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1998 1
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2002 1
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2004 4
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2006 6
2008 7
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2010 9
2011 18
2012 15
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2015 26
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2018 30
2019 33
2020 15
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Melissa officinalis L: A Review Study With an Antioxidant Prospective.
Miraj S, Rafieian-Kopaei, Kiani S. Miraj S, et al. J Evid Based Complementary Altern Med. 2017 Jul;22(3):385-394. doi: 10.1177/2156587216663433. Epub 2016 Sep 11. J Evid Based Complementary Altern Med. 2017. PMID: 27620926 Free PMC article. Review.
The search terms used were " Melissa officinalis L," "antioxidant properties," oxidative stress," "oxidative damage", "ROS." ...Many studies confirmed the antioxidative effects of Melissa officinalis; thus, its effect in preventing and treating oxidative stress-related diseases might be reliable....
The search terms used were " Melissa officinalis L," "antioxidant properties," oxidative stress," "oxidative damage", " …
The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina.
Haybar H, Javid AZ, Haghighizadeh MH, Valizadeh E, Mohaghegh SM, Mohammadzadeh A. Haybar H, et al. Clin Nutr ESPEN. 2018 Aug;26:47-52. doi: 10.1016/j.clnesp.2018.04.015. Epub 2018 May 19. Clin Nutr ESPEN. 2018. PMID: 29908682 Clinical Trial.
BACKGROUND: Despite advances in the treatment of cardiovascular diseases in recent decades, patients experience high levels of depression, anxiety, stress, and insomnia. Since the calming effect of Melissa officinalis (MO) has been known, this study aimed to determine the effects of MO supplementation on depression, anxiety, stress, and sleep disturbances in patients with chronic stable angina (CSA). ...
BACKGROUND: Despite advances in the treatment of cardiovascular diseases in recent decades, patients experience high levels of depression, a …
The effects of Melissa officinalis (lemon balm) in chronic stable angina on serum biomarkers of oxidative stress, inflammation and lipid profile.
Javid AZ, Haybar H, Dehghan P, Haghighizadeh MH, Mohaghegh SM, Ravanbakhsh M, Mohammadzadeh A. Javid AZ, et al. Asia Pac J Clin Nutr. 2018;27(4):785-791. doi: 10.6133/apjcn.022018.01. Asia Pac J Clin Nutr. 2018. PMID: 30045422 Free article. Clinical Trial.
Oxidative stress and inflammation play a substantial role in pathogenesis and progression of CAD. The aim of this study was to investigate the effects of oral administration of powdered Melissa officinalis (MO) on biomarkers of oxidative stress, inflammation, and lipid profile in patients with CSA. ...Anthropometric indices, biomarkers of oxidative stress, inflammation, and lipid profile were evaluated at baseline and post-intervention. ...
Oxidative stress and inflammation play a substantial role in pathogenesis and progression of CAD. The aim of this study was to invest …
Melissa officinalis Acidic Fraction Protects Cultured Cerebellar Granule Neurons Against Beta Amyloid-Induced Apoptosis and Oxidative Stress.
Soodi M, Dashti A, Hajimehdipoor H, Akbari S, Ataei N. Soodi M, et al. Cell J. 2017 Winter;18(4):556-564. doi: 10.22074/cellj.2016.4722. Epub 2016 Sep 26. Cell J. 2017. PMID: 28042540 Free PMC article.
Melissa officinalis (M. officinalis) is a medicinal plant from the Lamiaceae family that has neuroprotective activity. In the present study we have investigated the protective effect of the acidic fraction of M. officinalis on Aβ-induced oxidative stress and apoptosis in cultured cerebellar granule neurons (CGN). ...Preincubation with the acidic fraction of M. officinalis ameliorated these factors and decreased the number of apoptotic cells. ...
Melissa officinalis (M. officinalis) is a medicinal plant from the Lamiaceae family that has neuroprotective activity.
Melissa officinalis L. hydro-alcoholic extract inhibits anxiety and depression through prevention of central oxidative stress and apoptosis.
Ghazizadeh J, Hamedeyazdan S, Torbati M, Farajdokht F, Fakhari A, Mahmoudi J, Araj-Khodaei M, Sadigh-Eteghad S. Ghazizadeh J, et al. Exp Physiol. 2020 Jan 31. doi: 10.1113/EP088254. Online ahead of print. Exp Physiol. 2020. PMID: 32003913
How does an extract of Melissa officinalis L. ameliorate anxiety- and depressive-like behaviour of mice? What is the main finding and its importance? ...ABSTRACT: This study evaluated the effects of a hydro-alcoholic extract of Melissa officinalis (HAEMO) on anxiety- and depressive-like behaviours, oxidative stress and apoptosis markers in restraint stress-exposed mice. ...
