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2,306 results

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The beneficial effects of mesenchymal stem cells and their exosomes on myocardial infarction and critical considerations for enhancing their efficacy.
Ala M. Ala M. Ageing Res Rev. 2023 Aug;89:101980. doi: 10.1016/j.arr.2023.101980. Epub 2023 Jun 10. Ageing Res Rev. 2023. PMID: 37302757 Review.
Mesenchymal stem cells (MSCs) are multipotent stromal cells with regenerative, anti-inflammatory, and immunomodulatory properties. MSCs and their exosomes significantly improved structural and functional alterations after myocardial infarctio
Mesenchymal stem cells (MSCs) are multipotent stromal cells with regenerative, anti-inflammatory, and immunomodu
Advances in the study of exosomes derived from mesenchymal stem cells and cardiac cells for the treatment of myocardial infarction.
Liu Y, Wang M, Yu Y, Li C, Zhang C. Liu Y, et al. Cell Commun Signal. 2023 Aug 14;21(1):202. doi: 10.1186/s12964-023-01227-9. Cell Commun Signal. 2023. PMID: 37580705 Free PMC article. Review.
Conventional reperfusion therapy can further aggravate myocardial injury. Stem cell therapy, especially with mesenchymal stem cells (MSCs), has emerged as a promising approach to promote cardiac repair and improve cardiac function. ...The presen …
Conventional reperfusion therapy can further aggravate myocardial injury. Stem cell therapy, especially with mesenchymal
Mesenchymal stromal cells for improvement of cardiac function following acute myocardial infarction: a matter of timing.
Barrère-Lemaire S, Vincent A, Jorgensen C, Piot C, Nargeot J, Djouad F. Barrère-Lemaire S, et al. Physiol Rev. 2024 Apr 1;104(2):659-725. doi: 10.1152/physrev.00009.2023. Epub 2023 Aug 17. Physiol Rev. 2024. PMID: 37589393 Free article. Review.
Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains the most common cause of heart failure. ...Due to their biological properties, the use of mesenchymal stromal/stem cells (MSCs) has been considered a pote …
Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains the most common cause of heart fail …
Gelated microvesicle-mediated delivery of mesenchymal stem cell mitochondria for the treatment of myocardial infarction.
Chu Q, He D, Xie W, Li S, Dong Z, Fu X. Chu Q, et al. Proc Natl Acad Sci U S A. 2025 Jul 8;122(27):e2424529122. doi: 10.1073/pnas.2424529122. Epub 2025 Jul 1. Proc Natl Acad Sci U S A. 2025. PMID: 40591606
Mitochondrial dysfunction is closely linked to cardiomyocyte injury following myocardial infarction (MI). While mitochondrial transplantation is a promising therapeutic strategy, challenges remain in maintaining mitochondrial structural integrity, enhancing delivery …
Mitochondrial dysfunction is closely linked to cardiomyocyte injury following myocardial infarction (MI). While mitochondrial …
Mesenchymal stem cell-derived exosomes in cardiovascular and cerebrovascular diseases: From mechanisms to therapy.
Pan Y, Wu W, Jiang X, Liu Y. Pan Y, et al. Biomed Pharmacother. 2023 Jul;163:114817. doi: 10.1016/j.biopha.2023.114817. Epub 2023 May 2. Biomed Pharmacother. 2023. PMID: 37141733 Free article. Review.
In recent years, the focus of research has shifted from the use of mesenchymal stem cells (MSCs) for transplantation to the use of their secretory exosomes (MSC-exosomes) for the treatment of numerous CVDs, including atherosclerosis, myocardial infa
In recent years, the focus of research has shifted from the use of mesenchymal stem cells (MSCs) for transplantation to …
Preconditioned and Genetically Modified Stem Cells for Myocardial Infarction Treatment.
