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Page 1
Mesenchymal Stem Cells and Purinergic Signaling in Autism Spectrum Disorder: Bridging the Gap between Cell-Based Strategies and Neuro-Immune Modulation.
Wikarska A, Roszak K, Roszek K. Wikarska A, et al. Biomedicines. 2024 Jun 13;12(6):1310. doi: 10.3390/biomedicines12061310. Biomedicines. 2024. PMID: 38927517 Free PMC article. Review.
The prevalence of autism spectrum disorder (ASD) is still increasing, which means that this neurodevelopmental lifelong pathology requires special scientific attention and efforts focused on developing novel therapeutic approaches. It has become increasingly evident …
The prevalence of autism spectrum disorder (ASD) is still increasing, which means that this neurodevelopmental lifelong pathol …
Exosome lncRNA IFNG-AS1 derived from mesenchymal stem cells of human adipose ameliorates neurogenesis and ASD-like behavior in BTBR mice.
Fu Y, Zhang YL, Liu RQ, Xu MM, Xie JL, Zhang XL, Xie GM, Han YT, Zhang XM, Zhang WT, Zhang J, Zhang J. Fu Y, et al. J Nanobiotechnology. 2024 Feb 17;22(1):66. doi: 10.1186/s12951-024-02338-2. J Nanobiotechnology. 2024. PMID: 38368393 Free PMC article.
BACKGROUND: The transplantation of exosomes derived from human adipose-derived mesenchymal stem cells (hADSCs) has emerged as a prospective cellular-free therapeutic intervention for the treatment of neurodevelopmental disorders (NDDs), as well as autism …
BACKGROUND: The transplantation of exosomes derived from human adipose-derived mesenchymal stem cells (hADSCs) has emer …
Mesenchymal stem cell-derived extracellular vesicles alleviate autism by regulating microglial glucose metabolism reprogramming and neuroinflammation through PD-1/PD-L1 interaction.
Qin Q, Fan L, Zeng X, Zheng D, Wang H, Li M, Jiang Y, Wang H, Liu H, Liang S, Wu L, Liang S. Qin Q, et al. J Nanobiotechnology. 2025 Mar 11;23(1):201. doi: 10.1186/s12951-025-03250-z. J Nanobiotechnology. 2025. PMID: 40069859 Free PMC article.
Neuroinflammation triggered by microglia activation is hallmark of autism spectrum disorder (ASD), and this process includes crucial metabolic reprogramming from oxidative phosphorylation to glycolysis, which may cause neuron loss and functional impairment. ...Me …
Neuroinflammation triggered by microglia activation is hallmark of autism spectrum disorder (ASD), and this process includes c …
Mesenchymal Stem Cell-Derived Exosomes as New Remedy for the Treatment of Neurocognitive Disorders.
Harrell CR, Volarevic A, Djonov V, Volarevic V. Harrell CR, et al. Int J Mol Sci. 2021 Feb 1;22(3):1433. doi: 10.3390/ijms22031433. Int J Mol Sci. 2021. PMID: 33535376 Free PMC article. Review.
Mesenchymal stem cell (MSC)-derived exosomes (MSC-Exo) are nano-sized extracellular vesicles enriched with MSC-sourced neuroprotective and immunomodulatory microRNAs, neural growth factors, and anti-inflammatory cytokines, which attenuate neuro-inflammation, promote …
Mesenchymal stem cell (MSC)-derived exosomes (MSC-Exo) are nano-sized extracellular vesicles enriched with MSC-sourced neuropr …
Allogeneic Human Umbilical Cord Mesenchymal Stem Cells for the Treatment of Autism Spectrum Disorder in Children: Safety Profile and Effect on Cytokine Levels.
Riordan NH, Hincapié ML, Morales I, Fernández G, Allen N, Leu C, Madrigal M, Paz Rodríguez J, Novarro N. Riordan NH, et al. Stem Cells Transl Med. 2019 Oct;8(10):1008-1016. doi: 10.1002/sctm.19-0010. Epub 2019 Jun 11. Stem Cells Transl Med. 2019. Retraction in: Stem Cells Transl Med. 2021 Dec;10(12):1717. doi: 10.1002/sct3.13044. PMID: 31187597 Free PMC article. Retracted. Clinical Trial.
