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476 results

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Page 1
Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices.
Bajema IM, Wilhelmus S, Alpers CE, Bruijn JA, Colvin RB, Cook HT, D'Agati VD, Ferrario F, Haas M, Jennette JC, Joh K, Nast CC, Noël LH, Rijnink EC, Roberts ISD, Seshan SV, Sethi S, Fogo AB. Bajema IM, et al. Kidney Int. 2018 Apr;93(4):789-796. doi: 10.1016/j.kint.2017.11.023. Epub 2018 Feb 16. Kidney Int. 2018. PMID: 29459092 Free article.
We also eliminate the class IV-S and IV-G subdivisions of class IV lupus nephritis. The active and chronic designations for class III/IV lesions are replaced by a proposal for activity and chronicity indices that should be applied to all …
We also eliminate the class IV-S and IV-G subdivisions of class IV lupus nephritis. The active and chronic desig …
Lupus Nephritis in Children: Novel Perspectives.
Pennesi M, Benvenuto S. Pennesi M, et al. Medicina (Kaunas). 2023 Oct 16;59(10):1841. doi: 10.3390/medicina59101841. Medicina (Kaunas). 2023. PMID: 37893559 Free PMC article. Review.
Kidney involvement, commonly called lupus nephritis, mainly presents with immune complex-mediated glomerulonephritis and is more frequent and severe in adults. ...This review aims to describe pediatric lupus nephritis and provide an overview of the nov …
Kidney involvement, commonly called lupus nephritis, mainly presents with immune complex-mediated glomerulonephritis and is mo …
2019 update of the EULAR recommendations for the management of systemic lupus erythematosus.
Fanouriakis A, Kostopoulou M, Alunno A, Aringer M, Bajema I, Boletis JN, Cervera R, Doria A, Gordon C, Govoni M, Houssiau F, Jayne D, Kouloumas M, Kuhn A, Larsen JL, Lerstrøm K, Moroni G, Mosca M, Schneider M, Smolen JS, Svenungsson E, Tesar V, Tincani A, Troldborg A, van Vollenhoven R, Wenzel J, Bertsias G, Boumpas DT. Fanouriakis A, et al. Ann Rheum Dis. 2019 Jun;78(6):736-745. doi: 10.1136/annrheumdis-2019-215089. Epub 2019 Mar 29. Ann Rheum Dis. 2019. PMID: 30926722 Free article.
Treatment in SLE aims at remission or low disease activity and prevention of flares. Hydroxychloroquine is recommended in all patients with lupus, at a dose not exceeding 5 mg/kg real body weight. During chronic maintenance treatment, glucocorticoids (GC) sho …
Treatment in SLE aims at remission or low disease activity and prevention of flares. Hydroxychloroquine is recommended in all patient …
The BAFF/APRIL system: emerging functions beyond B cell biology and autoimmunity.
Vincent FB, Saulep-Easton D, Figgett WA, Fairfax KA, Mackay F. Vincent FB, et al. Cytokine Growth Factor Rev. 2013 Jun;24(3):203-15. doi: 10.1016/j.cytogfr.2013.04.003. Epub 2013 May 15. Cytokine Growth Factor Rev. 2013. PMID: 23684423 Free PMC article. Review.
The BAFF system plays a key role in the development of autoimmunity, especially in systemic lupus erythematosus (SLE). This often leads to the assumption that BAFF is mostly a B cell factor with a specific role in autoimmunity. ...
The BAFF system plays a key role in the development of autoimmunity, especially in systemic lupus erythematosus (SLE). This often lea …
Beyond ISN/RPS Lupus Nephritis Classification: Adding Chronicity Index to Clinical Variables Predicts Kidney Survival.
Moroni G, Porata G, Raffiotta F, Quaglini S, Frontini G, Sacchi L, Binda V, Calatroni M, Reggiani F, Banfi G, Ponticelli C. Moroni G, et al. Kidney360. 2021 Nov 5;3(1):122-132. doi: 10.34067/KID.0005512021. eCollection 2022 Jan 27. Kidney360. 2021. PMID: 35368572 Free PMC article.
