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1982 1
1989 1
1990 3
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1992 5
1993 9
1994 22
1995 18
1996 26
1997 30
1998 27
1999 37
2000 34
2001 43
2002 44
2003 58
2004 73
2005 76
2006 77
2007 75
2008 86
2009 84
2010 65
2011 81
2012 88
2013 76
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2015 58
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2019 21
2020 27
2021 20
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1,339 results
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MDA-MB-435: the questionable use of a melanoma cell line as a model for human breast cancer is ongoing.
Christgen M, Lehmann U. Christgen M, et al. Cancer Biol Ther. 2007 Sep;6(9):1355-7. doi: 10.4161/cbt.6.9.4624. Epub 2007 Jun 23. Cancer Biol Ther. 2007. PMID: 17786032 Review.
In September 2006, Rae et al. provided unmistakable evidence that the MDA-MB-435 human breast cancer cell line is identical to the M14 human melanoma cell line. ...In fact, the expression of melanocyte-specific marker proteins by MDA-MB-435 …
In September 2006, Rae et al. provided unmistakable evidence that the MDA-MB-435 human breast cancer cell line is ident …
Antiproliferative effect of guava fruit extracts in MDA-MB-435 and MCF-7 human breast cancer cell lines.
Correa MG, Couto JS, Trindade BB, Abreu JP, Nakajima VM, Oliveira FL, Farah A, Teodoro AJ. Correa MG, et al. An Acad Bras Cienc. 2020;92(2):e20191500. doi: 10.1590/0001-3765202020191500. Epub 2020 Aug 12. An Acad Bras Cienc. 2020. PMID: 32813860 Free article.
After 48 hours treatment, all guava cultivars' extracts caused reduction of MDA-MB-435 and MCF-7 cells viability, with PS and HI being the most effective extracts. All guava extracts caused MDA-MB-435 and MCF-7 cell count reduction in G0/ …
After 48 hours treatment, all guava cultivars' extracts caused reduction of MDA-MB-435 and MCF-7 cells viability, with …
Authentication of M14 melanoma cell line proves misidentification of MDA-MB-435 breast cancer cell line.
Korch C, Hall EM, Dirks WG, Ewing M, Faries M, Varella-Garcia M, Robinson S, Storts D, Turner JA, Wang Y, Burnett EC, Healy L, Kniss D, Neve RM, Nims RW, Reid YA, Robinson WA, Capes-Davis A. Korch C, et al. Int J Cancer. 2018 Feb 1;142(3):561-572. doi: 10.1002/ijc.31067. Epub 2017 Oct 10. Int J Cancer. 2018. PMID: 28940260 Free PMC article.
Initial studies concluded that MDA-MB-435 was the misidentified cell line and M14 was the authentic cell line, although contradictory evidence has been published, resulting in further confusion. To address this question, we obtained early samples of the melan …
Initial studies concluded that MDA-MB-435 was the misidentified cell line and M14 was the authentic cell line, although …
Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties.
Rae JM, Ramus SJ, Waltham M, Armes JE, Campbell IG, Clarke R, Barndt RJ, Johnson MD, Thompson EW. Rae JM, et al. Clin Exp Metastasis. 2004;21(6):543-52. doi: 10.1007/s10585-004-3759-1. Clin Exp Metastasis. 2004. PMID: 15679052 Free article.
In this study, we set out to determine whether MDA-MB-435-DTP cells shown to express melanoma-specific genes were identical to various other MDA-MB-435 cell stocks worldwide. ...Gene expression profile analysis confirmed common expression …
In this study, we set out to determine whether MDA-MB-435-DTP cells shown to express melanoma-specific genes were ident …
MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research.