Individuals with autism spectrum disorder (ASD) suffer from developmental disabilities that impact communication, behavior, and social interaction. Immune dysregulation and inflammation have been linked to children with ASD, the latter manifesting in serum levels of …
Individuals with autism spectrum disorder (ASD) suffer from developmental disabilities that impact communication, behavior, an …
Mesenchymal stem cells in treating autism: Novel insights.
Siniscalco D, Bradstreet JJ, Sych N, Antonucci N. Siniscalco D, et al. World J Stem Cells. 2014 Apr 26;6(2):173-8. doi: 10.4252/wjsc.v6.i2.173. World J Stem Cells. 2014. PMID: 24772244 Free PMC article. Review.
The core symptoms of ASDs concern the cognitive, emotional, and neurobehavioural domains. The prevalence of autism appears to be increasing at an alarming rate, yet there is a lack of effective and definitive pharmacological options. ...Given the growing awareness of immun …
The core symptoms of ASDs concern the cognitive, emotional, and neurobehavioural domains. The prevalence of autism appears to be incr …
Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders.
Liu Q, Chen MX, Sun L, Wallis CU, Zhou JS, Ao LJ, Li Q, Sham PC. Liu Q, et al. World J Stem Cells. 2019 Feb 26;11(2):55-72. doi: 10.4252/wjsc.v11.i2.55. World J Stem Cells. 2019. PMID: 30842805 Free PMC article. Review.
Autism and autism spectrum disorders (ASD) refer to a range of conditions characterized by impaired social and communication skills and repetitive behaviors caused by different combinations of genetic and environmental influences. ...Given the disturbing rise in the …
Autism and autism spectrum disorders (ASD) refer to a range of conditions characterized by impaired social and communication s …
Banking on teeth - Stem cells and the dental office.
Zeitlin BD. Zeitlin BD. Biomed J. 2020 Apr;43(2):124-133. doi: 10.1016/j.bj.2020.02.003. Epub 2020 May 4. Biomed J. 2020. PMID: 32381462 Free PMC article. Review.
Science and commerce advance together and the stem cell field is no exception. With the promise of cures for conditions as diverse as cancer, autism, neural degeneration, organ replacement and addiction, long-term preservation of dental stem cells is a …
Science and commerce advance together and the stem cell field is no exception. With the promise of cures for conditions as diverse as …
Mesenchymal stem cells in autism spectrum and neurodevelopmental disorders: pitfalls and potential promises.
Simberlund J, Ferretti CJ, Hollander E. Simberlund J, et al. World J Biol Psychiatry. 2015 Sep;16(6):368-375. doi: 10.3109/15622975.2015.1067372. Epub 2015 Jul 31. World J Biol Psychiatry. 2015. PMID: 26230216
OBJECTIVES: In this conceptual review, the authors discuss the promises and pitfalls in the use of mesenchymal stem cells as a potential experimental therapeutic for autism spectrum and other neurodevelopmental disorders. ...Mesenchymal stem …
OBJECTIVES: In this conceptual review, the authors discuss the promises and pitfalls in the use of mesenchymal stem cells …
Mesenchymal Stem Cell-Induced Neuroprotection in Pediatric Neurological Diseases: Recent Update of Underlying Mechanisms and Clinical Utility.
Chen W, Ren Q, Zhou J, Liu W. Chen W, et al. Appl Biochem Biotechnol. 2024 Sep;196(9):5843-5858. doi: 10.1007/s12010-023-04752-y. Epub 2024 Jan 23. Appl Biochem Biotechnol. 2024. PMID: 38261236 Review.
Mesenchymal stem cells (MSCs) have gained significant recognition in this regard due to their ability to differentiate into different cell types. MSCs are multipotent self-replicating stem cells known to render promising results in the treatment …
Mesenchymal stem cells (MSCs) have gained significant recognition in this regard due to their ability to differentiate …
61 results