BACKGROUND: A renewed interest for activity and chronicity indices as predictors of lupus nephritis (LN) outcome has emerged. ...The chronicity index was correlated with serum creatinine. Thus, serum creatinine was significantly and direc …
BACKGROUND: A renewed interest for activity and chronicity indices as predictors of lupus nephritis (LN) outcome …
Efficacy and safety of immunosuppressive agents for adults with lupus nephritis: a systematic review and network meta-analysis.
Jiang N, Jin S, Yu C, Zhao J, Wang Q, Tian X, Li M, Zeng X. Jiang N, et al. Front Immunol. 2023 Oct 13;14:1232244. doi: 10.3389/fimmu.2023.1232244. eCollection 2023. Front Immunol. 2023. PMID: 37901212 Free PMC article.
INTRODUCTION: Various immunosuppressive regimens have been developed for the treatment of lupus nephritis (LN). This study aimed to compare the efficacy and safety of immunosuppressive regimens in adults with LN. ...The secondary endpoints were complete remission, s …
INTRODUCTION: Various immunosuppressive regimens have been developed for the treatment of lupus nephritis (LN). This study aim …
Circulating plasma derived exosomes from systemic lupus erythematosus aggravate lupus nephritis through miR-122-5p/FOXO3-mediated macrophage activation.
Ji J, He Q, Xia Y, Sha X, Liang Q, Xu Y, Chen P, Dong C, Zhao R, Yang J, Guo H, Wang Y, Cao H, Li J, Yang M, Gu Z. Ji J, et al. J Nanobiotechnology. 2024 Dec 19;22(1):779. doi: 10.1186/s12951-024-03063-6. J Nanobiotechnology. 2024. PMID: 39702207 Free PMC article.
Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease characterized by dysregulation in both innate and adaptive immunity. ...Of them, the expression of miR-122-5p was significantly upregulated in SLE exosomes, and positively correlated wit …
Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease characterized by dysregulation in both innate …
Glomerular Exostosin-Positivity is Associated With Disease Activity and Outcomes in Patients With Membranous Lupus Nephritis.
Xia X, Li S, Wang Z, Ye S, Fan Y, Peng W, Chen W, Huang F, Tang R, Chen W. Xia X, et al. Kidney Int Rep. 2024 Jan 10;9(4):1040-1046. doi: 10.1016/j.ekir.2024.01.008. eCollection 2024 Apr. Kidney Int Rep. 2024. PMID: 38765564 Free PMC article.
INTRODUCTION: The relationship of exostosin 1 and exostosin 2 (EXT1/EXT2) expression and outcomes in membranous lupus nephritis (MLN) was controversial. METHODS: EXT1/EXT2 was performed by immunohistochemistry (IHC) in 283 consecutive patients with MLN. ...For EXT1/ …
INTRODUCTION: The relationship of exostosin 1 and exostosin 2 (EXT1/EXT2) expression and outcomes in membranous lupus nephritis …
Sex differences in mortality among patients with lupus nephritis.
Xiang W, Xia X, Lu Y, Zhang X, Shi X, Jia X, Tang R, Chen W. Xiang W, et al. Eur J Med Res. 2024 Oct 18;29(1):500. doi: 10.1186/s40001-024-02089-8. Eur J Med Res. 2024. PMID: 39420384 Free PMC article.
OBJECTIVE: To evaluate the prognostic importance of sex in lupus nephritis (LN). METHODS: A retrospective cohort of 1048 biopsy-confirmed LN patients, diagnosed between January 1, 1996, and December 31, 2018, was analyzed. ...Cox regression analysis highlighted male …
OBJECTIVE: To evaluate the prognostic importance of sex in lupus nephritis (LN). METHODS: A retrospective cohort of 1048 biops …
Predictors of increase in chronicity index and of kidney function impairment at repeat biopsy in lupus nephritis.
Moroni G, Porata G, Raffiotta F, Frontini G, Calatroni M, Reggiani F, Banfi G, Ponticelli C. Moroni G, et al. Lupus Sci Med. 2022 Aug;9(1):e000721. doi: 10.1136/lupus-2022-000721. Lupus Sci Med. 2022. PMID: 35973744 Free PMC article.
OBJECTIVES: Based on available data, the histological predictors of long-term outcome of lupus nephritis (LN) are not clearly defined. Aims of this retrospective study were: (i) to evaluate the change of chronicity index from the first to second kidney …
OBJECTIVES: Based on available data, the histological predictors of long-term outcome of lupus nephritis (LN) are not clearly …
476 results