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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1979 1
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1985 3
1987 1
1988 3
1989 1
1990 3
1991 1
1992 2
1993 5
1994 12
1995 5
1996 15
1997 19
1998 11
1999 23
2000 12
2001 14
2002 31
2003 20
2004 26
2005 30
2006 41
2007 23
2008 34
2009 39
2010 43
2011 60
2012 58
2013 54
2014 62
2015 62
2016 77
2017 92
2018 84
2019 79
2020 157
2021 141
2022 141
2023 141
2024 146
2025 194
2026 119

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1,861 results

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Page 1
Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial.
Walsh TS, Parker RA, Aitken LM, McKenzie CA, Emerson L, Boyd J, Macdonald A, Beveridge G, Giddings A, Hope D, Irvine S, Tuck S, Lone NI, Kydonaki K, Norrie J, Brealey D, Antcliffe D, Reay M, Williams A, Bewley J, Creagh-Brown B, McAuley DF, Dark P, Wise MP, Gordon AC, Perkins GD, Reade MC, Blackwood B, MacLullich A, Glen R, Page VJ, Weir CJ; A2B Trial Investigators. Walsh TS, et al. JAMA. 2025 Jul 1;334(1):32-45. doi: 10.1001/jama.2025.7200. JAMA. 2025. PMID: 40388916 Free PMC article. Clinical Trial.
IMPORTANCE: Whether alpha2-adrenergic receptor agonist-based sedation, compared with propofol-based sedation, reduces time to extubation in patients receiving mechanical ventilation in the intensive care unit (ICU) is uncertain. OBJECTIVE: To ev …
IMPORTANCE: Whether alpha2-adrenergic receptor agonist-based sedation, compared with propofol-based sedation, reduces time to extubation …
Noninvasive respiratory supports in ICU.
Frat JP, Grieco DL, De Jong A, Gibbs K, Carteaux G, Roca O, Lemiale V, Piquilloud L, Rittayamai N, Pisani L, Hernandez G, Thille AW. Frat JP, et al. Intensive Care Med. 2025 Aug;51(8):1476-1489. doi: 10.1007/s00134-025-08036-3. Epub 2025 Jul 24. Intensive Care Med. 2025. PMID: 40705073 Free article. Review.
BACKGROUND: Noninvasive respiratory supports are routinely applied in critically ill patients with acute respiratory failure to avoid intubation and invasive mechanical ventilation, thereby reducing the risk of related complications, and to faci …
BACKGROUND: Noninvasive respiratory supports are routinely applied in critically ill patients with acute respiratory failur …
Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC).
Kneyber MCJ, de Luca D, Calderini E, Jarreau PH, Javouhey E, Lopez-Herce J, Hammer J, Macrae D, Markhorst DG, Medina A, Pons-Odena M, Racca F, Wolf G, Biban P, Brierley J, Rimensberger PC; section Respiratory Failure of the European Society for Paediatric and Neonatal Intensive Care. Kneyber MCJ, et al. Intensive Care Med. 2017 Dec;43(12):1764-1780. doi: 10.1007/s00134-017-4920-z. Epub 2017 Sep 22. Intensive Care Med. 2017. PMID: 28936698 Free PMC article.
PURPOSE: Much of the common practice in paediatric mechanical ventilation is based on personal experiences and what paediatric critical care practitioners have adopted from adult and neonatal experience. ...We aim to establish a European consensus guid …
PURPOSE: Much of the common practice in paediatric mechanical ventilation is based on personal experiences and what paediatric …
Prediction of extubation outcome in critically ill patients: a systematic review and meta-analysis.
Torrini F, Gendreau S, Morel J, Carteaux G, Thille AW, Antonelli M, Mekontso Dessap A. Torrini F, et al. Crit Care. 2021 Nov 15;25(1):391. doi: 10.1186/s13054-021-03802-3. Crit Care. 2021. PMID: 34782003 Free PMC article.
We included observational studies involving risk factors associated with extubation failure in adult intensive care unit patients who underwent invasive mechanical ventilation. ...CONCLUSIONS: Numerous factors are associated with extub …
We included observational studies involving risk factors associated with extubation failure in adult intensive care …
Update on ventilation management in the Pediatric Intensive Care Unit.
Egbuta C, Easley RB. Egbuta C, et al. Paediatr Anaesth. 2022 Feb;32(2):354-362. doi: 10.1111/pan.14374. Epub 2021 Dec 15. Paediatr Anaesth. 2022. PMID: 34882910 Review.
Studies have shown that up to 63% of pediatric intensive care unit patients admitted with acute respiratory or cardiorespiratory illness require mechanical ventilation. ...Nonconventional modes of ventilation in the intensive ca …
Studies have shown that up to 63% of pediatric intensive care unit patients admitted with acute respiratory or cardiorespirato …
Extubation in neurocritical care patients: the ENIO international prospective study.
