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Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial.
Sanmukhani J, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB. Sanmukhani J, et al. Phytother Res. 2014 Apr;28(4):579-85. doi: 10.1002/ptr.5025. Epub 2013 Jul 6. Phytother Res. 2014. PMID: 23832433 Clinical Trial.
The objectives of this trial were to compare the efficacy and safety of curcumin with fluoxetine in patients with major depressive disorder (MDD). Herein, 60 patients diagnosed with MDD were randomized in a 1:1:1 ratio for six weeks observer-mas …
The objectives of this trial were to compare the efficacy and safety of curcumin with fluoxetine in patients with major
Evaluation of Nanocurcumin Effects on Depressive-Like Behaviors in Rats and Determination of Serum BDNF and Serotonin Levels.
Jahromi MH, Charousaei H, Charousaei A. Jahromi MH, et al. Brain Behav. 2025 Feb;15(2):e70320. doi: 10.1002/brb3.70320. Brain Behav. 2025. PMID: 39972664 Free PMC article.
INTRODUCTION: Major depressive disorder (MDD) is a highly prevalent psychiatric condition worldwide, and it is the leading cause of disability globally. ...However, curcumin's low bioavailability limits its effectiveness. This study evaluated na …
INTRODUCTION: Major depressive disorder (MDD) is a highly prevalent psychiatric condition worldwide, and it is the lead …