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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1949 3
1950 16
1951 13
1952 12
1953 11
1954 6
1955 7
1956 3
1957 1
1958 7
1959 3
1960 2
1961 3
1962 4
1963 3
1964 5
1965 2
1966 8
1967 5
1968 6
1969 8
1970 8
1971 4
1972 3
1973 5
1974 13
1975 15
1976 18
1977 12
1978 13
1979 17
1980 11
1981 10
1982 21
1983 7
1984 12
1985 6
1986 8
1987 4
1988 7
1989 10
1990 9
1991 2
1992 5
1993 7
1994 6
1995 5
1996 11
1997 12
1998 6
1999 9
2000 10
2001 7
2002 8
2003 7
2004 3
2005 6
2006 9
2007 7
2008 10
2009 12
2010 3
2011 6
2012 12
2013 17
2014 5
2015 7
2016 10
2017 14
2018 11
2019 12
2020 16
2021 11
2022 14
2023 10
2024 14
2025 13
2026 11

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640 results

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Page 1
Severe megaloblastic anemia: Vitamin deficiency and other causes.
Socha DS, DeSouza SI, Flagg A, Sekeres M, Rogers HJ. Socha DS, et al. Cleve Clin J Med. 2020 Mar;87(3):153-164. doi: 10.3949/ccjm.87a.19072. Cleve Clin J Med. 2020. PMID: 32127439 Free article. Review.
Megaloblastic anemia causes macrocytic anemia from ineffective red blood cell production and intramedullary hemolysis. The most common causes are folate (vitamin B(9)) deficiency and cobalamin (vitamin B(12)) deficiency. Megaloblastic anemia …
Megaloblastic anemia causes macrocytic anemia from ineffective red blood cell production and intramedullary hemolysis. …
Megaloblastic Anemias: Nutritional and Other Causes.
Green R, Datta Mitra A. Green R, et al. Med Clin North Am. 2017 Mar;101(2):297-317. doi: 10.1016/j.mcna.2016.09.013. Epub 2016 Dec 14. Med Clin North Am. 2017. PMID: 28189172 Review.
Vitamin B(12) and folate deficiencies are major causes of megaloblastic anemia. Causes of B(12) deficiency include pernicious anemia, gastric surgery, intestinal disorders, dietary deficiency, and inherited disorders of B(12) transport or absorption. . …
Vitamin B(12) and folate deficiencies are major causes of megaloblastic anemia. Causes of B(12) deficiency include pern …
Vitamin B12 deficiency.
Green R, Miller JW. Green R, et al. Vitam Horm. 2022;119:405-439. doi: 10.1016/bs.vh.2022.02.003. Epub 2022 Mar 11. Vitam Horm. 2022. PMID: 35337628
Megaloblastic anemia results from a defect in thymidine and therefore DNA synthesis in rapidly dividing cells. ...B12 metabolism and deficiency is closely intertwined with folate, another B-vitamin. ...
Megaloblastic anemia results from a defect in thymidine and therefore DNA synthesis in rapidly dividing cells. ...B12 m …
Evaluation of macrocytosis.
Kaferle J, Strzoda CE. Kaferle J, et al. Am Fam Physician. 2009 Feb 1;79(3):203-8. Am Fam Physician. 2009. PMID: 19202968 Free article. Review.
The most common etiologies are alcoholism, vitamin B12 and folate deficiencies, and medications. History and physical examination, vitamin B12 level, reticulocyte count, and a peripheral smear are helpful in delineating the underlying cause of macrocytosis. W …
The most common etiologies are alcoholism, vitamin B12 and folate deficiencies, and medications. History and physical examinat …
Folic acid versus 5- methyl tetrahydrofolate supplementation in pregnancy.
Ferrazzi E, Tiso G, Di Martino D. Ferrazzi E, et al. Eur J Obstet Gynecol Reprod Biol. 2020 Oct;253:312-319. doi: 10.1016/j.ejogrb.2020.06.012. Epub 2020 Jun 13. Eur J Obstet Gynecol Reprod Biol. 2020. PMID: 32868164 Review.
Folate (vitamin B9) is widely accepted to protect against fetal neural tube defects. The main sources of dietary folate are folic acid-fortified foods and folic acid-containing dietary supplements. ...However, it can pose health risks in …
Folate (vitamin B9) is widely accepted to protect against fetal neural tube defects. The main sources of dietary folate are …
Vitamin B12 deficiency from the perspective of a practicing hematologist.
Green R. Green R. Blood. 2017 May 11;129(19):2603-2611. doi: 10.1182/blood-2016-10-569186. Epub 2017 Mar 30. Blood. 2017. PMID: 28360040 Free article. Review.
B(12) deficiency is the leading cause of megaloblastic anemia, and although more common in the elderly, can occur at any age. Clinical disease caused by B(12) deficiency usually connotes severe deficiency, resulting from a failure of the gastric or ileal phase of ph …
B(12) deficiency is the leading cause of megaloblastic anemia, and although more common in the elderly, can occur at any age. …
Homocysteine and Hyperhomocysteinaemia.
Zaric BL, Obradovic M, Bajic V, Haidara MA, Jovanovic M, Isenovic ER. Zaric BL, et al. Curr Med Chem. 2019;26(16):2948-2961. doi: 10.2174/0929867325666180313105949. Curr Med Chem. 2019. PMID: 29532755 Review.
The chemical reactions that are necessary for degradation of Hcy require the presence of folic acid, vitamins B6 and B12. Consequently, the level of the total Hcy in the serum is influenced by the presence or absence of these vitamins. An elevated level of th …
The chemical reactions that are necessary for degradation of Hcy require the presence of folic acid, vitamins B6 and B12 …
Excess Folic Acid and Vitamin B12 Deficiency: Clinical Implications?
Miller JW, Smith A, Troen AM, Mason JB, Jacques PF, Selhub J. Miller JW, et al. Food Nutr Bull. 2024 Jun;45(1_suppl):S67-S72. doi: 10.1177/03795721241229503. Food Nutr Bull. 2024. PMID: 38987872 Free PMC article. Review.
BACKGROUND: In the 1940s to 1950s, high-dose folic acid supplements (>5 mg/d) were used clinically to reverse the megaloblastic anemia of vitamin B12 deficiency caused by pernicious anemia. ...High-dose folic acid supplem …
BACKGROUND: In the 1940s to 1950s, high-dose folic acid supplements (>5 mg/d) were used clinically to reverse the megalo …
New Insights into Folate-Vitamin B(12) Interactions.
Castillo LF, Pelletier CM, Heyden KE, Field MS. Castillo LF, et al. Annu Rev Nutr. 2025 Aug;45(1):23-39. doi: 10.1146/annurev-nutr-120524-043056. Epub 2025 May 2. Annu Rev Nutr. 2025. PMID: 40315282 Free article. Review.
While folate deficiency is not common in the United States due to mandatory folic acid fortification, B12 deficiency is observed more frequently, particularly in certain subpopulations such as vegetarians/vegans and older adults. Fortification of the f …
While folate deficiency is not common in the United States due to mandatory folic acid fortification, B12 defici …
Anemia: Macrocytic Anemia.
Zwahlen D. Zwahlen D. FP Essent. 2023 Jul;530:17-21. FP Essent. 2023. PMID: 37390397
Megaloblastic anemia results from impaired DNA synthesis, leading to release of megaloblasts, which are large nucleated red blood cell precursors with chromatin that is not condensed. Vitamin B12 deficiency is the most common cause for megaloblastic …
Megaloblastic anemia results from impaired DNA synthesis, leading to release of megaloblasts, which are large nucleated red bl …
640 results