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Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials.
Venturella G, Ferraro V, Cirlincione F, Gargano ML. Venturella G, et al. Int J Mol Sci. 2021 Jan 10;22(2):634. doi: 10.3390/ijms22020634. Int J Mol Sci. 2021. PMID: 33435246 Free PMC article. Review.
Medicinal mushrooms have important health benefits and exhibit a broad spectrum of pharmacological activities, including antiallergic, antibacterial, antifungal, anti-inflammatory, antioxidative, antiviral, cytotoxic, immunomodulating, antidepressive, antihyp …
Medicinal mushrooms have important health benefits and exhibit a broad spectrum of pharmacological activities, including antia …
Proteins with antifungal properties and other medicinal applications from plants and mushrooms.
Wong JH, Ng TB, Cheung RC, Ye XJ, Wang HX, Lam SK, Lin P, Chan YS, Fang EF, Ngai PH, Xia LX, Ye XY, Jiang Y, Liu F. Wong JH, et al. Appl Microbiol Biotechnol. 2010 Jul;87(4):1221-35. doi: 10.1007/s00253-010-2690-4. Epub 2010 Jun 8. Appl Microbiol Biotechnol. 2010. PMID: 20532758 Review.
In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins have been reported. Mushroom antifungal proteins are distinct from their plant counterparts in N-terminal sequence. ...
In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins ha …
Antifungal Activity of Medicinal Mushrooms and Optimization of Submerged Culture Conditions for Schizophyllum commune (Agaricomycetes).
Berikashvili V, Khardziani T, Kobakhidze A, Kulp M, Kuhtinskaja M, Lukk T, Gargano ML, Venturella G, Kachlishvili E, Metreveli E, Elisashvili VI, Asatiani M. Berikashvili V, et al. Int J Med Mushrooms. 2023;25(10):1-21. doi: 10.1615/IntJMedMushrooms.2023049836. Int J Med Mushrooms. 2023. PMID: 37830193
The main goal of the present study was the exploration of the antifungal properties of Agaricomycetes mushrooms. Among twenty-three tested mushrooms against A. niger, B. cinerea, F. oxysporum, and G. bidwellii, Schizophyllum commune demonstrated highest inhib …
The main goal of the present study was the exploration of the antifungal properties of Agaricomycetes mushrooms. Among twenty- …
Fungal impacts on Earth's ecosystems.
Case NT, Gurr SJ, Fisher MC, Blehert DS, Boone C, Casadevall A, Chowdhary A, Cuomo CA, Currie CR, Denning DW, Ene IV, Fritz-Laylin LK, Gerstein AC, Gow NAR, Gusa A, Iliev ID, James TY, Jin H, Kahmann R, Klein BS, Kronstad JW, Ost KS, Peay KG, Shapiro RS, Sheppard DC, Shlezinger N, Stajich JE, Stukenbrock EH, Taylor JW, Wright GD, Cowen LE, Heitman J, Segre JA. Case NT, et al. Nature. 2025 Feb;638(8049):49-57. doi: 10.1038/s41586-024-08419-4. Epub 2025 Feb 5. Nature. 2025. PMID: 39910383 Free PMC article. Review.
Over the past billion years, the fungal kingdom has diversified to more than two million species, with over 95% still undescribed. Beyond the well-known macroscopic mushrooms and microscopic yeast, fungi are heterotrophs that feed on almost any organic carbon, recycling nu …
Over the past billion years, the fungal kingdom has diversified to more than two million species, with over 95% still undescribed. Beyond th …
A Review on Phytochemistry and Pharmacology of Medicinal as well as Poisonous Mushrooms.
Sharma D, Singh VP, Singh NK. Sharma D, et al. Mini Rev Med Chem. 2018;18(13):1095-1109. doi: 10.2174/1389557517666170927144119. Mini Rev Med Chem. 2018. PMID: 28971768 Review.
Mushrooms have been used as traditional medicine from last few decades. Mushrooms as higher Basidiomycetes contain secondary metabolites in fruit bodies, cultured mycelium, and cultured broth. Medicinal mushrooms possess medicinal propert …
Mushrooms have been used as traditional medicine from last few decades. Mushrooms as higher Basidiomycetes contain seco …
Medicinal Mushrooms in Human Clinical Studies. Part I. Anticancer, Oncoimmunological, and Immunomodulatory Activities: A Review.
Wasser SP. Wasser SP. Int J Med Mushrooms. 2017;19(4):279-317. doi: 10.1615/IntJMedMushrooms.v19.i4.10. Int J Med Mushrooms. 2017. PMID: 28605319 Review.
More than 130 medicinal functions are thought to be produced by medicinal mushrooms (MMs) and fungi, including antitumor, immunomodulating, antioxidant, radical scavenging, cardiovascular, antihypercholesterolemic, antiviral, antibacterial, antiparasitic, …
More than 130 medicinal functions are thought to be produced by medicinal mushrooms (MMs) and fungi, including antitumo …
Medicinal Coprinoid Mushrooms (Agaricomycetes) Distributed in Armenia (Review).
Badalyan SM. Badalyan SM. Int J Med Mushrooms. 2020;22(3):257-267. doi: 10.1615/IntJMedMushrooms.2020033981. Int J Med Mushrooms. 2020. PMID: 32479020 Review.
The coprinoid mushrooms or coprini are species of former genus Coprinus Pers. (Coprinaceae, Agaricomycetes) currently divided into four new genera: Coprinus, Coprinopsis, Coprinellus, and Parasola. The presented review addresses literature data and findings from our recent …
The coprinoid mushrooms or coprini are species of former genus Coprinus Pers. (Coprinaceae, Agaricomycetes) currently divided into fo …
Cordycepin and kinase inhibition in cancer.
Khan MA, Tania M. Khan MA, et al. Drug Discov Today. 2023 Mar;28(3):103481. doi: 10.1016/j.drudis.2022.103481. Epub 2022 Dec 27. Drug Discov Today. 2023. PMID: 36584876 Review.
Cordycepin, a nucleoside from Cordyceps mushrooms, has many beneficial properties for health, including anticancer activities. In cancer cells, cordycepin targets various signaling molecules. ...
Cordycepin, a nucleoside from Cordyceps mushrooms, has many beneficial properties for health, including anticancer activities. In can …
Research Progress of Bioactive Proteins from the Edible and Medicinal Mushrooms.
Zhou R, Liu ZK, Zhang YN, Wong JH, Ng TB, Liu F. Zhou R, et al. Curr Protein Pept Sci. 2019;20(3):196-219. doi: 10.2174/1389203719666180613090710. Curr Protein Pept Sci. 2019. PMID: 29895245 Review.
For centuries, mushrooms have been widely used as traditional Chinese medicine in Asia. Apart from polysaccharides and some small-molecule components, such as flavones, polyphenols and terpenes, mushrooms produce a large number of pharmaceutically active prot …
For centuries, mushrooms have been widely used as traditional Chinese medicine in Asia. Apart from polysaccharides and some sm …
The alkynyl-containing compounds from mushrooms and their biological activities.
Qi JS, Duan Y, Li ZC, Gao JM, Qi J, Liu C. Qi JS, et al. Nat Prod Bioprospect. 2023 Nov 10;13(1):50. doi: 10.1007/s13659-023-00416-w. Nat Prod Bioprospect. 2023. PMID: 37946001 Free PMC article. Review.
Mushrooms have been utilized by humans for thousands of years due to their medicinal and nutritional properties. ...This review serves as a detailed and comprehensive reference for the chemical structures and bioactivity of alkynyl-containing secondary metabolites f …
Mushrooms have been utilized by humans for thousands of years due to their medicinal and nutritional properties. ...This revie …
Current findings, future trends, and unsolved problems in studies of medicinal mushrooms.
Wasser SP. Wasser SP. Appl Microbiol Biotechnol. 2011 Mar;89(5):1323-32. doi: 10.1007/s00253-010-3067-4. Epub 2010 Dec 29. Appl Microbiol Biotechnol. 2011. PMID: 21190105 Review.
The target of the present review is to draw attention to many critically important unsolved problems in the future development of medicinal mushroom science in the twenty-first century. Special attention is paid to mushroom polysaccharides. ...A total of 126 …
The target of the present review is to draw attention to many critically important unsolved problems in the future development of medicin …
Biomolecules of mushroom: a recipe of human wellness.
Singh MP, Rai SN, Dubey SK, Pandey AT, Tabassum N, Chaturvedi VK, Singh NB. Singh MP, et al. Crit Rev Biotechnol. 2022 Sep;42(6):913-930. doi: 10.1080/07388551.2021.1964431. Epub 2021 Aug 19. Crit Rev Biotechnol. 2022. PMID: 34412526 Review.
The Indian system of medicine - Ayurveda says "When diet is wrong, medicine is of no use. When diet is correct, medicine is of no use". In this context, mushroom constitutes one of the major resources for nutraceuticals. Biomolecules of mushrooms …
The Indian system of medicine - Ayurveda says "When diet is wrong, medicine is of no use. When diet is correct, medicine …
The Health-promoting Potential of Edible Mushroom Proteins.
Sousa AS, Araújo-Rodrigues H, Pintado ME. Sousa AS, et al. Curr Pharm Des. 2023;29(11):804-823. doi: 10.2174/1381612829666221223103756. Curr Pharm Des. 2023. PMID: 36567303 Review.
Edible mushrooms have been classified as "next-generation food" due to their high nutritional value coupled with their biological and functional potential. ...These are reported as antioxidant, antiviral, antifungal, antibacterial, antihypertensive, immunomodulatory …
Edible mushrooms have been classified as "next-generation food" due to their high nutritional value coupled with their biological and …
Medicinal mushroom science: Current perspectives, advances, evidences, and challenges.
Wasser SP. Wasser SP. Biomed J. 2014 Nov-Dec;37(6):345-56. doi: 10.4103/2319-4170.138318. Biomed J. 2014. PMID: 25179726 Free article. Review.
The main target of the present review is to draw attention to the current perspectives, advances, evidences, challenges, and future development of medicinal mushroom science in the 21 st century. Medicinal mushrooms and fungi are thought to possess app …
The main target of the present review is to draw attention to the current perspectives, advances, evidences, challenges, and future developm …
Bioprospecting of Wild Mushrooms from India with Respect to Their Medicinal Aspects.
Khan F, Chandra R. Khan F, et al. Int J Med Mushrooms. 2019;21(2):181-192. doi: 10.1615/IntJMedMushrooms.2019029969. Int J Med Mushrooms. 2019. PMID: 30806224
The forest region of the Ranchi District of Jharkhand, India, is rich with various wild mushrooms. Of the 200 samples collected, 9 species were identified and subjected to medicinal studies. For antibacterial assay, 4 strains of bacteria (namely, Escherichia coli, S …
The forest region of the Ranchi District of Jharkhand, India, is rich with various wild mushrooms. Of the 200 samples collected, 9 sp …
Benzothiazole-An Antifungal Compound Derived from Medicinal Mushroom Ganoderma lucidum against Mango Anthracnose Pathogen Colletotrichum gloeosporioides (Penz and (Sacc.)).
Muniyappan G, Gurudevan T, Thangaraj P, Balamurali AS, Iyadurai AP, Suppaiah R, Subbiah KA, Shanmugam H. Muniyappan G, et al. Molecules. 2023 Mar 8;28(6):2476. doi: 10.3390/molecules28062476. Molecules. 2023. PMID: 36985447 Free PMC article.
The present investigation is focused on exploring the possibilities of identifying biomolecules from the fruiting body of the medicinal mushroom Ganoderma lucidum against the mango anthracnose pathogen Colletotrichum gloeosporioides. ...Similarly, the analysis of et …
The present investigation is focused on exploring the possibilities of identifying biomolecules from the fruiting body of the medicinal …
Cordycepin ameliorates autoimmunity by promoting STING degradation via autophagy pathway.
Yang D, Peng N, Zhang H, Qiu Z, Xu L, Pan M. Yang D, et al. Br J Pharmacol. 2025 Apr;182(7):1546-1560. doi: 10.1111/bph.17425. Epub 2024 Dec 15. Br J Pharmacol. 2025. PMID: 39675775 Free article.
After treatment with cordycepin, a nucleoside from Cordyceps mushrooms, type I IFNs production and response were determined by western blotting, real-time polymerase chain reaction (PCR), dual-luciferase assay, enzyme-linked immunosorbent assay (ELISA), haematoxylin-eosin …
After treatment with cordycepin, a nucleoside from Cordyceps mushrooms, type I IFNs production and response were determined by wester …
Review of Bioactive Molecules Production, Biomass, and Basidiomata of Shiitake Culinary-Medicinal Mushrooms, Lentinus edodes (Agaricomycetes).
Gaitán-Hernández R, López-Peña D, Esqueda M, Gutiérrez A. Gaitán-Hernández R, et al. Int J Med Mushrooms. 2019;21(9):841-850. doi: 10.1615/IntJMedMushrooms.2019031849. Int J Med Mushrooms. 2019. PMID: 32450024 Review.
Extracts and pure compounds of shiitake exhibit antibacterial, antifungal, cytostatic, antioxidant, anticancer, and immunomodulatory activity. Because of these attributes, different products derived from shiitake are on the market and are sold as dietary supplements. ...In …
Extracts and pure compounds of shiitake exhibit antibacterial, antifungal, cytostatic, antioxidant, anticancer, and immunomodulatory …
Discovery of New Antimicrobial Metabolites in the Coculture of Medicinal Mushrooms.
Ji L, Tan L, Shang Z, Li W, Mo X, Yang S, Yu G. Ji L, et al. J Agric Food Chem. 2024 Mar 13;72(10):5247-5257. doi: 10.1021/acs.jafc.3c09476. Epub 2024 Feb 29. J Agric Food Chem. 2024. PMID: 38425052
Bioactivity screening revealed that the antifungal activities of EtOAc extracts from coculture broths of Trametes versicolor SY630 with either Vanderbylia robiniophila SY341 or Ganoderma gibbosum SY1001 were significantly improved compared to that of monocultures. ...Compo …
Bioactivity screening revealed that the antifungal activities of EtOAc extracts from coculture broths of Trametes versicolor SY630 wi …
Innate immunity induced by fungal β-glucans via dectin-1 signaling pathway.
Lee DH, Kim HW. Lee DH, et al. Int J Med Mushrooms. 2014;16(1):1-16. doi: 10.1615/intjmedmushr.v16.i1.10. Int J Med Mushrooms. 2014. PMID: 24940900 Review.
Mushrooms are a highly valuable source of substances that possess unique biological properties and medicinal efficacy. ...Medicinal mushrooms produce high-molecular-weight beta-glucans, which have antitumor and antifungal activities that stimula …
Mushrooms are a highly valuable source of substances that possess unique biological properties and medicinal efficacy. ...M …
Research Trends in the Study of Edible Mushrooms: Nutritional Properties and Health Benefits.
Sganzerla WG, Todorov SD, da Silva APG. Sganzerla WG, et al. Int J Med Mushrooms. 2022;24(5):1-18. doi: 10.1615/IntJMedMushrooms.2022043738. Int J Med Mushrooms. 2022. PMID: 35695585 Review.
This review summarizes trends in the biotechnological and medicinal potential of edible mushrooms cultivated worldwide. Macronutrients (fatty acids, amino acids, and carbohydrates), bioactive compounds (phenolics, flavonoids, and carotenoids), and health benefits (a …
This review summarizes trends in the biotechnological and medicinal potential of edible mushrooms cultivated worldwide. Macron …
Are chemical compounds in medical mushrooms potent against colorectal cancer carcinogenesis and antimicrobial growth?
Macharia JM, Zhang L, Mwangi RW, Rozmann N, Kaposztas Z, Varjas T, Sugár M, Alfatafta H, Pintér M, Bence RL. Macharia JM, et al. Cancer Cell Int. 2022 Dec 1;22(1):379. doi: 10.1186/s12935-022-02798-2. Cancer Cell Int. 2022. PMID: 36457023 Free PMC article. Review.
Titles and abstracts that matched the established criteria were selected for full-text article scrutiny and subsequently used in the updated present review. Bioactive compounds present in medicinal mushrooms such as ascorbic acid, organic acids, flavonoids, polysacc …
Titles and abstracts that matched the established criteria were selected for full-text article scrutiny and subsequently used in the updated …
Atopic cough and fungal allergy.
Ogawa H, Fujimura M, Ohkura N, Makimura K. Ogawa H, et al. J Thorac Dis. 2014 Oct;6(Suppl 7):S689-98. doi: 10.3978/j.issn.2072-1439.2014.09.25. J Thorac Dis. 2014. PMID: 25383202 Free PMC article. Review.
Fungus-associated chronic cough (FACC) is defined as chronic cough associated with basidiomycetous (BM) fungi found in induced sputum, and recognition of FACC has provided the possibility of using antifungal drugs as new treatment strategies. Bjerkandera adusta is a wood d …
Fungus-associated chronic cough (FACC) is defined as chronic cough associated with basidiomycetous (BM) fungi found in induced sputum, and r …
The role of culinary-medicinal mushrooms on human welfare with a pyramid model for human health.
