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1964 1
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1985 2
1998 2
1999 1
2000 1
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2003 4
2004 5
2005 3
2006 1
2007 2
2008 1
2009 2
2010 3
2011 1
2012 3
2013 2
2014 4
2015 7
2016 1
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2019 1
2021 2
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Lignans from Machilus thunbergii as Thymic Stromal Lymphopoietin Inhibitors.
Shin H, Han YK, Byun Y, Jeon YH, Lee KY. Shin H, et al. Molecules. 2021 Aug 8;26(16):4804. doi: 10.3390/molecules26164804. Molecules. 2021. PMID: 34443392 Free PMC article.
The primary focus of this study was the identification of potent inhibitors of the TSLP signaling pathway for potential therapeutic use. The 80% methanol extract of Machilus thunbergii bark significantly inhibited the signal transducer and activator of transcription …
The primary focus of this study was the identification of potent inhibitors of the TSLP signaling pathway for potential therapeutic use. The …
Effects of Machilus thunbergii Sieb et Zucc on UV-induced photoaging in hairless mice.
Uhm YK, Jung KH, Bu HJ, Jung MY, Lee MH, Lee S, Lee S, Kim HK, Yim SV. Uhm YK, et al. Phytother Res. 2010 Sep;24(9):1339-46. doi: 10.1002/ptr.3117. Phytother Res. 2010. PMID: 20127882
Chronic ultraviolet (UV) exposure induces photoaging and oxidative stress in the skin. We investigated whether Machilus thunbergii Sieb et Zucc (M. thunbergii) could reduce UV-induced photoaging and oxidative stress in hairless mice. ...The thickness of the d …
Chronic ultraviolet (UV) exposure induces photoaging and oxidative stress in the skin. We investigated whether Machilus thunbergii …
Obtusilactone B from Machilus Thunbergii targets barrier-to-autointegration factor to treat cancer.
Kim W, Lyu HN, Kwon HS, Kim YS, Lee KH, Kim DY, Chakraborty G, Choi KY, Yoon HS, Kim KT. Kim W, et al. Mol Pharmacol. 2013 Feb;83(2):367-76. doi: 10.1124/mol.112.082578. Epub 2012 Nov 13. Mol Pharmacol. 2013. PMID: 23150487
However, the continued development of novel molecular targeting inhibitors is required to target the various oncogenes associated with the diverse types and stages of cancer. Obtusilactone B is a butanolide derivative purified from Machilus thunbergii. In this study …
However, the continued development of novel molecular targeting inhibitors is required to target the various oncogenes associated with the d …
New neuroprotective dibenzylbutane lignans isolated from Machilus thunbergii.
Ma CJ, Sung SH, Kim YC. Ma CJ, et al. Nat Prod Res. 2010 Apr;24(6):562-8. doi: 10.1080/14786410902823279. Nat Prod Res. 2010. PMID: 20397106
Two new dibenzylbutane lignans, namely rel-methyl (2S)-2-hydroxy-2-2'-((2''R,3''R)-4''-guaiacyl-2'',3''dimethylbutyl)-5'-oxo-2',5'-dihydro-2-furanylethnoate (1) and rel-methyl (2S)-2-hydroxy-2-2'-((2''R,3''S)-4''-guaiacyl-2'',3''dimethylbutyl)-5'-oxo-2',5'-dihydro-2-furanylethnoa …
Two new dibenzylbutane lignans, namely rel-methyl (2S)-2-hydroxy-2-2'-((2''R,3''R)-4''-guaiacyl-2'',3''dimethylbutyl)-5'-oxo-2',5'-dihydro-2 …
Neuroprotective lignans from the bark of Machilus thunbergii.
Ma CJ, Sung SH, Kim YC. Ma CJ, et al. Planta Med. 2004 Jan;70(1):79-80. doi: 10.1055/s-2004-815463. Planta Med. 2004. PMID: 14765301
The CH (2)Cl (2) fraction of the bark of Machilus thunbergii Sieb. et Zucc. (Lauraceae) significantly protected primary cultures of rat cortical cells exposed to the excitotoxic amino acid, L-glutamate. (-)-Isoguaiacin, meso-dihydroguaiaretic acid, machilin A, (+)-g …
The CH (2)Cl (2) fraction of the bark of Machilus thunbergii Sieb. et Zucc. (Lauraceae) significantly protected primary cultur …
Meso-dihydroguaiaretic acid from Machilus thunbergii SIEB et ZUCC., and its effects on the expression of matrix metalloproteinase-2, 9 cause by ultraviolet irradiated cultured human keratinocyte cells (HaCaT).
Moon HI, Chung JH. Moon HI, et al. Biol Pharm Bull. 2005 Nov;28(11):2176-9. doi: 10.1248/bpb.28.2176. Biol Pharm Bull. 2005. PMID: 16272716 Free article.
Ethanol and aqueous extracts of Machilus thunbergii used traditionally for the treatments a wide variety of diseases were screened in vitro for the matrix metalloproteinase (MMP)-9 inhibitor actions. Meso-dihydroguaiaretic acid from the stems bark of Machilus …
Ethanol and aqueous extracts of Machilus thunbergii used traditionally for the treatments a wide variety of diseases were scre …
Stimulatory activity of lignans from Machilus thunbergii on osteoblast differentiation.
Lee MK, Yang H, Ma CJ, Kim YC. Lee MK, et al. Biol Pharm Bull. 2007 Apr;30(4):814-7. doi: 10.1248/bpb.30.814. Biol Pharm Bull. 2007. PMID: 17409528 Free article.
In the present study, we evaluated the stimulating activity of six lignans, meso-dihydroguaiaretic acid, nordihydroguaiaretic acid, machilin A, guaiacin, isoguaiacin and isoguaiacin dimethylether, from Machilus thunbergii, on osteoblast differentiation employing pri …
In the present study, we evaluated the stimulating activity of six lignans, meso-dihydroguaiaretic acid, nordihydroguaiaretic acid, machilin …
Butanolides from Machilus thunbergii and their inhibitory activity on nitric oxide synthesis in activated macrophages.
Kim NY, Ryu JH. Kim NY, et al. Phytother Res. 2003 Apr;17(4):372-5. doi: 10.1002/ptr.1160. Phytother Res. 2003. PMID: 12722143
In activated macrophages the inducible form of nitric oxide synthase (iNOS) generates high amounts of the toxic mediator, nitric oxide (NO), that contributes to the circulatory failure associated with septic shock. Three butanolides were isolated from Machilus thunbergi …
In activated macrophages the inducible form of nitric oxide synthase (iNOS) generates high amounts of the toxic mediator, nitric oxide (NO), …
Compounds with neuroprotective activity from the medicinal plant Machilus thunbergii.
Ma CJ, Kim YC, Sung SH. Ma CJ, et al. J Enzyme Inhib Med Chem. 2009 Oct;24(5):1117-21. doi: 10.1080/14756360802632971. J Enzyme Inhib Med Chem. 2009. PMID: 19555186
The dichloromethane fraction of the bark of Machilus thunbergii Sieb. et Zucc. (Lauraceae) significantly protected primary cultures of rat cortical cells exposed to the excitotoxic amino acid, L-glutamate. ...
The dichloromethane fraction of the bark of Machilus thunbergii Sieb. et Zucc. (Lauraceae) significantly protected primary cul …
50 results