Raziyeva K, Smagulova A, Kim Y, Smagul S, Nurkesh A, Saparov A. Raziyeva K, et al. Int J Mol Sci. 2020 Oct 2;21(19):7301. doi: 10.3390/ijms21197301. Int J Mol Sci. 2020. PMID: 33023264 Free PMC article. Review.
Stem cell transplantation therapy has demonstrated promising results in improving heart function following myocardial infarction. ...In this review, we discuss the most up-to-date findings related to utilizing preconditioned stem cells for my
Stem cell transplantation therapy has demonstrated promising results in improving heart function following myocardial infar
Stem cell therapy for acute myocardial infarction - focusing on the comparison between Muse cells and mesenchymal stem cells.
Yamada Y, Minatoguchi S, Kanamori H, Mikami A, Okura H, Dezawa M, Minatoguchi S. Yamada Y, et al. J Cardiol. 2022 Jul;80(1):80-87. doi: 10.1016/j.jjcc.2021.10.030. Epub 2021 Dec 17. J Cardiol. 2022. PMID: 34924234 Free article. Review.
Rapid percutaneous coronary intervention for acute myocardial infarction (AMI) reduces acute mortality, but there is an urgent need for treatment of left ventricular dysfunction and remodeling after AMI to improve the prognosis. ...It has been reported that bone mar …
Rapid percutaneous coronary intervention for acute myocardial infarction (AMI) reduces acute mortality, but there is an urgent …
Research and application of hydrogel-encapsulated mesenchymal stem cells in the treatment of myocardial infarction.
Guan H, Chen Y, Liu X, Huang L. Guan H, et al. Colloids Surf B Biointerfaces. 2024 Jul;239:113942. doi: 10.1016/j.colsurfb.2024.113942. Epub 2024 May 6. Colloids Surf B Biointerfaces. 2024. PMID: 38729022 Review.
Myocardial infarction (MI) stands out as a highly lethal disease that poses a significant threat to global health. Worldwide, heart failure resulting from MI remains a leading cause of human mortality. Mesenchymal stem cell (MSC) therapy has emerged as
Myocardial infarction (MI) stands out as a highly lethal disease that poses a significant threat to global health. Worldwide,
Extracellular Vesicles from NMN Preconditioned Mesenchymal Stem Cells Ameliorated Myocardial Infarction via miR-210-3p Promoted Angiogenesis.
Pu Y, Li C, Qi X, Xu R, Dong L, Jiang Y, Gong Q, Wang D, Cheng R, Zhang C, Chen Y. Pu Y, et al. Stem Cell Rev Rep. 2023 May;19(4):1051-1066. doi: 10.1007/s12015-022-10499-6. Epub 2023 Jan 25. Stem Cell Rev Rep. 2023. PMID: 36696015 Free PMC article.
Mesenchymal stem cell-derived extracellular vesicles (MSCs-EVs) possess cardioprotection in acute myocardial infarction. ...Knockdown of miR-210-3p in N-EVs significantly impaired its ability to protect the heart after myocardial infarction
Mesenchymal stem cell-derived extracellular vesicles (MSCs-EVs) possess cardioprotection in acute myocardial infarct
Mechanistic effects of mesenchymal and hematopoietic stem cells: New therapeutic targets in myocardial infarction.
Shafei AE, Ali MA, Ghanem HG, Shehata AI, Abdelgawad AA, Handal HR, ElSayed AS, Ashaal AE, Ali MM, El-Shal AS. Shafei AE, et al. J Cell Biochem. 2018 Jul;119(7):5274-5286. doi: 10.1002/jcb.26637. Epub 2018 Mar 12. J Cell Biochem. 2018. PMID: 29266431 Review.
Myocardial infarction (MI) results in dysfunction and irreversible loss of cardiomyocytes and is of the most serious health threats today. Mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs) have been explored as prom
Myocardial infarction (MI) results in dysfunction and irreversible loss of cardiomyocytes and is of the most serious health th
2,306 results