Chang ST, Wasser SP. Chang ST, et al. Int J Med Mushrooms. 2012;14(2):95-134. doi: 10.1615/intjmedmushr.v14.i2.10. Int J Med Mushrooms. 2012. PMID: 22506573
This review presents a pyramid model for mushroom uses (industries), as food, dietary supplements (tonic), and medicine. A regular intake of mushrooms can make us healthier, fitter, and happier, and help us live longer. ...A total of 126 medicinal func …
This review presents a pyramid model for mushroom uses (industries), as food, dietary supplements (tonic), and medicine. A reg …
Cordymin, an antifungal peptide from the medicinal fungus Cordyceps militaris.
Wong JH, Ng TB, Wang H, Sze SC, Zhang KY, Li Q, Lu X. Wong JH, et al. Phytomedicine. 2011 Mar 15;18(5):387-92. doi: 10.1016/j.phymed.2010.07.010. Epub 2010 Aug 23. Phytomedicine. 2011. PMID: 20739167
Cordymin, an antifungal peptide with a molecular mass of 10,906 Da and an N-terminal amino acid sequence distinct from those of previously reported proteins, was purified from the medicinal mushroom Cordyceps militaris. ...However, there was no effect on Aspe …
Cordymin, an antifungal peptide with a molecular mass of 10,906 Da and an N-terminal amino acid sequence distinct from those of previ …
The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents.
Yap HY, Ariffeen Rosli MF, Tan SH, Kong BH, Fung SY. Yap HY, et al. Mycobiology. 2023 Jan 23;51(1):1-15. doi: 10.1080/12298093.2022.2164641. eCollection 2023. Mycobiology. 2023. PMID: 36846625 Free PMC article. Review.
The presence of bioactive compounds in medicinal mushrooms contributes to various biological activities which assist in the early inflammatory phase, keratinocyte proliferation, and its migration enhancement which are pertinent to wound rehabilitation. Lignosus rhin …
The presence of bioactive compounds in medicinal mushrooms contributes to various biological activities which assist in the ea …
Natural Compounds of Fungal Origin with Antimicrobial Activity-Potential Cosmetics Applications.
Sułkowska-Ziaja K, Trepa M, Olechowska-Jarząb A, Nowak P, Ziaja M, Kała K, Muszyńska B. Sułkowska-Ziaja K, et al. Pharmaceuticals (Basel). 2023 Aug 23;16(9):1200. doi: 10.3390/ph16091200. Pharmaceuticals (Basel). 2023. PMID: 37765008 Free PMC article. Review.
The article describes both individual isolated compounds and extracts that exhibit antibacterial, antifungal, and antiviral activity. These compounds are produced by the fruiting bodies and mycelium, as well as the biomass of mycelial cultures. Additionally, this review ch …
The article describes both individual isolated compounds and extracts that exhibit antibacterial, antifungal, and antiviral activity. …
Terpene Synthases in the Biosynthesis of Drimane-Type Sesquiterpenes across Diverse Organisms.
Chen TH, Lin HC. Chen TH, et al. Chembiochem. 2023 Nov 16;24(22):e202300518. doi: 10.1002/cbic.202300518. Epub 2023 Sep 13. Chembiochem. 2023. PMID: 37605310
Some DTSs contribute to the pungent flavor found in herb plants like water pepper, while others serve as active components responsible for the anti-cancer activities observed in medicinal mushrooms such as (-)-antrocin from Antrodia cinnamomea. Recently, DTS synthas …
Some DTSs contribute to the pungent flavor found in herb plants like water pepper, while others serve as active components responsible for t …
Lentinus crinitus: Traditional use, phytochemical and pharmacological activities, and industrial and biotechnological applications.
Filho JRDS, Santos ÉDS, Linde GA, Colauto NB, Gonçalves RAC, de Oliveira AJB. Filho JRDS, et al. Food Res Int. 2023 Oct;172:113179. doi: 10.1016/j.foodres.2023.113179. Epub 2023 Jun 20. Food Res Int. 2023. PMID: 37689932 Free article. Review.
L. crinitus produces edible fruiting bodies with medicinal, nutritional, and biotechnological applications. The compounds from fungal fruiting bodies can be applied to the preparation of products in the food, cosmetic, biomedical, and pharmaceutical industries. ...Extracts …
L. crinitus produces edible fruiting bodies with medicinal, nutritional, and biotechnological applications. The compounds from fungal …
Ganodermin, an antifungal protein from fruiting bodies of the medicinal mushroom Ganoderma lucidum.
Wang H, Ng TB. Wang H, et al. Peptides. 2006 Jan;27(1):27-30. doi: 10.1016/j.peptides.2005.06.009. Epub 2005 Jul 21. Peptides. 2006. PMID: 16039755
A 15-kDa antifungal protein, designated ganodermin, was isolated from the medical mushroom Ganoderma lucidum. ...
A 15-kDa antifungal protein, designated ganodermin, was isolated from the medical mushroom Ganoderma lucidum. ...
beta-(1 3),(1 6)-Glucans: medicinal activities, characterization, biosynthesis and new horizons.
Dalonso N, Goldman GH, Gern RM. Dalonso N, et al. Appl Microbiol Biotechnol. 2015 Oct;99(19):7893-906. doi: 10.1007/s00253-015-6849-x. Epub 2015 Aug 8. Appl Microbiol Biotechnol. 2015. PMID: 26252967 Review.
Biological activities of medicinal mushrooms have been attributed to beta-(1 3),(1 6)-glucans that are present in the cell wall of fungi and some plants. ...Due to the biological importance of beta-(1 3),(1 6)-glucan, it is necessary to understand the biochemical an …
Biological activities of medicinal mushrooms have been attributed to beta-(1 3),(1 6)-glucans that are present in the cell wal …
The Hidden Fortress: A Comprehensive Review of Fungal Biofilms with Emphasis on Cryptococcus neoformans.
Pruitt HM, Zhu JC, Riley SP, Shi M. Pruitt HM, et al. J Fungi (Basel). 2025 Mar 19;11(3):236. doi: 10.3390/jof11030236. J Fungi (Basel). 2025. PMID: 40137272 Free PMC article. Review.
These surprisingly common biofilms are morphologically distinct from the multicellular molds and mushrooms normally associated with fungi and are instead an assemblage of single-celled organisms. ...Notably, biofilm association correlates with increased expression of multi …
These surprisingly common biofilms are morphologically distinct from the multicellular molds and mushrooms normally associated with f …
A review on the nucleic acid constituents in mushrooms: nucleobases, nucleosides and nucleotides.
Phan CW, Wang JK, Cheah SC, Naidu M, David P, Sabaratnam V. Phan CW, et al. Crit Rev Biotechnol. 2018 Aug;38(5):762-777. doi: 10.1080/07388551.2017.1399102. Epub 2017 Nov 10. Crit Rev Biotechnol. 2018. PMID: 29124970 Review.
Mushrooms have become increasingly important as a reliable food source. They have also been recognized as an important source of bioactive compounds of high nutritional and medicinal values. ...Cordycepin, a 3'-deoxyadenosine found in Cordyceps sinensis has received …
Mushrooms have become increasingly important as a reliable food source. They have also been recognized as an important source of bioa …
Fungal proteinaceous compounds with multiple biological activities.
Ng TB, Cheung RCF, Wong JH, Chan YS, Dan X, Pan W, Wang H, Guan S, Chan K, Ye X, Liu F, Xia L, Chan WY. Ng TB, et al. Appl Microbiol Biotechnol. 2016 Aug;100(15):6601-6617. doi: 10.1007/s00253-016-7671-9. Epub 2016 Jun 23. Appl Microbiol Biotechnol. 2016. PMID: 27338574 Review.
Fungi comprise organisms like molds, yeasts and mushrooms. They have been used as food or medicine for a long time. A large number of fungal proteins or peptides with diverse biological activities are considered as antibacterial, antifungal, antiviral and ant …
Fungi comprise organisms like molds, yeasts and mushrooms. They have been used as food or medicine for a long time. A large nu …
A Review: The Bioactivities and Pharmacological Applications of Phellinus linteus.
Chen W, Tan H, Liu Q, Zheng X, Zhang H, Liu Y, Xu L. Chen W, et al. Molecules. 2019 May 16;24(10):1888. doi: 10.3390/molecules24101888. Molecules. 2019. PMID: 31100959 Free PMC article. Review.
Phellinus linteus is a popular medicinal mushroom that is widely used in China, Korea, Japan, and other Asian countries. P. linteus comprises various bioactive components, such as polysaccharides, triterpenoids, phenylpropanoids, and furans, and has proven to be an …
Phellinus linteus is a popular medicinal mushroom that is widely used in China, Korea, Japan, and other Asian countries. P. li …
Immunomodulatory activity of Pleurotus pulmonarius crude extract to human monocyte against Cryptococcus neoformans.
Arromsava A, Chuchawankul S, Worasilchai N, Angkasekwinai P, Amornsupak K. Arromsava A, et al. BMC Complement Med Ther. 2025 Jul 9;25(1):251. doi: 10.1186/s12906-025-04990-z. BMC Complement Med Ther. 2025. PMID: 40634971 Free PMC article.
Pleurotus pulmonarius (PP) is an edible mushroom rich in bioactive molecules, particularly beta-glucan. This study aimed to investigate the immunomodulatory activities of PP crude extract on monocytes and macrophages against C. neoformans. ...Immune mechanisms related to C …
Pleurotus pulmonarius (PP) is an edible mushroom rich in bioactive molecules, particularly beta-glucan. This study aimed to investiga …
Polysaccharides and Peptides With Wound Healing Activity From Bacteria and Fungi.
Arslan NP, Orak T, Ozdemir A, Altun R, Esim N, Eroglu E, Karaagac SI, Aktas C, Taskin M. Arslan NP, et al. J Basic Microbiol. 2024 Dec;64(12):e2400510. doi: 10.1002/jobm.202400510. Epub 2024 Oct 16. J Basic Microbiol. 2024. PMID: 39410821 Free PMC article. Review.
Bacteria and fungi are natural sources of metabolites exhibiting diverse bioactive properties such as wound healing, antioxidative, antibacterial, antifungal, anti-inflammatory, antidiabetic, and anticancer activities. Two important groups of bacteria or fungi-derived meta …
Bacteria and fungi are natural sources of metabolites exhibiting diverse bioactive properties such as wound healing, antioxidative, antibact …
Recognizing filamentous basidiomycetes as agents of human disease: A review.
Chowdhary A, Kathuria S, Agarwal K, Meis JF. Chowdhary A, et al. Med Mycol. 2014 Nov;52(8):782-97. doi: 10.1093/mmy/myu047. Epub 2014 Sep 8. Med Mycol. 2014. PMID: 25202126 Review.
These fungi are present in the environment as gilled mushrooms, shelf fungi, and bracket fungi. However, in clinical settings, they usually present as nonsporulating white moulds that are difficult to identify. ...
These fungi are present in the environment as gilled mushrooms, shelf fungi, and bracket fungi. However, in clinical settings, they u …
Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview.
Cör Andrejč D, Knez Ž, Knez Marevci M. Cör Andrejč D, et al. Front Pharmacol. 2022 Jul 22;13:934982. doi: 10.3389/fphar.2022.934982. eCollection 2022. Front Pharmacol. 2022. PMID: 35935849 Free PMC article. Review.
Ganoderma lucidum is a very medicinal mushroom that has been utilized in Oriental medicine for many years. It has a wide range of pharmacological and therapeutic properties, and has been used for many years as a health promoter. It contains various biological …
Ganoderma lucidum is a very medicinal mushroom that has been utilized in Oriental medicine for many years. It has a wid …
The two faces of Coprinus comatus-Functional properties and potential hazards.
Nowakowski P, Naliwajko SK, Markiewicz-Żukowska R, Borawska MH, Socha K. Nowakowski P, et al. Phytother Res. 2020 Nov;34(11):2932-2944. doi: 10.1002/ptr.6741. Epub 2020 May 27. Phytother Res. 2020. PMID: 32462723 Free PMC article. Review.
Mushrooms have been used for centuries not only as food but also in traditional medicine as a source of components with pro-health activity. ...Pers. also called shaggy mane, chicken drumstick mushroom, or lawyer's wig. In Asian countries, C. comatus (CC) is …
Mushrooms have been used for centuries not only as food but also in traditional medicine as a source of components with pro-he …
Schizophyllum commune-induced Pulmonary Mycosis.
Shen Q, Yao YK, Yang Q, Zhou JY. Shen Q, et al. Chin Med J (Engl). 2016 Sep 5;129(17):2141-2. doi: 10.4103/0366-6999.189062. Chin Med J (Engl). 2016. PMID: 27569249 Free PMC article. No abstract available.
Recent Advances in the Discovery of Antiviral Metabolites from Fungi.
Deshmukh SK, Agrawal S, Gupta MK, Patidar RK, Ranjan N. Deshmukh SK, et al. Curr Pharm Biotechnol. 2022;23(4):495-537. doi: 10.2174/1389201022666210615120720. Curr Pharm Biotechnol. 2022. PMID: 34132180 Review.
As the world manages the impact of a global pandemic caused by COVID-19, the discovery of new antiviral agents has become way more relevant and urgent. Viruses are submicroscopic infectious agents that replicate inside the living cells of different organisms. ...Fun …
As the world manages the impact of a global pandemic caused by COVID-19, the discovery of new antiviral agents has become way more re …
In vitro and in vivo biological activities of azulene derivatives with potential applications in medicine.
Bakun P, Czarczynska-Goslinska B, Goslinski T, Lijewski S. Bakun P, et al. Med Chem Res. 2021;30(4):834-846. doi: 10.1007/s00044-021-02701-0. Epub 2021 Jan 30. Med Chem Res. 2021. PMID: 33551629 Free PMC article. Review.
Azulene derivatives, including guaiazulene or chamazulene, occur in nature as components of many plants and mushrooms, such as Matricaria chamomilla, Artemisia absinthium, Achillea millefolium, and Lactarius indigo. ...The potential use of these compounds concerns various …
Azulene derivatives, including guaiazulene or chamazulene, occur in nature as components of many plants and mushrooms, such as Matric …
Antimicrobial Activities of Ganoderma mbrekobenum Strain EGDA (Agaricomycetes) from Egypt.
El-Dein MMN, El-Fallal AA, El-Sayed AKA, El-Esseily SR. El-Dein MMN, et al. Int J Med Mushrooms. 2023;25(9):31-41. doi: 10.1615/IntJMedMushrooms.2023049502. Int J Med Mushrooms. 2023. PMID: 37824404
Ganoderma is a well-known genus of medicinal mushrooms. The biological activity of the fruiting bodies of G. mbrekobenum (previously identified as Ganoderma sp. ...Water fraction showed antibacterial effect against most of the test bacterial strains. The highest …
Ganoderma is a well-known genus of medicinal mushrooms. The biological activity of the fruiting bodies of G. mbrekobenum (prev …
Cordycepin in Anticancer Research: Molecular Mechanism of Therapeutic Effects.
Khan MA, Tania M. Khan MA, et al. Curr Med Chem. 2020;27(6):983-996. doi: 10.2174/0929867325666181001105749. Curr Med Chem. 2020. PMID: 30277143 Review.
BACKGROUND: Cordycepin is a nucleotide analogue from Cordyceps mushrooms, which occupies a notable place in traditional medicine. OBJECTIVE: In this review article, we have discussed the recent findings on the molecular aspects of cordycepin interactions with its re …
BACKGROUND: Cordycepin is a nucleotide analogue from Cordyceps mushrooms, which occupies a notable place in traditional medicine …
Insights into the methods for separation and chromatographic determination of nucleotides/nucleosides in Cordyceps spp.
Peng T, Li X, Tong X. Peng T, et al. J Chromatogr A. 2024 Oct 11;1734:465279. doi: 10.1016/j.chroma.2024.465279. Epub 2024 Aug 24. J Chromatogr A. 2024. PMID: 39197362 Review.
Cordyceps genus is entomopathogenic mushrooms that have traditionally been used in ethnomedicine in Asian countries. Nucleosides (Ns), nucleotide(Nt), Nucleobases (Nb) and their analogues play a critically physiological role and have a great potential in drug development, …
Cordyceps genus is entomopathogenic mushrooms that have traditionally been used in ethnomedicine in Asian countries. Nucleosides (Ns) …
Medicinal Properties of the Genus Clitocybe and of Lectins from the Clouded Funnel Cap Mushroom, C. nebularis (Agaricomycetes): A Review.
Pohleven J, Kos J, Sabotic J. Pohleven J, et al. Int J Med Mushrooms. 2016;18(11):965-975. doi: 10.1615/IntJMedMushrooms.v18.i11.20. Int J Med Mushrooms. 2016. PMID: 28008809 Review.
