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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1872 2
1873 1
1880 1
1881 1
1890 1
1891 1
1893 1
1895 1
1896 1
1897 5
1898 2
1899 5
1900 6
1901 10
1902 5
1903 5
1904 2
1905 11
1906 7
1907 11
1908 8
1909 13
1910 13
1911 18
1912 19
1913 11
1914 18
1915 13
1916 11
1917 11
1918 15
1919 11
1920 17
1921 19
1922 18
1923 17
1924 35
1925 45
1926 55
1927 47
1928 45
1929 43
1930 34
1931 52
1932 77
1933 58
1934 74
1935 74
1936 73
1937 73
1938 67
1939 70
1940 56
1941 54
1942 43
1943 42
1944 40
1945 615
1946 1896
1947 2125
1948 2305
1949 1864
1950 2014
1951 4078
1952 6694
1953 8024
1954 8667
1955 9587
1956 10278
1957 11677
1958 12333
1959 12744
1960 12862
1961 14420
1962 12331
1963 11604
1964 18188
1965 22248
1966 30157
1967 38704
1968 45586
1969 49601
1970 52015
1971 56860
1972 62026
1973 65115
1974 69446
1975 70542
1976 69923
1977 71316
1978 72591
1979 76445
1980 79438
1981 79769
1982 83796
1983 85833
1984 90704
1985 94947
1986 97139
1987 98317
1988 103335
1989 111582
1990 118832
1991 120810
1992 123763
1993 128095
1994 133168
1995 138281
1996 139184
1997 142520
1998 148848
1999 153483
2000 165797
2001 176277
2002 183719
2003 195940
2004 208738
2005 226369
2006 241967
2007 254684
2008 267029
2009 278207
2010 297738
2011 318313
2012 332777
2013 343610
2014 344590
2015 347306
2016 338498
2017 335767
2018 338859
2019 345549
2020 341911
2021 317205
2022 278117
2023 247228
2024 84366

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9,318,890 results

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Page 1
Metabolic Heterogeneity and Cross-Feeding in Bacterial Multicellular Systems.
Evans CR, Kempes CP, Price-Whelan A, Dietrich LEP. Evans CR, et al. Trends Microbiol. 2020 Sep;28(9):732-743. doi: 10.1016/j.tim.2020.03.008. Epub 2020 Apr 23. Trends Microbiol. 2020. PMID: 32781027 Free PMC article. Review.
Here, we discuss examples of bacterial differentiation, focusing on cases in which distinct metabolisms coexist and those that exhibit cross-feeding, with one subpopulation producing substrates that are metabolized by a second subpopulation. We describe several stud …
Here, we discuss examples of bacterial differentiation, focusing on cases in which distinct metabolisms coexist and those that exhibi …
Metabolic polymorphisms.
Daly AK, Cholerton S, Gregory W, Idle JR. Daly AK, et al. Pharmacol Ther. 1993 Feb-Mar;57(2-3):129-60. doi: 10.1016/0163-7258(93)90053-g. Pharmacol Ther. 1993. PMID: 8361990 Review.
Examples of this class include the cytochrome P450 enzymes CYP2A6, CYP2E1, CYP2C9 and CYP3A4, xanthine oxidase, an S-oxidase which metabolizes carbocysteine, epoxide hydrolase, two forms of sulphotransferase and several methyltransferases. The nature of all these polymorph …
Examples of this class include the cytochrome P450 enzymes CYP2A6, CYP2E1, CYP2C9 and CYP3A4, xanthine oxidase, an S-oxidase which metabo …
Liver glucose metabolism in humans.
Adeva-Andany MM, Pérez-Felpete N, Fernández-Fernández C, Donapetry-García C, Pazos-García C. Adeva-Andany MM, et al. Biosci Rep. 2016 Nov 29;36(6):e00416. doi: 10.1042/BSR20160385. Print 2016 Dec. Biosci Rep. 2016. PMID: 27707936 Free PMC article. Review.
In addition, liver glucose metabolism is involved in glycosylation reactions and connected with fatty acid metabolism. ...Glucokinase phosphorylates glucose to glucose 6-phosphate inside the hepatocyte, ensuring that an adequate flow of glucose enters the cell to be …
In addition, liver glucose metabolism is involved in glycosylation reactions and connected with fatty acid metabolism. ...Gluc …
[The metabolism of alcohol].
Paquot N. Paquot N. Rev Med Liege. 2019 May;74(5-6):265-267. Rev Med Liege. 2019. PMID: 31206264 Free article. French.
