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2016 10
2017 60
2018 13
2021 0
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Page 1
Sex-specific transcriptional signatures in human depression.
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, Kronman H, Pfau M, Obradovic ALJ, Dong Y, Neve RL, Russo S, Kazarskis A, Tamminga C, Mechawar N, Turecki G, Zhang B, Shen L, Nestler EJ. Labonté B, et al. Nat Med. 2017 Sep;23(9):1102-1111. doi: 10.1038/nm.4386. Epub 2017 Aug 21. Nat Med. 2017. PMID: 28825715 Free PMC article.
Neuropathology of suicide: recent findings and future directions.
Lutz PE, Mechawar N, Turecki G. Lutz PE, et al. Mol Psychiatry. 2017 Oct;22(10):1395-1412. doi: 10.1038/mp.2017.141. Epub 2017 Jul 11. Mol Psychiatry. 2017. PMID: 28696430 Review.
Suicide is a major public health concern and a leading cause of death in most societies. ...More recently, the unravelling of the unique epigenetic processes that occur in the brain has opened promising avenues in suicide research. The present review explores the va …
Suicide is a major public health concern and a leading cause of death in most societies. ...More recently, the unravelling of the uni …
[Wernicke encephalopathy: Guiding thiamine prescription].
Boulanger AS, Paquette I, Létourneau G, Richard-Devantoy S. Boulanger AS, et al. Encephale. 2017 May;43(3):259-267. doi: 10.1016/j.encep.2016.04.011. Epub 2016 Sep 9. Encephale. 2017. PMID: 27623120 Review. French.
METHODS: A systematic literature search was performed using Medline to include all studies published between January 1, 2000 and December 31, 2015. RESULTS: Of the 316 abstracts identified, 20 met the final inclusion criteria. ...
METHODS: A systematic literature search was performed using Medline to include all studies published between January 1, 2000 and Dece …
MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.
Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, Farzan F, Leri F, MacQueen GM, Feilotter H, Tyryshkin K, Evans KR, Giacobbe P, Blier P, Lam RW, Milev R, Parikh SV, Rotzinger S, Strother SC, Lewis CM, Aitchison KJ, Wittenberg GM, Mechawar N, Nestler EJ, Uher R, Kennedy SH, Turecki G. Lopez JP, et al. Nat Commun. 2017 May 22;8:15497. doi: 10.1038/ncomms15497. Nat Commun. 2017. PMID: 28530238 Free PMC article. Clinical Trial.
These results were replicated in two independent clinical trials of MDD, a well-characterized animal model of depression, and post-mortem human brains. Furthermore, using a combination of bioinformatics, mRNA studies and functional in vitro experiments, we showed significa …
These results were replicated in two independent clinical trials of MDD, a well-characterized animal model of depression, and post-mortem hu …
Plasticity of the epigenome during early-life stress.
Burns SB, Szyszkowicz JK, Luheshi GN, Lutz PE, Turecki G. Burns SB, et al. Semin Cell Dev Biol. 2018 May;77:115-132. doi: 10.1016/j.semcdb.2017.09.033. Epub 2017 Oct 16. Semin Cell Dev Biol. 2018. PMID: 29017800 Review.
Noncoding RNAs in Depression.
Lin R, Turecki G. Lin R, et al. Adv Exp Med Biol. 2017;978:197-210. doi: 10.1007/978-3-319-53889-1_11. Adv Exp Med Biol. 2017. PMID: 28523548 Review.
The investigation of ncRNAs as regulators of gene expression has been a topic of growing interest in health research, including in studies investigating etiological and therapeutic factors in major depression. ...This review will detail the complex relation between ncRNAs …
The investigation of ncRNAs as regulators of gene expression has been a topic of growing interest in health research, including in studie …
Implication of LRRC4C and DPP6 in neurodevelopmental disorders.
Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NM, Blumenthal I, Chiang C, Ota V, Hultman C, O'Dushlaine C, McCarroll S, Alda M, Jacquemont S, Ordulu Z, Marshall CR, Carter MT, Shaffer LG, Sklar P, Girirajan S, Morton CC, Gusella JF, Turecki G, Stavropoulos DJ, Sullivan PF, Scherer SW, Talkowski ME, Ernst C. Maussion G, et al. Am J Med Genet A. 2017 Feb;173(2):395-406. doi: 10.1002/ajmg.a.38021. Epub 2016 Oct 19. Am J Med Genet A. 2017. PMID: 27759917 Free PMC article.
Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence.
Chandra R, Engeln M, Schiefer C, Patton MH, Martin JA, Werner CT, Riggs LM, Francis TC, McGlincy M, Evans B, Nam H, Das S, Girven K, Konkalmatt P, Gancarz AM, Golden SA, Iñiguez SD, Russo SJ, Turecki G, Mathur BN, Creed M, Dietz DM, Lobo MK. Chandra R, et al. Neuron. 2017 Dec 20;96(6):1327-1341.e6. doi: 10.1016/j.neuron.2017.11.037. Neuron. 2017. PMID: 29268097 Free PMC article.
Transcriptomic and epigenomic biomarkers of antidepressant response.
Belzeaux R, Lin R, Ju C, Chay MA, Fiori LM, Lutz PE, Turecki G. Belzeaux R, et al. J Affect Disord. 2018 Jun;233:36-44. doi: 10.1016/j.jad.2017.08.087. Epub 2017 Sep 8. J Affect Disord. 2018. PMID: 28918100 Review.
Secondly we synthesized results obtained in gene expression studies, focusing mainly on genome-wide studies, particularly small non-coding RNA, including micro-RNA and other small RNA species. In addition, we reviewed the potential biomarkers of antidepressant respo …
Secondly we synthesized results obtained in gene expression studies, focusing mainly on genome-wide studies, particularly smal …
Temperament and Character Profiles of Group-Based Suicide Cases.
Séguin M, Robert M, Beauchamp G. Séguin M, et al. Crisis. 2017 May;38(3):177-185. doi: 10.1027/0227-5910/a000430. Epub 2016 Oct 12. Crisis. 2017. PMID: 27733061
METHOD: A total of 90 cases of suicide decedents were analyzed using growth mixture modeling (GMM). ...CONCLUSION: Our results add to the literature by suggesting that different subgroups of suicide completers show a predisposition for either harm avoidance or self- …
METHOD: A total of 90 cases of suicide decedents were analyzed using growth mixture modeling (GMM). ...CONCLUSION: Our results add to …
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