Cinotti R, Mijangos JC, Pelosi P, Haenggi M, Gurjar M, Schultz MJ, Kaye C, Godoy DA, Alvarez P, Ioakeimidou A, Ueno Y, Badenes R, Suei Elbuzidi AA, Piagnerelli M, Elhadi M, Reza ST, Azab MA, McCredie V, Stevens RD, Digitale JC, Fong N, Asehnoune K; ENIO Study Group, the PROtective VENTilation network, the European Society of Intensive Care Medicine, the Colegio Mexicano de Medicina Critica, the Atlanréa group and the Société Française d’Anesthésie-Réanimation–SFAR research network. Cinotti R, et al. Intensive Care Med. 2022 Nov;48(11):1539-1550. doi: 10.1007/s00134-022-06825-8. Epub 2022 Aug 29. Intensive Care Med. 2022. PMID: 36038713
PURPOSE: Neurocritical care patients receive prolonged invasive mechanical ventilation (IMV), but there is poor specific information in this high-risk population about the liberation strategies of invasive mechanical ventilation. ...CONCLUSIONS: …
PURPOSE: Neurocritical care patients receive prolonged invasive mechanical ventilation (IMV), but there is poor specifi …
Continued enteral nutrition until extubation compared with fasting before extubation in patients in the intensive care unit: an open-label, cluster-randomised, parallel-group, non-inferiority trial.
Landais M, Nay MA, Auchabie J, Hubert N, Frerou A, Yehia A, Mercat A, Jonas M, Martino F, Moriconi M, Courte A, Robert-Edan V, Conia A, Bavozet F, Egreteau PY, Bruel C, Renault A, Huet O, Feller M, Chudeau N, Ferrandiere M, Rebion A, Robert A, Giraudeau B, Reignier J, Thille AW, Tavernier E, Ehrmann S; REVA network and CRICS-TriggerSEP F-CRIN research network. Landais M, et al. Lancet Respir Med. 2023 Apr;11(4):319-328. doi: 10.1016/S2213-2600(22)00413-1. Epub 2023 Jan 21. Lancet Respir Med. 2023. PMID: 36693402 Free article. Clinical Trial.
METHODS: We conducted an open-label, cluster-randomised, parallel-group, non-inferiority trial in 22 intensive care units in France. Patients aged 18 years or older were eligible for enrolment if they had received invasive mechanical ventilation for at …
METHODS: We conducted an open-label, cluster-randomised, parallel-group, non-inferiority trial in 22 intensive care units in F …
Effect of postextubation noninvasive ventilation with active humidification vs high-flow nasal cannula on reintubation in patients at very high risk for extubation failure: a randomized trial.
Hernández G, Paredes I, Moran F, Buj M, Colinas L, Rodríguez ML, Velasco A, Rodríguez P, Pérez-Pedrero MJ, Suarez-Sipmann F, Canabal A, Cuena R, Blanch L, Roca O. Hernández G, et al. Intensive Care Med. 2022 Dec;48(12):1751-1759. doi: 10.1007/s00134-022-06919-3. Epub 2022 Nov 18. Intensive Care Med. 2022. PMID: 36400984 Free PMC article. Clinical Trial.
Patients ready for planned extubation with 4 of the following risk factors for reintubation were included: age > 65 years, Acute Physiology and Chronic Health Evaluation II score > 12 on extubation day, body mass index > 30, inadequate secretions manageme …
Patients ready for planned extubation with 4 of the following risk factors for reintubation were included: age > 65 years, Acute …
Review of Ventilation in Traumatic Brain Injury.
Becker ER, Wetmore GC, Goodman MD, Rodriquez D Jr, Branson RD. Becker ER, et al. Respir Care. 2025 Apr;70(4):450-457. doi: 10.1089/respcare.12796. Epub 2025 Feb 12. Respir Care. 2025. PMID: 40028858 Free PMC article. Review.
Acute brain injury is a prominent admitting diagnosis of critically ill patients, often requiring endotracheal intubation to protect the airway and resulting in respiratory failure and the need for mechanical ventilation. ...This review d …
Acute brain injury is a prominent admitting diagnosis of critically ill patients, often requiring endotracheal intubation to p …
Frequency of Screening and Spontaneous Breathing Trial Techniques: A Randomized Clinical Trial.
Burns KEA, Wong J, Rizvi L, Lafreniere-Roula M, Thorpe K, Devlin JW, Cook DJ, Seely A, Dodek PM, Tanios M, Piraino T, Gouskos A, Kiedrowski KC, Kay P, Mitchell S, Merner GW, Mayette M, D'Aragon F, Lamontagne F, Rochwerg B, Turgeon A, Sia YT, Charbonney E, Aslanian P, Criner GJ, Hyzy RC, Beitler JR, Kassis EB, Kutsogiannis DJ, Meade MO, Liebler J, Iyer-Kumar S, Tsang J, Cirone R, Shanholtz C, Hill NS; Canadian Critical Care Trials Group. Burns KEA, et al. JAMA. 2024 Dec 3;332(21):1808-1821. doi: 10.1001/jama.2024.20631. JAMA. 2024. PMID: 39382222 Free PMC article. Clinical Trial.
OBJECTIVE: To compare the effects of screening frequency (once-daily screening vs more frequent screening) and SBT technique (pressure-supported SBT with a pressure support level that was >0- 8 cm H2O and a positive end-expiratory pressure [PEEP] level that was >0- 5 cm H2O …
OBJECTIVE: To compare the effects of screening frequency (once-daily screening vs more frequent screening) and SBT technique (pressure-suppo …
1,861 results