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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 3
1981 1
1982 4
1983 3
1984 7
1985 7
1986 2
1987 1
1988 4
1989 7
1990 16
1991 6
1992 1
1993 4
1994 3
1995 3
1996 4
1997 4
1998 7
1999 5
2000 4
2001 4
2002 1
2005 6
2006 6
2007 6
2008 6
2009 13
2010 8
2011 13
2012 16
2013 16
2014 17
2015 16
2016 20
2017 16
2018 7
2019 13
2020 8
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271 results
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Page 1
Melatonin receptor agonists-ramelteon and melatonin-for bipolar disorder: a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials.
Kishi T, Nomura I, Sakuma K, Kitajima T, Mishima K, Iwata N. Kishi T, et al. Neuropsychiatr Dis Treat. 2019 May 30;15:1479-1486. doi: 10.2147/NDT.S198899. eCollection 2019. Neuropsychiatr Dis Treat. 2019. PMID: 31239683 Free PMC article.
Objective: This study was a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials, investigating the efficacy and tolerability/safety of melatonin receptor agonists, such as ramelteon and melatonin, for patients with bipolar
Objective: This study was a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials, investigating the ef …
Melatonin and Melatonin Agonists as Adjunctive Treatments in Bipolar Disorders.
Geoffroy PA, Etain B, Franchi JA, Bellivier F, Ritter P. Geoffroy PA, et al. Curr Pharm Des. 2015;21(23):3352-8. doi: 10.2174/1381612821666150619093448. Curr Pharm Des. 2015. PMID: 26088111 Review.
Bipolar disorders (BD) present with abnormalities of circadian rhythmicity and sleep homeostasis, even during phases of remission. ...In order to evaluate the efficacy of melatonin among patients with BD, this comprehensive review emphasizes the abnormal melatoni
Bipolar disorders (BD) present with abnormalities of circadian rhythmicity and sleep homeostasis, even during phases of remission. ..
Circadian rhythm in bipolar disorder: A review of the literature.
Takaesu Y. Takaesu Y. Psychiatry Clin Neurosci. 2018 Sep;72(9):673-682. doi: 10.1111/pcn.12688. Epub 2018 Jul 4. Psychiatry Clin Neurosci. 2018. PMID: 29869403 Free article. Review.
Sleep disturbances and circadian rhythm dysfunction have been widely demonstrated in patients with bipolar disorder (BD). Irregularity of the sleep-wake rhythm, eveningness chronotype, abnormality of melatonin secretion, vulnerability of clock genes, and the irregul …
Sleep disturbances and circadian rhythm dysfunction have been widely demonstrated in patients with bipolar disorder (BD). Irregularit …
Melatonin suppression by melanopsin-weighted light in patients with bipolar I disorder compared to healthy controls.
Ritter P, Wieland F, Skene DJ, Pfennig A, Weiss M, Bauer M, Severus E, Güldner H, Sauer C, Soltmann B, Neumann S. Ritter P, et al. J Psychiatry Neurosci. 2019 Sep 11;44(6):190005. doi: 10.1503/jpn.190005. Online ahead of print. J Psychiatry Neurosci. 2019. PMID: 31509363 Free article.
METHODS: Melatonin suppression was assessed in euthymic patients with bipolar I disorder and healthy controls by exposure to monochromatic blue light (λmax = 475 nm; photon density = 1.6 × 1013 photons/cm2/s) for 30 minutes at 2300 h, administered via a ganzf …
METHODS: Melatonin suppression was assessed in euthymic patients with bipolar I disorder and healthy controls by exposure to m …
Melatonin as a treatment for mood disorders: a systematic review.
De Crescenzo F, Lennox A, Gibson JC, Cordey JH, Stockton S, Cowen PJ, Quested DJ. De Crescenzo F, et al. Acta Psychiatr Scand. 2017 Dec;136(6):549-558. doi: 10.1111/acps.12755. Epub 2017 Jun 14. Acta Psychiatr Scand. 2017. PMID: 28612993 Review.
RESULTS: Eight clinical trials were included; one study in bipolar, three in unipolar depression and four in seasonal affective disorder. We have only a small study on patients with bipolar disorder, while we have more studies testing melatonin as an augmenta …
RESULTS: Eight clinical trials were included; one study in bipolar, three in unipolar depression and four in seasonal affective disor …
Salivary melatonin onset in youth at familial risk for bipolar disorder.
