2010 Jan 21;362(3):276-7. doi: 10.1056/NEJMc0907735. N Engl J Med. 2010. PMID: 20089986 Clinical Trial. No abstract available.
Lovastatin increases exercise-induced skeletal muscle injury.
Thompson PD, Zmuda JM, Domalik LJ, Zimet RJ, Staggers J, Guyton JR. Thompson PD, et al. Metabolism. 1997 Oct;46(10):1206-10. doi: 10.1016/s0026-0495(97)90218-3. Metabolism. 1997. PMID: 9322808 Clinical Trial.

Age, body weight, and blood lipid and lipoprotein levels were similar in lovastatin and placebo groups. Resting CK levels were 33% higher in the lovastatin group before treatment (P < .05), but were not significantly altered by lovastatin. CK levels were 6

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Age, body weight, and blood lipid and lipoprotein levels were similar in lovastatin and placebo groups. Resting CK levels were 33% hi …
Hemodynamic effects of carvedilol plus simvastatin in cirrhosis with severe portal hypertension and suboptimal response to β-blockers: A double-blind, placebo-controlled, randomized trial.
Alvarado-Tapias E, Brujats A, Puente A, Ardevol A, Rodriguez-Arias A, Fajardo J, Pavel O, Garcia-Guix M, Aracil C, Poca M, Cuyàs B, Cantó E, Montañés R, Garcia-Osuna A, Escorsell À, Torras X, Villanueva C. Alvarado-Tapias E, et al. Hepatology. 2025 Jul 1;82(1):140-154. doi: 10.1097/HEP.0000000000001148. Epub 2024 Nov 7. Hepatology. 2025. PMID: 39509369 Clinical Trial.
The interaction of diltiazem with lovastatin and pravastatin.
Azie NE, Brater DC, Becker PA, Jones DR, Hall SD. Azie NE, et al. Clin Pharmacol Ther. 1998 Oct;64(4):369-77. doi: 10.1016/S0009-9236(98)90067-4. Clin Pharmacol Ther. 1998. PMID: 9797793 Clinical Trial.
BACKGROUND: Lovastatin is oxidized by cytochrome P4503A to active metabolites but pravastatin is active alone and is not metabolized by cytochrome P450. ...Study arms were (1) administration of a single dose of 20 mg lovastatin, (2) administration of a single dose o …
BACKGROUND: Lovastatin is oxidized by cytochrome P4503A to active metabolites but pravastatin is active alone and is not metabolized …
Lovastatin for lowering cholesterol levels in non-insulin-dependent diabetes mellitus.
Garg A, Grundy SM. Garg A, et al. N Engl J Med. 1988 Jan 14;318(2):81-6. doi: 10.1056/NEJM198801143180204. N Engl J Med. 1988. PMID: 3422105 Clinical Trial.
Lovastatin (20 mg twice daily) or a placebo was given for four weeks, during which blood glucose concentrations remained controlled. ...No side effects or abnormalities in serum values were noted during short-term lovastatin therapy. The beneficial effects of lov …
Lovastatin (20 mg twice daily) or a placebo was given for four weeks, during which blood glucose concentrations remained controlled. …
Lovastatin for the adjunctive treatment of schizophrenia: a preliminary randomized double-blind placebo-controlled trial.
Ghanizadeh A, Rezaee Z, Dehbozorgi S, Berk M, Akhondzadeh S. Ghanizadeh A, et al. Psychiatry Res. 2014 Nov 30;219(3):431-5. doi: 10.1016/j.psychres.2014.06.039. Epub 2014 Jun 27. Psychiatry Res. 2014. PMID: 25017614 Clinical Trial.
However there was a significant difference between the doses of risperidone used in the two groups. The mean dose in the lovastatin and placebo groups were 4.8(1.8) and 3.4(1.4) mg/day, respectively (P<.03). No serious adverse events were reported. ...This study failed …
However there was a significant difference between the doses of risperidone used in the two groups. The mean dose in the lovastatin a …
Lovastatin and coadministered antihypertensive/cardiovascular agents.
Pool JL, Shear CL, Downton M, Schnaper H, Stinnett S, Dujovne C, Bradford RH, Chremos AN. Pool JL, et al. Hypertension. 1992 Mar;19(3):242-8. doi: 10.1161/01.hyp.19.3.242. Hypertension. 1992. PMID: 1347757 Clinical Trial.
Hypertension and hypercholesterolemia frequently coexist and may require concomitant drug treatments. The efficacy and safety profile of lovastatin given in the presence of antihypertensive medication was evaluated using patient subgroups identified in the Expanded Clinica …
Hypertension and hypercholesterolemia frequently coexist and may require concomitant drug treatments. The efficacy and safety profile of …
1,839 results