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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 3
1981 1
1982 4
1983 3
1984 7
1985 7
1986 2
1987 1
1988 4
1989 7
1990 16
1991 6
1992 1
1993 4
1994 3
1995 3
1996 4
1997 4
1998 7
1999 5
2000 4
2001 4
2002 1
2005 6
2006 6
2007 6
2008 6
2009 13
2010 8
2011 13
2012 16
2013 16
2014 17
2015 16
2016 20
2017 16
2018 7
2019 13
2020 17
2021 23
2022 16
2023 13
2024 8

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330 results

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Page 1
Hypnotic and Melatonin/Melatonin-Receptor Agonist Treatment in Bipolar Disorder: A Systematic Review and Meta-Analysis.
McGowan NM, Kim DS, de Andres Crespo M, Bisdounis L, Kyle SD, Saunders KEA. McGowan NM, et al. CNS Drugs. 2022 Apr;36(4):345-363. doi: 10.1007/s40263-022-00911-7. Epub 2022 Mar 19. CNS Drugs. 2022. PMID: 35305257
BACKGROUND: Bipolar disorder (BD) is a chronic relapsing-remitting psychiatric disorder. ...Few studies assessed sleep-related symptoms, and none quantitatively examined endogenous melatonin patterns or other circadian rhythms. Melatonin may be a promising ca …
BACKGROUND: Bipolar disorder (BD) is a chronic relapsing-remitting psychiatric disorder. ...Few studies assessed sleep-related sympto …
Circadian rhythm in bipolar disorder: A review of the literature.
Takaesu Y. Takaesu Y. Psychiatry Clin Neurosci. 2018 Sep;72(9):673-682. doi: 10.1111/pcn.12688. Epub 2018 Jul 4. Psychiatry Clin Neurosci. 2018. PMID: 29869403 Free article. Review.
Sleep disturbances and circadian rhythm dysfunction have been widely demonstrated in patients with bipolar disorder (BD). Irregularity of the sleep-wake rhythm, eveningness chronotype, abnormality of melatonin secretion, vulnerability of clock genes, and the irregul …
Sleep disturbances and circadian rhythm dysfunction have been widely demonstrated in patients with bipolar disorder (BD). Irregularit …
Role of Melatonin in the Management of Sleep and Circadian Disorders in the Context of Psychiatric Illness.
Moon E, Kim K, Partonen T, Linnaranta O. Moon E, et al. Curr Psychiatry Rep. 2022 Nov;24(11):623-634. doi: 10.1007/s11920-022-01369-6. Epub 2022 Oct 13. Curr Psychiatry Rep. 2022. PMID: 36227449 Free PMC article. Review.
On the other hand, melatonin dysregulation in bipolar disorder may be more dynamic and caused by light-sensitive melatonin suppression and delayed melatonin secretion. ...Based on the partly fragmentary information, we propose testing efficacy in disor …
On the other hand, melatonin dysregulation in bipolar disorder may be more dynamic and caused by light-sensitive melatonin
Melatonin and Melatonin Agonists as Adjunctive Treatments in Bipolar Disorders.
Geoffroy PA, Etain B, Franchi JA, Bellivier F, Ritter P. Geoffroy PA, et al. Curr Pharm Des. 2015;21(23):3352-8. doi: 10.2174/1381612821666150619093448. Curr Pharm Des. 2015. PMID: 26088111 Review.
Bipolar disorders (BD) present with abnormalities of circadian rhythmicity and sleep homeostasis, even during phases of remission. ...In order to evaluate the efficacy of melatonin among patients with BD, this comprehensive review emphasizes the abnormal melatoni
Bipolar disorders (BD) present with abnormalities of circadian rhythmicity and sleep homeostasis, even during phases of remission. ..
Melatonin Receptor Gene Polymorphism in Bipolar-I Disorder.