How does an extract of Melissa officinalis L. ameliorate anxiety- and depressive-like behaviour of mice? What is the main find …
Protective effect of Melissa officinalis extract against H(2)O(2)-induced oxidative stress in human vascular endothelial cells.
Safaeian L, Sajjadi SE, Javanmard SH, Montazeri H, Samani F. Safaeian L, et al. Res Pharm Sci. 2016 Oct;11(5):383-389. doi: 10.4103/1735-5362.192488. Res Pharm Sci. 2016. PMID: 27920820 Free PMC article.
Melissa officinalis L. is a medicinal plant with a large variety of pharmacological effects and traditional applications. This study aimed to evaluate the protective and antioxidant activities of the extract of M. officinalis aerial parts on human umbilical vein endothelial cells (HUVECs) under oxidative stress induced by H(2)O(2). ...The results revealed antioxidant and cytoprotective effects of M. officinalis against H(2)O(2)-induced oxidative stress in HUVECs. ...
Melissa officinalis L. is a medicinal plant with a large variety of pharmacological effects and traditional applications. This
Lemon balm extract (Melissa officinalis, L.) promotes melanogenesis and prevents UVB-induced oxidative stress and DNA damage in a skin cell model.
Pérez-Sánchez A, Barrajón-Catalán E, Herranz-López M, Castillo J, Micol V. Pérez-Sánchez A, et al. J Dermatol Sci. 2016 Nov;84(2):169-177. doi: 10.1016/j.jdermsci.2016.08.004. Epub 2016 Aug 4. J Dermatol Sci. 2016. PMID: 27528586
Its UVB component (280-315nm) leads to oxidative stress and causes inflammation, DNA damage, p53 induction and lipid and protein oxidation. ...OBJECTIVE: This study evaluates the protective effects of lemon balm extract (LBE) (Melissa Officinalis, L) and its main phenolic compound rosmarinic acid (RA) against UVB-induced damage in human keratinocytes. ...
Its UVB component (280-315nm) leads to oxidative stress and causes inflammation, DNA damage, p53 induction and lipid and protein oxid …
The Protective Effect of Melissa officinalis L. in Visceral Hypersensitivity in Rat Using 2 Models of Acid-induced Colitis and Stress-induced Irritable Bowel Syndrome: A Possible Role of Nitric Oxide Pathway.
Dolatabadi F, Abdolghaffari AH, Farzaei MH, Baeeri M, Ziarani FS, Eslami M, Abdollahi M, Rahimi R. Dolatabadi F, et al. J Neurogastroenterol Motil. 2018 Jul 30;24(3):490-501. doi: 10.5056/jnm17035. J Neurogastroenterol Motil. 2018. PMID: 29879761 Free PMC article.
BACKGROUND/AIMS: The aim of present study is to estimate the effects of Melissa officinalis L. (MO) on visceral hypersensitivity (VH), defecation pattern and biochemical factors in 2 experimental models of irritable bowel syndrome (IBS) and the possible role of nitric oxide. ...In the restraint stress model, the levels of TNF-α, myeloperoxidase, lipid peroxidation, and antioxidant powers were determined in the (removed) colon. ...
BACKGROUND/AIMS: The aim of present study is to estimate the effects of Melissa officinalis L. (MO) on visceral hypersensitivi …
Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances.
Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SG. Cases J, et al. Med J Nutrition Metab. 2011 Dec;4(3):211-218. doi: 10.1007/s12349-010-0045-4. Epub 2010 Dec 17. Med J Nutrition Metab. 2011. PMID: 22207903 Free PMC article.
Melissa officinalis L. has been shown as an anti-stress and anxiolytic agent. We previously reported moderate stress improvement in mice in which Cyracos(®), a standardized Melissa officinalis L. extract, was administrated. ...Our study demonstrates, for the first time that chronic administration of Melissa officinalis L. relieves stress-related effects. ...
Melissa officinalis L. has been shown as an anti-stress and anxiolytic agent. We previously reported moderate stress
Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
Sarris J, McIntyre E, Camfield DA. Sarris J, et al. CNS Drugs. 2013 Apr;27(4):301-19. doi: 10.1007/s40263-013-0059-9. CNS Drugs. 2013. PMID: 23653088 Review.
Support for efficacy was found for chronic use (i.e. greater than one day) of the following herbs in treating a range of anxiety disorders in human clinical trials: Piper methysticum, Matricaria recutita, Ginkgo biloba, Scutellaria lateriflora, Silybum marianum, Passiflora incarnata, Withania somniferum, Galphimia glauca, Centella asiatica, Rhodiola rosea, Echinacea spp., Melissa officinalis and Echium amoenum. ...Acute anxiolytic activity was found for Centella asiatica, Salvia spp., Melissa officinalis, Passiflora incarnata and Citrus aurantium. ...
Support for efficacy was found for chronic use (i.e. greater than one day) of the following herbs in treating a range of anxiety disorders i …
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