Species of the genus Clitocybe, including C. nebularis, have not been traditionally considered as medicinal mushrooms; however, recent studies have demonstrated their antitumor, immunomodulatory, and antioxidative properties, their antimicrobial (antiviral, antibact …
Species of the genus Clitocybe, including C. nebularis, have not been traditionally considered as medicinal mushrooms; however …
Review on Research Progress and Prospects of Cicada Flower, Isaria cicadae (Ascomycetes).
Li CR, Wang YQ, Cheng WM, Chen ZA, Hywel-Jones N, Li ZZ. Li CR, et al. Int J Med Mushrooms. 2021;23(4):81-91. doi: 10.1615/IntJMedMushrooms.2021038085. Int J Med Mushrooms. 2021. PMID: 33822510 Review.
Cicada flower, Isaria cicadae Miq., has been a traditional Chinese medicine for approximately 1600 years. Many works on its identification, bioactivities, and clinical use against some disorders have been published, but some inaccuracies and inconsistencies need to be furt …
Cicada flower, Isaria cicadae Miq., has been a traditional Chinese medicine for approximately 1600 years. Many works on its identific …
Ganoderma lucidum-Mediated Green Synthesis of Silver Nanoparticles with Antimicrobial Activity.
Constantin M, Răut I, Suica-Bunghez R, Firinca C, Radu N, Gurban AM, Preda S, Alexandrescu E, Doni M, Jecu L. Constantin M, et al. Materials (Basel). 2023 Jun 8;16(12):4261. doi: 10.3390/ma16124261. Materials (Basel). 2023. PMID: 37374445 Free PMC article.
Nanoparticles can be synthesized by algae, bacteria, fungi, and plant extracts. Ganoderma lucidum is a commonly used medicinal mushroom with distinctive biological properties, such as antibacterial, antifungal, antioxidant, anti-inflammatory, anticancer, etc. …
Nanoparticles can be synthesized by algae, bacteria, fungi, and plant extracts. Ganoderma lucidum is a commonly used medicinal mus …
Diversity of Polypore Bracket Mushrooms, Polyporales (Agaricomycetes), Recorded in Armenia and Their Medicinal Properties.
Badalyan SM, Gharibyan NG. Badalyan SM, et al. Int J Med Mushrooms. 2016;18(4):347-54. doi: 10.1615/IntJMedMushrooms.v18.i4.80. Int J Med Mushrooms. 2016. PMID: 27481301
The list of polypore bracket mushrooms (Polyporales) recorded in Armenia is presented. The order Polyporales in Armenia is currently represented by 87 species (4 varieties) belonging to 47 genera. Information regarding the study of the medicinal properties (e.g., …
The list of polypore bracket mushrooms (Polyporales) recorded in Armenia is presented. The order Polyporales in Armenia is currently …
Narrative Review: Bioactive Potential of Various Mushrooms as the Treasure of Versatile Therapeutic Natural Product.
Chopra H, Mishra AK, Baig AA, Mohanta TK, Mohanta YK, Baek KH. Chopra H, et al. J Fungi (Basel). 2021 Sep 6;7(9):728. doi: 10.3390/jof7090728. J Fungi (Basel). 2021. PMID: 34575766 Free PMC article. Review.
Mushrooms have remained an eternal part of traditional cuisines due to their beneficial health potential and have long been recognized as a folk medicine for their broad spectrum of nutraceuticals, as well as therapeutic and prophylactic uses. ...This article highli …
Mushrooms have remained an eternal part of traditional cuisines due to their beneficial health potential and have long been recognize …
An antifungal protein from the culinary-medicinal beech mushroom, Hypsizygus marmoreus (Peck) Bigel. (Agaricomycetideae).
Suzuki T, Umehara K, Tashiro A, Kobayashi Y, Dohra H, Hirai H, Kawagishi H. Suzuki T, et al. Int J Med Mushrooms. 2011;13(1):27-31. doi: 10.1615/intjmedmushr.v13.i1.40. Int J Med Mushrooms. 2011. PMID: 22135901
An antifungal protein (HM-af) was purified from the culinary-medicinal mushroom Hypsizygus marmoreus. ...The N-terminal amino acid sequence of HM-af showed homology to ribonuclease H from Clostridium thermocellum. HM-af showed the antifungal activity a …
An antifungal protein (HM-af) was purified from the culinary-medicinal mushroom Hypsizygus marmoreus. ...The N-terminal …
Biological Synthesis, Characterization, and Therapeutic Potential of S. commune-Mediated Gold Nanoparticles.
Alqurashi YE, Almalki SG, Ibrahim IM, Mohammed AO, Abd El Hady AE, Kamal M, Fatima F, Iqbal D. Alqurashi YE, et al. Biomolecules. 2023 Dec 13;13(12):1785. doi: 10.3390/biom13121785. Biomolecules. 2023. PMID: 38136655 Free PMC article.
Furthermore, the efficiency of the AuNPs' antifungal and cytotoxic properties, as well as their production of intracellular ROS, was evaluated. ...Therefore, these metallic AuNPs produced by fungus (S. commune) can be used as an effective antifungal, anticancer, and …
Furthermore, the efficiency of the AuNPs' antifungal and cytotoxic properties, as well as their production of intracellular ROS, was …
Sesquiterpenes from an Eastern African Medicinal Mushroom Belonging to the Genus Sanghuangporus.
Cheng T, Chepkirui C, Decock C, Matasyoh JC, Stadler M. Cheng T, et al. J Nat Prod. 2019 May 24;82(5):1283-1291. doi: 10.1021/acs.jnatprod.8b01086. Epub 2019 Apr 19. J Nat Prod. 2019. PMID: 31001977
The producing organism represents a new species of the genus Sanghuangporus, which is one of the segregates of the important traditional Asian medicinal mushrooms that were formerly known as the " Inonotus linteus" complex. The structure elucidation of compounds 1-1 …
The producing organism represents a new species of the genus Sanghuangporus, which is one of the segregates of the important traditional Asi …
In vitro and in vivo inhibitory effects of the Sanghuang mushroom extracts against Candida albicans.
Du J, Jin S, Zhang Y, Qiu W, Dong Y, Liu Y, Yin D, Yang Y, Xu W. Du J, et al. Future Microbiol. 2024;19(11):983-996. doi: 10.1080/17460913.2024.2352269. Epub 2024 Jun 21. Future Microbiol. 2024. PMID: 38904292 Free PMC article.
Aim: To explore the antifungal potential of Sanghuang mushroom, a traditional Chinese medicine. Materials & methods: The antifungal properties and the potential mechanism of Sanghuang mushroom extracts against Candida albicans were studied i …
Aim: To explore the antifungal potential of Sanghuang mushroom, a traditional Chinese medicine. Materials & methods …
Traditional Uses, Bioactive Compounds, and New Findings on Pharmacological, Nutritional, Cosmetic and Biotechnology Utility of Capsella bursa-pastoris.
Łukaszyk A, Kwiecień I, Szopa A. Łukaszyk A, et al. Nutrients. 2024 Dec 20;16(24):4390. doi: 10.3390/nu16244390. Nutrients. 2024. PMID: 39771011 Free PMC article. Review.
Capsella bursa-pastoris (L.) Medik. (shepherd's purse) is a medicinal plant recently introduced to European Pharmacopoeia. The main active compounds responsible for the activity profile of the raw material are flavonoids, phenolic acids, amino acids, phytosterols, vitamins …
Capsella bursa-pastoris (L.) Medik. (shepherd's purse) is a medicinal plant recently introduced to European Pharmacopoeia. The main a …
Medicinal Potential of the Insoluble Extracted Fibers Isolated from the Fomes fomentarius (Agaricomycetes) Fruiting Bodies: A Review.
Kalitukha L, Galiano A, Harrison F. Kalitukha L, et al. Int J Med Mushrooms. 2023;25(3):21-35. doi: 10.1615/IntJMedMushrooms.2022047222. Int J Med Mushrooms. 2023. PMID: 37017659 Review.
Since then, a number of research papers and reviews have mentioned the history of use, taxonomy, composition and medicinal properties of some F. fomentarius preparations, e.g., soluble extracts and their fractions, isolated cell walls, mycelia and compounds purified from t …
Since then, a number of research papers and reviews have mentioned the history of use, taxonomy, composition and medicinal properties …
Highly potent anti-melanogenic effect of 2-thiobenzothiazole derivatives through nanomolar tyrosinase activity inhibition.
Jin Jung H, Jin Kim H, Soo Park H, Young Kim G, Jung Park Y, Lee J, Kyung Kang M, Yoon D, Kang D, Park Y, Chun P, Young Chung H, Ryong Moon H. Jin Jung H, et al. Bioorg Chem. 2024 Sep;150:107586. doi: 10.1016/j.bioorg.2024.107586. Epub 2024 Jun 22. Bioorg Chem. 2024. PMID: 38955001
Eight of the ten 2-TBT derivatives inhibited the monophenolase and diphenolase activities of mushroom tyrosinase, with IC(50) values of 0.02-0.83 muM. Kinetic studies and molecular dynamics simulations were performed to determine their mode of action and confirm that the 2 …
Eight of the ten 2-TBT derivatives inhibited the monophenolase and diphenolase activities of mushroom tyrosinase, with IC(50) values …
Edible mushrooms as meat analogues: A comprehensive review of nutritional, therapeutic, and market potential.
Boro S, Kambhampati V, Das S, Saikia D. Boro S, et al. Food Res Int. 2025 Aug;214:116632. doi: 10.1016/j.foodres.2025.116632. Epub 2025 May 15. Food Res Int. 2025. PMID: 40467220 Review.
In addition, mushrooms are the only vegetative source of vitamin D and are recognised for their therapeutic potential, attributed to a range of medicinal properties like anti-tumour, antioxidant, immunomodulatory, anti-microbial, anti-inflammatory, cardiovascular-pr …
In addition, mushrooms are the only vegetative source of vitamin D and are recognised for their therapeutic potential, attributed to …
Black Trumpet [Craterellus cornucopioides (L.) Pers.]-Bioactive Properties and Prospects for Application in Medicine and Production of Health-Promoting Food.
Adamska I, Felisiak K. Adamska I, et al. Nutrients. 2024 Apr 28;16(9):1325. doi: 10.3390/nu16091325. Nutrients. 2024. PMID: 38732570 Free PMC article. Review.
Black trumpet (Craterellus cornucopioides) is a mushroom present in many countries but underestimated. The aim of this publication is to present the latest state of knowledge about the chemical composition and bioactivity of C. cornucopioides and the possibility of its app …
Black trumpet (Craterellus cornucopioides) is a mushroom present in many countries but underestimated. The aim of this publication is …
Isolation and Identification of Chemical Compounds from Agaricus blazei Murrill and Their In Vitro Antifungal Activities.
Yu R, Li X, Yi P, Wen P, Wang S, Liao C, Song X, Wu H, He Z, Li C. Yu R, et al. Molecules. 2023 Oct 28;28(21):7321. doi: 10.3390/molecules28217321. Molecules. 2023. PMID: 37959740 Free PMC article.
This study explores the antifungal properties of Agaricus blazei Murrill, a valuable medicinal and edible fungus. ...The results demonstrate varied sensitivities against these pathogenic fungi, with compound 2 showing significant inhibition against T. mentagropholog …
This study explores the antifungal properties of Agaricus blazei Murrill, a valuable medicinal and edible fungus. ...The resul …
An Immunomodulatory Mushroom, Cordyceps militaris, and Its Constituents: A Review of In Vitro/In Vivo Studies and Clinical Trials.
Yang EJ, Jin L, Jiang HH, Lee BG, Han EH, Yun CH, Na DH. Yang EJ, et al. Phytother Res. 2026 Feb;40(2):635-665. doi: 10.1002/ptr.70144. Epub 2025 Dec 23. Phytother Res. 2026. PMID: 41432716 Review.
Cordyceps, known as "winter-worm summer-grass", has been used as a medicinal mushroom to boost energy levels and immune activity. Among cordyceps types, Cordyceps militaris (CM) is the most commercially useful owing to its ease of artificial cultivation for mass pro …
Cordyceps, known as "winter-worm summer-grass", has been used as a medicinal mushroom to boost energy levels and immune activi …
Nutritional, Nutraceutical, and Medicinal Potential of Cantharellus cibarius Fr.: A Comprehensive Review.
Kumar A, Devi R, Dhalaria R, Tapwal A, Verma R, Rashid S, Elossaily GM, Khan KA, Chen KT, Verma T. Kumar A, et al. Food Sci Nutr. 2024 Dec 13;13(1):e4641. doi: 10.1002/fsn3.4641. eCollection 2025 Jan. Food Sci Nutr. 2024. PMID: 39803245 Free PMC article. Review.
Mushrooms are considered as nutraceutical foods that can effectively prevent diseases such as cancer and other serious life-threatening conditions include neurodegeneration, hypertension, diabetes, and hypercholesterolemia. ...Furthermore, there is a need to valorize waste …
Mushrooms are considered as nutraceutical foods that can effectively prevent diseases such as cancer and other serious life-threateni …
Breakthrough Invasive Sinusitis by Hormographiella aspergillata in a Neutropenic Patient Receiving Voriconazole Therapy: A Case Report and Review of Breakthrough H. aspergillata Infections.
Florez-Riaño AF, Ramírez-Sánchez IC. Florez-Riaño AF, et al. Mycopathologia. 2023 Aug;188(4):401-407. doi: 10.1007/s11046-023-00768-4. Epub 2023 Jun 30. Mycopathologia. 2023. PMID: 37389746 Review.
Breakthrough invasive infections occurs during the use of antifungals both in prophylaxis and therapy, it favors the emergence of new pathogens in the fungal landscape. Hormographiella aspergillata is considered a rare but emerging pathogen in the era of broad-spectrum …
Breakthrough invasive infections occurs during the use of antifungals both in prophylaxis and therapy, it favors the emergence of new …
Recent developments in toxic nephropathy.
Wali RK, Henrich WL. Wali RK, et al. Curr Opin Nephrol Hypertens. 2002 Mar;11(2):155-63. doi: 10.1097/00041552-200203000-00005. Curr Opin Nephrol Hypertens. 2002. PMID: 11856907 Review.
Extrapolating Qualitative Mycochemical Profiling and Therapeutic Potential of Two Mycorrhizal Amanita Species (Agaricomycetes) from Pakistan.
Shafique M, Niazi AR, Imran M, Zaheer M. Shafique M, et al. Int J Med Mushrooms. 2023;25(4):55-63. doi: 10.1615/IntJMedMushrooms.2023047505. Int J Med Mushrooms. 2023. PMID: 37075084
Different concentrations of ethanolic extracts of both mushrooms were subjected to anthelmintic potential against parasite Haemonchus contortus. ...From the results obtained it was concluded that both mushrooms can be used as potential source of curative antibacteri …
Different concentrations of ethanolic extracts of both mushrooms were subjected to anthelmintic potential against parasite Haemonchus …
Bioactivity and Metabolomic Profile of Extracts Derived from Mycelial Solid Cultures of Hypsizygus marmoreus.
Angelini P, Flores GA, Cusumano G, Venanzoni R, Pellegrino RM, Zengin G, Di Simone SC, Menghini L, Ferrante C. Angelini P, et al. Microorganisms. 2023 Oct 13;11(10):2552. doi: 10.3390/microorganisms11102552. Microorganisms. 2023. PMID: 37894210 Free PMC article.
The beech mushroom (Hypsizygus marmoreus) is a highly nutritious, edible medicinal mushroom native to East Asia. ...In conclusion, growth substrate selection affects the nutritional and medicinal properties of H. marmoreus, making it a valuable contrib …
The beech mushroom (Hypsizygus marmoreus) is a highly nutritious, edible medicinal mushroom native to East Asia. ...In …
Pananotin, a potent antifungal protein from roots of the traditional chinese medicinal herb Panax notoginseng.
Lam SK, Ng TB. Lam SK, et al. Planta Med. 2002 Nov;68(11):1024-8. doi: 10.1055/s-2002-35649. Planta Med. 2002. PMID: 12451495
The second peak was dialyzed and chromatographed on an FPLC-gel filtration Superdex 75 column. An antifungal protein with an N-terminal sequence similar to those of chitinases was isolated from the first peak which had a molecular mass of 35 kDa. ...It inhibited cell-free …
The second peak was dialyzed and chromatographed on an FPLC-gel filtration Superdex 75 column. An antifungal protein with an N-termin …
Antifungal and Antibacterial Activities of Crude Extracts of Four Phellinus Species and Coltricia fragilissima (Agaricomycetes) from Cameroon and Democratic Republic of Congo.