Rae JM, Creighton CJ, Meck JM, Haddad BR, Johnson MD. Rae JM, et al. Breast Cancer Res Treat. 2007 Jul;104(1):13-9. doi: 10.1007/s10549-006-9392-8. Epub 2006 Sep 27. Breast Cancer Res Treat. 2007. PMID: 17004106
We have previously shown that MDA-MB-435 cells maintained in multiple laboratories are of common origin to those used by Ross et al. and concluded that MDA-MB-435 cells are not a representative model for breast cancer. ...CONCLUSIONS: All …
We have previously shown that MDA-MB-435 cells maintained in multiple laboratories are of common origin to those used b …
LCC15-MB cells are MDA-MB-435: a review of misidentified breast and prostate cell lines.
Thompson EW, Waltham M, Ramus SJ, Hutchins AM, Armes JE, Campbell IG, Williams ED, Thompson PR, Rae JM, Johnson MD, Clarke R. Thompson EW, et al. Clin Exp Metastasis. 2004;21(6):535-41. doi: 10.1007/s10585-004-4117-z. Clin Exp Metastasis. 2004. PMID: 15679051
The original karyotype reported for LCC15-MB cells was considerably different to that of MDA-MB-435 cells, indicating that the original LCC15-MB cells were lost to contamination by MDA-MB-435-LCC cells. ...Collectively, our …
The original karyotype reported for LCC15-MB cells was considerably different to that of MDA-MB-435 cells, indic …
MDA-MB-435 and M14 cell lines: identical but not M14 melanoma?
Chambers AF. Chambers AF. Cancer Res. 2009 Jul 1;69(13):5292-3. doi: 10.1158/0008-5472.CAN-09-1528. Epub 2009 Jun 23. Cancer Res. 2009. PMID: 19549886 Free article.
A controversy has arisen over the past several years about the true origin of the human MDA-MB-435 cell line. Originally described as a human breast cancer cell line, subsequent expression array studies instead suggested a gene expression profile consistent w …
A controversy has arisen over the past several years about the true origin of the human MDA-MB-435 cell line. Originall …
Ectopic expression of KLK6 in MDA-MB-435 melanoma cells reduces tumorigenicity in vivo.
Pampalakis G, Zingkou E, Zoumpourlis V, Sotiropoulou G. Pampalakis G, et al. Pathol Res Pract. 2021 Jan;217:153276. doi: 10.1016/j.prp.2020.153276. Epub 2020 Nov 14. Pathol Res Pract. 2021. PMID: 33249398
To delineate putative roles of KLK6 in melanoma, the invasive KLK6-non-expressing MDA-MB-435 melanoma cell line was stably transfected with the full-length KLK6 cDNA and expression of the corresponding RNA and protein were confirmed. ...
To delineate putative roles of KLK6 in melanoma, the invasive KLK6-non-expressing MDA-MB-435 melanoma cell line was sta …
1,2,3-Triazole tethered 1,2,4-trioxanes: Studies on their synthesis and effect on osteopontin expression in MDA-MB-435 breast cancer cells.
Pasupuleti BG, Khongsti K, Das B, Bez G. Pasupuleti BG, et al. Eur J Med Chem. 2020 Jan 15;186:111908. doi: 10.1016/j.ejmech.2019.111908. Epub 2019 Nov 27. Eur J Med Chem. 2020. PMID: 31791643
Given the high antitumor activity of artemisinin dimers in comparison to their monomers, we report here the synthesis of simple 1,2,3-triazole conjugated 1,2,4-trioxanes and their potential antitumor activity by studying their inhibitory effect on osteopontin (OPN) expression in …
Given the high antitumor activity of artemisinin dimers in comparison to their monomers, we report here the synthesis of simple 1,2,3-triazo …
MDA-MB-435 cells are from melanoma, not from breast cancer.
Lacroix M. Lacroix M. Cancer Chemother Pharmacol. 2009 Feb;63(3):567. doi: 10.1007/s00280-008-0776-9. Epub 2008 May 24. Cancer Chemother Pharmacol. 2009. PMID: 18500520
For years, MDA-MB-435 cells have been widely but erroneously used as breast cancer cells with aggressive behaviour. ...
For years, MDA-MB-435 cells have been widely but erroneously used as breast cancer cells with aggressive behaviour. ...
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