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Page 1
The Pharmacological Potential of Novel Melittin Variants from the Honeybee and Solitary Bees against Inflammation and Cancer.
Erkoc P, von Reumont BM, Lüddecke T, Henke M, Ulshöfer T, Vilcinskas A, Fürst R, Schiffmann S. Erkoc P, et al. Toxins (Basel). 2022 Nov 22;14(12):818. doi: 10.3390/toxins14120818. Toxins (Basel). 2022. PMID: 36548715 Free PMC article.
Here, the preclinical pharmacological activities of known and proteo-transcriptomically discovered new melittin variants from the honeybee and more ancestral variants from phylogenetically older solitary bees were explored in the context of cancer and inflamm …
Here, the preclinical pharmacological activities of known and proteo-transcriptomically discovered new melittin variants from the hon …
Anti-Breast Cancer Activity on MCF-7 Cells of Melittin from Indonesia's Apis cerana: An In Vitro Study.
Lischer K, Sitorus SRA, Guslianto BW, Avila F, Khayrani AC, Sahlan M. Lischer K, et al. Asian Pac J Cancer Prev. 2021 Dec 1;22(12):3913-3919. doi: 10.31557/APJCP.2021.22.12.3913. Asian Pac J Cancer Prev. 2021. PMID: 34967571 Free PMC article.
This study aims to evaluate and compare the anti-breast cancer activity of melittin from Indonesia's Apic cerana as a potential drug for treating breast cancer. ...Melittin cytotoxicity was measured with brine shrimp lethality test (BSLT) …
This study aims to evaluate and compare the anti-breast cancer activity of melittin from Indonesia's Apic cerana as a p …
Bee Venom: Composition and Anticancer Properties.
Gajski G, Leonova E, Sjakste N. Gajski G, et al. Toxins (Basel). 2024 Feb 29;16(3):117. doi: 10.3390/toxins16030117. Toxins (Basel). 2024. PMID: 38535786 Free PMC article. Review.
Today, a large number of studies are focused on the antitumor effects of BV, which are mainly attributed to its basic polypeptide melittin (MEL). Previous studies have indicated that BV and its major constituent MEL cause a strong toxic effect on different cancer ce …
Today, a large number of studies are focused on the antitumor effects of BV, which are mainly attributed to its basic polypeptide melitti …
Melittin-A Natural Peptide from Bee Venom Which Induces Apoptosis in Human Leukaemia Cells.
Ceremuga M, Stela M, Janik E, Gorniak L, Synowiec E, Sliwinski T, Sitarek P, Saluk-Bijak J, Bijak M. Ceremuga M, et al. Biomolecules. 2020 Feb 6;10(2):247. doi: 10.3390/biom10020247. Biomolecules. 2020. PMID: 32041197 Free PMC article.
A vast number of studies have been dedicated to the effects of melittin's regulation of apoptosis and to the factors that induce apoptosis in various types of cancer such as breast, ovarian, prostate, lung. ...The aim of our present study is to evaluat …
A vast number of studies have been dedicated to the effects of melittin's regulation of apoptosis and to the factors that indu …
An Updated Review Summarizing the Anticancer Efficacy of Melittin from Bee Venom in Several Models of Human Cancers.
Pandey P, Khan F, Khan MA, Kumar R, Upadhyay TK. Pandey P, et al. Nutrients. 2023 Jul 12;15(14):3111. doi: 10.3390/nu15143111. Nutrients. 2023. PMID: 37513529 Free PMC article. Review.
Thus, this review is targeted toward recapitulating the chemo-preventive potential of melittin (MEL), which constitutes a substantial portion of honeybee venom. Honeybee venom (apitoxin) is produced in the venom gland of the honeybee abdomen, and adult bees utilize …
Thus, this review is targeted toward recapitulating the chemo-preventive potential of melittin (MEL), which constitutes a substantial …