Metsebing BP, Oba R, Tsigain FT, Fonkui TY, Fotsing MCD, Mungoh TC, Ndinteh DN, Mossebo DC. Metsebing BP, et al. Int J Med Mushrooms. 2024;26(10):9-18. doi: 10.1615/IntJMedMushrooms.2024054634. Int J Med Mushrooms. 2024. PMID: 39171628
Antifungal and antibacterial activities of crude extracts of Phellinus extensus, Ph. gilvus, Ph. pachyphloeus, Ph. senex and Coltricia fragilissima were investigated on eleven species of bacteria and three fungal human pathogens. ...C. fragilissima being of the same family …
Antifungal and antibacterial activities of crude extracts of Phellinus extensus, Ph. gilvus, Ph. pachyphloeus, Ph. senex and Coltrici …
Effects of Sparassis crispa in Medical Therapeutics: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Thi Nhu Ngoc L, Oh YK, Lee YJ, Lee YC. Thi Nhu Ngoc L, et al. Int J Mol Sci. 2018 May 16;19(5):1487. doi: 10.3390/ijms19051487. Int J Mol Sci. 2018. PMID: 29772715 Free PMC article.
The original efficacy treatment of the mushroom extract is considered primarily and searched in electronic databases. A total of 623 articles were assessed, 33 randomized controlled experiments were included after the manual screening, and some papers, review articles, or …
The original efficacy treatment of the mushroom extract is considered primarily and searched in electronic databases. A total of 623 …
Mushroom lectins: current status and future perspectives.
Singh RS, Bhari R, Kaur HP. Singh RS, et al. Crit Rev Biotechnol. 2010 Jun;30(2):99-126. doi: 10.3109/07388550903365048. Crit Rev Biotechnol. 2010. PMID: 20105049 Review.
Numerous novel lectins with unique specificities and exploitable properties have been discovered. Mushrooms have attracted a number of researchers in food and pharmaceuticals. Many species have long been used in traditional Chinese medicines or functional foods in J …
Numerous novel lectins with unique specificities and exploitable properties have been discovered. Mushrooms have attracted a number o …
Fomitopsis officinalis: Spatial (Pileus and Hymenophore) Metabolomic Variations Affect Functional Components and Biological Activities.
Flores GA, Cusumano G, Ianni F, Blasi F, Angelini P, Cossignani L, Pellegrino RM, Emiliani C, Venanzoni R, Zengin G, Acquaviva A, Di Simone SC, Libero ML, Nilofar, Orlando G, Menghini L, Ferrante C. Flores GA, et al. Antibiotics (Basel). 2023 Apr 16;12(4):766. doi: 10.3390/antibiotics12040766. Antibiotics (Basel). 2023. PMID: 37107128 Free PMC article.
Fomitopsis officinalis is a holartic polyporous mushroom that forms large fruiting bodies on old standing trees, fallen logs, or stumps. F. officinalis is a medicinal mushroom species that is most commonly used in traditional European medicine. ...
Fomitopsis officinalis is a holartic polyporous mushroom that forms large fruiting bodies on old standing trees, fallen logs, or stum …
A haemagglutinin from the medicinal fungus Cordyceps militaris.
Wong JH, Wang H, Ng TB. Wong JH, et al. Biosci Rep. 2009 Jun 25;29(5):321-7. doi: 10.1042/BSR20080153. Biosci Rep. 2009. PMID: 19093913
There are only a few reports on agglutinins from ascomycete and medicinal fungi. An HA (haemagglutinin), with an N-terminal amino acid sequence different from those of known lectins, was isolated in the present study from dried fruiting bodies of the medicinal ascom …
There are only a few reports on agglutinins from ascomycete and medicinal fungi. An HA (haemagglutinin), with an N-terminal amino aci …
Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia.
Knežević A, Stajić M, Sofrenić I, Stanojković T, Milovanović I, Tešević V, Vukojević J. Knežević A, et al. PLoS One. 2018 Aug 31;13(8):e0203064. doi: 10.1371/journal.pone.0203064. eCollection 2018. PLoS One. 2018. PMID: 30169542 Free PMC article.
In a last few decades mushrooms are increasingly attracting attention as functional food and sources of biologically active compounds. Several Trametes species have been used for centuries in traditional medicine of East Asia cultures, but only T. versicolor was stu …
In a last few decades mushrooms are increasingly attracting attention as functional food and sources of biologically active compounds …
Discovery of amphotericin B, an antifungal drug as tyrosinase inhibitor with potent anti-melanogenic activity.
Mahalapbutr P, Sabuakham S, Nasoontorn S, Rungrotmongkol T, Silsirivanit A, Suriya U. Mahalapbutr P, et al. Int J Biol Macromol. 2023 Aug 15;246:125587. doi: 10.1016/j.ijbiomac.2023.125587. Epub 2023 Jun 27. Int J Biol Macromol. 2023. PMID: 37379954
Tyrosinase, a rate-limiting enzyme for melanin production, has been the most efficient target for the development of depigmenting agents. Although hydroquinone, kojic acid, and arbutin are the most well-known tyrosinase inhibitors, their adverse effects are inevitable. ... …
Tyrosinase, a rate-limiting enzyme for melanin production, has been the most efficient target for the development of depigmenting agents …
Blood purification for intoxication.
Nakae H. Nakae H. Contrib Nephrol. 2010;166:93-99. doi: 10.1159/000314857. Epub 2010 May 7. Contrib Nephrol. 2010. PMID: 20472996
The causative substances cover a wide range, from medical drugs or agrichemicals to natural poisons (such as poisonous mushrooms). In removing these substances, gastric lavage, activated carbon administration, laxative administration or enema cleaning are the preferred met …
The causative substances cover a wide range, from medical drugs or agrichemicals to natural poisons (such as poisonous mushrooms). In …
Inhibition of cell cycle-dependent hyphal and biofilm formation by a novel cytochalasin 19,20‑epoxycytochalasin Q in Candida albicans.
Watchaputi K, Jayasekara LACB, Ratanakhanokchai K, Soontorngun N. Watchaputi K, et al. Sci Rep. 2023 Jun 15;13(1):9724. doi: 10.1038/s41598-023-36191-4. Sci Rep. 2023. PMID: 37322086 Free PMC article.
Here, we investigated the antihyphal and antibiofilm activity of 19,20-epoxycytochalasin Q (ECQ), a cytochalasin actin inhibitor isolated from medicinal mushroom Xylaria sp. BCC1067 against Candida albicans. Remarkably, 256 g/ml of ECQ inhibited over 95% of C. albi …
Here, we investigated the antihyphal and antibiofilm activity of 19,20-epoxycytochalasin Q (ECQ), a cytochalasin actin inhibitor isolated fr …
Medicinal uses of the mushroom Cordyceps militaris: current state and prospects.
Das SK, Masuda M, Sakurai A, Sakakibara M. Das SK, et al. Fitoterapia. 2010 Dec;81(8):961-8. doi: 10.1016/j.fitote.2010.07.010. Epub 2010 Jul 19. Fitoterapia. 2010. PMID: 20650308 Review.
Besides their popular applications for tonic medicine by the all stairs of the community, the constituents of C. militaris are now used extensively in modern systems of medicine. ...The prospects for herbal biotechnology regarding drug discovery using C. militaris d …
Besides their popular applications for tonic medicine by the all stairs of the community, the constituents of C. militaris are now us …
Cordyceps s.l. (Ascomycetes) Species Used as Medicinal Mushrooms are Closely Related with Higher Ability to Produce Cordycepin.
Kuo HC, Huang IC, Chen TY. Kuo HC, et al. Int J Med Mushrooms. 2015;17(11):1077-85. doi: 10.1615/intjmedmushrooms.v17.i11.80. Int J Med Mushrooms. 2015. PMID: 26853963
(sensu lato) species have been used as herbal medicines; one of their main constituents is cordycepin. As genome sequencing techniques have become more cost-effective and more popular, more entomogenous fungal genomes have been sequenced and published. ...Presence of an RN …
(sensu lato) species have been used as herbal medicines; one of their main constituents is cordycepin. As genome sequencing technique …
Conservation of Endangered Cordyceps sinensis Through Artificial Cultivation Strategies of C. militaris, an Alternate.
Krishna KV, Balasubramanian B, Park S, Bhattacharya S, Kadanthottu Sebastian J, Liu WC, Pappuswamy M, Meyyazhagan A, Kamyab H, Chelliapan S, Malaviya A. Krishna KV, et al. Mol Biotechnol. 2025 Apr;67(4):1382-1397. doi: 10.1007/s12033-024-01154-1. Epub 2024 Apr 24. Mol Biotechnol. 2025. PMID: 38658470 Review.
Cordyceps, an entomopathogenic fungus belonging to the Ascomycota phylum, is a familiar remedial mushroom that is extensively used in the traditional medicinal system, especially in South Asian nations. ...
Cordyceps, an entomopathogenic fungus belonging to the Ascomycota phylum, is a familiar remedial mushroom that is extensively used in …
Antimicrobial Activity of Different Collections of Medicinal Polypore Fungus Fomitopsis pinicola (Agaricomycetes).
Badalyan SM, Shnyreva AV, Barkhudaryan A. Badalyan SM, et al. Int J Med Mushrooms. 2024;26(12):33-48. doi: 10.1615/IntJMedMushrooms.2024055590. Int J Med Mushrooms. 2024. PMID: 39704618
In dual culture experiments, F. pinicola showed high antagonistic/antifungal activity toward test fungi by suppressing their average growth rate (GRavr) and sporulation causing morphological changes of colonies. ...Further studies to elucidate the mechanism of antimicrobia …
In dual culture experiments, F. pinicola showed high antagonistic/antifungal activity toward test fungi by suppressing their average …
Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic Potential.
Ashraf SA, Elkhalifa AEO, Siddiqui AJ, Patel M, Awadelkareem AM, Snoussi M, Ashraf MS, Adnan M, Hadi S. Ashraf SA, et al. Molecules. 2020 Jun 12;25(12):2735. doi: 10.3390/molecules25122735. Molecules. 2020. PMID: 32545666 Free PMC article. Review.
Cordyceps is a rare naturally occurring entomopathogenic fungus usually found at high altitudes on the Himalayan plateau and a well-known medicinal mushroom in traditional Chinese medicine. Cordyceps contains various bioactive components, out of which, cordyc …
Cordyceps is a rare naturally occurring entomopathogenic fungus usually found at high altitudes on the Himalayan plateau and a well-known …
Disseminated Hormographiella aspergillata infection with involvement of the lung, brain, and small intestine following allogeneic hematopoietic stem cell transplantation: case report and literature review.
Nanno S, Nakane T, Okamura H, Nishimoto M, Koh H, Nakamae H, Ohsawa M, Yarita K, Kamei K, Hino M. Nanno S, et al. Transpl Infect Dis. 2016 Aug;18(4):611-6. doi: 10.1111/tid.12561. Epub 2016 Aug 2. Transpl Infect Dis. 2016. PMID: 27237466 Review.
Fungal growth from the biopsied lung was identified as H. aspergillata by morphology and the gene analysis. Although antifungal agents including voriconazole and liposomal amphotericin B were administered, he died of disseminated H. aspergillata infection. ...
Fungal growth from the biopsied lung was identified as H. aspergillata by morphology and the gene analysis. Although antifungal ag …
Breakthrough Hormographiella aspergillata Infection in a Patient with Acute Myeloid Leukemia Receiving Posaconazole Prophylaxis: A Case Report and Review.
Isabel Cristina RS, Diana A, Karen A. Isabel Cristina RS, et al. Mycopathologia. 2020 Dec;185(6):1069-1076. doi: 10.1007/s11046-020-00488-z. Epub 2020 Sep 3. Mycopathologia. 2020. PMID: 32880829 Review.
Breakthrough invasive infections occur in immunosuppressed patients while they are receiving antifungal agents for both prophylaxis and therapy. Under such conditions, unusual fungal infections emerge. ...
Breakthrough invasive infections occur in immunosuppressed patients while they are receiving antifungal agents for both prophy …
Schizophyllum commune sinusitis after allogeneic bone marrow transplantation for myelodysplastic syndrome: A case report and literature review.
Narazaki T, Nakashima Y, Tsukamoto Y, Nishida R, Tsuda M, Muta H, Kimura D, Masuda T, Takamatsu A, Kohashi K, Murakami D, Shiratsuchi M, Ogawa Y. Narazaki T, et al. Transpl Infect Dis. 2020 Feb;22(1):e13205. doi: 10.1111/tid.13205. Epub 2019 Nov 13. Transpl Infect Dis. 2020. PMID: 31674700 Review.
This case suggests the effectiveness of prompt surgical intervention with liposomal amphotericin B treatment for S commune sinusitis and the usefulness of genetic diagnosis for cases under antifungal treatment. (160 words)....
This case suggests the effectiveness of prompt surgical intervention with liposomal amphotericin B treatment for S commune sinusitis and the …
Antifungal Properties of Polycephalomyces nipponicus (Ascomycetes) against Candida albicans: Potential for Novel Therapeutic Development.
Thammawat S, Fowsantear W, Sangdee K, Sangdee A. Thammawat S, et al. Int J Med Mushrooms. 2025;27(1):81-89. doi: 10.1615/IntJMedMushrooms.2024056351. Int J Med Mushrooms. 2025. PMID: 39717920
Novel therapeutics are required due to its morphological alterations, biofilm development, and resistance to antifungal drugs. Polycephalomyces nipponicus, a traditional East Asian medicinal fungus, has shown potential as an antifungal agent. ...These finding …
Novel therapeutics are required due to its morphological alterations, biofilm development, and resistance to antifungal drugs. Polyce …
The Potential of Peroxidases Extracted from the Spent Mushroom (Flammulina velutipes) Substrate Significantly Degrade Mycotoxin Deoxynivalenol.
Tso KH, Lumsangkul C, Ju JC, Fan YK, Chiang HI. Tso KH, et al. Toxins (Basel). 2021 Jan 19;13(1):72. doi: 10.3390/toxins13010072. Toxins (Basel). 2021. PMID: 33478106 Free PMC article.
Little is known about the degradability of mycotoxin deoxynivalenol (DON) by the spent mushroom substrate (SMS)-derived manganese peroxidase (MnP) and lignin peroxidase (LiP) and its potential. ...
Little is known about the degradability of mycotoxin deoxynivalenol (DON) by the spent mushroom substrate (SMS)-derived manganese per …
Estimation of some trace metals, bioactive compounds, curative antimicrobial and antioxidant agents from Russula foetens and Russula cf. foetentoides.
Niazi AR, Shafique M, Imran M, Latif S. Niazi AR, et al. Pak J Pharm Sci. 2022 Sep;35(5):1371-1377. Pak J Pharm Sci. 2022. PMID: 36451566
The current study is an attempt to estimate minerals, antioxidant and antimicrobial activities of two medicinal mushrooms (Russula foetens and Russula cf. foetentoides) along with their mycochemicals. ...The highest antibacterial activity (27.8 0.152mm) was displaye …
The current study is an attempt to estimate minerals, antioxidant and antimicrobial activities of two medicinal mushrooms (Rus …
New Metabolites, Antifeedant, Insecticidal Activities, and Reciprocal Relationship Between Insect and Fungus from Endophyte Schizophyllum commune.
Wang CF, Yang XQ, Sun J, Wang T, Cui HR, Yang YB, Ding ZT. Wang CF, et al. Chem Biodivers. 2022 Jun;19(6):e202200130. doi: 10.1002/cbdv.202200130. Epub 2022 Jun 2. Chem Biodivers. 2022. PMID: 35580000
Five new bisabolane sesquiterpenes, a new polyketide, along with seven known compounds, were isolated from endophyte Schizophyllum commune associated with a famous medicinal and edible plant, Gastrodia elata. Most compounds 1-12, and extract indicated antifeedant activitie …
Five new bisabolane sesquiterpenes, a new polyketide, along with seven known compounds, were isolated from endophyte Schizophyllum commune a …
Taxonomy, Diversity and Cultivation of the Oudemansielloid/Xeruloid Taxa Hymenopellis, Mucidula, Oudemansiella, and Xerula with Respect to Their Bioactivities: A Review.
Niego AG, Raspé O, Thongklang N, Charoensup R, Lumyong S, Stadler M, Hyde KD. Niego AG, et al. J Fungi (Basel). 2021 Jan 13;7(1):51. doi: 10.3390/jof7010051. J Fungi (Basel). 2021. PMID: 33451109 Free PMC article. Review.
Polysaccharides, dihydro-citrinone phenol A acid, scalusamides, and acetylenic lactones such as xerulin, also have potential applications in the nutraceutical, pharmaceutical and medicinal market and should be further explored. Further studies are recommended to isolate hi …
Polysaccharides, dihydro-citrinone phenol A acid, scalusamides, and acetylenic lactones such as xerulin, also have potential applications in …
Antimicrobial activities of some mushrooms in Turkey.
Doğan HH, Duman R, Özkalp B, Aydin S. Doğan HH, et al. Pharm Biol. 2013 Jun;51(6):707-11. doi: 10.3109/13880209.2013.764327. Pharm Biol. 2013. PMID: 23675836 Free article.
