Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1994 2
1995 1
1996 1
1997 1
1998 1
1999 2
2000 3
2001 2
2002 4
2003 12
2004 6
2005 8
2006 9
2007 5
2008 10
2009 10
2010 7
2011 4
2012 5
2013 7
2014 7
2015 4
2016 3
2017 3
2018 2
2019 3
2020 6
2021 5
2023 1
2024 5
2025 2
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

117 results

Results by year

Filters applied: . Clear all
Page 1
5-Hydroxypyrroloindoline Affords Tryptathionine and 2,2'-bis-Indole Peptide Staples: Application to Melanotan-II.
Todorovic M, Blanc A, Wang Z, Lozada J, Froelich J, Zeisler J, Zhang C, Merkens H, Benard F, Perrin DM. Todorovic M, et al. Chemistry. 2024 Apr 2;30(19):e202304270. doi: 10.1002/chem.202304270. Epub 2024 Feb 15. Chemistry. 2024. PMID: 38285527
With peptides increasingly favored as drugs, natural product motifs, namely the tryptathionine staple, found in amatoxins and phallotoxins, and the 2,2'-bis-indole found in staurosporine represent unexplored staples for unnatural peptide macrocycles. We disclose the …
With peptides increasingly favored as drugs, natural product motifs, namely the tryptathionine staple, found in amatoxins and phallotoxins, …
Melanotan-induced priapism: a hard-earned tan.
Dreyer BA, Amer T, Fraser M. Dreyer BA, et al. BMJ Case Rep. 2019 Feb 21;12(2):e227644. doi: 10.1136/bcr-2018-227644. BMJ Case Rep. 2019. PMID: 30796078 Free PMC article. Review.
Melanocortin analogues, such as melanotan, are illegally used for artificial tanning. They have also been suggested as possible therapeutic agents in the treatment of erectile dysfunction. This case study presents a patient attending the accident and emergency department, …
Melanocortin analogues, such as melanotan, are illegally used for artificial tanning. They have also been suggested as possible thera …
Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity.
Cui J, Ding Y, Chen S, Zhu X, Wu Y, Zhang M, Zhao Y, Li TR, Sun LV, Zhao S, Zhuang Y, Jia W, Xue L, Han M, Xu T, Wu X. Cui J, et al. J Clin Invest. 2016 Sep 1;126(9):3192-206. doi: 10.1172/JCI85676. Epub 2016 Aug 8. J Clin Invest. 2016. PMID: 27500489 Free PMC article.
Consistent with this finding, intraventricular administration of melanotan-2, an analog of the POMC derivative alpha-MSH, suppressed adult obesity in Gpr45 mutants. ...
Consistent with this finding, intraventricular administration of melanotan-2, an analog of the POMC derivative alpha-MSH, supp …
Melanotan II: a possible cause of renal infarction: review of the literature and case report.
Peters B, Hadimeri H, Wahlberg R, Afghahi H. Peters B, et al. CEN Case Rep. 2020 May;9(2):159-161. doi: 10.1007/s13730-020-00447-z. Epub 2020 Jan 18. CEN Case Rep. 2020. PMID: 31953620 Free PMC article. Review.
Melanotan II inducing rhabdomyolysis and renal failure have been described previously. We present a review of Melanotan II and the possible effects of this drug on the kidneys by including a case of a renal infarction most likely attributed to Melanotan II. I …
Melanotan II inducing rhabdomyolysis and renal failure have been described previously. We present a review of Melanotan II and …
Eruptive Melanocytic Nevi: A Review.
Burian EA, Jemec GBE. Burian EA, et al. Am J Clin Dermatol. 2019 Oct;20(5):669-682. doi: 10.1007/s40257-019-00444-8. Am J Clin Dermatol. 2019. PMID: 31119650 Review.
The suspected causes were skin and other diseases (50%); immunosuppressive agents, chemotherapy or melanotan (41%); and miscellaneous, including idiopathic (9%). The clinical manifestations could largely be divided into two categories: EMN associated with skin diseases wer …
