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1

Modified DNA Aptamers for C-Reactive Protein and Lactate Dehydrogenase-5 with Sub-Nanomolar Affinities.

Minagawa H, Kataoka Y, Fujita H, Kuwahara M, Horii K, Shiratori I, Waga I. Minagawa H, et al. Among authors: Kuwahara M. Int J Mol Sci. 2020 Apr 13;21(8):2683. doi: 10.3390/ijms21082683. Int J Mol Sci. 2020. PMID: 32294882 Free PMC article.

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2

A high affinity modified DNA aptamer containing base-appended bases for human β-defensin.

Minagawa H, Kataoka Y, Kuwahara M, Horii K, Shiratori I, Waga I. Minagawa H, et al. Among authors: Kuwahara M. Anal Biochem. 2020 Apr 1;594:113627. doi: 10.1016/j.ab.2020.113627. Epub 2020 Feb 15. Anal Biochem. 2020. PMID: 32067984

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3

Fluorescence Polarization-Based Rapid Detection System for Salivary Biomarkers Using Modified DNA Aptamers Containing Base-Appended Bases.

Minagawa H, Shimizu A, Kataoka Y, Kuwahara M, Kato S, Horii K, Shiratori I, Waga I. Minagawa H, et al. Among authors: Kuwahara M. Anal Chem. 2020 Jan 21;92(2):1780-1787. doi: 10.1021/acs.analchem.9b03450. Epub 2020 Jan 2. Anal Chem. 2020. PMID: 31855403

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4

In situ condensation of an anti-cancer drug into fibrin gel enabling effective inhibition of tumor cell growth.

Kuwahara M, Fujita H, Kataoka Y, Nakajima Y, Yamada M, Sugimoto N. Kuwahara M, et al. Chem Commun (Camb). 2019 Oct 7;55(78):11679-11682. doi: 10.1039/c9cc06418d. Epub 2019 Sep 16. Chem Commun (Camb). 2019. PMID: 31524892

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5

Seconds-resolved pharmacokinetic measurements of the chemotherapeutic irinotecan in situ in the living body.

Idili A, Arroyo-Currás N, Ploense KL, Csordas AT, Kuwahara M, Kippin TE, Plaxco KW. Idili A, et al. Among authors: Kuwahara M. Chem Sci. 2019 Jul 22;10(35):8164-8170. doi: 10.1039/c9sc01495k. eCollection 2019 Sep 21. Chem Sci. 2019. PMID: 31673321 Free PMC article.

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6

High-Contrast Facile Imaging with Target-Directing Fluorescent Molecular Rotors, the N³-Modified Thioflavin T Derivatives.

Kataoka Y, Fujita H, Afanaseva A, Nagao C, Mizuguchi K, Kasahara Y, Obika S, Kuwahara M. Kataoka Y, et al. Among authors: Kuwahara M. Biochemistry. 2019 Feb 12;58(6):493-498. doi: 10.1021/acs.biochem.8b01181. Epub 2019 Jan 7. Biochemistry. 2019. PMID: 30595015

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7

Correction: Development of oligonucleotide-based antagonists of Ebola virus protein 24 inhibiting its interaction with karyopherin alpha 1.

Tanaka K, Kasahara Y, Miyamoto Y, Okuda T, Kasai T, Onodera K, Kuwahara M, Oka M, Yoneda Y, Obika S. Tanaka K, et al. Among authors: Kuwahara M. Org Biomol Chem. 2018 Oct 17;16(40):7530. doi: 10.1039/c8ob90140f. Org Biomol Chem. 2018. PMID: 30283945

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8

Development of oligonucleotide-based antagonists of Ebola virus protein 24 inhibiting its interaction with karyopherin alpha 1.

Tanaka K, Kasahara Y, Miyamoto Y, Okuda T, Kasai T, Onodera K, Kuwahara M, Oka M, Yoneda Y, Obika S. Tanaka K, et al. Among authors: Kuwahara M. Org Biomol Chem. 2018 Jun 20;16(24):4456-4463. doi: 10.1039/c8ob00706c. Org Biomol Chem. 2018. PMID: 29850750

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9

Selective incorporation of foreign functionality into fibrin gels through a chemically modified DNA aptamer.

Fujita H, Inoue Y, Kuwahara M. Fujita H, et al. Among authors: Kuwahara M. Bioorg Med Chem Lett. 2018 Jan 1;28(1):35-39. doi: 10.1016/j.bmcl.2017.11.022. Epub 2017 Nov 11. Bioorg Med Chem Lett. 2018. PMID: 29162456

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10

Specific Light-Up System for Protein and Metabolite Targets Triggered by Initiation Complex Formation.

Fujita H, Kataoka Y, Nagano R, Nakajima Y, Yamada M, Sugimoto N, Kuwahara M. Fujita H, et al. Among authors: Kuwahara M. Sci Rep. 2017 Nov 9;7(1):15191. doi: 10.1038/s41598-017-15697-8. Sci Rep. 2017. PMID: 29123195 Free PMC article.

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