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103,657 results

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Page 1
Critical Insights into Umbilical Cord Blood and Tissue Stem Cells: Navigating Challenges to Enhance Clinical Translation - A Narrative Review.
Fateh K, Atashi A. Fateh K, et al. Stem Cells. 2025 Dec 8:sxaf077. doi: 10.1093/stmcls/sxaf077. Online ahead of print. Stem Cells. 2025. PMID: 41359785
While hematopoietic stem cells from UCB and mesenchymal stem cells from both UCB and UCT are clinically applied, other cord-derived populations remain under investigation, offering novel therapeutic opportunities alongside translational challeng …
While hematopoietic stem cells from UCB and mesenchymal stem cells from both UCB and UCT are clinically a …
Hypoxia-preconditioned hUCMSCs protect frozen-thawed human ovarian tissue by modulating the HIF-1α/VEGF pathway.
Gu M, Ruan X, Cheng J, Li Y, Li Y, Du J, Jin F, Dai Y, Mueck AO. Gu M, et al. Gynecol Endocrinol. 2025 Dec 31;41(1):2597612. doi: 10.1080/09513590.2025.2597612. Epub 2025 Dec 8. Gynecol Endocrinol. 2025. PMID: 41359658
OBJECTIVE: To evaluate whether hypoxia-preconditioned human umbilical cord mesenchymal stem cells (hUCMSCs) can protect frozen-thawed human ovarian tissue via in vitro co-culture. ...
OBJECTIVE: To evaluate whether hypoxia-preconditioned human umbilical cord mesenchymal stem cells (hUCMSCs) can protect …
From water to medicine: the transformative role of hydrogels in diabetic wound healing.
Maurya PK, Hazarika K, Bandyopadhyay-Ghosh S, Nandi SK, Ghosh SB. Maurya PK, et al. J Biomater Sci Polym Ed. 2025 Dec 8:1-26. doi: 10.1080/09205063.2025.2599294. Online ahead of print. J Biomater Sci Polym Ed. 2025. PMID: 41359509 Review.
Finally, we conclude with clinical case studies utilizing hydrogels derived from sodium alginate, placenta-derived mesenchymal stem cells (PDMSC), and collagen-polyacrylate-metal-organic frameworks (MOFs) have shown notable results in wound healing, including …
Finally, we conclude with clinical case studies utilizing hydrogels derived from sodium alginate, placenta-derived mesenchymal ste …
GSTP1-modified exosomes derived from ADMSCs relieve LPS-induced acute lung injury.
Guan H, Du J, Wang X, Zhang Z, Zhou W, Wang F. Guan H, et al. Cytotechnology. 2026 Feb;78(1):9. doi: 10.1007/s10616-025-00863-y. Epub 2025 Dec 5. Cytotechnology. 2026. PMID: 41357851
Acute lung injury (ALI) is a life-threatening critical condition with high mortality. Adipose mesenchymal stem cell (ADMSC)-derived exosomes hold great potential for clinical therapy and drug delivery. ...Exosomes were successfully isolated from ADMSCs, and GSTP1-mo …
Acute lung injury (ALI) is a life-threatening critical condition with high mortality. Adipose mesenchymal stem cell (ADMSC)-de …
Identification of Cystatin 3 as a Potential Diagnostic Biomarker for Osteoporosis Using Machine Learning.
Liu H, Feng Y, Lin B, Zhang L, Wu B, Wu J. Liu H, et al. J Inflamm Res. 2025 Dec 1;18:16805-16823. doi: 10.2147/JIR.S569594. eCollection 2025. J Inflamm Res. 2025. PMID: 41357842 Free PMC article.
A rat model of OP was constructed, and the expression of characteristic genes in bone marrow mesenchymal stem cells (BMSCs) was verified by quantitative real-time polymerase chain reaction (qRT-PCR). ...Immune infiltration analysis revealed that the infiltrat …
A rat model of OP was constructed, and the expression of characteristic genes in bone marrow mesenchymal stem cells (BM …
Rapid cutaneous wound healing in nude mice by fetal skin-derived stem cells involves enhanced collagen secretion and angiogenesis.