The suspected causes were skin and other diseases (50%); immunosuppressive agents, chemotherapy or melanotan (41%); and miscellaneous …
Melanotan II injection resulting in systemic toxicity and rhabdomyolysis.
Nelson ME, Bryant SM, Aks SE. Nelson ME, et al. Clin Toxicol (Phila). 2012 Dec;50(10):1169-73. doi: 10.3109/15563650.2012.740637. Epub 2012 Nov 5. Clin Toxicol (Phila). 2012. PMID: 23121206
Pertinent laboratory values were creatinine 2.25 mg/dL, CPK 1760 IU/L, troponin 0.23 ng/mL, WBC 19.1 k/muL. Urinalysis demonstrated 3 + blood with red cell casts but 0-2 RBC/hpf. ...The substance, which he injected, was analyzed via mass spectrometry and was confirm …
Pertinent laboratory values were creatinine 2.25 mg/dL, CPK 1760 IU/L, troponin 0.23 ng/mL, WBC 19.1 k/muL. Urinalysis demonstrated 3 …
Melanotan-II: Investigation of the inducer and facilitator effects on penile erection in anaesthetized rat.
Giuliano F, Clément P, Droupy S, Alexandre L, Bernabé J. Giuliano F, et al. Neuroscience. 2006;138(1):293-301. doi: 10.1016/j.neuroscience.2005.11.008. Epub 2005 Dec 19. Neuroscience. 2006. PMID: 16360286
Erectile events were of higher amplitude in rats treated with melanotan-II i.t. (0.2 microg) delivered at the L6-S1 level than in animals treated with the vehicle i.t. delivered. Erectile responses elicited by cavernous nerve stimulation were increased after i.v. …
Erectile events were of higher amplitude in rats treated with melanotan-II i.t. (0.2 microg) delivered at the L6-S1 level than …
Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet.
Breindahl T, Evans-Brown M, Hindersson P, McVeigh J, Bellis M, Stensballe A, Kimergård A. Breindahl T, et al. Drug Test Anal. 2015 Feb;7(2):164-72. doi: 10.1002/dta.1655. Epub 2014 Apr 25. Drug Test Anal. 2015. PMID: 24771717
Methods were based on liquid chromatography with ultra-violet detection (LC-UV) at wavelength 218 nm, and tandem mass spectrometric detection (MS/MS) after collision-induced fragmentation of the double charged [M+2H](2+) precursor ion (m/z 513). Identification of melano …
Methods were based on liquid chromatography with ultra-violet detection (LC-UV) at wavelength 218 nm, and tandem mass spectrometric detectio …
Effect of MELANOTAN, [Nle(4), D-Phe(7)]-alpha-MSH, on melanin synthesis in humans with MC1R variant alleles.
Fitzgerald LM, Fryer JL, Dwyer T, Humphrey SM. Fitzgerald LM, et al. Peptides. 2006 Feb;27(2):388-94. doi: 10.1016/j.peptides.2004.12.038. Epub 2005 Nov 15. Peptides. 2006. PMID: 16293341 Clinical Trial.
MELANOTAN (NDP-MSH) binds the MC1 receptor to significantly increase the eumelanin content of human skin cells. In this study of 77 Caucasian individuals, we investigated the effects of MELANOTAN in individuals with variant MC1R genotypes, as it has been suggested t …
MELANOTAN (NDP-MSH) binds the MC1 receptor to significantly increase the eumelanin content of human skin cells. In this study of 77 C …
Melanotan II, a melanocortin agonist, partially rescues the impaired thermogenic capacity of pituitary adenylate cyclase-activating polypeptide deficient mice.
McMillan TR, Forster MAM, Short LI, Rudecki AP, Cline DL, Gray SL. McMillan TR, et al. Exp Physiol. 2021 Feb;106(2):427-437. doi: 10.1113/EP088838. Epub 2020 Dec 17. Exp Physiol. 2021. PMID: 33332767 Free article.
Can chronic treatment of pituitary adenylate cyclase-activating polypeptide (PACAP) deficient mice with the melanocortin agonist melanotan II during cold acclimation rescue the impaired thermogenic capacity previously observed in PACAP deficient mice? ...To assess this, fe …
Can chronic treatment of pituitary adenylate cyclase-activating polypeptide (PACAP) deficient mice with the melanocortin agonist melanota …
117 results