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MDMA interactions with pharmaceuticals and drugs of abuse.
Papaseit E, Pérez-Mañá C, Torrens M, Farré A, Poyatos L, Hladun O, Sanvisens A, Muga R, Farré M. Papaseit E, et al. Expert Opin Drug Metab Toxicol. 2020 May;16(5):357-369. doi: 10.1080/17425255.2020.1749262. Epub 2020 Apr 12. Expert Opin Drug Metab Toxicol. 2020. PMID: 32228243 Review.
Thus, MDMA-drug interactions (MDMA-DIs) lead to a higher risk of acute and life-threatening MDMA toxicity.Areas covered: This article provides an overview of the MDMA-DIs with pharmaceuticals and drugs of abuse. ...Experimental evidence points out the …
Thus, MDMA-drug interactions (MDMA-DIs) lead to a higher risk of acute and life-threatening MDMA toxicity.Areas covered …
Neurotoxicity of MDMA: Main effects and mechanisms.
Costa G, Gołembiowska K. Costa G, et al. Exp Neurol. 2022 Jan;347:113894. doi: 10.1016/j.expneurol.2021.113894. Epub 2021 Oct 13. Exp Neurol. 2022. PMID: 34655576 Review.
Preclinical and clinical studies indicate that 3,4-methylenedioxymethamphetamine (MDMA; 'ecstasy'), in addition to having abuse potential, may elicit acute and persistent abnormalities of varying severity at the central level. Importantly, neurotoxic effects of MDMA …
Preclinical and clinical studies indicate that 3,4-methylenedioxymethamphetamine (MDMA; 'ecstasy'), in addition to having abuse poten …
MDMA-Assisted Psychotherapy for Treatment of Posttraumatic Stress Disorder: A Systematic Review With Meta-Analysis.
Smith KW, Sicignano DJ, Hernandez AV, White CM. Smith KW, et al. J Clin Pharmacol. 2022 Apr;62(4):463-471. doi: 10.1002/jcph.1995. Epub 2021 Nov 28. J Clin Pharmacol. 2022. PMID: 34708874
In MDMA-assisted psychotherapy, patients are subjected to 2 or 3 multihour sessions of therapy with a team of psychiatrists. The dosing of MDMA is used to allow the therapist to probe the underlying trauma without causing emotional distress. ...
In MDMA-assisted psychotherapy, patients are subjected to 2 or 3 multihour sessions of therapy with a team of psychiatrists. The dosi …
[MDMA-assisted therapy for PTSD].
Thorarinsdottir H, Gudmundsdottir B, Sigurdsson E. Thorarinsdottir H, et al. Laeknabladid. 2024 May;110(5):254-261. doi: 10.17992/lbl.2024.05.793. Laeknabladid. 2024. PMID: 38713560 Review. Icelandic.
MDMA is a potential novel treatment for post-traumatic stress disorder (PTSD). Our goal is to review current knowledge on MDMA and its use in MDMA-assisted psychotherapy for PTSD. ...There is an urgent need for new effective treatments for PTSD and for compar …
MDMA is a potential novel treatment for post-traumatic stress disorder (PTSD). Our goal is to review current knowledge on MDMA …
MDMA related neuro-inflammation and adenosine receptors.
Kermanian F, Seghatoleslam M, Mahakizadeh S. Kermanian F, et al. Neurochem Int. 2022 Feb;153:105275. doi: 10.1016/j.neuint.2021.105275. Epub 2022 Jan 3. Neurochem Int. 2022. PMID: 34990730 Review.
3,4-methylenedioxymethamphetamine (MDMA) is a world-wide abused psychostimulant, which has the neurotoxic effects on dopaminergic and serotonergic neurons in both rodents and non-human primates. ...This review summarizes the specific cellular mechanisms involved in MDMA …
3,4-methylenedioxymethamphetamine (MDMA) is a world-wide abused psychostimulant, which has the neurotoxic effects on dopaminergic and …
The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents.
Freudenmann RW, Oxler F, Bernschneider-Reif S. Freudenmann RW, et al. Addiction. 2006 Sep;101(9):1241-5. doi: 10.1111/j.1360-0443.2006.01511.x. Addiction. 2006. PMID: 16911722
BACKGROUND: Little is known about the origin of methylenedioxymethamphetamine (MDMA, ecstasy). The most commonly repeated statement in the medical literature is that MDMA was synthesized by the German pharmaceutical company Merck in 1912 in order to develop an appet …
BACKGROUND: Little is known about the origin of methylenedioxymethamphetamine (MDMA, ecstasy). The most commonly repeated statement i …
Mephedrone and MDMA: A comparative review.
Mead J, Parrott A. Mead J, et al. Brain Res. 2020 May 15;1735:146740. doi: 10.1016/j.brainres.2020.146740. Epub 2020 Feb 19. Brain Res. 2020. PMID: 32087112 Review.
Mephedrone and MDMA are both constituents of party drugs, with mephedrone being relatively new compared to MDMA. ...Whilst there is extensive research into the psychobiological problems induced by MDMA, the evidence for mephedrone is comparatively limited. Th …
Mephedrone and MDMA are both constituents of party drugs, with mephedrone being relatively new compared to MDMA. ...Whilst the …
Methylenedioxymethamphetamine (MDMA): Serotonergic and dopaminergic mechanisms related to its use and misuse.
Schenk S, Highgate Q. Schenk S, et al. J Neurochem. 2021 Jun;157(5):1714-1724. doi: 10.1111/jnc.15348. Epub 2021 Mar 25. J Neurochem. 2021. PMID: 33711169 Free article. Review.
The ratio of drug-stimulated increases in synaptic DA, relative to 5HT, predicts the abuse liability; drugs with higher DA:5HT ratios are more likely to be abused. Nonetheless, MDMA is a drug that is misused. Clinical and preclinical studies have suggested that repeated …
The ratio of drug-stimulated increases in synaptic DA, relative to 5HT, predicts the abuse liability; drugs with higher DA:5HT ratios are mo …
Methylenedioxymethamphetamine (MDMA) in Psychiatry: Pros, Cons, and Suggestions.
Schenk S, Newcombe D. Schenk S, et al. J Clin Psychopharmacol. 2018 Dec;38(6):632-638. doi: 10.1097/JCP.0000000000000962. J Clin Psychopharmacol. 2018. PMID: 30303861 Review.
METHODS: In this article, the proposed potential of MDMA as an adjunct to psychotherapy for PTSD is evaluated. The rationale for the use of MDMA and the positive results of studies that have administered MDMA in the treatment of PTSD are provided (pros). ...R …
METHODS: In this article, the proposed potential of MDMA as an adjunct to psychotherapy for PTSD is evaluated. The rationale for the …
MDMA (Ecstasy).
El-Mallakh RS, Abraham HD. El-Mallakh RS, et al. Ann Clin Psychiatry. 2007 Jan-Mar;19(1):45-52. doi: 10.1080/10401230601163592. Ann Clin Psychiatry. 2007. PMID: 17453661 Review.
RESULTS: A significant body of literature suggests that the patterns of MDMA use differ from traditional drugs of abuse, with relatively uncommon dependence and escalation of dosage. Nonetheless, MDMA is also neurotoxic with significant deleterious effects on seroto …
RESULTS: A significant body of literature suggests that the patterns of MDMA use differ from traditional drugs of abuse, with relativ …
6,703 results