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Branched-chain amino acids in metabolic signalling and insulin resistance.
Lynch CJ, Adams SH. Lynch CJ, et al. Nat Rev Endocrinol. 2014 Dec;10(12):723-36. doi: 10.1038/nrendo.2014.171. Epub 2014 Oct 7. Nat Rev Endocrinol. 2014. PMID: 25287287 Free PMC article. Review.
Branched-chain amino acids (BCAAs) are important nutrient signals that have direct and indirect effects. ...However, circulating levels of BCAAs tend to be increased in individuals with obesity and are associated with worse metabolic heal …
Branched-chain amino acids (BCAAs) are important nutrient signals that have direct and indirect effects. …
Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity.
Lackey DE, Lynch CJ, Olson KC, Mostaedi R, Ali M, Smith WH, Karpe F, Humphreys S, Bedinger DH, Dunn TN, Thomas AP, Oort PJ, Kieffer DA, Amin R, Bettaieb A, Haj FG, Permana P, Anthony TG, Adams SH. Lackey DE, et al. Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1175-87. doi: 10.1152/ajpendo.00630.2012. Epub 2013 Mar 19. Am J Physiol Endocrinol Metab. 2013. PMID: 23512805 Free PMC article.
Elevated blood branched-chain amino acids (BCAA) are often associated with insulin resistance and type 2 diabetes, which might result from a reduced cellular utilization and/or incomplete BCAA oxidation. ...The results support the hypothe …
Elevated blood branched-chain amino acids (BCAA) are often associated with insulin resistance and …