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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1991 3
1992 2
1993 4
1994 1
1995 3
1996 4
1997 8
1998 4
1999 5
2000 6
2001 3
2002 7
2003 5
2004 10
2005 6
2006 10
2007 11
2008 11
2009 10
2010 7
2011 9
2012 5
2013 9
2014 7
2015 6
2016 13
2017 18
2018 8
2019 11
2020 14
2021 6
2022 9
2023 11
2024 13
2025 12
2026 10

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260 results

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Page 1
UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.
Yeo MJR, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Nguyen K, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Carr SA, Udeshi ND, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N. Yeo MJR, et al. Among authors: mattevi a. Nature. 2025 Mar;639(8053):232-240. doi: 10.1038/s41586-024-08532-4. Epub 2025 Feb 12. Nature. 2025. PMID: 39939761 Free PMC article.
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1.
Lee K, Barone M, Waterbury AL, Jiang H, Nam E, DuBois-Coyne SE, Whedon SD, Wang ZA, Caroli J, Neal K, Ibeabuchi B, Dhoondia Z, Kuroda MI, Liau BB, Beck S, Mattevi A, Cole PA. Lee K, et al. Among authors: mattevi a. Nat Chem Biol. 2025 Feb;21(2):227-237. doi: 10.1038/s41589-024-01671-9. Epub 2024 Jul 4. Nat Chem Biol. 2025. PMID: 38965385 Free PMC article.
A synergistic interaction between PRMT5 and LSD1 inhibitors in AML.
Param NJ, Arceci E, Fiorentino F, Pignata L, Torre D, Gutiérrez-Trejo N, Fong JY, Goy PA, Han BY, Lambona C, Di Bello E, Castiello C, Barone M, Schwarz M, Arrowsmith C, Ito K, Scherle P, Wee DKB, Ndoye S, Tabaglio T, Jeyasekharan AD, Lakshmanan M, Cirilli R, Habisch H, Madl T, Mattevi A, Valente S, Mai A, Guccione E. Param NJ, et al. Among authors: mattevi a. Sci Adv. 2026 Mar 27;12(13):eaea4059. doi: 10.1126/sciadv.aea4059. Epub 2026 Mar 27. Sci Adv. 2026. PMID: 41894488 Free PMC article.
The scaffolding function of LSD1 controls DNA methylation in mouse ESCs.
Malla S, Kumari K, García-Prieto CA, Caroli J, Nordin A, Phan TTT, Bhattarai DP, Martinez-Gamero C, Dorafshan E, Stransky S, Álvarez-Errico D, Saiki PA, Lai W, Lyu C, Lizana L, Gilthorpe JD, Wang H, Sidoli S, Mateus A, Lee DF, Cantù C, Esteller M, Mattevi A, Roman AC, Aguilo F. Malla S, et al. Among authors: mattevi a. Nat Commun. 2024 Sep 5;15(1):7758. doi: 10.1038/s41467-024-51966-7. Nat Commun. 2024. PMID: 39237615 Free PMC article.
The VAO/PCMH flavoprotein family.
Ewing TA, Fraaije MW, Mattevi A, van Berkel WJH. Ewing TA, et al. Among authors: mattevi a. Arch Biochem Biophys. 2017 Oct 15;632:104-117. doi: 10.1016/j.abb.2017.06.022. Epub 2017 Jun 30. Arch Biochem Biophys. 2017. PMID: 28669855 Review.
The NPAC-LSD2 complex in nucleosome demethylation.
Caroli J, Mattevi A. Caroli J, et al. Among authors: mattevi a. Enzymes. 2023;53:97-111. doi: 10.1016/bs.enz.2023.03.003. Epub 2023 Apr 21. Enzymes. 2023. PMID: 37748839 Review.
Structural Elucidation and Engineering of a Bacterial Carbohydrate Oxidase.
Boverio A, Widodo WS, Santema LL, Rozeboom HJ, Xiang R, Guallar V, Mattevi A, Fraaije MW. Boverio A, et al. Among authors: mattevi a. Biochemistry. 2023 Jan 17;62(2):429-436. doi: 10.1021/acs.biochem.2c00307. Epub 2022 Jul 26. Biochemistry. 2023. PMID: 35881507 Free PMC article.
LSD1 inhibition suppresses ASCL1 and de-represses YAP1 to drive potent activity against neuroendocrine prostate cancer.
Mandl A, Jasmine S, Krueger T, Kumar R, Coleman IM, Dalrymple SL, Antony L, Rosen DM, Jing Y, Hanratty B, Patel RA, Jin-Yih L, Dias J, Celatka CA, Tapper AE, Kleppe M, Kanayama M, Speranzini V, Wang YZ, Luo J, Corey E, Sena LA, Casero RA, Lotan T, Trock BJ, Kachhap SK, Denmeade SR, Carducci MA, Mattevi A, Haffner MC, Nelson PS, Rienhoff HY, Isaacs JT, Brennen WN. Mandl A, et al. Among authors: mattevi a. bioRxiv [Preprint]. 2024 Jan 22:2024.01.17.576106. doi: 10.1101/2024.01.17.576106. bioRxiv. 2024. PMID: 38328141 Free PMC article. Preprint.
260 results