Mulayim E, Karababa İF, Akbaş H, Bayazıt H, Selek S. Mulayim E, et al. Arch Med Res. 2021 Jul;52(5):523-528. doi: 10.1016/j.arcmed.2021.01.002. Epub 2021 Feb 2. Arch Med Res. 2021. PMID: 33546869
Melatonin is a main regulatory hormone for the circadian rhythm. Certain studies have shown the relationship of melatonin receptor gene polymorphism with psychiatric diseases. In this study, it was aimed to investigate the relationship between BD-I and -184T>C (r
Melatonin is a main regulatory hormone for the circadian rhythm. Certain studies have shown the relationship of melatonin rece
Melatonin secretion patterns are associated with cognitive vulnerability and brain structure in bipolar depression.
Melloni EMT, Paolini M, Dallaspezia S, Lorenzi C, Poletti S, d'Orsi G, Yoshiike T, Zanardi R, Colombo C, Benedetti F. Melloni EMT, et al. Chronobiol Int. 2023 Sep 2;40(9):1279-1290. doi: 10.1080/07420528.2023.2262572. Epub 2023 Oct 9. Chronobiol Int. 2023. PMID: 37781880
Circadian rhythm disruption is a core symptom of bipolar disorder (BD), also reflected in altered patterns of melatonin release. ...Our findings emphasized the role of melatonin secretion role as a biological marker of circadian synchronization in bipolar
Circadian rhythm disruption is a core symptom of bipolar disorder (BD), also reflected in altered patterns of melatonin releas …
The Role of Tryptophan Metabolites in Neuropsychiatric Disorders.
Davidson M, Rashidi N, Nurgali K, Apostolopoulos V. Davidson M, et al. Int J Mol Sci. 2022 Sep 1;23(17):9968. doi: 10.3390/ijms23179968. Int J Mol Sci. 2022. PMID: 36077360 Free PMC article. Review.
In recent decades, neuropsychiatric disorders such as major depressive disorder, schizophrenia, bipolar, etc., have become a global health concern, causing various detrimental influences on patients. ...Furthermore, other biologically active components, such as serotonin, …
In recent decades, neuropsychiatric disorders such as major depressive disorder, schizophrenia, bipolar, etc., have become a global h …
Methylation of melatonin receptors in patients with unipolar and bipolar depression.
Lesicka M, Dmitrzak-Weglarz M, Jablonska E, Wieczorek E, Kapelski P, Szczepankiewicz A, Pawlak J, Reszka E. Lesicka M, et al. Mech Ageing Dev. 2023 Apr;211:111776. doi: 10.1016/j.mad.2023.111776. Epub 2023 Jan 24. Mech Ageing Dev. 2023. PMID: 36706965
Disturbances of melatonin secretion alter the circadian rhythm and sleep-wake cycle, which is observed among patients with depression. Melatonin acts via melatonin receptors MT1 and MT2, which are present in many tissues, including peripheral blood mononuclea …
Disturbances of melatonin secretion alter the circadian rhythm and sleep-wake cycle, which is observed among patients with depression …
Melatonin receptor agonists-ramelteon and melatonin-for bipolar disorder: a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials.
Kishi T, Nomura I, Sakuma K, Kitajima T, Mishima K, Iwata N. Kishi T, et al. Neuropsychiatr Dis Treat. 2019 May 30;15:1479-1486. doi: 10.2147/NDT.S198899. eCollection 2019. Neuropsychiatr Dis Treat. 2019. PMID: 31239683 Free PMC article.
Objective: This study was a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials, investigating the efficacy and tolerability/safety of melatonin receptor agonists, such as ramelteon and melatonin, for patients with bipolar
Objective: This study was a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials, investigating the ef …
Melatonin suppression by melanopsin-weighted light in patients with bipolar I disorder compared to healthy controls.
Ritter P, Wieland F, Skene DJ, Pfennig A, Weiss M, Bauer M, Severus E, Güldner H, Sauer C, Soltmann B, Neumann S. Ritter P, et al. J Psychiatry Neurosci. 2020 Mar 1;45(2):79-87. doi: 10.1503/jpn.190005. J Psychiatry Neurosci. 2020. PMID: 32096617 Free PMC article.
Increased suppression of melatonin by light (supersensitivity) in patients with bipolar disorder has been postulated as an endophenotype by several studies. ...CONCLUSION: Despite using a large cohort and highly controlled laboratory conditions, we found no differen …
Increased suppression of melatonin by light (supersensitivity) in patients with bipolar disorder has been postulated as an end …
330 results