(Russulaceae) are well-known species in Turkey, and are used both for food and traditional medicine. OBJECTIVE: The powdered fruit bodies of T. boudieri, A. brunnescens and L. vellereus were used to evaluate the antimicrobial activities. ...DISCUSSION AND CONCLUSION: Prese …
(Russulaceae) are well-known species in Turkey, and are used both for food and traditional medicine. OBJECTIVE: The powdered fruit bo …
New scientific approaches to cancer treatment: can medicinal mushrooms defeat the curse of the century?
Petrova RD. Petrova RD. Int J Med Mushrooms. 2012;14(1):1-20. doi: 10.1615/intjmedmushr.v14.i1.10. Int J Med Mushrooms. 2012. PMID: 22339703
Therefore, the pharmacological modulation of intracellular signal transduction pathways and the activation of transcription factors regulating gene expression represent a new and attractive therapeutic approach to cancer. It is already well established that medicinal mu …
Therefore, the pharmacological modulation of intracellular signal transduction pathways and the activation of transcription factors regulati …
Structure and ecological function of the soil microbiome associated with 'Sanghuang' mushrooms suffering from fungal diseases.
Xu W, Sun T, Du J, Jin S, Zhang Y, Bai G, Li W, Yin D. Xu W, et al. BMC Microbiol. 2023 Aug 12;23(1):218. doi: 10.1186/s12866-023-02965-z. BMC Microbiol. 2023. PMID: 37573330 Free PMC article.
BACKGROUND: The most serious challenges in medicinal 'Sanghuang' mushroom production are the fungal diseases caused by various molds. Application of biological agents has been regarded as a potential crop disease management strategy. Here, the soil microbiome …
BACKGROUND: The most serious challenges in medicinal 'Sanghuang' mushroom production are the fungal diseases caused by various …
Actin cytoskeletal inhibitor 19,20-epoxycytochalasin Q sensitizes yeast cells lacking ERG6 through actin-targeting and secondarily through disruption of lipid homeostasis.
Watchaputi K, Somboon P, Phromma-In N, Ratanakhanokchai K, Soontorngun N. Watchaputi K, et al. Sci Rep. 2021 Apr 8;11(1):7779. doi: 10.1038/s41598-021-87342-4. Sci Rep. 2021. PMID: 33833332 Free PMC article.
Repetitive uses of antifungals result in a worldwide crisis of drug resistance; therefore, natural fungicides with minimal side-effects are currently sought after. This study aimed to investigate antifungal property of 19, 20-epoxycytochalasin Q (ECQ), derived from …
Repetitive uses of antifungals result in a worldwide crisis of drug resistance; therefore, natural fungicides with minimal side-effec …
Antimicrobial Activity of Three Italian Strains of Morchella esculenta (Ascomycota).
Badalyan SM, Gharibyan NG, Iotti M, Zambonelli A. Badalyan SM, et al. Int J Med Mushrooms. 2024;26(2):43-55. doi: 10.1615/IntJMedMushrooms.2023051956. Int J Med Mushrooms. 2024. PMID: 38421695
Three genetically identified and morphologically characterized strains (MesAQ2-C, MesAQ6-2 and MesFI2-3) of the culinary-medicinal ascomycete mushroom Morchella esculenta (L.) Pers. collected in central-north Italy have been studied for their antifungal and a …
Three genetically identified and morphologically characterized strains (MesAQ2-C, MesAQ6-2 and MesFI2-3) of the culinary-medicinal as …
Antibiotic Guanacastane Diterpenoids with Two New Skeletons from Psathyrella candolleana Uncovered by Semisolid and Liquid Media.
Zhao TD, Yang XQ, Zhou J, Yang YB, Ding ZT. Zhao TD, et al. J Agric Food Chem. 2023 Feb 1;71(4):2006-2013. doi: 10.1021/acs.jafc.2c08176. Epub 2023 Jan 19. J Agric Food Chem. 2023. PMID: 36656976
The semisolid culture led to four structure types of the guanacastane diterpenoid. Compound 5 showed antifungal activity against phytopathogen Fusarium incarnatum with a minimum inhibitory concentration (MIC) of 8 mug/mL, while compound 4 showed significant antifungal …
The semisolid culture led to four structure types of the guanacastane diterpenoid. Compound 5 showed antifungal activity against phyt …
Hydroxyl substituted benzoic acid/cinnamic acid derivatives: Tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies.
Nazir Y, Saeed A, Rafiq M, Afzal S, Ali A, Latif M, Zuegg J, Hussein WM, Fercher C, Barnard RT, Cooper MA, Blaskovich MAT, Ashraf Z, Ziora ZM. Nazir Y, et al. Bioorg Med Chem Lett. 2020 Jan 1;30(1):126722. doi: 10.1016/j.bmcl.2019.126722. Epub 2019 Oct 24. Bioorg Med Chem Lett. 2020. PMID: 31732410
The hydroxyl substituted benzoic and cinnamic acid moieties of these precursors were incorporated into new chemotypes that displayed in vitro inhibitory effect against mushroom tyrosinase. The most active compound, (2-(3-methoxyphenoxy)-2-oxoethyl (E)-3-(4-hydroxyphenyl) a …
The hydroxyl substituted benzoic and cinnamic acid moieties of these precursors were incorporated into new chemotypes that displayed in vitr …
Benzoic acid derivatives with improved antifungal activity: Design, synthesis, structure-activity relationship (SAR) and CYP53 docking studies.
Berne S, Kovačič L, Sova M, Kraševec N, Gobec S, Križaj I, Komel R. Berne S, et al. Bioorg Med Chem. 2015 Aug 1;23(15):4264-4276. doi: 10.1016/j.bmc.2015.06.042. Epub 2015 Jun 25. Bioorg Med Chem. 2015. PMID: 26154240
Previously, we identified CYP53 as a fungal-specific target of natural phenolic antifungal compounds and discovered several inhibitors with antifungal properties. In this study, we performed similarity-based virtual screening and synthesis to obtain benzoic acid-der …
Previously, we identified CYP53 as a fungal-specific target of natural phenolic antifungal compounds and discovered several inhibitor …
Antioxidant and antimicrobial potentials of mycelial extracts of Hohenbuehelia myxotricha grown in different liquid culture media.
Krupodorova T, Barshteyn V, Sevindik M. Krupodorova T, et al. BioTechnologia (Pozn). 2022 Mar 24;103(1):19-28. doi: 10.5114/bta.2022.113912. eCollection 2022. BioTechnologia (Pozn). 2022. PMID: 36605378 Free PMC article.
In addition to their nutritional properties, mushrooms have emerged as a health supplement because of their medicinal potential. Many studies have shown that mushrooms exhibit important biological activities. ...GPY medium was more suitable for the synthesis …
In addition to their nutritional properties, mushrooms have emerged as a health supplement because of their medicinal potentia …
Volvariella volvacea brain Abscess in an immunocompromised host-An emerging fungal pathogen in Asia.
Alagha R, Tham SM, Chew KL, Cheng JWS, Lian DW, Vathsala A, Lum LHW. Alagha R, et al. J Mycol Med. 2022 Aug;32(3):101272. doi: 10.1016/j.mycmed.2022.101272. Epub 2022 Mar 4. J Mycol Med. 2022. PMID: 35279454
Volvariella volvacea is a fungus found in tropical regions, commonly associated with straw mushrooms. This is a 50-year-old Singaporean female post living donor renal transplant who presented with fever, cough and headache. ...The pathogenicity of this rare fungus in immun …
Volvariella volvacea is a fungus found in tropical regions, commonly associated with straw mushrooms. This is a 50-year-old Singapore …
Cloning and Characterization of Promoters of the Fungal Immunomodulatory Protein Genes from Ganoderma spp. (Agaricomycetes) and Their Response to Methyl Jasmonate and Salicylic Acid.
Li QZ, Chang YZ, Su KQ, Wang XL, Bai XH, Zhou XW. Li QZ, et al. Int J Med Mushrooms. 2018;20(2):177-189. doi: 10.1615/IntJMedMushrooms.2018025451. Int J Med Mushrooms. 2018. PMID: 29773009
Ganoderma mushrooms for medicinal use contain various bioactive compounds, but the genetic elements available for these medicinal mushrooms are still limited. ...
Ganoderma mushrooms for medicinal use contain various bioactive compounds, but the genetic elements available for these med …
Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal "mushroom".
Glamočlija J, Ćirić A, Nikolić M, Fernandes Â, Barros L, Calhelha RC, Ferreira IC, Soković M, van Griensven LJ. Glamočlija J, et al. J Ethnopharmacol. 2015 Mar 13;162:323-32. doi: 10.1016/j.jep.2014.12.069. Epub 2015 Jan 7. J Ethnopharmacol. 2015. PMID: 25576897
ETHNOPHARMACOLOGICAL RELEVANCE: In Russian traditional medicine, an extract from the mushroom Inonotus obliquus (Fr.) Pil at is used as an anti-tumor medicine and diuretic. ...CONCLUSIONS: As the Inonotus obliquus presence in Chaga conks is limited, further p …
ETHNOPHARMACOLOGICAL RELEVANCE: In Russian traditional medicine, an extract from the mushroom Inonotus obliquus (Fr.) Pil at i …
Enhancing Cordycepin in Functional Porridge through Rice Varietal Fermentation with Cordyceps militaris (Ascomycetes) and Utilizing Non-Targeted Metabolomics for Process Enhancement.
Liu ML, Chien TY, Lo HC, Hsu TH, Lee SC, Chao SC. Liu ML, et al. Int J Med Mushrooms. 2024;26(8):59-73. doi: 10.1615/IntJMedMushrooms.2024054150. Int J Med Mushrooms. 2024. PMID: 38967211
Cordyceps militaris, a medicinal fungus rich in cordycepin, shows promise in treating diseases such as cancer, respiratory issues, and COVID-19. ...
Cordyceps militaris, a medicinal fungus rich in cordycepin, shows promise in treating diseases such as cancer, respiratory issues, an …
Functional convergence and divergence of mating-type genes fulfilling in Cordyceps militaris.
Lu Y, Xia Y, Luo F, Dong C, Wang C. Lu Y, et al. Fungal Genet Biol. 2016 Mar;88:35-43. doi: 10.1016/j.fgb.2016.01.013. Epub 2016 Jan 23. Fungal Genet Biol. 2016. PMID: 26812121
Sexual fruiting bodies of the ascomycete fungus Cordyceps militaris have been widely consumed as edible and medicinal mushrooms, whereas the regulation of fruiting-body development and sex in this fungus remain elusive. ...
Sexual fruiting bodies of the ascomycete fungus Cordyceps militaris have been widely consumed as edible and medicinal mushrooms …
Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScopeⓇ-Global Registry for Emerging Fungal Infections.
Salmanton-García J, Koehler P, Kindo A, Falces-Romero I, García-Rodríguez J, Ráčil Z, Chen SC, Klimko N, Desoubeaux G, Thompson GR , III, Benítez-Peñuela MÁ, Rodríguez JY, Sheppard DC, Hoenigl M, Le Govic Y, Badali H, Baddley JW, Chander J, Ingram PR, Pakstis DL, Mellinghoff SC, Atıcı S, Cesaro S, Chakrabarti A, Dupont D, González GM, Hatvani L, Herbrecht R, Klyasova G, Lass-Flörl C, Mareș M, Mullane K, Vinh DC, Wisplinghoff H, Lackner M, Cornely OA, Seidel D; ECMM/ISHAM working group. Salmanton-García J, et al. J Infect. 2020 Nov;81(5):802-815. doi: 10.1016/j.jinf.2020.08.015. Epub 2020 Aug 13. J Infect. 2020. PMID: 32798532
METHODS: Extremely rare IFI collected in the FungiScope(R) registry were grouped as Dematiaceae, Hypocreales, Saccharomycetales, Eurotiales, Dermatomycetes, Agaricales, and Mucorales. RESULTS: Between 2003 and June 2019, 186 extremely rare IFI were documented in FungiScope …
METHODS: Extremely rare IFI collected in the FungiScope(R) registry were grouped as Dematiaceae, Hypocreales, Saccharomycetales, Eurotiales, …
Antibacterial and Antifungal Activities of Lectin Extracted from Fruiting Bodies of the Korean Cauliflower Medicinal Mushroom, Sparassis latifolia (Agaricomycetes).
Chandrasekaran G, Lee YC, Park H, Wu Y, Shin HJ. Chandrasekaran G, et al. Int J Med Mushrooms. 2016;18(4):291-9. doi: 10.1615/IntJMedMushrooms.v18.i4.20. Int J Med Mushrooms. 2016. PMID: 27481295
In this article we describe the isolation and characterization of a novel lectin from fruiting bodies of the mushroom Sparassis latifolia. The antibacterial activity of the purified lectin against Escherichia coli and resistant strains of Staphylococcus aureus and Pseudomo …
In this article we describe the isolation and characterization of a novel lectin from fruiting bodies of the mushroom Sparassis latif …
Invasive Fungal Sinusitis by Lasiodiplodia theobromae in an Patient with Aplastic Anemia: An Extremely Rare Case Report and Literature Review.
Gu HJ, Kim YJ, Lee HJ, Dong SH, Kim SW, Huh HJ, Ki CS. Gu HJ, et al. Mycopathologia. 2016 Dec;181(11-12):901-908. doi: 10.1007/s11046-016-0062-z. Epub 2016 Sep 20. Mycopathologia. 2016. PMID: 27650099 Review.
The patient was presumed to have iatrogenic aplastic anemia due to mushroom toxicity. He began treatment for multiple organ infections with broad-spectrum antibiotics and antifungal agents. ...
The patient was presumed to have iatrogenic aplastic anemia due to mushroom toxicity. He began treatment for multiple organ infection …
Medicinal and antimicrobial role of the oyster culinary-medicinal mushroom Pleurotus ostreatus (higher Basidiomycetes) cultivated on banana agrowastes in India.
Kunjadia PD, Nagee A, Pandya PY, Mukhopadhyaya PN, Sanghvi GV, Dave GS. Kunjadia PD, et al. Int J Med Mushrooms. 2014;16(3):227-38. doi: 10.1615/intjmedmushr.v16.i3.30. Int J Med Mushrooms. 2014. PMID: 24941164
Oyster mushrooms, species of the genus Pleurotus, are recognized for producing secondary metabolites with important medicinal properties. ...Moreover, banana agrowaste could be a significant economic source for the production of the oyster mushroom P. ostreat …
Oyster mushrooms, species of the genus Pleurotus, are recognized for producing secondary metabolites with important medicinal …
Allergic bronchopulmonary mycosis due to Schizophyllum commune in a patient with chronic hepatitis B.
Xu R, Zhang J, Zheng J, Wu Q. Xu R, et al. J Infect Dev Ctries. 2024 Mar 31;18(3):488-494. doi: 10.3855/jidc.18024. J Infect Dev Ctries. 2024. PMID: 38635609 Free article.
Most patients have good prognosis with a combination of proper antifungal therapy and hormonal therapy....
Most patients have good prognosis with a combination of proper antifungal therapy and hormonal therapy....
In vitro evaluation of Cordyceps militaris as a potential radioprotective agent.
Jeong MH, Park YS, Jeong DH, Lee CG, Kim JS, Oh SJ, Jeong SK, Yang K, Jo WS. Jeong MH, et al. Int J Mol Med. 2014 Nov;34(5):1349-57. doi: 10.3892/ijmm.2014.1901. Epub 2014 Aug 18. Int J Mol Med. 2014. PMID: 25176413
Cordyceps militaris (C. militaris), a traditional medicinal mushroom, produces the bioactive compound, cordycepin (3'-deoxyadenosine) and has multiple pharmacological activities, such as antitumor, antimetastatic, antioxidant and immunomodulatory effects. ...
Cordyceps militaris (C. militaris), a traditional medicinal mushroom, produces the bioactive compound, cordycepin (3'-deoxyade …
A peptide with HIV-1 reverse transcriptase inhibitory activity from the medicinal mushroom Russula paludosa.
Wang J, Wang HX, Ng TB. Wang J, et al. Peptides. 2007 Mar;28(3):560-5. doi: 10.1016/j.peptides.2006.10.004. Epub 2006 Nov 17. Peptides. 2007. PMID: 17113195
Hot water extracts of 16 species of mushrooms, including both edible and medicinal mushrooms, were screened for human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) inhibitory activity. ...The peptide was devoid of hemagglutinating, ribonuclease, …
Hot water extracts of 16 species of mushrooms, including both edible and medicinal mushrooms, were screened for human i …
Uridine from Pleurotus giganteus and Its Neurite Outgrowth Stimulatory Effects with Underlying Mechanism.
Phan CW, David P, Wong KH, Naidu M, Sabaratnam V. Phan CW, et al. PLoS One. 2015 Nov 13;10(11):e0143004. doi: 10.1371/journal.pone.0143004. eCollection 2015. PLoS One. 2015. PMID: 26565787 Free PMC article.
