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Year Number of Results
2017 13
2018 44
2019 2
2020 2
2021 0
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Comparative study of esketamine and racemic ketamine in treatment-resistant depression: Protocol for a non-inferiority clinical trial.
Correia-Melo FS, Leal GC, Carvalho MS, Jesus-Nunes AP, Ferreira CBN, Vieira F, Magnavita G, Vale LAS, Mello RP, Nakahira C, Argolo FC, Cardoso T, Souza CDS, Fontes ATC, Ferreira MB, Araújo-de-Freitas L, Tuena MA, Echegaray MVF, Cavalcanti DE, Lucchese AC, Bandeira ID, Telles M, Lima CS, Sampaio AS, Silva SS, Marback RF, Del-Porto JA, Abreu JN, Sarin LM, Paixão CS, Carvalho LP, Machado PRL, Turecki G, Lacerda ALT, Quarantini LC. Correia-Melo FS, et al. Medicine (Baltimore). 2018 Sep;97(38):e12414. doi: 10.1097/MD.0000000000012414. Medicine (Baltimore). 2018. PMID: 30235716 Free PMC article. Clinical Trial.
Esketamine, the S (+) enantiomer of ketamine, is the most widely used form in the anesthetic environment in some countries, and new studies have shown that it may also be effective in depression and with better tolerability. ...
Esketamine, the S (+) enantiomer of ketamine, is the most widely used form in the anesthetic environment in some countries, and new studi
Plasticity of the epigenome during early-life stress.
Burns SB, Szyszkowicz JK, Luheshi GN, Lutz PE, Turecki G. Burns SB, et al. Semin Cell Dev Biol. 2018 May;77:115-132. doi: 10.1016/j.semcdb.2017.09.033. Epub 2017 Oct 16. Semin Cell Dev Biol. 2018. PMID: 29017800 Review.
Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study.
Erlangsen A, Appadurai V, Wang Y, Turecki G, Mors O, Werge T, Mortensen PB, Starnawska A, Børglum AD, Schork A, Nudel R, Bækvad-Hansen M, Bybjerg-Grauholm J, Hougaard DM, Thompson WK, Nordentoft M, Agerbo E. Erlangsen A, et al. Mol Psychiatry. 2020 Oct;25(10):2410-2421. doi: 10.1038/s41380-018-0218-y. Epub 2018 Aug 16. Mol Psychiatry. 2020. PMID: 30116032 Free PMC article.
Family studies have shown an aggregation of suicidal behavior in families. ...After quality control, the sample consisted of 6024 cases with an incidence of suicide attempt and 44,240 controls with no record of a suicide attempt. ...
Family studies have shown an aggregation of suicidal behavior in families. ...After quality control, the sample consisted of 6024 cas …
Suicide and suicide behaviors: A review of transcriptomics and multiomics studies in psychiatric disorders.
Zhou Y, Lutz PE, Ibrahim EC, Courtet P, Tzavara E, Turecki G, Belzeaux R. Zhou Y, et al. J Neurosci Res. 2020 Apr;98(4):601-615. doi: 10.1002/jnr.24367. Epub 2018 Dec 18. J Neurosci Res. 2020. PMID: 30561057 Review.
Here, we review how transcriptomic approaches have deepened our understanding of the neurobiological underpinnings of psychiatric disorders and how they have to the identification of biomarkers for these disorders, with a focus on their relevance to suicide and suicide
Here, we review how transcriptomic approaches have deepened our understanding of the neurobiological underpinnings of psychiatric disorders …
Association between irritability and suicide-related outcomes across the life-course. Systematic review of both community and clinical studies.
Orri M, Perret LC, Turecki G, Geoffroy MC. Orri M, et al. J Affect Disord. 2018 Oct 15;239:220-233. doi: 10.1016/j.jad.2018.07.010. Epub 2018 Jul 4. J Affect Disord. 2018. PMID: 30025311
BACKGROUND: Irritability is gaining considerable attention as a risk factor for suicide-related outcomes (suicide mortality, attempt, and ideation). ...In both childhood/adolescence and adult samples, most community-based studies reported a positive associati …
BACKGROUND: Irritability is gaining considerable attention as a risk factor for suicide-related outcomes (suicide mortality, a …
Using Epigenetic Tools to Investigate Antidepressant Response.
Fiori LM, Lin R, Ju C, Belzeaux R, Turecki G. Fiori LM, et al. Prog Mol Biol Transl Sci. 2018;158:255-272. doi: 10.1016/bs.pmbts.2018.04.004. Epub 2018 May 29. Prog Mol Biol Transl Sci. 2018. PMID: 30072056 Review.
In this chapter, we review key methodological considerations when investigating ncRNA biomarkers, including biological samples and technologies which have been used in these studies. Secondly, we summarize findings from studies investigating ncRNAs in antidepressant …
In this chapter, we review key methodological considerations when investigating ncRNA biomarkers, including biological samples and technolog …
Transcriptomic and epigenomic biomarkers of antidepressant response.
Belzeaux R, Lin R, Ju C, Chay MA, Fiori LM, Lutz PE, Turecki G. Belzeaux R, et al. J Affect Disord. 2018 Jun;233:36-44. doi: 10.1016/j.jad.2017.08.087. Epub 2017 Sep 8. J Affect Disord. 2018. PMID: 28918100 Review.
Secondly we synthesized results obtained in gene expression studies, focusing mainly on genome-wide studies, particularly small non-coding RNA, including micro-RNA and other small RNA species. In addition, we reviewed the potential biomarkers of antidepressant respo …
Secondly we synthesized results obtained in gene expression studies, focusing mainly on genome-wide studies, particularly smal …
Increased Risk of Rehospitalization for Acute Diabetes Complications and Suicide Attempts in Patients With Type 1 Diabetes and Comorbid Schizophrenia.
Goueslard K, Petit JM, Cottenet J, Chauvet-Gelinier JC, Jollant F, Quantin C. Goueslard K, et al. Diabetes Care. 2018 Nov;41(11):2316-2321. doi: 10.2337/dc18-0657. Epub 2018 Aug 27. Diabetes Care. 2018. PMID: 30150237
The association between hospitalization for suicide attempts and acute diabetes complications was further explored in a survival analysis, with the exposure of acute diabetes complications as a time-dependent covariate. ...Hospitalization for a suicide attempt was a …
The association between hospitalization for suicide attempts and acute diabetes complications was further explored in a survival anal …
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