Geng Y, Zhang W, Dun X, Wang Y, Shao Y. Geng Y, et al. Front Med (Lausanne). 2025 Nov 20;12:1557973. doi: 10.3389/fmed.2025.1557973. eCollection 2025. Front Med (Lausanne). 2025. PMID: 41357483 Free PMC article.
Stem cells are used to treat chronic non-healing wounds. However, the seed cells required for optimal healing remain unknown. In this study, we evaluate the effects of fetal skin-derived stem cells (FSSCs) on a nude mice cutaneous wound model an …
Stem cells are used to treat chronic non-healing wounds. However, the seed cells required for optimal healing remain un …
Accelerated cartilage regeneration via chondrocyte metabolic reprogramming using nano-steroid-conjugated mesenchymal stem cells in osteoarthritis.
Lee JY, Park JY, Kwon IA, Lim SH, Kim KB, Park JY, Kang YJ, Kim SH, Khang D, Choi JK. Lee JY, et al. Theranostics. 2026 Jan 1;16(2):1023-1044. doi: 10.7150/thno.120765. eCollection 2026. Theranostics. 2026. PMID: 41356803
Background: Osteoarthritis (OA) is a prevalent and debilitating chronic disease for which there are currently no approved disease-modifying osteoarthritis drugs (DMOADs). While mesenchymal stem cells (MSCs) have emerged as promising DMOAD candidates, their cl …
Background: Osteoarthritis (OA) is a prevalent and debilitating chronic disease for which there are currently no approved disease-modifying …
Unravelling the reversion mechanisms of activated hepatic stellate cell properties by extracellular vesicles from mesenchymal stem cells.
Islam MA, Mawya J, Salma U, Abu Kasim NH, Haque N. Islam MA, et al. World J Stem Cells. 2025 Nov 26;17(11):111090. doi: 10.4252/wjsc.v17.i11.111090. World J Stem Cells. 2025. PMID: 41356384 Free PMC article. Review.
Central to the development of fibrosis is the transdifferentiation of quiescent hepatic stellate cells (HSCs) into proliferative and fibrogenic myofibroblast-like activated HSCs (aHSCs), which play a crucial role in extracellular matrix accumulation and fibrotic tissue for …
Central to the development of fibrosis is the transdifferentiation of quiescent hepatic stellate cells (HSCs) into proliferative and …
Application of stem cell-derived exosomes in bone and joint diseases: Recent advances enabled by diverse carrier technologies.
Fu YJ, Jian J, Liu C, Yi YF, Ding YT, Wen J, Li YF, Guo QJ. Fu YJ, et al. World J Stem Cells. 2025 Nov 26;17(11):113631. doi: 10.4252/wjsc.v17.i11.113631. World J Stem Cells. 2025. PMID: 41356383 Free PMC article. Review.
Current treatment modalities possess notable limitations, driving the development of cell-free regenerative treatment strategies centered on stem cell-derived exosomes, particularly mesenchymal stem cell-derived exosomes. Despite the promise of mesenchymal …
Current treatment modalities possess notable limitations, driving the development of cell-free regenerative treatment strategies centered on …
Exosomal delivery of GrpE-like 1 from synovial mesenchymal stem cells activates PINK1-mediated mitophagy for cartilage repair in osteoarthritis.
Phadikar SD, Rajendran RL, Muthu S, Gangadaran P, Ahn BC. Phadikar SD, et al. World J Stem Cells. 2025 Nov 26;17(11):114306. doi: 10.4252/wjsc.v17.i11.114306. World J Stem Cells. 2025. PMID: 41356381 Free PMC article.
GrpE-like 1 (GRPEL1)-carrying exosomes derived from synovial mesenchymal stem cells (SMSC) prevent mitochondrial dysfunction associated with osteoarthritis (OA) by activating PINK1-mediated mitophagy, restoring chondrocyte function, and preserving the extrace …
GrpE-like 1 (GRPEL1)-carrying exosomes derived from synovial mesenchymal stem cells (SMSC) prevent mitochondrial dysfun …
103,657 results
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