Neurodegenerative diseases are linked to neuronal cell death and impairment of neurite outgrowth. An edible mushroom, Pleurotus giganteus was found to stimulate neurite outgrowth in vitro but the chemical constituents and the underlying mechanism is yet to be elucidated. . …
Neurodegenerative diseases are linked to neuronal cell death and impairment of neurite outgrowth. An edible mushroom, Pleurotus gigan …
A detailed comparative study between chemical and bioactive properties of Ganoderma lucidum from different origins.
Stojković DS, Barros L, Calhelha RC, Glamočlija J, Ćirić A, van Griensven LJ, Soković M, Ferreira IC. Stojković DS, et al. Int J Food Sci Nutr. 2014 Feb;65(1):42-7. doi: 10.3109/09637486.2013.832173. Epub 2013 Sep 11. Int J Food Sci Nutr. 2014. PMID: 24020451
This species was chosen because of its worldwide use as medicinal mushroom. Higher amounts of sugars were found in GS, while higher amounts of organic acids were recorded in GCN. ...Both samples possessed antibacterial and antifungal activities, in some cases …
This species was chosen because of its worldwide use as medicinal mushroom. Higher amounts of sugars were found in GS, while h …
Cordyceps militaris Enhances Cell-Mediated Immunity in Healthy Korean Men.
Kang HJ, Baik HW, Kim SJ, Lee SG, Ahn HY, Park JS, Park SJ, Jang EJ, Park SW, Choi JY, Sung JH, Lee SM. Kang HJ, et al. J Med Food. 2015 Oct;18(10):1164-72. doi: 10.1089/jmf.2014.3350. Epub 2015 Aug 18. J Med Food. 2015. PMID: 26284906 Clinical Trial.
Cordyceps militaris is a mushroom traditionally used for diverse pharmaceutical purposes in East Asia, including China, and has been found to be effective for enhancing immunity through various types of animal testing. ...
Cordyceps militaris is a mushroom traditionally used for diverse pharmaceutical purposes in East Asia, including China, and has been …
Gloeostereum cimri, a novel shelf fungus isolated from a human pulmonary cyst.
Ahmed SA, de Hoog S, Kim J, Crozier J, Thomas SE, Stielow B, Stevens DA. Ahmed SA, et al. Emerg Microbes Infect. 2020 Dec;9(1):1114-1122. doi: 10.1080/22221751.2020.1769499. Emerg Microbes Infect. 2020. PMID: 32475225 Free PMC article.
Filamentous basidiomycetes are uncommon agents of human diseases, despite their ubiquitous presence in the environment. We present a case of symptomatic pulmonary infection in a 38-year-old male with cough and fever; a thin-walled cyst in the posterior left upper pulmonary …
Filamentous basidiomycetes are uncommon agents of human diseases, despite their ubiquitous presence in the environment. We present a …
Synergistic property of cordycepin in cultivated Cordyceps militaris-mediated apoptosis in human leukemia cells.
Chou SM, Lai WJ, Hong TW, Lai JY, Tsai SH, Chen YH, Yu SH, Kao CH, Chu R, Ding ST, Li TK, Shen TL. Chou SM, et al. Phytomedicine. 2014 Oct 15;21(12):1516-24. doi: 10.1016/j.phymed.2014.07.014. Epub 2014 Aug 28. Phytomedicine. 2014. PMID: 25442260
Cordyceps militaris is a well-known Chinese traditional medicinal mushroom frequently used for tonics and recently of a potential interest for cancer intervention. ...
Cordyceps militaris is a well-known Chinese traditional medicinal mushroom frequently used for tonics and recently of a potent …
Chemical Composition and Antimicrobial Properties of Morchella crassipes (Ascomycota) from Kashmir Valley (India).
Talie M, War JM, Nisa AU, Dar AH, Wani AH, Bhat MY. Talie M, et al. Int J Med Mushrooms. 2024;26(6):39-51. doi: 10.1615/IntJMedMushrooms.2024053250. Int J Med Mushrooms. 2024. PMID: 38801086
In that view, current research work was designed to evaluate the biochemical composition and medicinal properties of Morchella crassipes mushroom. The mycochemical screening of aqueous extract exposed the incidence of glycosides, free amino acids and proteins, alkal …
In that view, current research work was designed to evaluate the biochemical composition and medicinal properties of Morchella crassi …
An examination of antibacterial and antifungal properties of constituents of Shiitake (Lentinula edodes) and oyster (Pleurotus ostreatus) mushrooms.
Hearst R, Nelson D, McCollum G, Millar BC, Maeda Y, Goldsmith CE, Rooney PJ, Loughrey A, Rao JR, Moore JE. Hearst R, et al. Complement Ther Clin Pract. 2009 Feb;15(1):5-7. doi: 10.1016/j.ctcp.2008.10.002. Epub 2008 Dec 2. Complement Ther Clin Pract. 2009. PMID: 19161947
However, the emergence of multi-drug resistant pathogens now presents an increasing global challenge to both human and veterinary medicine. It is now widely acknowledged that there is a need to develop novel antimicrobial agents to minimize the threat of further ant …
However, the emergence of multi-drug resistant pathogens now presents an increasing global challenge to both human and veterinary medicin …
Comparative Assessment of Antifungal and Antibacterial Activities of Crude Extracts of the King Tuber Culinary-Medicinal Mushroom, Pleurotus tuber-regium (Agaricomycetes) from Cameroon.
Metsebing BP, Oba R, Mossebo DC, Fonkui TY, Tsigain FT, Fotsing MCD, Mungoh TC, Ndinteh DN. Metsebing BP, et al. Int J Med Mushrooms. 2020;22(4):359-366. doi: 10.1615/IntJMedMushrooms.2020034178. Int J Med Mushrooms. 2020. PMID: 32558500
Antifungal and antibacterial activities of crude extracts of carpophore compared with those of sclerotium of Pleurotus tuber-regium were investigated on 11 species of bacterial and 3 fungal human pathogens. ...
Antifungal and antibacterial activities of crude extracts of carpophore compared with those of sclerotium of Pleurotus tuber-regium w …
Preparation and Characterization of Carboxymethyl Cellulose-Based Bioactive Composite Films Modified with Fungal Melanin and Carvacrol.
Łopusiewicz Ł, Kwiatkowski P, Drozłowska E, Trocer P, Kostek M, Śliwiński M, Polak-Śliwińska M, Kowalczyk E, Sienkiewicz M. Łopusiewicz Ł, et al. Polymers (Basel). 2021 Feb 5;13(4):499. doi: 10.3390/polym13040499. Polymers (Basel). 2021. PMID: 33562865 Free PMC article.
Herein, biopolymer-based (carboxymethyl cellulose-CMC) bioactive films were prepared by the addition, alone or in combination, of carvacrol and fungal melanin isolated from champignon mushroom (Agaricus bisporus) agro-industrial residues. The mechanical, optical, thermal, …
Herein, biopolymer-based (carboxymethyl cellulose-CMC) bioactive films were prepared by the addition, alone or in combination, of carvacrol …
Biological activities and DNA interactions of Amanita ovoidea.
Doğan HH, Arslan E. Doğan HH, et al. Pharm Biol. 2015;53(9):1386-90. doi: 10.3109/13880209.2014.982303. Epub 2015 Apr 15. Pharm Biol. 2015. PMID: 25874387 Free article.
This species is also known in Turkey and people consume it extensively. OBJECTIVE: To evaluate medicinal importance of A. ovoidea for human health, to explain the effect of mushroom extracts on bacterial DNA, and to find preventive role on bacterial disease. ...DISC …
This species is also known in Turkey and people consume it extensively. OBJECTIVE: To evaluate medicinal importance of A. ovoidea for …
Ethanolic extract from fruiting bodies of Cordyceps militaris HL8 exhibits cytotoxic activities against cancer cells, skin pathogenic yeasts, and postharvest pathogen Penicillium digitatum.
Vu TX, Tran TB, Vu HH, Le YTH, Nguyen PH, Do TT, Nguyen TH, Tran VT. Vu TX, et al. Arch Microbiol. 2024 Feb 13;206(3):97. doi: 10.1007/s00203-024-03833-8. Arch Microbiol. 2024. PMID: 38349544
Cordyceps militaris is a well-known medicinal mushroom in Asian countries. This edible fungus has been widely exploited for traditional medicine and functional food production. ...Our work provides a promising monokaryotic C. militaris strain as a bioresource …
Cordyceps militaris is a well-known medicinal mushroom in Asian countries. This edible fungus has been widely exploited for tr …
Pediococcus pentosaceus-Fermented Cordyceps militaris Inhibits Inflammatory Reactions and Alleviates Contact Dermatitis.
Kwon HK, Song MJ, Lee HJ, Park TS, Kim MI, Park HJ. Kwon HK, et al. Int J Mol Sci. 2018 Nov 7;19(11):3504. doi: 10.3390/ijms19113504. Int J Mol Sci. 2018. PMID: 30405049 Free PMC article.
Cordyceps militaris is a medicinal mushroom used to treat immune-related diseases in East Asia. We investigated the anti-inflammatory effect of the extract of C. militaris grown on germinated Rhynchosia nulubilis (GRC) fermented with Pediococcus pentosaceus ON89A is …
Cordyceps militaris is a medicinal mushroom used to treat immune-related diseases in East Asia. We investigated the anti-infla …
Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Inhibits Candida Biofilms: A Metabolomic Approach.
Bhardwaj A, Gupta P, Kumar N, Mishra J, Kumar A, Rakhee R, Misra K. Bhardwaj A, et al. Int J Med Mushrooms. 2017;19(8):685-696. doi: 10.1615/IntJMedMushrooms.2017021225. Int J Med Mushrooms. 2017. PMID: 29199568
This article presents a comparative gas chromatography (GC)-mass spectrometry (MS)-based metabolomic analysis of mycelia and fruiting bodies of the medicinal mushroom Ganoderma lucidum. Three aqueous extracts-mycelia, fruiting bodies, and a mixture of them-and their …
This article presents a comparative gas chromatography (GC)-mass spectrometry (MS)-based metabolomic analysis of mycelia and fruiting bodies …
Selenium Biofortification and Antioxidant Activity in Cordyceps militaris Supplied with Selenate, Selenite, or Selenomethionine.
Hu T, Liang Y, Zhao G, Wu W, Li H, Guo Y. Hu T, et al. Biol Trace Elem Res. 2019 Feb;187(2):553-561. doi: 10.1007/s12011-018-1386-y. Epub 2018 May 31. Biol Trace Elem Res. 2019. PMID: 29855849
Selenium (Se) is an essential trace element with multiple functions that may help mitigate adverse health conditions. Cordyceps militaris is an edible mushroom with medicinal properties. The experiment was conducted under artificial cultivation, with five Se concent …
Selenium (Se) is an essential trace element with multiple functions that may help mitigate adverse health conditions. Cordyceps militaris is …
Brefeldin A is an estrogenic, Erk1/2-activating component in the extract of Agaricus blazei mycelia.
Dong S, Furutani Y, Kimura S, Zhu Y, Kawabata K, Furutani M, Nishikawa T, Tanaka T, Masaki T, Matsuoka R, Kiyama R. Dong S, et al. J Agric Food Chem. 2013 Jan 9;61(1):128-36. doi: 10.1021/jf304546a. Epub 2012 Dec 20. J Agric Food Chem. 2013. PMID: 23215459
Furthermore, BFA was found in the mycelium but not fruiting body of A. blazei, suggesting the potential use of ABE for therapeutics and its supplementary use in traditional medicines and functional foods....
Furthermore, BFA was found in the mycelium but not fruiting body of A. blazei, suggesting the potential use of ABE for therapeutics and its …
Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina.
Jenssen M, Kristoffersen V, Motiram-Corral K, Isaksson J, Rämä T, Andersen JH, Hansen EH, Hansen KØ. Jenssen M, et al. Molecules. 2021 Dec 13;26(24):7560. doi: 10.3390/molecules26247560. Molecules. 2021. PMID: 34946641 Free PMC article.
Compound 1 was evaluated for antibacterial activities against a panel of five bacteria, its ability to inhibit bacterial biofilm formation, for antifungal activity against Candida albicans, and for cytotoxic activities against malignant and non-malignant human cell lines. …
Compound 1 was evaluated for antibacterial activities against a panel of five bacteria, its ability to inhibit bacterial biofilm formation, …
Antifungal and Anticancer Activities of a Protein from the Mushroom Cordyceps militaris.
Park BT, Na KH, Jung EC, Park JW, Kim HH. Park BT, et al. Korean J Physiol Pharmacol. 2009 Feb;13(1):49-54. doi: 10.4196/kjpp.2009.13.1.49. Epub 2009 Feb 28. Korean J Physiol Pharmacol. 2009. PMID: 19885026 Free PMC article.
The mushroom Cordyceps militaris has been used for a long time in eastern Asia as a nutraceutical and in traditional Chinese medicine as a treatment for cancer patients. ...These results indicate that C. militaris represents a source of a novel protein that might be …
The mushroom Cordyceps militaris has been used for a long time in eastern Asia as a nutraceutical and in traditional Chinese medic …
Antagonistic mechanism of Bacillus velezensis HX0039 as a biocontrol agent against Trichoderma virens-induced "Sanghuang" green mold.
Zhang Y, Gao W, Zhang H, Sun T, Yang H, Liu Y, Han X, Yin D, Xu W. Zhang Y, et al. Appl Environ Microbiol. 2025 Aug 20;91(8):e0000525. doi: 10.1128/aem.00005-25. Epub 2025 Jul 8. Appl Environ Microbiol. 2025. PMID: 40626662 Free PMC article.
Our results will provide insights into the antifungal mechanisms of B. velezensis HX0039 and will facilitate the further application of this strain as a biocontrol agent against T. virens-induced "Sanghuang" green mold.IMPORTANCE"Sanghuang" mushroom is a valuable ed …
Our results will provide insights into the antifungal mechanisms of B. velezensis HX0039 and will facilitate the further application …
Two New Triterpenes from Basidiomata of the Medicinal and Edible Mushroom, Laetiporus sulphureus.
Hassan K, Matio Kemkuignou B, Stadler M. Hassan K, et al. Molecules. 2021 Nov 24;26(23):7090. doi: 10.3390/molecules26237090. Molecules. 2021. PMID: 34885672 Free PMC article.
The structures of the isolated compounds were elucidated based on their 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data in combination with high-resolution electrospray mass spectrometric (HR-ESIMS) data. Laetiporin C exhibited weak antifungal activity agains …
The structures of the isolated compounds were elucidated based on their 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data in com …
Cordycepin Attenuates Palmitic Acid-Induced Inflammation and Apoptosis of Vascular Endothelial Cells through Mediating PI3K/Akt/eNOS Signaling Pathway.
Ku CW, Ho TJ, Huang CY, Chu PM, Ou HC, Hsieh PL. Ku CW, et al. Am J Chin Med. 2021;49(7):1703-1722. doi: 10.1142/S0192415X21500804. Epub 2021 Sep 7. Am J Chin Med. 2021. PMID: 34488549
A well-known medicinal mushroom in the field of traditional Chinese medicine, Cordyceps sinensis, is a rare natural-occurring entomopathogenic fungus, and it typically grows at high altitudes on the plateau of the Himalayan. ...
A well-known medicinal mushroom in the field of traditional Chinese medicine, Cordyceps sinensis, is a rare natural-occ …
Immunostimulatory effects of cordycepin-enriched WIB-801CE from Cordyceps militaris in splenocytes and cyclophosphamide-induced immunosuppressed mice.
Shin JS, Chung SH, Lee WS, Lee JY, Kim JL, Lee KT. Shin JS, et al. Phytother Res. 2018 Jan;32(1):132-139. doi: 10.1002/ptr.5960. Epub 2017 Nov 23. Phytother Res. 2018. PMID: 29168246
The medicinal mushroom Cordyceps militaris has been reported to possess anticancer and immunomodulatory effects. ...
The medicinal mushroom Cordyceps militaris has been reported to possess anticancer and immunomodulatory effects. ...
(1, 3)-beta-D-Glucan in bronchoalveolar lavage fluid: a useful biomarker in diagnosis of invasive pulmonary infection caused by Hormographiella aspergillata?
Ye H, He J, Huang J, Chu P, Liu J, Poon RW, Xing F, Lo SK, Lau RW, Chan JF, Lau SK, Chiu KH. Ye H, et al. Diagn Pathol. 2024 Dec 28;19(1):168. doi: 10.1186/s13000-024-01589-9. Diagn Pathol. 2024. PMID: 39732699 Free PMC article.
Hormographiella aspergillata is a rare hyaline mold causing invasive fungal infection in humans, until the frequent use of antifungal prophylaxis in immunocompromised hosts. Due to the high mortality of H. aspergillata infection, early recognition and treatment are crucial …
Hormographiella aspergillata is a rare hyaline mold causing invasive fungal infection in humans, until the frequent use of antifungal …
Hormographiella aspergillata pulmonary infections: Detection and identification of the fungus using pan-fungal PCR assays and DNA sequencing.