Two systems contribute to this metabolization, the predominant alcohol dehydrogenase pathway, and the pathway controlled by the microsomal ethanol oxidizing system (MEOS), which is inducible and is also involved in the metabolism of other drugs. Acetaldehyde is then …
Two systems contribute to this metabolization, the predominant alcohol dehydrogenase pathway, and the pathway controlled by the micro …
Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets.
Wang B, Wu L, Chen J, Dong L, Chen C, Wen Z, Hu J, Fleming I, Wang DW. Wang B, et al. Signal Transduct Target Ther. 2021 Feb 26;6(1):94. doi: 10.1038/s41392-020-00443-w. Signal Transduct Target Ther. 2021. PMID: 33637672 Free PMC article. Review.
This review sets out to summarize the physiological and pathophysiological importance of the AA metabolizing pathways and outline the molecular mechanisms underlying the actions of AA related to its three main metabolic pathways in CVD and cancer progression will pr …
This review sets out to summarize the physiological and pathophysiological importance of the AA metabolizing pathways and outline the …
Improved succinate production by metabolic engineering.
Cheng KK, Wang GY, Zeng J, Zhang JA. Cheng KK, et al. Biomed Res Int. 2013;2013:538790. doi: 10.1155/2013/538790. Epub 2013 Apr 18. Biomed Res Int. 2013. PMID: 23691505 Free PMC article. Review.
The history of the biosuccinate production shows that the joint effort of different metabolic engineering approaches brings successful results. In order to enhance the succinate production, multiple metabolical strategies have been sought. In this review, different …
The history of the biosuccinate production shows that the joint effort of different metabolic engineering approaches brings successfu …
Metabolic pathways of methylmercury in rotifer Brachionus plicatilis.
Lin H, Mao X, Wei Y, Li S, Qin J, Zhu S, Su S, He T. Lin H, et al. Sci Total Environ. 2023 Dec 20;905:167063. doi: 10.1016/j.scitotenv.2023.167063. Epub 2023 Sep 13. Sci Total Environ. 2023. PMID: 37709075
In contrast, exposure of rotifers to MeHg via food intake appeared to influence carbon, galactose, alanine, aspartate and glutamate metabolisms. Besides, the disturbed biological pathways such as histidine metabolism, beta-alanine metabolism and pantothenate …
In contrast, exposure of rotifers to MeHg via food intake appeared to influence carbon, galactose, alanine, aspartate and glutamate metab …
miRNAs link metabolic reprogramming to oncogenesis.
Hatziapostolou M, Polytarchou C, Iliopoulos D. Hatziapostolou M, et al. Trends Endocrinol Metab. 2013 Jul;24(7):361-73. doi: 10.1016/j.tem.2013.03.002. Epub 2013 Apr 19. Trends Endocrinol Metab. 2013. PMID: 23602813 Review.
The most profound biochemical phenotype of cancer cells is their ability to metabolize glucose to lactate, even under aerobic conditions. This alternative metabolic circuitry is sufficient to support the biosynthetic and energy requirements for cancer cell prolifera …
The most profound biochemical phenotype of cancer cells is their ability to metabolize glucose to lactate, even under aerobic conditi …
Metabolic drug interactions with newer antipsychotics: a comparative review.
Spina E, de Leon J. Spina E, et al. Basic Clin Pharmacol Toxicol. 2007 Jan;100(1):4-22. doi: 10.1111/j.1742-7843.2007.00017.x. Basic Clin Pharmacol Toxicol. 2007. PMID: 17214606 Free article. Review.
Quetiapine is metabolized by CYP3A4, while sertindole and aripiprazole are metabolized by CYP2D6 and CYP3A4. ...Most documented metabolic interactions involve antidepressant and anti-epileptic drugs. ...
Quetiapine is metabolized by CYP3A4, while sertindole and aripiprazole are metabolized by CYP2D6 and CYP3A4. ...Most documente …
Metabolic engineering for improved fermentation of pentoses by yeasts.
Jeffries TW, Jin YS. Jeffries TW, et al. Appl Microbiol Biotechnol. 2004 Feb;63(5):495-509. doi: 10.1007/s00253-003-1450-0. Epub 2003 Nov 1. Appl Microbiol Biotechnol. 2004. PMID: 14595523 Review.
The fermentation of xylose is essential for the bioconversion of lignocellulose to fuels and chemicals, but wild-type strains of Saccharomyces cerevisiae do not metabolize xylose, so researchers have engineered xylose metabolism in this yeast. ...Anaerobic growth by …
The fermentation of xylose is essential for the bioconversion of lignocellulose to fuels and chemicals, but wild-type strains of Saccharomyc …
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