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169 results

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Page 1
Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis.
Duan H, Zhang Q, Liu J, Li R, Wang D, Peng W, Wu C. Duan H, et al. Pharmacol Res. 2021 Jun;168:105599. doi: 10.1016/j.phrs.2021.105599. Epub 2021 Apr 7. Pharmacol Res. 2021. PMID: 33838291 Review.
Therefore, this paper reviewed current studies on the inhibitory effect of natural medicines on endothelial cell apoptosis and summarized the risk factors that may induce endothelial cell apoptosis, including oxidized low-density lipoprotein (ox-LDL …
Therefore, this paper reviewed current studies on the inhibitory effect of natural medicines on endothelial cell apoptosis and summarized th …
Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic.
Fuhrman B, Volkova N, Rosenblat M, Aviram M. Fuhrman B, et al. Antioxid Redox Signal. 2000 Fall;2(3):491-506. doi: 10.1089/15230860050192279. Antioxid Redox Signal. 2000. PMID: 11229363
Several lines of evidence suggest that oxidatively modified low-density lipoprotein (LDL) is atherogenic, and that atherosclerosis can be attenuated by natural antioxidants, which inhibit LDL oxidation. This study was conducted to determine the effect …
Several lines of evidence suggest that oxidatively modified low-density lipoprotein (LDL) is atherogenic, and that atheroscler …
Tomato lycopene and low density lipoprotein oxidation: a human dietary intervention study.
Agarwal S, Rao AV. Agarwal S, et al. Lipids. 1998 Oct;33(10):981-4. doi: 10.1007/s11745-998-0295-6. Lipids. 1998. PMID: 9832077 Clinical Trial.
A study was undertaken to investigate the effect of dietary supplementation of lycopene on LDL oxidation in 19 healthy human subjects. Dietary lycopene was provided using tomato juice, spaghetti sauce, and tomato oleoresin for a period of 1 wk each. .. …
A study was undertaken to investigate the effect of dietary supplementation of lycopene on LDL oxidation in 19 healthy …
Combined Effects of Curcumin and Lycopene or Bixin in Yoghurt on Inhibition of LDL Oxidation and Increases in HDL and Paraoxonase Levels in Streptozotocin-Diabetic Rats.
Assis RP, Arcaro CA, Gutierres VO, Oliveira JO, Costa PI, Baviera AM, Brunetti IL. Assis RP, et al. Int J Mol Sci. 2017 Mar 23;18(4):332. doi: 10.3390/ijms18040332. Int J Mol Sci. 2017. PMID: 28333071 Free PMC article.
Treatment of STZ-diabetic rats with natural products individually decreased glycemia, triacylglycerol, total-cholesterol, oxidative stress biomarkers, including oxidized low-density lipoprotein (ox-LDL), and increased the activities of an …
Treatment of STZ-diabetic rats with natural products individually decreased glycemia, triacylglycerol, total-cholesterol, oxidative s …
Impact of LDL carotenoid and alpha-tocopherol content on LDL oxidation by endothelial cells in culture.
Dugas TR, Morel DW, Harrison EH. Dugas TR, et al. J Lipid Res. 1998 May;39(5):999-1007. J Lipid Res. 1998. PMID: 9610766 Free article.
Additionally, in vitro enrichment of LDL with beta-carotene, but not with lutein or lycopene, inhibited LDL oxidation. In the present studies the impact of LDL carotenoid and alpha-tocopherol content on LDL oxidation by human endot …
Additionally, in vitro enrichment of LDL with beta-carotene, but not with lutein or lycopene, inhibited LDL oxidatio …
Effect of thyroid function on LDL oxidation.
Costantini F, Pierdomenico SD, De Cesare D, De Remigis P, Bucciarelli T, Bittolo-Bon G, Cazzolato G, Nubile G, Guagnano MT, Sensi S, Cuccurullo F, Mezzetti A. Costantini F, et al. Arterioscler Thromb Vasc Biol. 1998 May;18(5):732-7. doi: 10.1161/01.atv.18.5.732. Arterioscler Thromb Vasc Biol. 1998. PMID: 9598831
In fact, in hypothyroidism, LDL oxidation was significantly lower than in hyperthyroidism but higher than in the control group. ...On the contrary, in hypothyroidism LDL oxidation was strongly and significantly related to serum lipids. In conclusion, b …
In fact, in hypothyroidism, LDL oxidation was significantly lower than in hyperthyroidism but higher than in the control group …
Does lycopene offer human LDL any protection against myeloperoxidase activity?
Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. Chew PY, et al. Mol Cell Biochem. 2012 Feb;361(1-2):181-7. doi: 10.1007/s11010-011-1102-0. Epub 2011 Oct 11. Mol Cell Biochem. 2012. PMID: 21987235
One of the early events in the aetiology of atherosclerosis is thought to be the oxidation of LDL. Myeloperoxidase an enzyme secreted by neutrophils and macrophages is thought to oxidise human LDL particles. In this study, isolated human LDL was …
One of the early events in the aetiology of atherosclerosis is thought to be the oxidation of LDL. Myeloperoxidase an enzyme s …
LDL oxidation by arterial wall macrophages depends on the oxidative status in the lipoprotein and in the cells: role of prooxidants vs. antioxidants.
Aviram M, Fuhrman B. Aviram M, et al. Mol Cell Biochem. 1998 Nov;188(1-2):149-59. Mol Cell Biochem. 1998. PMID: 9823020 Review.
All major cells in the arterial wall including endothelial cells, smooth muscle cells and monocyte derived macrophages can oxidize LDL. Macrophage-mediated oxidation of LDL is probably a hallmark in early atherosclerosis, and it depends on the oxida …
All major cells in the arterial wall including endothelial cells, smooth muscle cells and monocyte derived macrophages can oxidize …
Tomato juice decreases LDL cholesterol levels and increases LDL resistance to oxidation.
Silaste ML, Alfthan G, Aro A, Kesäniemi YA, Hörkkö S. Silaste ML, et al. Br J Nutr. 2007 Dec;98(6):1251-8. doi: 10.1017/S0007114507787445. Epub 2007 Jul 9. Br J Nutr. 2007. PMID: 17617941 Clinical Trial.
The level of circulating LDL to resist formation of oxidized phospholipids increased 13 % (P = 0.02) in response to the high tomato diet. In conclusion, a high dietary intake of tomato products had atheroprotective effects, it significantly reduced LDL choles …
The level of circulating LDL to resist formation of oxidized phospholipids increased 13 % (P = 0.02) in response to the high t …
The antioxidative effects of the isoflavan glabridin on endogenous constituents of LDL during its oxidation.
Belinky PA, Aviram M, Fuhrman B, Rosenblat M, Vaya J. Belinky PA, et al. Atherosclerosis. 1998 Mar;137(1):49-61. doi: 10.1016/s0021-9150(97)00251-7. Atherosclerosis. 1998. PMID: 9568736
Glabridin also inhibited the consumption of beta-carotene and lycopene by 38 and 52%, respectively, after 0.5 h of LDL oxidation with AAPH, but failed to protect vitamin E. The in vivo and in vitro reduction of the susceptibility of LDL to oxidation …
Glabridin also inhibited the consumption of beta-carotene and lycopene by 38 and 52%, respectively, after 0.5 h of LDL oxid …
169 results