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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1976 1
1977 2
1978 2
1979 1
1980 1
1982 5
1983 2
1984 2
1985 10
1986 11
1987 3
1988 5
1989 5
1990 11
1991 14
1992 11
1993 24
1994 10
1995 35
1996 52
1997 57
1998 73
1999 88
2000 74
2001 88
2002 72
2003 78
2004 69
2005 114
2006 123
2007 110
2008 109
2009 144
2010 131
2011 142
2012 161
2013 157
2014 186
2015 175
2016 178
2017 169
2018 175
2019 214
2020 244
2021 234
2022 238
2023 247
2024 244
2025 309
2026 207

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4,342 results

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Page 1
Melatonin in sleep disorders.
Poza JJ, Pujol M, Ortega-Albás JJ, Romero O; Insomnia Study Group of the Spanish Sleep Society (SES). Poza JJ, et al. Neurologia (Engl Ed). 2022 Sep;37(7):575-585. doi: 10.1016/j.nrleng.2018.08.004. Epub 2020 Sep 18. Neurologia (Engl Ed). 2022. PMID: 36064286 Free article. Review.
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be administered orally, which has led to interest in its use as a treatment for insomnia. Moreover, as production of the hormone decreases with a
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be ad
Melatonin in sleep disorders.
Poza JJ, Pujol M, Ortega-Albás JJ, Romero O; en representación del Grupo de estudio de insomnio de la Sociedad Española de Sueño (SES). Poza JJ, et al. Neurologia (Engl Ed). 2022 Sep;37(7):575-585. doi: 10.1016/j.nrl.2018.08.002. Epub 2018 Nov 19. Neurologia (Engl Ed). 2022. PMID: 30466801 Free article. Review. English, Spanish.
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be administered orally, which has led to interest in its use as a treatment for insomnia. Moreover, as production of the hormone decreases with a
Melatonin is the main hormone involved in the control of the sleep-wake cycle. It is easily synthesisable and can be ad
Meta-analysis: melatonin for the treatment of primary sleep disorders.
Ferracioli-Oda E, Qawasmi A, Bloch MH. Ferracioli-Oda E, et al. PLoS One. 2013 May 17;8(5):e63773. doi: 10.1371/journal.pone.0063773. Print 2013. PLoS One. 2013. PMID: 23691095 Free PMC article.
STUDY OBJECTIVES: To investigate the efficacy of melatonin compared to placebo in improving sleep parameters in patients with primary sleep disorders. DESIGN: PubMed was searched for randomized, placebo-controlled trials examining the effects of mel
STUDY OBJECTIVES: To investigate the efficacy of melatonin compared to placebo in improving sleep parameters in patients with …
A review of sleep disorders and melatonin.
Xie Z, Chen F, Li WA, Geng X, Li C, Meng X, Feng Y, Liu W, Yu F. Xie Z, et al. Neurol Res. 2017 Jun;39(6):559-565. doi: 10.1080/01616412.2017.1315864. Epub 2017 May 1. Neurol Res. 2017. PMID: 28460563 Free article. Review.
It is centrally involved in anti-oxidation, circadian rhythmicity maintenance, sleep regulation and neuronal survival. This narrative review aims to provide a comprehensive overview of various therapeutic functions of melatonin in insomnia, sleep-related brea …
It is centrally involved in anti-oxidation, circadian rhythmicity maintenance, sleep regulation and neuronal survival. This narrative …
Melatonin for sleep disorders in people with autism: Systematic review and meta-analysis.
Nogueira HA, de Castro CT, da Silva DCG, Pereira M. Nogueira HA, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Apr 20;123:110695. doi: 10.1016/j.pnpbp.2022.110695. Epub 2022 Dec 28. Prog Neuropsychopharmacol Biol Psychiatry. 2023. PMID: 36584862
Melatonin is a potential therapeutic intervention for improving sleep quality in people with autistic spectrum disorder (ASD). ...Melatonin has possible efficacy over total time, latency, and efficiency sleep parameters....
Melatonin is a potential therapeutic intervention for improving sleep quality in people with autistic spectrum disorder (ASD).
Treatment of Circadian Rhythm Sleep-Wake Disorders.
Sun SY, Chen GH. Sun SY, et al. Curr Neuropharmacol. 2022;20(6):1022-1034. doi: 10.2174/1570159X19666210907122933. Curr Neuropharmacol. 2022. PMID: 34493186 Free PMC article. Review.
Circadian rhythm sleep-wake disorders (CRSWDs) are a distinct class of sleep disorders caused by alterations to the circadian time-keeping system, its entrainment mechanisms, or a mismatch between the endogenous circadian rhythm and the external …
Circadian rhythm sleep-wake disorders (CRSWDs) are a distinct class of sleep disorders caused by alterati …
Sleep Disorders.
K Pavlova M, Latreille V. K Pavlova M, et al. Am J Med. 2019 Mar;132(3):292-299. doi: 10.1016/j.amjmed.2018.09.021. Epub 2018 Oct 4. Am J Med. 2019. PMID: 30292731 Review.
Sleep disorders are frequent and can have serious consequences on patients' health and quality of life. ...We review the main diagnostic features of 6 major sleep disorders (insomnia, circadian rhythm disorders, sleep-disordered breathing
Sleep disorders are frequent and can have serious consequences on patients' health and quality of life. ...We review the main
Circadian rhythms and disorders of the timing of sleep.
Meyer N, Harvey AG, Lockley SW, Dijk DJ. Meyer N, et al. Lancet. 2022 Sep 24;400(10357):1061-1078. doi: 10.1016/S0140-6736(22)00877-7. Epub 2022 Sep 14. Lancet. 2022. PMID: 36115370 Review.
Characterised by undesirable or irregular timing of sleep and wakefulness, in this Series paper we critically examine the existing categories of circadian rhythm sleep-wake disorders and the role of the circadian system in their development. We emphasi …
Characterised by undesirable or irregular timing of sleep and wakefulness, in this Series paper we critically examine the existing ca …
Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials.
Fatemeh G, Sajjad M, Niloufar R, Neda S, Leila S, Khadijeh M. Fatemeh G, et al. J Neurol. 2022 Jan;269(1):205-216. doi: 10.1007/s00415-020-10381-w. Epub 2021 Jan 8. J Neurol. 2022. PMID: 33417003
Subgroup analysis based on health status revealed melatonin intervention in subjects with Respiratory diseases (WMD: - 2.20; 95% CI - 2.97, - 1.44, p = 0.000), Metabolic disorders (WMD: - 2.74; 95% CI - 3.48, - 2.00, p = 0.000) and sleep disorders (WMD …
Subgroup analysis based on health status revealed melatonin intervention in subjects with Respiratory diseases (WMD: - 2.20; 95% CI - …
Circadian Rhythm Sleep-Wake Disorders in Older Adults.
Kim JH, Elkhadem AR, Duffy JF. Kim JH, et al. Sleep Med Clin. 2022 Jun;17(2):241-252. doi: 10.1016/j.jsmc.2022.02.003. Sleep Med Clin. 2022. PMID: 35659077 Free PMC article. Review.
This mismatch between the desired timing of sleep and the ability to fall asleep and remain asleep is a hallmark of a class of sleep disorders called the circadian rhythm sleep-wake disorders. In this updated article, we discuss typical c …
This mismatch between the desired timing of sleep and the ability to fall asleep and remain asleep is a hallmark of a class of sle
4,342 results