Ghaziuddin N, Shamseddeen W, Bertram H, McInnis M, Wilcox HC, Mitchell PB, Fullerton JM, Roberts GMP, Glowinski AL, Kamali M, Stapp E, Hulvershorn LA, Nurnberger J, Armitage R; Bipolar High Risk Research Group. Ghaziuddin N, et al. Psychiatry Res. 2019 Apr;274:49-57. doi: 10.1016/j.psychres.2019.02.013. Epub 2019 Feb 6. Psychiatry Res. 2019. PMID: 30780062
Melatonin secretion and polysomnography (PSG) were compared among a group of healthy adolescents who were at high familial risk for bipolar disorder (HR) and a second group at low familial risk (LR). ...Red Light Melatonin onset (RLMO) was defined as saliva
Melatonin secretion and polysomnography (PSG) were compared among a group of healthy adolescents who were at high familial risk for
The use of melatonin in adult psychiatric disorders: Expert recommendations by the French institute of medical research on sleep (SFRMS).
Geoffroy PA, Micoulaud Franchi JA, Lopez R, Schroder CM; membres du consensus Mélatonine SFRMS. Geoffroy PA, et al. Encephale. 2019 Nov;45(5):413-423. doi: 10.1016/j.encep.2019.04.068. Epub 2019 Jun 24. Encephale. 2019. PMID: 31248601
Melatonin is a hormone secreted by the pineal gland at night. This hormone has many physiological functions, the main one being to synchronise individuals' biological rhythms. ...During acute phases, melatonin could be used as an adjuvant treatment when there are in
Melatonin is a hormone secreted by the pineal gland at night. This hormone has many physiological functions, the main one being to sy
Investigating the relationship between melatonin levels, melatonin system, microbiota composition and bipolar disorder psychopathology across the different phases of the disease.
Manchia M, Squassina A, Pisanu C, Congiu D, Garzilli M, Guiso B, Suprani F, Paribello P, Pulcinelli V, Iaselli MN, Pinna F, Valtorta F, Carpiniello B, Comai S. Manchia M, et al. Int J Bipolar Disord. 2019 Dec 9;7(1):27. doi: 10.1186/s40345-019-0163-y. Int J Bipolar Disord. 2019. PMID: 31814040 Free PMC article.
BACKGROUND: Bipolar disorder (BD) is characterized by recurrent episodes of depression and mania/hypomania alternating with intervals of well-being. The neurobiological underpinnings of BD are still veiled although there is evidence pointing to a malfunction of the circadi …
BACKGROUND: Bipolar disorder (BD) is characterized by recurrent episodes of depression and mania/hypomania alternating with intervals …
Chronotype and circadian rhythm in bipolar disorder: A systematic review.
Melo MCA, Abreu RLC, Linhares Neto VB, de Bruin PFC, de Bruin VMS. Melo MCA, et al. Sleep Med Rev. 2017 Aug;34:46-58. doi: 10.1016/j.smrv.2016.06.007. Epub 2016 Jul 1. Sleep Med Rev. 2017. PMID: 27524206 Review.
Despite a complex relationship between mood, sleep and rhythm, the impact of circadian disruptions on bipolar disorder (BD) has not been clarified. ...Daily profiles of melatonin levels and cortisol indicated a delayed phase. Depression was more frequently associate …
Despite a complex relationship between mood, sleep and rhythm, the impact of circadian disruptions on bipolar disorder (BD) has not b …
A model of the mitochondrial basis of bipolar disorder.
Morris G, Walder K, McGee SL, Dean OM, Tye SJ, Maes M, Berk M. Morris G, et al. Neurosci Biobehav Rev. 2017 Mar;74(Pt A):1-20. doi: 10.1016/j.neubiorev.2017.01.014. Epub 2017 Jan 14. Neurosci Biobehav Rev. 2017. PMID: 28093238 Review.
BACKGROUND: Bipolar disorder phenomenologically is a biphasic disorder of energy availability; increased in mania and decreased in depression. ...Uric acid and melatonin are also differentially elevated in bipolar mania and both molecules stimulate the produc …
BACKGROUND: Bipolar disorder phenomenologically is a biphasic disorder of energy availability; increased in mania and decreased in de …
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