Nevez G, Guillerm G, Talarmin JP, Quinio D, Iriart X, Lissillour PL, Rezig S, Fangous MS, Ranty M, Bodenes L, Aubron C, Couturier MA, Le Gal S. Nevez G, et al. J Mycol Med. 2024 Mar;34(1):101463. doi: 10.1016/j.mycmed.2024.101463. Epub 2024 Feb 4. J Mycol Med. 2024. PMID: 38342037
She was treated with liposomal amphotericin B and/or voriconazole until switching to isavuconazole on d298 due to side-effects. This antifungal treatment was maintained until d717 and then discontinued, the patient being considered as cured. ...
She was treated with liposomal amphotericin B and/or voriconazole until switching to isavuconazole on d298 due to side-effects. This anti …
Effects of Selenium Presence in Mycelia of Ganoderma species (Higher Basidiomycetes) on Their Medicinal Properties.
Milovanović I, Stajić M, Stanojković T, Knežević A, Vukojević J. Milovanović I, et al. Int J Med Mushrooms. 2015;17(1):11-20. doi: 10.1615/intjmedmushrooms.v17.i1.20. Int J Med Mushrooms. 2015. PMID: 25746402
This study aimed to research the antifungal, antioxidant, and cytotoxic potential of Ganoderma applanatum and Ganoderma lucidum mycelial extracts as well as the possible effect of Se enrichment on these activities. ...
This study aimed to research the antifungal, antioxidant, and cytotoxic potential of Ganoderma applanatum and Ganoderma lucidum mycel …
The Inhibitory Effect of Cordycepin on the Proliferation of MCF-7 Breast Cancer Cells, and its Mechanism: An Investigation Using Network Pharmacology-Based Analysis.
Lee D, Lee WY, Jung K, Kwon YS, Kim D, Hwang GS, Kim CE, Lee S, Kang KS. Lee D, et al. Biomolecules. 2019 Aug 23;9(9):407. doi: 10.3390/biom9090407. Biomolecules. 2019. PMID: 31450828 Free PMC article.
Cordycepsmilitaris is a well-known medicinal mushroom. It is non-toxic and has clinical health benefits including cancer inhibition. ...
Cordycepsmilitaris is a well-known medicinal mushroom. It is non-toxic and has clinical health benefits including cancer inhib …
The Inhibitory Effect of Cordycepin on the Proliferation of MCF-7 Breast Cancer Cells, and its Mechanism: An Investigation Using Network Pharmacology-Based Analysis.
Lee D, Lee WY, Jung K, Kwon YS, Kim D, Hwang GS, Kim CE, Lee S, Kang KS. Lee D, et al. Biomolecules. 2019 Aug 26;9(9):414. doi: 10.3390/biom9090414. Biomolecules. 2019. PMID: 31454995 Free PMC article.
Cordyceps militaris is a well-known medicinal mushroom. It is non-toxic and has clinical health benefits including cancer inhibition. ...
Cordyceps militaris is a well-known medicinal mushroom. It is non-toxic and has clinical health benefits including cancer inhi …
Lipid and fatty acid profile of the edible fungus Laetiporus sulphurous. Antifungal and antibacterial properties.
Sinanoglou VJ, Zoumpoulakis P, Heropoulos G, Proestos C, Ćirić A, Petrovic J, Glamoclija J, Sokovic M. Sinanoglou VJ, et al. J Food Sci Technol. 2015 Jun;52(6):3264-72. doi: 10.1007/s13197-014-1377-8. Epub 2014 Apr 30. J Food Sci Technol. 2015. PMID: 26028707 Free PMC article.
Total lipids were found to contain high unsaturated degree fatty acids (UFA/SFA>3.4) and dominated of C18:2omega-6, C18:1omega-9 and C16:0 fatty acids. Antibacterial and antifungal properties of mushrooms' lipid extracts from two different solvents were also exam …
Total lipids were found to contain high unsaturated degree fatty acids (UFA/SFA>3.4) and dominated of C18:2omega-6, C18:1omega-9 and C16: …
A novel lectin with antiproliferative activity from the medicinal mushroom Pholiota adiposa.
Zhang GQ, Sun J, Wang HX, Ng TB. Zhang GQ, et al. Acta Biochim Pol. 2009;56(3):415-21. Epub 2009 Jul 27. Acta Biochim Pol. 2009. PMID: 19636442
Little was known about biological activities of compounds from the medicinal mushroom of the genus Pholiota. A lectin from the Pholiota adiposa has now been isolated and its properties tested. ...In the case of the lectin from P. aurivella, its antifungal, an …
Little was known about biological activities of compounds from the medicinal mushroom of the genus Pholiota. A lectin from the …
Cordycepin Downregulates Cdk-2 to Interfere with Cell Cycle and Increases Apoptosis by Generating ROS in Cervical Cancer Cells: in vitro and in silico Study.
Tania M, Shawon J, Saif K, Kiefer R, Khorram MS, Halim MA, Khan MA. Tania M, et al. Curr Cancer Drug Targets. 2019;19(2):152-159. doi: 10.2174/1568009618666180905095356. Curr Cancer Drug Targets. 2019. PMID: 30182857
BACKGROUND: Cordycepin is a small molecule from medicinal mushroom Cordyceps, which has been reported for anticancer properties. OBJECTIVE: In this study, we have focused on the investigation of cordycepin effect on cervical cancer cells with further clarification o …
BACKGROUND: Cordycepin is a small molecule from medicinal mushroom Cordyceps, which has been reported for anticancer propertie …
Metabolomic profiling reveals enrichment of cordycepin in senescence process of Cordyceps militaris fruit bodies.
Oh J, Yoon DH, Shrestha B, Choi HK, Sung GH. Oh J, et al. J Microbiol. 2019 Jan;57(1):54-63. doi: 10.1007/s12275-019-8486-z. Epub 2018 Dec 29. J Microbiol. 2019. PMID: 30594983
Cordyceps militaris is a species of Cordyceps that is classified in the Cordycipitaceae family and is well known in East Asia as a traditional medicinal mushroom. Its artificial fruit body has been widely cultivated for commercial use in cosmetics, functional food, …
Cordyceps militaris is a species of Cordyceps that is classified in the Cordycipitaceae family and is well known in East Asia as a tradition …
Lentin, a novel and potent antifungal protein from shitake mushroom with inhibitory effects on activity of human immunodeficiency virus-1 reverse transcriptase and proliferation of leukemia cells.
Ngai PH, Ng TB. Ngai PH, et al. Life Sci. 2003 Nov 14;73(26):3363-74. doi: 10.1016/j.lfs.2003.06.023. Life Sci. 2003. PMID: 14572878
From the fruiting bodies of the edible mushroom Lentinus edodes, a novel protein designated lentin with potent antifungal activity was isolated. ...
From the fruiting bodies of the edible mushroom Lentinus edodes, a novel protein designated lentin with potent antifungal acti …
Determination of antimicrobial effect, antioxidant activity and phenolic contents of desert truffle in Turkey.
Doğan HH, Aydın S. Doğan HH, et al. Afr J Tradit Complement Altern Med. 2013 May 16;10(4):52-8. eCollection 2013. Afr J Tradit Complement Altern Med. 2013. PMID: 24146501 Free PMC article.
Pers., is a famous macrofungus in the world as well as in Turkey for its pleasant aroma and flavour. People believe that this mushroom has some medicinal properties. Therefore, it is consumed as food and for medicinal purposes. ...
Pers., is a famous macrofungus in the world as well as in Turkey for its pleasant aroma and flavour. People believe that this mushroom …
Sustained antimicrobial polymer film from γ-CD-MOF humidity switch for fruit and vegetable preservation.
Yu W, Wang G, Chen H, Mu H, Niu B, Han Y, Wang L, Chen H, Gao H. Yu W, et al. Food Chem. 2025 Jul 1;479:143856. doi: 10.1016/j.foodchem.2025.143856. Epub 2025 Mar 11. Food Chem. 2025. PMID: 40086383
The preservation experiment maintained the quality of strawberry and Agaricus bisporus mushroom. This strategy holds the potential to broaden the application scope and enhance the utility of CD-MOF in food preservation....
The preservation experiment maintained the quality of strawberry and Agaricus bisporus mushroom. This strategy holds the potential to …
Anti-inflammatory effects of cordycepin via suppression of inflammatory mediators in BV2 microglial cells.
Jeong JW, Jin CY, Kim GY, Lee JD, Park C, Kim GD, Kim WJ, Jung WK, Seo SK, Choi IW, Choi YH. Jeong JW, et al. Int Immunopharmacol. 2010 Dec;10(12):1580-6. doi: 10.1016/j.intimp.2010.09.011. Epub 2010 Oct 14. Int Immunopharmacol. 2010. PMID: 20937401
Cordyceps militaris, a traditional medicinal mushroom, produces the bioactive compound cordycepin (3'-deoxyadenosine). Although cordycepin has been shown to have pharmacological, immunological stimulating, anti-cancer, and anti-inflammatory activities, its activitie …
Cordyceps militaris, a traditional medicinal mushroom, produces the bioactive compound cordycepin (3'-deoxyadenosine). Althoug …
Antioxidant and antifungal potential of Pleurotus ostreatus and Agrocybe cylindracea basidiocarps and mycelia.
Ćilerdžić J, Stajić M, Vukojević J, Milovanović I, Muzgonja N. Ćilerdžić J, et al. Curr Pharm Biotechnol. 2015;16(2):179-86. doi: 10.2174/1389201015666141202152023. Curr Pharm Biotechnol. 2015. PMID: 25483715
Basidiocarps of Pleurotus ostreatus and Agrocybe cylindracea are characterized by high nutritional value and numerous medicinal activities, though bioactivities of their mycelia have not been sufficiently studied. The aim of the study was to evaluate antioxidant and ant …
Basidiocarps of Pleurotus ostreatus and Agrocybe cylindracea are characterized by high nutritional value and numerous medicinal activ …
Effect of cordycepin purified from Cordyceps militaris on Th1 and Th2 cytokines in mouse splenocytes.
Jeong MH, Seo MJ, Park JU, Kang BW, Kim KS, Lee JY, Kim GY, Kim JI, Choi YH, Kim KH, Jeong YK. Jeong MH, et al. J Microbiol Biotechnol. 2012 Aug;22(8):1161-4. doi: 10.4014/jmb.1203.03039. J Microbiol Biotechnol. 2012. PMID: 22713995 Free article.
Cordycepin was purified from a mushroom, Cordyceps militaris, and its effect on Th1 and Th2 cytokines was examined. The level of cytokine induction in mouse splenocytes was estimated after co-inoculation of purified cordycepin and LPS. ...
Cordycepin was purified from a mushroom, Cordyceps militaris, and its effect on Th1 and Th2 cytokines was examined. The level of cyto …
Easy and effective analytical method of carbendazim, dimethomorph, and fenoxanil from Protaetia brevitarsis seulensis using LC-MS/MS.
Baek S, Noh HH, Kim CJ, Son K, Lee HD, Kim L. Baek S, et al. PLoS One. 2021 Oct 14;16(10):e0258266. doi: 10.1371/journal.pone.0258266. eCollection 2021. PLoS One. 2021. PMID: 34648540 Free PMC article.
Traditionally in Korea, Protaetia brevitarsis seulensis (white-spotted flower chafer) has been used as a medicine, and recently has attracted increased attention due to its antithrombotic efficacy. Some of spent mushroom compost or fermented oak sawdust, a feedstock …
Traditionally in Korea, Protaetia brevitarsis seulensis (white-spotted flower chafer) has been used as a medicine, and recently has a …
Influence of Organic and Inorganic Compounds of Various Metals on the Synthesis of Polysaccharides by the Medicinal Mushroom Trametes versicolor.
Mustafin K, Suleimenova Z, Narmuratova Z, Akhmetsadykov N, Kalieva A. Mustafin K, et al. J AOAC Int. 2024 Jan 4;107(1):112-119. doi: 10.1093/jaoacint/qsad113. J AOAC Int. 2024. PMID: 37756685
These compounds have a high therapeutic potential and demonstrate immunomodulatory, antiviral, and antifungal activities. OBJECTIVE: The purpose of this study was to study the effect of various concentrations of metal citrates and sulphates on the content of exo- and endop …
These compounds have a high therapeutic potential and demonstrate immunomodulatory, antiviral, and antifungal activities. OBJECTIVE: …
Isolation of a small chitinase-like antifungal protein from Panax notoginseng (sanchi ginseng) roots.
Lam SK, Ng TB. Lam SK, et al. Int J Biochem Cell Biol. 2001 Mar;33(3):287-92. doi: 10.1016/s1357-2725(01)00002-4. Int J Biochem Cell Biol. 2001. PMID: 11311860
An antifungal protein, with a molecular weight of 15 kDa and an N-terminal sequence analogous to those of chitinases, was first isolated from the Chinese medicinal material Panax notoginseng, using cation exchange chromatography and affinity chromatography. The prot …
An antifungal protein, with a molecular weight of 15 kDa and an N-terminal sequence analogous to those of chitinases, was first isola …
Study on immunostimulating activity of macrophage treated with purified polysaccharides from liquid culture and fruiting body of Lentinus edodes.
Lee HH, Lee JS, Cho JY, Kim YE, Hong EK. Lee HH, et al. J Microbiol Biotechnol. 2009 Jun;19(6):566-72. doi: 10.4014/jmb.0809.541. J Microbiol Biotechnol. 2009. PMID: 19597314 Free article.
Lentinus edodes is a well-known edible and medicinal mushroom used in Oriental cultures. Recently, L. edodes has attracted a lot of attention owing to its antifungal activity, antibacterial activity, antiviral activity, hepatoprotective effect, antitumor acti …
Lentinus edodes is a well-known edible and medicinal mushroom used in Oriental cultures. Recently, L. edodes has attracted a l …
The chemical diversity, the attractant, anti-acetylcholinesterase, and antifungal activities of metabolites from biocontrol Trichoderma harzianum uncovered by OSMAC strategy.
Wang XY, Xu TT, Sun LJ, Cen RH, Su S, Yang XQ, Yang YB, Ding ZT. Wang XY, et al. Bioorg Chem. 2021 Sep;114:105148. doi: 10.1016/j.bioorg.2021.105148. Epub 2021 Jul 6. Bioorg Chem. 2021. PMID: 34246973
So 2, 3- dialkylchromone (7) had potential of chemical entrapment and killing of insects. Compounds 2, 3 and 7-11 showed antifungal activities against Aspergillus fumigates, and Trichoderma sp. from mushroom with MICs 300 muM. ...The material base of biocontrol in …
So 2, 3- dialkylchromone (7) had potential of chemical entrapment and killing of insects. Compounds 2, 3 and 7-11 showed antifungal a …
Combining the Elicitor Up-Regulated Production of Unusual Linear Diterpene-Derived Variants for an In-Depth Assessment of the Application Value and Risk of the Medicinal and Edible Basidiomycete Schizophyllum commune.
Wang Y, Cao F, Zhou L, Liu H, Gao H, Cui G, Niu C, Zhang P, Li D, Liu S, Jiang Y, Wu G. Wang Y, et al. Molecules. 2024 Jun 1;29(11):2608. doi: 10.3390/molecules29112608. Molecules. 2024. PMID: 38893484 Free PMC article.
To better assess the practical value and avoid potential risks of the traditionally medicinal and edible basidiomycete Schizophyllum commune, which may arise from undescribed metabolites, a combination of elicitors was introduced for the first time to discover products fro …
To better assess the practical value and avoid potential risks of the traditionally medicinal and edible basidiomycete Schizophyllum …
Anti-Allergic Effects of Dietary Caterpillar Mushroom Cordyceps militaris (Ascomycota) Derived from Eri Silkworm.
Kanno T, Kawasaki M, Tada R, Nakasone T, Okamatsu S, Tamura K, Miyaoka H, Adachi Y. Kanno T, et al. Int J Med Mushrooms. 2025;27(12):53-65. doi: 10.1615/IntJMedMushrooms.2025060071. Int J Med Mushrooms. 2025. PMID: 41135067
(C. militaris), an entomopathogenic fungus used in traditional East Asian medicine, contains bioactive compounds with potential immunomodulatory properties, including cordycepin and beta-glucans. ...
(C. militaris), an entomopathogenic fungus used in traditional East Asian medicine, contains bioactive compounds with potential immun …
Antimicrobial, Cytotoxic, Anti-Inflammatory, and Antioxidant Activity of Culinary Processed Shiitake Medicinal Mushroom (Lentinus edodes, Agaricomycetes) and Its Major Sulfur Sensory-Active Compound-Lenthionine.
Kupcova K, Stefanova I, Plavcova Z, Hosek J, Hrouzek P, Kubec R. Kupcova K, et al. Int J Med Mushrooms. 2018;20(2):165-175. doi: 10.1615/IntJMedMushrooms.2018025455. Int J Med Mushrooms. 2018. PMID: 29773008
The antimicrobial, cytotoxic, anti-inflammatory, and antioxidant properties of aqueous extracts of raw and culinary processed shiitake mushrooms were evaluated and compared with those of lenthionine (1,2,3,5,6-penta-thiepane), the principal aroma-bearing substance of the s …
The antimicrobial, cytotoxic, anti-inflammatory, and antioxidant properties of aqueous extracts of raw and culinary processed shiitake mu …
Cordyceps militaris mushroom and cordycepin inhibit RANKL-induced osteoclast differentiation.
Kim J, Lee H, Kang KS, Chun KH, Hwang GS. Kim J, et al. J Med Food. 2015 Apr;18(4):446-52. doi: 10.1089/jmf.2014.3215. Epub 2015 Mar 19. J Med Food. 2015. PMID: 25789604
Cordyceps militaris is a medicinal mushroom and its bioactive compound, cordycepin, is reported to have many pharmacological activities. ...
Cordyceps militaris is a medicinal mushroom and its bioactive compound, cordycepin, is reported to have many pharmacological a …
Allergic Bronchopulmonary Mycosis Due to Schizophyllum commune Treated Effectively with Voriconazole.
Ishiguro T, Kagiyama N, Kojima A, Yamada M, Nakamoto Y, Takaku Y, Shimizu Y, Kurashima K, Takayanagi N. Ishiguro T, et al. Intern Med. 2018 Sep 1;57(17):2553-2557. doi: 10.2169/internalmedicine.0668-17. Epub 2018 Mar 30. Intern Med. 2018. PMID: 29607966 Free PMC article.
We initially administered itraconazole unsuccessfully. Changing the antifungal agent to voriconazole resulted in improvement of the symptoms and chest imaging findings. ...
We initially administered itraconazole unsuccessfully. Changing the antifungal agent to voriconazole resulted in improvement of the s …
Evidence for Regulation of Cordycepin Biosynthesis by Transcription Factors Kruppel-Like Factor 4 and Retinoid X Receptor Alpha in Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).
Zhang H, Deng L, Luo S, Liu L, Yang G, Zhang Y, Gao B, Yang D, Wang X, Li S, Li X, Jiang Y, Lao W, Vriesekoop F. Zhang H, et al. Int J Med Mushrooms. 2024;26(10):19-40. doi: 10.1615/IntJMedMushrooms.2024054952. Int J Med Mushrooms. 2024. PMID: 39171629
Cordyceps militaris, Chinese traditional medicinal fungus, has many bioactive properties. Cordycepin (3'-deoxyadenosine) is a major bioactive component of C. militaris. ...
Cordyceps militaris, Chinese traditional medicinal fungus, has many bioactive properties. Cordycepin (3'-deoxyadenosine) is a major b …
Identification, biological characterization of Cladobotryum mycophilum and its control during the fruiting process of Lyophyllum decastes.
Wu T, Chen Y, Zhang W, Pu Z, Li J, Xu Y, Cheng J, Cai L, Hu K, Jin W. Wu T, et al. Arch Microbiol. 2025 Jan 29;207(2):48. doi: 10.1007/s00203-025-04245-y. Arch Microbiol. 2025. PMID: 39878829
Lyophyllum decastes is a type of edible and medicinal mushroom with high nutritional value. However, it can be infected by fungi during the fruiting process, which impairs the development of the industry. ...Koch's postulates showed that C. mycophilum could infect L …
Lyophyllum decastes is a type of edible and medicinal mushroom with high nutritional value. However, it can be infected by fun …
Drosophila alpha/beta mushroom body neurons form a branch-specific, long-term cellular memory trace after spaced olfactory conditioning.
Yu D, Akalal DB, Davis RL. Yu D, et al. Neuron. 2006 Dec 7;52(5):845-55. doi: 10.1016/j.neuron.2006.10.030. Neuron. 2006. PMID: 17145505 Free PMC article.
Functional optical imaging showed that odor or electric shock stimuli presented to the fly causes transient calcium influx into the two major axon branches of alpha/beta mushroom body (MB) neurons. One pairing of odor and electric shock stimuli or multiple, massed pairings …
Functional optical imaging showed that odor or electric shock stimuli presented to the fly causes transient calcium influx into the two majo …
Agrocybin, an antifungal peptide from the edible mushroom Agrocybe cylindracea.
Ngai PH, Zhao Z, Ng TB. Ngai PH, et al. Peptides. 2005 Feb;26(2):191-6. doi: 10.1016/j.peptides.2004.09.011. Peptides. 2005. PMID: 15629530
An antifungal peptide with a molecular mass of 9 kDa was isolated from fresh fruiting bodies of the mushroom Agrocybe cylindracea. ...Agrocybin exerted antifungal activity against several fungal species but lacked inhibitory activity against bacteria when tes …
An antifungal peptide with a molecular mass of 9 kDa was isolated from fresh fruiting bodies of the mushroom Agrocybe cylindra …
Enhanced production of polysaccharides and triterpenoids in Ganoderma lucidum fruit bodies on induction with signal transduction during the fruiting stage.
Ye L, Liu S, Xie F, Zhao L, Wu X. Ye L, et al. PLoS One. 2018 Apr 25;13(4):e0196287. doi: 10.1371/journal.pone.0196287. eCollection 2018. PLoS One. 2018. PMID: 29694432 Free PMC article.
Ganoderma lucidum is a medicinal mushroom that has been widely used in East Asia for the treatment of various diseases. ...
Ganoderma lucidum is a medicinal mushroom that has been widely used in East Asia for the treatment of various diseases. ...
Pleurotus sajor-caju can be used to synthesize silver nanoparticles with antifungal activity against Candida albicans.
Musa SF, Yeat TS, Kamal LZM, Tabana YM, Ahmed MA, El Ouweini A, Lim V, Keong LC, Sandai D. Musa SF, et al. J Sci Food Agric. 2018 Feb;98(3):1197-1207. doi: 10.1002/jsfa.8573. Epub 2017 Sep 21. J Sci Food Agric. 2018. PMID: 28746729
To assess its antifungal activity against Candida albicans, gene transcription and protein expression analyses were conducted for CaICL1 and its product, ICL, using real-time quantitative polymerase chain reaction and western blot, respectively. ...CONCLUSION: Our PSC-AgNP …
To assess its antifungal activity against Candida albicans, gene transcription and protein expression analyses were conducted for CaI …
Elicitor-Induced Modulation of Secondary Metabolites in Laetiporus Sulphureus and Flammulina Velutipes With Extraction Efficiency Evaluation in Artificial Digestive Juices.
Trepa M, Sułkowska-Ziaja K, Kała K, Krakowska A, Muszyńska B. Trepa M, et al. Chem Biodivers. 2025 Sep;22(9):e202500356. doi: 10.1002/cbdv.202500356. Epub 2025 May 12. Chem Biodivers. 2025. PMID: 40354814
Mushrooms are increasingly being studied for the development of new dietary supplements and drugs, which necessitates the analysis of their chemical profiles to assess their nutritional and health benefits. ...The high extraction of bioelements and selected metabolites int …
Mushrooms are increasingly being studied for the development of new dietary supplements and drugs, which necessitates the analysis of …
Hair dyes resorcinol and lawsone reduce production of melanin in melanoma cells by tyrosinase activity inhibition and decreasing tyrosinase and microphthalmia-associated transcription factor (MITF) expression.
Lee SM, Chen YS, Lin CC, Chen KH. Lee SM, et al. Int J Mol Sci. 2015 Jan 9;16(1):1495-508. doi: 10.3390/ijms16011495. Int J Mol Sci. 2015. PMID: 25584612 Free PMC article.
The results also confirmed that resorcinol and lawsone inhibit mushroom and cellular tyrosinase activities in vitro. Resorcinol and lawsone can also downregulate the protein levels of tyrosinase and microphthalmia-associated transcription factor (MITF) in B16-F10 cells. .. …
The results also confirmed that resorcinol and lawsone inhibit mushroom and cellular tyrosinase activities in vitro. Resorcinol and l …
Pleurostrin, an antifungal peptide from the oyster mushroom.
Chu KT, Xia L, Ng TB. Chu KT, et al. Peptides. 2005 Nov;26(11):2098-103. doi: 10.1016/j.peptides.2005.04.010. Epub 2005 Jun 6. Peptides. 2005. PMID: 15941607
A 7kDa peptide, with inhibitory activity on mycelial growth in the fungi Fusaerium oxysporum, Mycosphaerella arachidicola and Physalospora piricola, was isolated from fresh fruiting bodies of the oyster mushroom. The isolation procedure entailed extraction with an aqueous …
A 7kDa peptide, with inhibitory activity on mycelial growth in the fungi Fusaerium oxysporum, Mycosphaerella arachidicola and Physalospora p …
[Mucoid impaction of the bronchi caused by Schizophyllum commune which developed after discontinuation of itraconazole administration].
Ishiguro T, Takayanagi N, Harasaw K, Yoshii Y, Matsushita A, Yoneda K, Miyahara Y, Kagiyama N, Tokunaga D, Aoki F, Saito H, Ubukata M, Kurashima K, Yanagisawa T, Sugita Y, Kawabata Y, Kamei K. Ishiguro T, et al. Nihon Kokyuki Gakkai Zasshi. 2009 Apr;47(4):296-303. Nihon Kokyuki Gakkai Zasshi. 2009. PMID: 19455959 Review. Japanese.
Overview of the Biological Activities of a Methanol Extract from Wild Red Belt Conk, Fomitopsis pinicola (Agaricomycetes), Fruiting Bodies from Central Italy.
Angelini P, Tirillini B, Bistocchi G, Arcangeli A, Rubini A, Pellegrino RM, Fabiani R, Cruciani G, Venanzoni R, Rosignoli P. Angelini P, et al. Int J Med Mushrooms. 2018;20(11):1047-1063. doi: 10.1615/IntJMedMushrooms.2018028595. Int J Med Mushrooms. 2018. PMID: 30806229
Fomitopsis pinicola (Sw.) P. Karst. (Fomitopsidaceae) is a medicinal mushroom with a variety of healthy properties. In this study we tested the radical scavenging activity and antimicrobial and anticancer potential of methanol extracts of F. pinicola from central It …
Fomitopsis pinicola (Sw.) P. Karst. (Fomitopsidaceae) is a medicinal mushroom with a variety of healthy properties. In this st …
Exogenous Salicylic Acid (SA) Promotes the Accumulation of Biomass and Flavonoid Content in Phellinus igniarius (Agaricomycetes).
Shi L, Tan Y, Sun Z, Ren A, Zhu J, Zhao M. Shi L, et al. Int J Med Mushrooms. 2019;21(10):955-963. doi: 10.1615/IntJMedMushrooms.2019032557. Int J Med Mushrooms. 2019. PMID: 32450033
Phellinus igniarius is a very important, high-value medicinal fungus; flavonoids are one of its most important components. Methods to improve the content of flavonoids in Ph. igniarius deserve attention. ...The total flavonoid content could be increased up to 15.02 mug rut …
Phellinus igniarius is a very important, high-value medicinal fungus; flavonoids are one of its most important components. Methods to …
Exploring the Therapeutic Potential of Cordyceps Mushroom on SARS-CoV-2 Using Virtual Screening against M(pro) and In Vitro Validation of Cordycepin.
Baig MH, Turk A, Vishwakarma P, Jo YS, Dong JJ, Lee DH, Kim YG, Lee MK, Cho JY. Baig MH, et al. J Microbiol Biotechnol. 2025 Mar 26;35:e2411063. doi: 10.4014/jmb.2411.11063. J Microbiol Biotechnol. 2025. PMID: 40147924 Free PMC article.
Pathogenic coronavirus, including COVID-19, threatens human health, and there have been strong demands for efficient therapeutics. Cordyceps militaris is a medicinal mushroom that has long been used for immune enhancement, anticancer, and antiviral effects. ...
Pathogenic coronavirus, including COVID-19, threatens human health, and there have been strong demands for efficient therapeutics. Cordyceps …
Truffle's revenge: a pig-eating fungus.
Greer EL, Kowalski TJ, Cole ML, Miller DV, Baddour LM. Greer EL, et al. Cardiovasc Pathol. 2008 Sep-Oct;17(5):342-3. doi: 10.1016/j.carpath.2007.04.007. Epub 2007 Jun 20. Cardiovasc Pathol. 2008. PMID: 18402787
The fungus was identified as Hormographiella aspergillata, the asexual form of Coprinus cinereus, a common inky cap mushroom that grows in the lawn. She was treated with 6 weeks of liposomal amphotericin B and then switched to voriconazole for long-term (lifelong) suppress …
The fungus was identified as Hormographiella aspergillata, the asexual form of Coprinus cinereus, a common inky cap mushroom that gro …
A Novel Antibiotic Mechanism of l-Cyclopropylalanine Blocking the Biosynthetic Pathway of Essential Amino Acid l-Leucine.
Ma B, Shen J, Yindeeyoungyeon W, Ruan Y. Ma B, et al. Molecules. 2017 Dec 14;22(12):2224. doi: 10.3390/molecules22122224. Molecules. 2017. PMID: 29240717 Free PMC article.
The unusual amino acid l-cyclopropylalanine was isolated from the mushroom Amanita virgineoides after detection in an anti-fungal screening test. l-Cyclopropylalanine was found to exhibit broad-spectrum inhibition against fungi and bacteria. ...
The unusual amino acid l-cyclopropylalanine was isolated from the mushroom Amanita virgineoides after detection in an anti-fungal scr …
Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways.
Chen YY, Chou PY, Chien YC, Wu CH, Wu TS, Sheu MJ. Chen YY, et al. Phytomedicine. 2012 Jun 15;19(8-9):768-78. doi: 10.1016/j.phymed.2012.02.016. Epub 2012 Mar 29. Phytomedicine. 2012. PMID: 22464013
Antrodia cinnamomea (A. cinnamomea), a medicinal mushroom in Taiwan, has been shown antioxidant and anticancer activities. In this study, we first observed that ethanol extract of fruiting bodies of A. cinnamomea (EEAC) exerted a concentration-dependent inhibitory e …
Antrodia cinnamomea (A. cinnamomea), a medicinal mushroom in Taiwan, has been shown antioxidant and anticancer activities. In …
Ganoderma lucidum: a source for novel bioactive lectin.
U Girjal V, Neelagund S, Krishnappa M. U Girjal V, et al. Protein Pept Lett. 2011 Nov;18(11):1150-7. doi: 10.2174/092986611797200986. Protein Pept Lett. 2011. PMID: 21728991
Ganoderma lucidum is known for its high medicinal value, clinically used in treatment for various diseases. We have selected this mushroom for isolation of novel bioactive lectin. ...The hemagglutination activity was stable even in the presence of 10mM EDTA and othe …
Ganoderma lucidum is known for its high medicinal value, clinically used in treatment for various diseases. We have selected this …
Feasibility of the use of Lentinula edodes mycelium in terbinafine remediation.
Kryczyk-Poprawa A, Piotrowska J, Żmudzki P, Opoka W, Muszyńska B. Kryczyk-Poprawa A, et al. 3 Biotech. 2020 Apr;10(4):184. doi: 10.1007/s13205-020-02177-6. Epub 2020 Mar 29. 3 Biotech. 2020. PMID: 32257740 Free PMC article.
This study primarily aimed to investigate whether white-rot fungus (Lentinula edodes) can be utilized for the bioremediation of common antifungal agent terbinafine, which is mainly available in the market as powder or cream. ...
This study primarily aimed to investigate whether white-rot fungus (Lentinula edodes) can be utilized for the bioremediation of common an …
The methanolic extract of Cordyceps militaris (L.) Link fruiting body shows antioxidant, antibacterial, antifungal and antihuman tumor cell lines properties.
Reis FS, Barros L, Calhelha RC, Cirić A, van Griensven LJ, Soković M, Ferreira IC. Reis FS, et al. Food Chem Toxicol. 2013 Dec;62:91-8. doi: 10.1016/j.fct.2013.08.033. Epub 2013 Aug 27. Food Chem Toxicol. 2013. PMID: 23994083
Being Cordyceps militaris (L.) Link recognized as a medicinal and edible mushroom, this work intends to reveal new interesting bioactive molecules that could be isolated from this species. ...This extract also revealed strong antibacterial and antifungal prop …
Being Cordyceps militaris (L.) Link recognized as a medicinal and edible mushroom, this work intends to reveal new interesting …
Effects of Substrates on the Production of Fruiting Bodies and the Bioactive Components by Different Cordyceps militaris Strains (Ascomycetes).
Tao SX, Xue D, Lu ZH, Huang HL. Tao SX, et al. Int J Med Mushrooms. 2020;22(1):55-63. doi: 10.1615/IntJMedMushrooms.2019033257. Int J Med Mushrooms. 2020. PMID: 32463998
Cordyceps militaris is a type of food and medicinal species and is widely cultured in Asia. Substrate and strain are important factors for the production of fruiting bodies and bioactive components contents in fruiting bodies of C. militaris. ...
Cordyceps militaris is a type of food and medicinal species and is widely cultured in Asia. Substrate and strain are important factor …
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